Revista Espanola De Quimioterapia最新文献_第6页

[Macrolide-resistant Mycoplasma pneumoniae: Do we know the situation in Europe?] 耐大环内酯肺炎支原体:我们了解欧洲的情况吗?］

IF 1.9 4区医学

Revista Espanola De Quimioterapia Pub Date : 2023-06-01 DOI: 10.37201/req/118.2022

A I Álvaro Varela, A Aguinaga Pérez, A Navascués Ortega, J Castilla Catalán, C Ezpeleta Baquedano

引用次数: 0

[First outbreak of Clostridioides difficile ribotype 027 in the Canary Islands]. [加那利群岛首次爆发艰难梭菌027型核糖型]。

IF 1.9 4区医学

Revista Espanola De Quimioterapia Pub Date : 2023-06-01 DOI: 10.37201/req/105.2022

M Aroca-Ferri, T Tosco-Núñez, M Peñate-Bolaños, J Molina-Cabrillana, M Ojeda-Vargas

引用次数: 0

[Antibiotic resistance changes in episodes of symptomatic bacteriospermia: development in a health area of southeast Spain]. [症状性细菌精子症发作的抗生素耐药性变化:西班牙东南部一个卫生地区的发展]。

IF 1.9 4区医学

Revista Espanola De Quimioterapia Pub Date : 2023-06-01 DOI: 10.37201/req/117.2022

R Mendoza-Rodríguez, I Hernández-Chico, M Expósito-Ruiz, J M Navarro-Marí, J Gutiérrez-Fernández, A Rosales-Castillo

{"title":"[Antibiotic resistance changes in episodes of symptomatic bacteriospermia: development in a health area of southeast Spain].","authors":"R Mendoza-Rodríguez, I Hernández-Chico, M Expósito-Ruiz, J M Navarro-Marí, J Gutiérrez-Fernández, A Rosales-Castillo","doi":"10.37201/req/117.2022","DOIUrl":"https://doi.org/10.37201/req/117.2022","url":null,"abstract":"Objective: Chronic bacterial prostatitis (CBP) is an entity of difficult clinical diagnosis and treatment, being the microbiological study of semen the main diagnostic test. This study aimed to determine the etiology and antibiotic resistance in patients with symptomatic bacteriospermia (SBP) in our environment.Methods: A cross-sectional and retrospective descriptive study has been carried out from a Regional Hospital of the Spanish Southeast. The participants were patients assisted in the consultations of the Hospital with clinic compatible with CBP, between 2016 and 2021. The interventions were collection and analysis of the results derived from the microbiological study of the semen sample. The main determinations were the etiology and rate of antibiotic resistance of BPS episodes are analyzed.Results: The main isolated microorganism is Enterococcus faecalis (34.89%), followed by Ureaplasma spp. (13.74%) and Escherichia coli (10.98%). The rate of antibiotic resistance of E. faecalis to quinolones (11%) is lower than previous studies, while for E. coli it has been higher (35%). The low rate of resistance shown by E. faecalis and E. coli to fosfomycin and nitrofurantoin stands out.Conclusions: In the SBP, gram-positive and atypical bacteria are established as the main causative agents of this entity. This forces us to rethink the therapeutic strategy used, which will avoid the increase in antibiotic resistance, recurrences, and chronicity of this pathology.","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3b/71/revespquimioter-36-275.PMC10238802.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9623848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Status of Herpes Zoster and Herpes Zoster Vaccines in 2023: A position paper. 2023年带状疱疹和带状疱疹疫苗的现状:一份立场文件。

IF 1.9 4区医学

Revista Espanola De Quimioterapia Pub Date : 2023-06-01 DOI: 10.37201/req/004.2023

J M Molero García, S Moreno Guillén, F J Rodríguez-Artalejo, J Ruiz-Galiana, R Cantón, P De Lucas Ramos, A García-Botella, A García-Lledó, T Hernández-Sampelayo, J Gómez-Pavón, J González Del Castillo, M C Martín-Delgado, F J Martín Sánchez, M Martínez-Sellés, E Bouza

