Revista espanola de cardiologia最新文献

{"title":"Abordaje del tratamiento antitrombótico durante el perioperatorio y el periprocedimiento: documento de consenso 2025 de SEC, SEDAR, SEACV, SECCE, AEC, SECOM CYC, SECPRE, SEPD, SEGG, SEGO, SEHH, SETH, SEMERGEN, SEMFYC, SEMG, SEMICYUC, SEMI, SEMES, SEN, S.E.N., SENEC, SEPAR, SEO, SEORL-CCC, SEPA, SERVEI, SECOT y AEU","authors":"David Vivas ,&nbsp;Raquel Ferrandis ,&nbsp;Manuel Anguita-Sánchez ,&nbsp;María Anguita-Gámez ,&nbsp;Juan Ignacio Arcelus ,&nbsp;Marysol Echeverri ,&nbsp;Isabel Egocheaga ,&nbsp;María Asunción Esteve-Pastor ,&nbsp;José Luis Ferreiro ,&nbsp;Juan Vicente Llau ,&nbsp;Vanessa Roldán ,&nbsp;Juan Miguel Ruiz-Nodar ,&nbsp;David González-Casal ,&nbsp;Mónica Torres-Fonseca ,&nbsp;José López-Menéndez ,&nbsp;Míriam Ciria ,&nbsp;Francisco Leyva ,&nbsp;Enrique Rodríguez de Santiago ,&nbsp;María Teresa Vidán ,&nbsp;Loida Pamplona ,&nbsp;Nora Palomo-López","doi":"10.1016/j.recesp.2025.07.008","DOIUrl":"10.1016/j.recesp.2025.07.008","url":null,"abstract":"<div><div>In recent years, the use of anticoagulant and antiplatelet medications has significantly increased, along with rising life expectancy. As a result, many patients on antithrombotic therapy will eventually require invasive procedures. This necessitates decisions on the appropriateness and timing of discontinuing anticoagulation and/or antiplatelet therapy in each case. Although a key multidisciplinary consensus document was published in 2018 to guide this process, its practical application has been limited. Furthermore, adherence to its recommendations has been low, leading to a higher incidence of both thrombotic and hemorrhagic adverse events. To address these issues and reflect advances in knowledge, it has been decided to update the previous consensus document to include developments since 2018. The aim is to simplify clinical decision-making and gain support from a broader range of scientific societies. Ultimately, the goal is to improve the dissemination and practical application of these recommendations to optimize the safety and effectiveness of antithrombotic treatment in patients requiring invasive procedures, reduce complications associated with inappropriate treatment, and enhance clinical outcomes in this increasingly complex scenario.</div><div><em>Full English text available from</em>:<span><span>www.revespcardiol.org/en</span><svg><path></path></svg></span></div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 1","pages":"Pages 68-79"},"PeriodicalIF":5.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145824212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modelando el pronóstico en la insuficiencia tricuspídea grave a través del acoplamiento entre el ventrículo derecho y la arteria pulmonar","authors":"Dalila Nappa ,&nbsp;Rocío Hinojar ,&nbsp;Covadonga Fernández-Golfín","doi":"10.1016/j.recesp.2025.06.012","DOIUrl":"10.1016/j.recesp.2025.06.012","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 1","pages":"Pages 46-48"},"PeriodicalIF":5.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145824171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asociación entre fibrilación auricular y demencia en un estudio poblacional a gran escala en el sur de Europa","authors":"Julián Rodríguez-García ,&nbsp;Rafel Ramos ,&nbsp;Anna Ponjoan ,&nbsp;Jordi Blanch ,&nbsp;Miguel Cainzos-Achirica ,&nbsp;Paolo D. Dallaglio ,&nbsp;Rodolfo San Antonio ,&nbsp;Marcos Rodríguez-García ,&nbsp;Jordi Mercé ,&nbsp;Valentina Faga ,&nbsp;Javier Sanaú ,&nbsp;Ismael Almonte ,&nbsp;Jesús Rodríguez-Silva ,&nbsp;Josep Comín-Colet ,&nbsp;Ignasi Anguera ,&nbsp;Andrea Di Marco","doi":"10.1016/j.recesp.2025.05.009","DOIUrl":"10.1016/j.recesp.2025.05.009","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The association between atrial fibrillation (AF) and dementia remains debated, and data from Mediterranean populations are scarce. We aimed to evaluate the relationship between AF and dementia in a large Catalan cohort, with a particular focus on identifying subgroups with the strongest associations.</div></div><div><h3>Methods</h3><div>We conducted a population-based observational study including individuals aged ≥<!--> <!-->45 years without prior diagnosis of dementia. Data were obtained from the System for the Development of Research in Primary Care, which covers more than 80% of the Catalan population. Dementia was identified using ICD-10-CM codes and prescription records. Early-onset dementia (EOD) was defined as diagnosis before age 65 years. Participants were followed up from 2009 to 2021. Cox regression models were used to identify predictors of incident dementia.