Revista Iberoamericana De Micologia最新文献_第10页

Infección fúngica sinusal por Schizophyllum commune: a propósito de dos casos clínicos 常见裂叶菌鼻窦真菌感染:两例临床病例的综述

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2020.02.004

Belén Fernández-Caso , Arturo Manuel Fraile , Marta Soledad Rodríguez , Inmaculada Fernández , Buenaventura Buendía

{"title":"Infección fúngica sinusal por Schizophyllum commune: a propósito de dos casos clínicos","authors":"Belén Fernández-Caso , Arturo Manuel Fraile , Marta Soledad Rodríguez , Inmaculada Fernández , Buenaventura Buendía","doi":"10.1016/j.riam.2020.02.004","DOIUrl":"10.1016/j.riam.2020.02.004","url":null,"abstract":"<div><h3>Background</h3><p><em>Schizophyllum commune</em> is a basidiomycete fungus which is widely distributed in nature. Its role as responsible for disease in humans is not well known, partly due to its difficult identification. The incorporation of mass spectrometry techniques (MALDI-TOF) and molecular biology to the laboratories has allowed the description of a greater number of cases.</p></div><div><h3>Case report</h3><p>In this paper, we present two cases in which <em>S. commune</em> was identified as the causative agent of disease: in the first case an immunocompetent patient suffered from chronic rhinosinusitis, and in the second one a sphenoid sinus infection was diagnosed in an immunocompromised patient. In both cases, <em>S. commune</em> was isolated. Its identification was possible by means of MALDI-TOF and this was confirmed in both patients by amplification and sequencing of the ITS region.</p></div><div><h3>Conclusions</h3><p>In conclusion, <em>S. commune</em> should be considered a potential causative agent of fungal disease. Currently, MALDI-TOF and sequencing techniques are necessary for its identification.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":"37 2","pages":"Pages 65-67"},"PeriodicalIF":1.9,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2020.02.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37909114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Micosis pulmonares en pacientes con diabetes mellitus. Características clínicas y factores de riesgo 糖尿病患者肺真菌病。临床特征及危险因素

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2020.04.002

Alejandro Hernández-Solís , Alejandra Camerino Guerrero , Yesenia Colín Muñoz , Saret Bazán Cuervo , Raúl Cícero Sabido , Arturo Reding-Bernal

{"title":"Micosis pulmonares en pacientes con diabetes mellitus. Características clínicas y factores de riesgo","authors":"Alejandro Hernández-Solís , Alejandra Camerino Guerrero , Yesenia Colín Muñoz , Saret Bazán Cuervo , Raúl Cícero Sabido , Arturo Reding-Bernal","doi":"10.1016/j.riam.2020.04.002","DOIUrl":"10.1016/j.riam.2020.04.002","url":null,"abstract":"<div><h3>Background</h3><p>Diabetes mellitus is a public health problem in Mexico, and the trend of the disease is increasing. From 2000 to 2017, 7.32 million new cases were diagnosed, with pulmonary mycoses being one of the most serious complications.</p></div><div><h3>Aims</h3><p>To describe the frequency and the clinical characteristics of patients diagnosed with pulmonary mycoses, and to identify the risk factors associated with this entity.</p></div><div><h3>Methods</h3><p>Case–control study, paired by gender (1:1-3) and age (± 5 years), that analyzed patients with pulmonary mycosis (mucormycosis, histoplasmosis, coccidioidomycosis, blastomycosis, aspergillosis, cryptococcosis, paracoccidioidomycosis) and studied the risk factors present in each patient.</p></div><div><h3>Results</h3><p>From the 162 patients studied, 56 suffered pulmonary mycosis and 106 were controls. The median of the age was 51 and 50 years for the cases and for the controls, respectively. Multiple logistic regression analysis showed that patients with diabetes mellitus had an odds ratio of 8,3 <em>(p</em> < 0.001), and patients with a history of tuberculosis had an odds ratio of 8,8 <em>(p</em> < 0.001).</p></div><div><h3>Conclusions</h3><p>Our results show that 52% of the patients with pulmonary mycoses had a history of diabetes mellitus. Diabetes mellitus is a relevant risk factor for pulmonary mycoses, which are usually diagnosed in advanced stages and have a high mortality.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":"37 2","pages":"Pages 53-57"},"PeriodicalIF":1.9,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2020.04.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38113315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Actividad antifúngica de los enjuagues bucales frente a Candida albicans y Rhodotorula mucilaginosa: un estudio in vitro 漱口水对白色念珠菌和黏液红藻的抗真菌活性:一项体外研究

