Revista Iberoamericana De Micologia最新文献_第10页

Tsunamis and changes in the etiology of the canine and feline cryptococcosis 海啸和犬猫隐球菌病病因学的变化

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2019.12.002

F. Javier Cabañes

引用次数: 0

Rhodotorula dairenensis fungemia in a patient with cancer 癌症患者的戴氏红酵母菌血症

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2020.03.006

Fernando Cobo , Óscar Zaragoza , José María Navarro-Marí

引用次数: 2

Diversity and adaptation within the genus Malassezia: Bats already have their species 马拉色属的多样性和适应性:蝙蝠已经有了自己的物种

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2019.12.001

F. Javier Cabañes

引用次数: 2

Micosis cutánea por Curvularia pallescens en un paciente trasplantado pulmonar: primer caso descrito en España 肺移植患者的皮肤真菌病:西班牙首次描述的病例

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2020.03.005

Sheila Requena López , Patricia Morales del Burgo , Santiago Gómez Díez , Jose Antonio Boga , Teresa Peláez García de la Rasilla

{"title":"Micosis cutánea por Curvularia pallescens en un paciente trasplantado pulmonar: primer caso descrito en España","authors":"Sheila Requena López , Patricia Morales del Burgo , Santiago Gómez Díez , Jose Antonio Boga , Teresa Peláez García de la Rasilla","doi":"10.1016/j.riam.2020.03.005","DOIUrl":"10.1016/j.riam.2020.03.005","url":null,"abstract":"<div><h3>Background</h3><p><em>Curvularia</em> is a filamentous dematiaceous fungus increasingly recognized as a pathogen in immunocompromised patients. The most common clinical entities associated with this fungus are allergic sinusitis, cutaneous infection and keratitis. In this article, a report on the first clinical case of <em>Curvularia pallescens</em> cutaneous infection in Spain and its treatment is described.</p></div><div><h3>Case report</h3><p>A 68 year-old man with a history of lung transplantation presented to Dermatology Unit due to a skin lesion in the knee that had been evolving for 6 months. A skin biopsy was performed for its study. In the histopathological study, an intense and non-specific inflammatory reaction in the dermis was observed, and with Grocott stain and periodic acid Schiff abundant septate hyphae and spores were found in the dermis. The culture of the sample revealed a filamentous fungus whose microscopic examination allowed to identify the genus as <em>Curvularia</em>. Using MALDI-TOF mass spectrometry and molecular identification, the fungus was finally identified as <em>Curvularia pallescens.</em> The patient underwent surgical resection of the lesion and was treated with posaconazole, evolving favorably.</p></div><div><h3>Conclusions</h3><p>The species of <em>Curvularia</em> should be considered causal agents of fungal skin infections in immunosuppressed patients. This clinical case, which showed good clinical response after surgical resection and treatment with posaconazole, is the first described in Spain due to this species.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2020.03.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38077561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fungal co-infection in COVID-19 patients: Should we be concerned? COVID-19患者的真菌合并感染:我们应该关注吗?

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2020.07.001

Javier Pemán , Alba Ruiz-Gaitán , Carolina García-Vidal , Miguel Salavert , Paula Ramírez , Francesc Puchades , Marta García-Hita , Ana Alastruey-Izquierdo , Guillermo Quindós