{"title":"Status of Herpes Zoster and Herpes Zoster Vaccines in 2023: A position paper.","authors":"J M Molero García, S Moreno Guillén, F J Rodríguez-Artalejo, J Ruiz-Galiana, R Cantón, P De Lucas Ramos, A García-Botella, A García-Lledó, T Hernández-Sampelayo, J Gómez-Pavón, J González Del Castillo, M C Martín-Delgado, F J Martín Sánchez, M Martínez-Sellés, E Bouza","doi":"10.37201/req/004.2023","DOIUrl":"https://doi.org/10.37201/req/004.2023","url":null,"abstract":"Herpes zoster infection (HZ) is an important public health problem due to its high incidence and frequent complications, especially post-herpetic neuropathy . The incidence of HZ increases with age and is more frequent in immunocompromised patients. It is estimated that at least 60,000 people develop HZ each year in Spain. The usual forms of HZ are so clinically characteristic that they do not usually require microbiological confirmation, which is reserved for cases without cutaneous manifestations or with atypical presentation. There are currently two vaccines approved by the regulatory agencies and marketed in Spain to prevent the onset of HZ and its complications. The first (Zostavax®) was marketed by the company MSD and licensed in Europe in 2006 and is a live attenuated virus vaccine that is administered in a single dose, while the second (Shingrix®) is a recombinant vaccine, marketed in 2017 and requires two doses. While the former cannot be administered to immunocompromised persons, the latter can be prescribed to any group of adults. The criteria for the indication and financing of these vaccines have not been uniform in the various autonomous communities of Spain. These and other aspects of HZ have been discussed by a group of experts from the Illustrious Official College of Physicians of Madrid (ICOMEM) whose criteria and opinions are included in this paper.","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/78/64/revespquimioter-36-223.PMC10238794.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9561760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Epidemiology and prevalence of mutations associated with resistance to macrolides and fluoroquinolones in Mycoplasma genitalium in a tertiary hospital from Madrid, Spain. 西班牙马德里某三级医院生殖支原体大环内酯类药物和氟喹诺酮类药物耐药相关突变的流行病学和流行率

IF 1.9 4区医学

Revista Espanola De Quimioterapia Pub Date : 2023-06-01 DOI: 10.37201/req/123.2022

A Maldonado-Barrueco, M Rodríguez-Ayala, D Grandioso-Vas, P García-Clemente, G V Guedez-López, J García-Rodríguez, I Quiles-Melero

{"title":"Epidemiology and prevalence of mutations associated with resistance to macrolides and fluoroquinolones in Mycoplasma genitalium in a tertiary hospital from Madrid, Spain.","authors":"A Maldonado-Barrueco, M Rodríguez-Ayala, D Grandioso-Vas, P García-Clemente, G V Guedez-López, J García-Rodríguez, I Quiles-Melero","doi":"10.37201/req/123.2022","DOIUrl":"https://doi.org/10.37201/req/123.2022","url":null,"abstract":"Objective: Mycoplasma genitalium causes persistent sexually transmitted infections. The aims of this study were to estimate the prevalence of resistances to macrolides and fluoroquinolones in M. genitalium and the sexually transmitted coinfections in patients at Hospital Universitario La Paz (Madrid, Spain).Methods: Patients attended between January and October 2021 were studied. Screening for sexually transmitted pathogens and detection of 23S rRNA and parC genes mutations were performed by real-time PCR (Allplex,SeegeneTM).Results: A total of 1,518 females and 1,136 males were studied. The prevalence of M. genitalium was 2.1%. The macrolides resistance rate was 51.8%. The mutations found were A2059G, A2058T and A2058G. The rate of resistance to fluoroquinolones was 17.8% being the G248T mutation (S83I) the most frequent. Seven males had some sexual transmitted coinfection.Conclusions: Although the percentage of M. genitalium infections is low, the high rate of resistance to macrolides makes it necessary to revise the protocols for diagnosis and empirical treatment of sexually transmitted infections. The use of fluoroquinolones is appropriate after screening of macrolide resistance profile.","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f9/44/revespquimioter-36-310.PMC10238788.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9562247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Clostridium perfringens abscess in parenteral drug users]. [肠外吸毒者的产气荚膜梭菌脓肿]。