</div></div><div><h3>Results</h3><div>A total of 2 520 839 individuals were included (mean follow-up: 13 years), of whom 79820 (3.25%) had AF at baseline. On univariate analysis, AF was a strong predictor of dementia (HR, 3.39; <em>P</em> <!-->&lt;<!--> <!-->.001). However, after multivariable adjustment, the association was modest (HR, 1.04; <em>P</em> <!-->&lt;<!--> <!-->.001). AF was a stronger independent predictor in individuals aged &lt;<!--> <!-->70 years (HR, 1.21; <em>P</em> <!-->&lt;<!--> <!-->.001), whereas the association was not significant in those aged ≥70. The strongest association was observed for EOD (HR, 1.36; <em>P</em> <!-->&lt;<!--> <!-->.001). All associations remained consistent in analyses restricted to individuals without prior stroke.</div></div><div><h3>Conclusions</h3><div>In a large Mediterranean cohort, AF was independently associated with a modest increase in dementia risk, regardless of stroke. This association was stronger in younger individuals and in EOD. These findings highlight the need for studies assessing the impact of early identification and management of AF on dementia incidence in younger populations.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 1","pages":"Pages 24-34"},"PeriodicalIF":5.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145824170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevención primaria en personas mayores: diferencias por sexo en la persistencia al tratamiento con estatinas y el control del colesterol","authors":"Sara Malo ,&nbsp;María José Rabanaque ,&nbsp;Adriana Gamba ,&nbsp;José Manuel Vinuesa-Hernando ,&nbsp;Aida Moreno-Juste ,&nbsp;María Jesús Lallana ,&nbsp;Jesús Cebollada ,&nbsp;Isabel Aguilar-Palacio","doi":"10.1016/j.recesp.2025.05.007","DOIUrl":"10.1016/j.recesp.2025.05.007","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>This study aimed to analyze sex differences in statin persistence and associated factors among individuals aged 70 years and older in Spain who initiated statin therapy for primary prevention of cardiovascular disease. Additionally, it assessed the role of sex in low-density lipoprotein cholesterol (LDL-C) control based on the intensity of statin therapy used.</div></div><div><h3>Methods</h3><div>This was an observational longitudinal study conducted within the CARhES (Cardiovascular risk factors for health services research) cohort. Individuals aged ≥ 70 years who initiated statin therapy for primary prevention of cardiovascular disease between 2018 and 2020 were included. Two-year statin persistence was assessed by sex. Considering major cardiovascular events and death as competing risks, the risk of statin discontinuation and its associated factors were estimated using cumulative incidence functions and Fine and Gray analysis. The proportion of men and women achieving LDL-C target levels was also calculated.</div></div><div><h3>Results</h3><div>A total of 4936 older adults (61.7% women) were included. Compared with men, women had higher mean LDL-C levels prior to statin initiation, a greater pharmacological burden, were less likely to receive high-intensity statins, and demonstrated lower persistence. No variables were statistically associated with discontinuation among women. In men, the adjusted HR for discontinuation was 1.03 (95%CI: 1.00-1.06) per 10<!--> <!-->mg/dL increase in baseline LDL-C level. Among persistent statin users, women were less likely than men to achieve LDL-C targets, particularly when treated with low- to moderate-intensity statins.</div></div><div><h3>Conclusions</h3><div>Significant sex differences exist in statin persistence, associated factors, and achievement of LDL-C targets among older adults. These findings highlight the importance of considering sex-specific factors when evaluating the appropriateness of statin use in this population.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 1","pages":"Pages 15-23"},"PeriodicalIF":5.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145824172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Afectación cardiaca poco común en osteosarcoma metastásico","authors":"Juan Manuel Serrano-Marcos ,&nbsp;Víctor Manuel López-Espinosa ,&nbsp;Míriam Cantero-Campos","doi":"10.1016/j.recesp.2025.04.008","DOIUrl":"10.1016/j.recesp.2025.04.008","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 12","pages":"Pages 1130-1131"},"PeriodicalIF":5.