{"title":"Fungal co-infection in COVID-19 patients: Should we be concerned?","authors":"Javier Pemán , Alba Ruiz-Gaitán , Carolina García-Vidal , Miguel Salavert , Paula Ramírez , Francesc Puchades , Marta García-Hita , Ana Alastruey-Izquierdo , Guillermo Quindós","doi":"10.1016/j.riam.2020.07.001","DOIUrl":"10.1016/j.riam.2020.07.001","url":null,"abstract":"<div><p>Critically ill COVID-19 patients have higher pro-inflammatory (IL-1, IL-2, IL-6, tumor necrosis alpha) and anti-inflammatory (IL-4, IL-10) cytokine levels, less CD<sub>4</sub> interferon-gamma expression, and fewer CD<sub>4</sub> and CD<sub>8</sub> cells. This severe clinical situation increases the risk of serious fungal infections, such as invasive pulmonary aspergillosis, invasive candidiasis or <em>Pneumocystis jirovecii</em> pneumonia. However, few studies have investigated fungal coinfections in this population. We describe an update on published reports on fungal coinfections and our personal experience in three Spanish hospitals. We can conclude that despite the serious disease caused by SARS-CoV-2 in many patients, the scarcity of invasive mycoses is probably due to the few bronchoscopies and necropsies performed in these patients because of the high risk in aerosol generation. However, the presence of fungal markers in clinically relevant specimens, with the exception of bronchopulmonary colonization by <em>Candida</em>, should make it advisable to early implement antifungal therapy.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2020.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38474990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 124

Congenital cutaneous candidiasis associated with maternal peripartum candidemia 先天性皮肤念珠菌病与母体围产期念珠菌血症相关

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2020.02.002

Mario Fernández-Ruiz , Rocío Mosqueda-Peña , Ana Pérez-Ayala , Daniel Blázquez-Gamero

{"title":"Congenital cutaneous candidiasis associated with maternal peripartum candidemia","authors":"Mario Fernández-Ruiz , Rocío Mosqueda-Peña , Ana Pérez-Ayala , Daniel Blázquez-Gamero","doi":"10.1016/j.riam.2020.02.002","DOIUrl":"10.1016/j.riam.2020.02.002","url":null,"abstract":"<div><h3>Background</h3><p><span>Cutaneous congenital candidiasis (CCC) is a rare condition consisting of invasive fungal infection of the epidermis and </span>dermis that mostly affects preterm infants. Maternal vaginal candidiasis is present in half of the cases, although the occurrence of invasive candidiasis during pregnancy or peripartum period is exceptional.</p></div><div><h3>Case report</h3><p>We present the case of a full-term infant that was born by vacuum-assisted vaginal delivery to an apparently healthy 33 year-old woman with no history of intravenous drug use or vaginal candidiasis during pregnancy. The newborn showed a diffuse maculopapular rash with respiratory distress and bilateral interstitial lung infiltrates, requiring nasal continuous positive airway pressure support. Blood cultures obtained from the mother due to intrapartum fever yielded <span><em>Candida albicans</em></span>. Cultures of vaginal discharge and neonate skin also yielded <em>C. albicans</em><span> with the same in vitro susceptibly pattern. No alternative source for candidemia was identified. The clinical course after starting a systemic antifungal therapy was favorable in both the mother and the neonate, with clearance of candidemia and resolution of the skin lesions.</span></p></div><div><h3>Conclusions</h3><p>CCC must be considered in full-term newborns with maculopapular rash at birth or during the first days of life. The absence of alternative sources for bloodstream infection in the present case suggests a potential etiopathogenic relationship between CCC and maternal candidemia. It is reasonable to rule out postpartum candidemia when CCC is suspected.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2020.02.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38006394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Taking a look on fungi in cystic fibrosis: More questions than answers 看看真菌在囊性纤维化中的作用:问题多于答案

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-01-01 DOI: 10.1016/j.riam.2019.10.004