IF 1.9 4区医学

Revista Espanola De Quimioterapia Pub Date : 2023-06-01 DOI: 10.37201/req/103.2022

A Maldonado-Barrueco, D Grandioso-Vas, J García-Rodríguez, I Quiles-Melero

引用次数: 0

Response to "The importance of an early gastroenteritis diagnosis to discard MIS-C during SARS-CoV-2 pandemic". 对“SARS-CoV-2大流行期间早期胃肠炎诊断对丢弃MIS-C的重要性”的回应。

IF 1.9 4区医学

Revista Espanola De Quimioterapia Pub Date : 2023-06-01 DOI: 10.37201/req/120.2022

P Rodríguez-Lorenzo, M Arias-Temprano, A Méndez-Sánchez, C Pérez-Méndez

{"title":"Response to \"The importance of an early gastroenteritis diagnosis to discard MIS-C during SARS-CoV-2 pandemic\".","authors":"P Rodríguez-Lorenzo, M Arias-Temprano, A Méndez-Sánchez, C Pérez-Méndez","doi":"10.37201/req/120.2022","DOIUrl":"https://doi.org/10.37201/req/120.2022","url":null,"abstract":"Rev Esp Quimioter 2023;36(3): 322-324 322 Results are shown in Table 1. As expected, more cases of Campylobacter infection were diagnosed in the first period while more laboratory studies were performed in the second period (47.2% vs 14.9%), probably as a reflection of the fear of missing a possible diagnosis of MIS-C in the pandemic era. No cases showing both elevated C-reactive protein and profound lymphopenia were observed among the 74 children seen in the prepandemic period, while four (11.1% of the total cases and 30.6% of those in whom laboratory tests were performed) were found in the pandemic era. Evidence of SARS-CoV-2 exposure in the previous weeks was confirmed in three of these cases and infection was documented in one child, who was initially diagnosed as possible MIS-C and treated with intravenous gammaglobulin and corticosteroids for one day; treatment was suspended when the diagnosis of Campylobacter infection was confirmed. Clinical characteristics and laboratory findings of these four patients are shown in table 2. Our results raise the question of whether Campylobacter infection alone can be accountable for these laboratory findings and if a positive stool test can safely rule out a diagnosis of MIS-C or a short observation period in the hospital would be prudent, as children with MIS-C may develop additional organ system involvement over the course of admission [4]. Lymphopenia has been previously described in up to 11% of patients with Campylobacter infection returning from the tropics, Response to “The importance of an early gastroenteritis diagnosis to discard MIS-C during SARS-CoV-2 pandemic”","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fa/92/revespquimioter-36-322.PMC10238798.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9942696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacteremia caused by Eikenella corrodens in a patient with pelvic inflammatory disease. 盆腔炎患者由艾肯氏菌引起的菌血症腐蚀。

IF 1.9 4区医学

Revista Espanola De Quimioterapia Pub Date : 2023-06-01 DOI: 10.37201/req/128.2022

M P Roche Matheus, D Fernández Vecilla, M J Urrutikoetxea Gutiérrez, F E Calvo Muro, G Iglesias Hidalgo, J L Díaz de Tuesta Del Arco

引用次数: 0

[Shigellosis attended in the emergency department of a regional hospital in southeastern Spain: from their presence to multiresistance]. [志贺氏菌病在西班牙东南部一家地区医院的急诊科就诊:从其存在到多重耐药性]。

IF 1.9 4区医学

Revista Espanola De Quimioterapia Pub Date : 2023-06-01 DOI: 10.37201/req/121.2022

E Rodríguez-Guerrero, S Herrera-León, E Gómez-Vicente, J M Navarro-Marí, J Gutiérrez-Fernández