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Miocarditis por vasculitis de vaso pequeño: una etiología infrecuente","authors":"Alejandro Gullón de la Roza ,&nbsp;María Salgado Barquinero ,&nbsp;María Fernández García ,&nbsp;Beatriz Nieves Ureña ,&nbsp;Fernando López Iglesias ,&nbsp;María Martín Fernández","doi":"10.1016/j.recesp.2025.06.001","DOIUrl":"10.1016/j.recesp.2025.06.001","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 12","pages":"Pages 1115-1117"},"PeriodicalIF":5.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implante de Impella por tronco braquiocefálico: una alternativa para soporte izquierdo en accesos axilares pequeños","authors":"Enrique Pérez-de la Sota,&nbsp;Andrea Eixerés-Esteve,&nbsp;Jorge Enrique Centeno-Rodríguez,&nbsp;María Jesús López-Gude,&nbsp;Christian Muñoz-Guijosa","doi":"10.1016/j.recesp.2025.02.021","DOIUrl":"10.1016/j.recesp.2025.02.021","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 12","pages":"Pages 1124-1126"},"PeriodicalIF":5.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Registro español de ablación con catéter. XXIV informe oficial de la Asociación del Ritmo Cardiaco de la Sociedad Española de Cardiología (2024)","authors":"Eduardo Arana-Rueda ,&nbsp;José Manuel Rubio-Campal ,&nbsp;Bieito Campos ,&nbsp;Felipe Rodríguez-Entem ,&nbsp;David Calvo ,&nbsp;en representación de los colaboradores del Registro español de ablación con catéter","doi":"10.1016/j.recesp.2025.08.001","DOIUrl":"10.1016/j.recesp.2025.08.001","url":null,"abstract":"<div><h3>Introduction</h3><div>This report presents the results of the Spanish catheter ablation registry for 2024.</div></div><div><h3>Methods</h3><div>A retrospective analysis of ablation procedures performed at participating hospitals in Spain. Data were collected through the REDCap platform using a dedicated form.</div></div><div><h3>Results</h3><div>There was a significant increase in both the number of participating centers (117 centers,<!--> <!-->+<!--> <!-->12.5%) and the total number of ablations performed (32 406,<!--> <!-->+<!--> <!-->23%). The most common arrhythmogenic substrate was atrial fibrillation (13 395 cases,<!--> <!-->+<!--> <!-->35%, accounting for 41% of all cases), with the single-shot technique being the most widely used (55%). There was also a marked increase in the use of electroporation (21% in 2024 vs 10.3% in 2023). Other substrates showed smaller increases, with cavotricuspid isthmus ablation maintaining its position as the second most common procedure (6084 cases, 19%). Overall acute success rates remained high (95%), and complication (1.5%) and mortality (0.04%) rates were stable. The use of electroanatomical navigation remained consistent (54% of cases), with 17% of procedures performed without fluoroscopy. Outpatient procedures accounted for 18% of the total, with notable percentages for atrioventricular nodal re-entrant tachycardia (39%) and cavotricuspid isthmus ablation (33%). A total of 523 pediatric ablations were performed in 44 centers, predominantly for accessory pathways (66.5%), with a 92.5% success rate. Accreditation activity showed 41 centers and 250 professionals involved.</div></div><div><h3>Conclusions</h3><div>The number of centers and procedures increased, mainly due to atrial fibrillation ablation. Despite the growing complexity of cases, the rates of success, complications, and mortality remained stable. The accreditation process for both centers and professionals is now firmly established, with steady annual accreditation numbers.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 12","pages":"Pages 1088-1099"},"PeriodicalIF":5.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abordaje y consumo de recursos sanitarios en la miocardiopatía hipertrófica obstructiva en España: un estudio de la vida real","authors":"Roberto Barriales-Villa ,&nbsp;Luis Escobar-López ,&nbsp;David Vilanova Larena ,&nbsp;Joel Salazar-Mendiguchía ,&nbsp;Ainara Echeto ,&nbsp;Ignacio Hernández ,&nbsp;Elena Rebollo-Gómez ,&nbsp;Juan Ramón Gimeno","doi":"10.1016/j.recesp.2025.04.004","DOIUrl":"10.1016/j.recesp.2025.04.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Obstructive hypertrophic cardiomyopathy (oHCM), whose symptoms range from dyspnea to heart failure or sudden cardiac death, accounts for approximately 70% of all hypertrophic cardiomyopathy cases. This study aimed to analyze the lack of comprehensive data on oHCM management and determine its clinical and economic burden in Spain.