M. Teresa Martín-Gómez

{"title":"Taking a look on fungi in cystic fibrosis: More questions than answers","authors":"M. Teresa Martín-Gómez","doi":"10.1016/j.riam.2019.10.004","DOIUrl":"10.1016/j.riam.2019.10.004","url":null,"abstract":"<div><p>Cystic fibrosis (CF) is one of the most frequent recessive inherited diseases in western countries. Advances in medical care have led to a substantial increase in the life expectancy of CF patients. Survival beyond adolescence has permitted to see fungi not only as late colonizers, but also as potential pathogens responsible of allergic reactions and chronic infections related to lung function deterioration. The role of fungi, nevertheless, has been overlooked until recently. As a result, a number of questions on their epidemiology, clinical significance, or diagnosis, among others, remain unanswered. Besides more in depth studies about the extent of the deleterious effect of fungi on the CF host, new technologies may provide the key to understand its pathogenic role, its interaction with other microbial components of the respiratory microbiota, and should pave the way to define subsets of patients at risk who would benefit from specific therapy. This review is intended to provide a quick overview on what we know about the presence of fungi in the CF airway and its repercussion in the host, and to point out some of the many knowledge gaps needed to understand and advance in the management of fungi in the airway of CF subjects.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2019.10.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37534254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Colonización por Pneumocystis jirovecii en mujeres gestantes y recién nacidos en Lima, Perú 秘鲁利马孕妇和新生儿耶氏肺孢子虫的定植

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-01-01 DOI: 10.1016/j.riam.2019.11.001

Coralith Garcia , Theresa Ochoa , Edgar Neyra , Beatriz Bustamante , Carolina Ponce , Enrique J. Calderon , Sergio L. Vargas

{"title":"Colonización por Pneumocystis jirovecii en mujeres gestantes y recién nacidos en Lima, Perú","authors":"Coralith Garcia , Theresa Ochoa , Edgar Neyra , Beatriz Bustamante , Carolina Ponce , Enrique J. Calderon , Sergio L. Vargas","doi":"10.1016/j.riam.2019.11.001","DOIUrl":"10.1016/j.riam.2019.11.001","url":null,"abstract":"<div><h3>Background</h3><p><em>Pneumocystis</em> <em>jirovecii</em> primary infection occurs asymptomatically before 6 months of age, suggesting that the infection is acquired very early in life. Furthermore, <em>Pneumocystis</em> pneumonia has been described in newborns, which emphasizes the importance of studying <em>Pneumocystis</em> colonization in mother-infant pairs.</p></div><div><h3>Aims</h3><p>To evaluate the prevalence of <em>Pneumocystis</em> colonization among pregnant women and to determine the potential transplacental transmission.</p></div><div><h3>Methods</h3><p>A cross-sectional study was carried out on HIV-negative women over 18 years-old, and 37 or more weeks of pregnancy attending <em>Hospital Cayetano Heredia</em> Maternity unit during 2016-2017. Clinical and demographical information was collected on them and their newborns. Oropharyngeal washes, nasal swabs, and placenta samples were collected from women, as well as a nasopharyngeal aspirate and nasal swab from newborns. All respiratory samples were analysed by nested-PCR for the detection of <em>Pneumocystis</em>. Placenta samples from women with a positive PCR result in their respiratory samples were also analysed by nested-PCR.</p></div><div><h3>Results</h3><p>Of the 92 pregnant women included, five of them (5.43%) were colonized by <em>Pneumocystis</em>. <em>Pneumocystis</em> DNA was not found in any of the 87 available newborn samples or in the placentas of the five women who had a positive result by PCR in their upper respiratory samples.</p></div><div><h3>Conclusions</h3><p>It was found that 5.43% of the pregnant women were colonized by <em>Pneumocystis</em>, there was no evidence of any role of this colonization in the transmission to their newborns, since none of them tested positive for <em>Pneumocystis</em>.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2019.11.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37606801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Histoplasmosis en Argentina: serie de casos en niños [阿根廷组织胞浆菌病:儿童病例系列]。

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-01-01 DOI: 10.1016/j.riam.2019.10.005

Carla Voto , M. Guadalupe Pérez , Sandra Gómez , Carolina Epelbaum , Claudia Sarkis , Patricia Santos , Susana Carnovale , Cristina Canteros , Rosa Bologna