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2019.10.006

Rodrigo Alejandro Handschuh Briones , Evelyn Nicole Silva Arcos , Milton Urrutia , Patricio Godoy-Martínez

{"title":"Actividad antifúngica de los enjuagues bucales frente a Candida albicans y Rhodotorula mucilaginosa: un estudio in vitro","authors":"Rodrigo Alejandro Handschuh Briones , Evelyn Nicole Silva Arcos , Milton Urrutia , Patricio Godoy-Martínez","doi":"10.1016/j.riam.2019.10.006","DOIUrl":"10.1016/j.riam.2019.10.006","url":null,"abstract":"<div><h3>Background</h3><p><em>Candida albicans</em> and <em>Rhodotorula mucilaginosa</em> are yeasts of clinical importance in the oral cavity. In immunocompromised patients they can cause some pathologies that must be controlled with antimicrobials.</p></div><div><h3>Aims</h3><p>To evaluate and compare the antimicrobial efficacy of commercially available mouthrinses against strains of <em>C. albicans</em> and <em>R. mucilaginosa</em>.</p></div><div><h3>Methods</h3><p>The six mouthwashes studied <em>in vitro</em> were formulated (alone or in combination) with chlorhexidine (CHX) 0.12%, CHX 0.1%, CHX 0.05%, cetylpyridinium chloride (CPC) 0.075%, CPC 0.05%, and essential oils. Ten <em>C. albicans</em> and <em>R. mucilaginosa</em> isolates each were studied. The agar diffusion method (Mueller Hinton II), with incubation at 32°C was used to evaluate the antifungal activity.</p></div><div><h3>Results</h3><p>The results of this study indicate that mouthwashes with CHX 0.1%, CHX 0.12%, CHX 0.05% + CPC 0.05%, CHX 0.12% + CPC 0.05% and CPC 0.075% have an antifungal effect against <em>C. albicans</em> and <em>R. mucilaginosa</em>. CHX 0.1% led to the broadest inhibition zone for <em>C. albicans</em> and <em>R. mucilaginosa</em> (25.65±2.39mm and 40.05±3.31mm). Essential oils did not show any antifungal activity. Statistical analysis showed no statistical difference between mouth rinses CHX 0.1%, CHX 0.12% and CHX 0.12% + CPC 0.05% (<em>p</em>  <!-->0.0001) against <em>C. albicans</em> and <em>R. mucilaginosa</em>.</p></div><div><h3>Conclusions</h3><p>Mouthwashes with CHX showed higher antifungal activity against <em>C. albicans</em> and <em>R. mucilaginosa</em> than other mouthwashes studied.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":"37 2","pages":"Pages 47-52"},"PeriodicalIF":1.9,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2019.10.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38198998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tsunamis and changes in the etiology of the canine and feline cryptococcosis 海啸和犬猫隐球菌病病因学的变化

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2019.12.002

F. Javier Cabañes

引用次数: 0

Rhodotorula dairenensis fungemia in a patient with cancer 癌症患者的戴氏红酵母菌血症

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2020.03.006

Fernando Cobo , Óscar Zaragoza , José María Navarro-Marí

引用次数: 2

Diversity and adaptation within the genus Malassezia: Bats already have their species 马拉色属的多样性和适应性:蝙蝠已经有了自己的物种

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2019.12.001

F. Javier Cabañes

引用次数: 2

Micosis cutánea por Curvularia pallescens en un paciente trasplantado pulmonar: primer caso descrito en España 肺移植患者的皮肤真菌病:西班牙首次描述的病例