</div></div><div><h3>Methods</h3><div>This retrospective observational study, based on electronic medical records (BIG-PAC), enrolled adults from 1 January 2014, to 31 October 2022, from the time of HCM diagnosis. The analysis focused on epidemiology, patient characteristics and management, transitions between New York Heart Association (NYHA) functional classes, healthcare resource utilization (HCRU), and associated costs.</div></div><div><h3>Results</h3><div>A total of 752 oHCM patients were included (mean age: 63 years; male: 57.6%). NYHA functional classification at diagnosis was as follows: 12% NYHA-I, 47.9% NYHA-II, 31.5% NYHA-III, and 8.6% NYHA-IV. The prevalence of HCM and oHCM was 28 and 7 per 10 000 individuals, respectively. Patients received a mean of 2.4 (SD 1.5) treatments, mainly beta-blockers. Only patients in NYHA classes III and IV underwent septal reduction therapies (SRT) (13.1% and 47.7%, respectively); 38.7% and 35.5% of NYHA-III and -IV patients who received SRT, respectively, improved to a lower NYHA class. Symptom severity, as measured by NYHA class, was associated with increased rates of hospitalization, cardiovascular events, mortality, and higher HCRU and costs. Mean annualized, direct, adjusted health care costs ranged from €4142 (95%CI: €3110-€5175) in NYHA-I to €16 677 (95%CI: €15 482-€17 872) in NYHA-IV.</div></div><div><h3>Conclusions</h3><div>This is the first Spanish study to evaluate oHCM patient management and to demonstrate its impact in terms of increased hospitalizations, mortality, HCRU, and healthcare costs, trends that parallel the progression of symptoms by NYHA functional class. Patients who underwent SRT showed partial symptom improvement.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 12","pages":"Pages 1041-1053"},"PeriodicalIF":5.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consecuencias clínicas de los límites superiores de referencia ajustados al sexo de la troponina cardiaca I ultrasensible en el diagnóstico del infarto agudo de miocardio","authors":"María Rubini Giménez ,&nbsp;Luca Koechlin ,&nbsp;Pedro López-Ayala ,&nbsp;Carlos Spagnuolo ,&nbsp;Jasper Boeddinghaus ,&nbsp;Karin Wildi ,&nbsp;Thomas Nestelberger ,&nbsp;Hanna Tkachenko ,&nbsp;Daniel Basic ,&nbsp;Emel Kaplan ,&nbsp;Jude Formambuh ,&nbsp;Paolo Bima ,&nbsp;Jonas Glaeser ,&nbsp;Luca Crisanti ,&nbsp;Óscar Miró ,&nbsp;F. Javier Martín-Sánchez ,&nbsp;Michael Christ ,&nbsp;Dagmar I. Keller ,&nbsp;Danielle M. Gualandro ,&nbsp;Damian Kawecki ,&nbsp;Arnold von Eckardstein","doi":"10.1016/j.recesp.2025.05.001","DOIUrl":"10.1016/j.recesp.2025.05.001","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>It is unclear whether applying sex-specific rather than uniform upper reference limits (URLs) for high-sensitivity cardiac troponin I (hs-cTnI) improves diagnostic equity between women and men with suspected myocardial infarction (MI). We compared the diagnostic performance of these 2 approaches.</div></div><div><h3>Methods</h3><div>In an international, prospective, multicenter study of patients presenting with suspected MI, the final diagnosis was centrally adjudicated twice by 2 independent cardiologists using all available information, including serial measurements of hs-cTnI-Architect, once using the uniform URL (26.2 ng/L) and once using sex-specific URLs (women: 15.6 ng/L; men: 34.2 ng/L). The primary outcome was the diagnostic performance of uniform vs sex-specific URLs at presentation for MI.</div></div><div><h3>Results</h3><div>Among 7137 eligible patients, 2434 were women (34%), median age 65 years, and 4703 were men (66%), median age 59 years. Using the uniform URL, 348 women and 880 men were adjudicated as having MI. At presentation, the sensitivity and specificity of hs-cTnI were high and similar in women (77%; 95%CI, 72-81, and 93%; 95%CI, 92-94, respectively) and men (79%; 95%CI, 77-82, and 94%; 95%CI, 93-94). Using sex-specific URLs, the sensitivity and specificity were 85% (95%CI, 81-89) and 91% (95%CI, 89-92) in women vs 74% (95%CI, 71-77), and 95% (95%CI, 94-95) in men (<em>P</em> <!-->&lt;<!--> <!-->.001). Using sex-specific URLs, diagnostic reclassification occurred in 27 patients, 12 women (upgrade to MI) and 15 men (downgrade from MI), representing 0.4%, (95%CI, 0.3-0.6) of all patients.</div></div><div><h3>Conclusions</h3><div>Using a uniform URL for hs-cTnI provides high and similar diagnostic sensitivity and specificity in women and men. Contrary to expectations, sex-specific URLs introduced sex-related disparities. These findings support the use of a uniform rather than sex-specific URL in the diagnosis of MI.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 12","pages":"Pages 1064-1075"},"PeriodicalIF":5.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}