{"title":"[Shigellosis attended in the emergency department of a regional hospital in southeastern Spain: from their presence to multiresistance].","authors":"E Rodríguez-Guerrero, S Herrera-León, E Gómez-Vicente, J M Navarro-Marí, J Gutiérrez-Fernández","doi":"10.37201/req/121.2022","DOIUrl":"https://doi.org/10.37201/req/121.2022","url":null,"abstract":"Objective: In the bacterial etiology of severe acute infectious diarrhea, except that caused by Clostridioides difficile, most of them have an invasive character and antibiotic treatment will be necessary in specific situations. Shigella is a classic pathogen, in which it is crucial to know the sensitivity to different classic and alternative antimicrobials. The objective of this work was to analyze the presence of shigellosis and the rate of antibiotic resistance.Methods: A descriptive-retrospective study of the reports of shigellosis of stool cultures issued between January 2016 and April 2022 was conducted.Results: A total of 34 episodes (16 -47.1%- by Shigella sonnei) were observed, as of 2018. There were only 2 pediatric cases. The overall resistance rate to azithromycin, trimethoprim-sulfamethoxazole and ciprofloxacin was 52.9%, 64.7% and 44.1%, respectively. 26.5% were resistant to the 3 groups of antibiotics. There was a higher rate of resistance for S. sonnei. The emergence of resistance to cephalosporins in recent years stands out. Episodes of multidrug-resistant shigellosis were detected between 2020 (1 by S. flexneri) and 2022 (4 by S. sonnei).Conclusions: The episodes of shigellosis are emerging in our environment with a higher rate of multi-resistance. In this context, current empirical treatments for acute enteroinvasive enteritis are at risk of failure, if necessary.","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/93/42/revespquimioter-36-282.PMC10238789.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9574470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Economic burden of skin and skin structure infections due to Gram-positive bacteria in patients on hospital at home-based outpatient parenteral antibiotic therapy (OPAT). 家庭门诊静脉注射抗生素治疗(OPAT)患者革兰氏阳性菌引起的皮肤和皮肤结构感染的经济负担

IF 1.9 4区医学

Revista Espanola De Quimioterapia Pub Date : 2023-06-01 DOI: 10.37201/req/134.2022

M Mirón-Rubio, J J Parra Jordán, V J González Ramallo, A Mujal Martínez, J Fernández Muixí, M Iglesias Gallego, M C Lucas Núñez, E Rodado Alabau, S Vidal Perez-Campoamor, E Uría

{"title":"Economic burden of skin and skin structure infections due to Gram-positive bacteria in patients on hospital at home-based outpatient parenteral antibiotic therapy (OPAT).","authors":"M Mirón-Rubio, J J Parra Jordán, V J González Ramallo, A Mujal Martínez, J Fernández Muixí, M Iglesias Gallego, M C Lucas Núñez, E Rodado Alabau, S Vidal Perez-Campoamor, E Uría","doi":"10.37201/req/134.2022","DOIUrl":"https://doi.org/10.37201/req/134.2022","url":null,"abstract":"Objective: To describe and quantify resource use and direct health costs associated with skin and skin structure infections (SSSIs) caused by Gram-positive bacteria in adults receiving outpatient parenteral antimicrobial therapy (OPAT), administered by Hospital at Home units (HaH) in Spain.Methods: Observational, multicenter, retrospective study. We included patients of both sexes included in the HaH-based OPAT Registry during 2011 to 2017 who were hospitalized due to SSSIs caused by Gram-positive bacteria. Resource use included home visits (nurses and physician), emergency room visits, conventional hospitalization stay, HaH stay and antibiotic treatment. Costs were quantified by multiplying the natural units of the resources by the corresponding unit cost. All costs were updated to 2019 euros.Results: We included 194 episodes in 189 patients from 24 Spanish hospitals. The most frequent main diagnoses were cellulitis (26.8%) and surgical wound infection (24.2%), and 94% of episodes resulted in clinical improvement or cure after treatment. The median HaH stay was 13 days (interquartile range [IR]:8-22.7), and the conventional hospitalization stay was 5 days (IR: 1-10.7). The mean total cost attributable to the complete infectious process was €7,326 (95% confidence interval: €6,316-€8,416).Conclusions: Our results suggest that OPAT administered by HaH is a safe and efficient alternative for the management of these infections and could lead to lower costs compared with hospital admission.","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/40/3d/revespquimioter-36-291.PMC10238797.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9574959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1