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2020.03.005

Sheila Requena López , Patricia Morales del Burgo , Santiago Gómez Díez , Jose Antonio Boga , Teresa Peláez García de la Rasilla

{"title":"Micosis cutánea por Curvularia pallescens en un paciente trasplantado pulmonar: primer caso descrito en España","authors":"Sheila Requena López , Patricia Morales del Burgo , Santiago Gómez Díez , Jose Antonio Boga , Teresa Peláez García de la Rasilla","doi":"10.1016/j.riam.2020.03.005","DOIUrl":"10.1016/j.riam.2020.03.005","url":null,"abstract":"<div><h3>Background</h3><p><em>Curvularia</em> is a filamentous dematiaceous fungus increasingly recognized as a pathogen in immunocompromised patients. The most common clinical entities associated with this fungus are allergic sinusitis, cutaneous infection and keratitis. In this article, a report on the first clinical case of <em>Curvularia pallescens</em> cutaneous infection in Spain and its treatment is described.</p></div><div><h3>Case report</h3><p>A 68 year-old man with a history of lung transplantation presented to Dermatology Unit due to a skin lesion in the knee that had been evolving for 6 months. A skin biopsy was performed for its study. In the histopathological study, an intense and non-specific inflammatory reaction in the dermis was observed, and with Grocott stain and periodic acid Schiff abundant septate hyphae and spores were found in the dermis. The culture of the sample revealed a filamentous fungus whose microscopic examination allowed to identify the genus as <em>Curvularia</em>. Using MALDI-TOF mass spectrometry and molecular identification, the fungus was finally identified as <em>Curvularia pallescens.</em> The patient underwent surgical resection of the lesion and was treated with posaconazole, evolving favorably.</p></div><div><h3>Conclusions</h3><p>The species of <em>Curvularia</em> should be considered causal agents of fungal skin infections in immunosuppressed patients. This clinical case, which showed good clinical response after surgical resection and treatment with posaconazole, is the first described in Spain due to this species.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":"37 2","pages":"Pages 58-62"},"PeriodicalIF":1.9,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2020.03.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38077561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fungal co-infection in COVID-19 patients: Should we be concerned? COVID-19患者的真菌合并感染:我们应该关注吗?

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2020.07.001

Javier Pemán , Alba Ruiz-Gaitán , Carolina García-Vidal , Miguel Salavert , Paula Ramírez , Francesc Puchades , Marta García-Hita , Ana Alastruey-Izquierdo , Guillermo Quindós

{"title":"Fungal co-infection in COVID-19 patients: Should we be concerned?","authors":"Javier Pemán , Alba Ruiz-Gaitán , Carolina García-Vidal , Miguel Salavert , Paula Ramírez , Francesc Puchades , Marta García-Hita , Ana Alastruey-Izquierdo , Guillermo Quindós","doi":"10.1016/j.riam.2020.07.001","DOIUrl":"10.1016/j.riam.2020.07.001","url":null,"abstract":"<div><p>Critically ill COVID-19 patients have higher pro-inflammatory (IL-1, IL-2, IL-6, tumor necrosis alpha) and anti-inflammatory (IL-4, IL-10) cytokine levels, less CD<sub>4</sub> interferon-gamma expression, and fewer CD<sub>4</sub> and CD<sub>8</sub> cells. This severe clinical situation increases the risk of serious fungal infections, such as invasive pulmonary aspergillosis, invasive candidiasis or <em>Pneumocystis jirovecii</em> pneumonia. However, few studies have investigated fungal coinfections in this population. We describe an update on published reports on fungal coinfections and our personal experience in three Spanish hospitals. We can conclude that despite the serious disease caused by SARS-CoV-2 in many patients, the scarcity of invasive mycoses is probably due to the few bronchoscopies and necropsies performed in these patients because of the high risk in aerosol generation. However, the presence of fungal markers in clinically relevant specimens, with the exception of bronchopulmonary colonization by <em>Candida</em>, should make it advisable to early implement antifungal therapy.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":"37 2","pages":"Pages 41-46"},"PeriodicalIF":1.9,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2020.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38474990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 124