{"title":"Histoplasmosis en Argentina: serie de casos en niños","authors":"Carla Voto , M. Guadalupe Pérez , Sandra Gómez , Carolina Epelbaum , Claudia Sarkis , Patricia Santos , Susana Carnovale , Cristina Canteros , Rosa Bologna","doi":"10.1016/j.riam.2019.10.005","DOIUrl":"10.1016/j.riam.2019.10.005","url":null,"abstract":"<div><h3>Background</h3><p>Histoplasmosis is a fungal disease, endemic in South America, and seldom reported in paediatrics.</p></div><div><h3>Aims</h3><p>To report the epidemiology, clinical features and outcome of children diagnosed with histoplasmosis in an Argentinian Children's Hospital.</p></div><div><h3>Methods</h3><p>A retrospective and descriptive study was performed from January 2008 to December 2016 in Hospital de Pediatría ‘Prof. Dr. Juan Pedro Garrahan’. Patients under 18 years with clinical features, serological tests, cultures and/or histological findings compatible with histoplasmosis were included. Thirteen patients were selected (seven male and six female; mean age was 9 years with interquartile range 3.4-13); three children (23%) were from Buenos Aires province, three (23%) from Santa Fe province, and seven (54%) from other provinces.</p></div><div><h3>Results</h3><p>In ten cases (77%) the clinical form was disseminated, and it was pulmonary in three (23%). Eight cases (62%) suffered other comorbidities. Serological tests were positive in seven patients (54%), with positive cultures obtained in nine patients (69%). Histological findings compatible with histoplasmosis were found in 10 cases (77%). All patients received treatment with amphotericin B (liposomal formulation in seven cases, deoxycholate in six), with 10 patients continuing with oral itraconazole. Three patients (23%) died from causes unrelated to histoplasmosis.</p></div><div><h3>Conclusions</h3><p>The majority of children in the series had comorbidities and disseminated histoplasmosis. Mortality was not directly associated with histoplasmosis.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2019.10.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37512212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Fungal infections following treatment with monoclonal antibodies and other immunomodulatory therapies 单克隆抗体和其他免疫调节疗法治疗后的真菌感染

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-01-01 DOI: 10.1016/j.riam.2019.09.001

Francisco Javier Candel , Marina Peñuelas , Carolina Tabares , Carolina Garcia-Vidal , Mayra Matesanz , Miguel Salavert , Pilar Rivas , Javier Pemán

{"title":"Fungal infections following treatment with monoclonal antibodies and other immunomodulatory therapies","authors":"Francisco Javier Candel , Marina Peñuelas , Carolina Tabares , Carolina Garcia-Vidal , Mayra Matesanz , Miguel Salavert , Pilar Rivas , Javier Pemán","doi":"10.1016/j.riam.2019.09.001","DOIUrl":"10.1016/j.riam.2019.09.001","url":null,"abstract":"<div><p><span>Tumor necrosis factor (TNF) is a proinflammatory cytokine involved in a wide range of important physiologic processes and has a pathologic role in some diseases. TNF<span> antagonists (infliximab, adalimumab<span>, etanercept) are effective in treating inflammatory conditions. Antilymphocyte biological agents (rituximab, alemtuzumab), integrin antagonists (natalizumab, etrolizumab and vedolizumab), interleukin (IL)-17A blockers (secukinumab, ixekizumab) and IL-2 antagonists (daclizumab, basiliximab) are widely used after transplantation and for gastroenterological, rheumatological, dermatological, neurological and hematological disorders. Given the putative role of these host defense elements against bacterial, viral and fungal agents, the risk of infection during a treatment with these antagonists is a concern. Fungal infections, both opportunistic and endemic, have been associated with these biological therapies, but the causative relationship is unclear, especially among patients with poor control of their underlying disease or who are undergoing steroid therapy. Potential recipients of these drugs should be screened for latent endemic fungal infections. Cotrimoxazole prophylaxis could be useful for preventing </span></span></span><span><em>Pneumocystis jirovecii</em></span> infection in patients over 65 years of age who are taking TNF antagonists, antilymphocyte biological agents or who have lymphopenia and are undergoing concomitant steroid therapy. As with other immunosuppressant drugs, TNF antagonists and antilymphocyte antibodies should be discontinued for patients with active infectious disease.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2019.09.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37462564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12