Congenital cutaneous candidiasis associated with maternal peripartum candidemia 先天性皮肤念珠菌病与母体围产期念珠菌血症相关

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-04-01 DOI: 10.1016/j.riam.2020.02.002

Mario Fernández-Ruiz , Rocío Mosqueda-Peña , Ana Pérez-Ayala , Daniel Blázquez-Gamero

{"title":"Congenital cutaneous candidiasis associated with maternal peripartum candidemia","authors":"Mario Fernández-Ruiz , Rocío Mosqueda-Peña , Ana Pérez-Ayala , Daniel Blázquez-Gamero","doi":"10.1016/j.riam.2020.02.002","DOIUrl":"10.1016/j.riam.2020.02.002","url":null,"abstract":"<div><h3>Background</h3><p><span>Cutaneous congenital candidiasis (CCC) is a rare condition consisting of invasive fungal infection of the epidermis and </span>dermis that mostly affects preterm infants. Maternal vaginal candidiasis is present in half of the cases, although the occurrence of invasive candidiasis during pregnancy or peripartum period is exceptional.</p></div><div><h3>Case report</h3><p>We present the case of a full-term infant that was born by vacuum-assisted vaginal delivery to an apparently healthy 33 year-old woman with no history of intravenous drug use or vaginal candidiasis during pregnancy. The newborn showed a diffuse maculopapular rash with respiratory distress and bilateral interstitial lung infiltrates, requiring nasal continuous positive airway pressure support. Blood cultures obtained from the mother due to intrapartum fever yielded <span><em>Candida albicans</em></span>. Cultures of vaginal discharge and neonate skin also yielded <em>C. albicans</em><span> with the same in vitro susceptibly pattern. No alternative source for candidemia was identified. The clinical course after starting a systemic antifungal therapy was favorable in both the mother and the neonate, with clearance of candidemia and resolution of the skin lesions.</span></p></div><div><h3>Conclusions</h3><p>CCC must be considered in full-term newborns with maculopapular rash at birth or during the first days of life. The absence of alternative sources for bloodstream infection in the present case suggests a potential etiopathogenic relationship between CCC and maternal candidemia. It is reasonable to rule out postpartum candidemia when CCC is suspected.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":"37 2","pages":"Pages 68-71"},"PeriodicalIF":1.9,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2020.02.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38006394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Taking a look on fungi in cystic fibrosis: More questions than answers 看看真菌在囊性纤维化中的作用:问题多于答案

IF 1.9 4区生物学

Revista Iberoamericana De Micologia Pub Date : 2020-01-01 DOI: 10.1016/j.riam.2019.10.004

M. Teresa Martín-Gómez

{"title":"Taking a look on fungi in cystic fibrosis: More questions than answers","authors":"M. Teresa Martín-Gómez","doi":"10.1016/j.riam.2019.10.004","DOIUrl":"10.1016/j.riam.2019.10.004","url":null,"abstract":"<div><p>Cystic fibrosis (CF) is one of the most frequent recessive inherited diseases in western countries. Advances in medical care have led to a substantial increase in the life expectancy of CF patients. Survival beyond adolescence has permitted to see fungi not only as late colonizers, but also as potential pathogens responsible of allergic reactions and chronic infections related to lung function deterioration. The role of fungi, nevertheless, has been overlooked until recently. As a result, a number of questions on their epidemiology, clinical significance, or diagnosis, among others, remain unanswered. Besides more in depth studies about the extent of the deleterious effect of fungi on the CF host, new technologies may provide the key to understand its pathogenic role, its interaction with other microbial components of the respiratory microbiota, and should pave the way to define subsets of patients at risk who would benefit from specific therapy. This review is intended to provide a quick overview on what we know about the presence of fungi in the CF airway and its repercussion in the host, and to point out some of the many knowledge gaps needed to understand and advance in the management of fungi in the airway of CF subjects.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":"37 1","pages":"Pages 17-23"},"PeriodicalIF":1.9,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.riam.2019.10.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37534254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6