{"title":"Pulmonary nocardiosis after covid-19 infection: case report and literature review.","authors":"J Ortiz, F Jover, V Ortiz de la Tabla, E Delgado","doi":"10.37201/req/132.2022","DOIUrl":"10.37201/req/132.2022","url":null,"abstract":"In one review of 1050 cases [5] main clinical presentations of nocardiosis were systemic (32 %); pulmonary (only) 39 %; CNS (only) 9 %, cutaneous or lymphocutaneous (8 %) and single site extrapulmonary (egg, eyes, bone) 12 %. The onset of pulmonary nocardiosis may be acute, subacute, or chronic and is not distinguished by any specific signs or symptoms. Fever, night sweats, fatigue, anorexia, weight loss, dyspnea, cough, hemoptysis, and pleuritic chest pain have all been described.","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/d9/revespquimioter-36-421.PMC10336311.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9847779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Julián-Jiménez, R Rubio-Díaz, J González Del Castillo, E J García-Lamberechts, I Huarte Sanz, C Navarro Bustos, F J Candel, P Angel de Santos, R Alonso Avilés
{"title":"[Ability of qSOFA1-lactate to predict 30-day mortality in patients seen for infection in the Emergency Department].","authors":"A Julián-Jiménez, R Rubio-Díaz, J González Del Castillo, E J García-Lamberechts, I Huarte Sanz, C Navarro Bustos, F J Candel, P Angel de Santos, R Alonso Avilés","doi":"10.37201/req/008.2023","DOIUrl":"https://doi.org/10.37201/req/008.2023","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate lactate and the Quick Sepsis-Related Organ Failure Assessment (qSOFA) and compare their ability to predict 30-day mortality in patients treated for infection in emergency departments (ED).</p><p><strong>Methods: </strong>Prospective multicenter observational cohort study. We enrolled a convenience sample of patients aged 18 years or older attended in 71 Spanish ED from October 1, 2019, to March 31, 2020. Each model's predictive power was analyzed with the area under the receiver operating characteristic curve (AUC), and its values of sensitivity (Se), specificity (Sp), positive predictive value (PPV) and negative (NPV).</p><p><strong>Results: </strong>A total of 4439 patients with a mean (SD) age of 18 years were studied; 2648 (59.7%) were men and 459 (10.3%) died within 30 days. For 30-day mortality, the AUC-COR obtained with the qSOFA = 1 model plus 2 mmol/l lactate was 0.66 (95% CI, 0.63-0.69) with Se: 68%, Es: 70% and NPV:92%, while qSOFA = 1 obtained AUC-COR of 0.52 (95% CI, 0.49-0.55) with a Se:42%, Es:64% and NPV:90%.</p><p><strong>Conclusions: </strong>To predict 30-day mortality in patients presenting to the ED due to an episode of infection, the qSOFA =1 + lactate≥2 mmol/L model significantly improves the predictive power achieved individually by qSOFA1 and becomes very similar to qSOFA≥2.</p>","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/c1/revespquimioter-36-408.PMC10336320.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9789742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I Alejo-Cancho, A Gual-de-Torrella, R Vielba Postigo, I Perez Abraguin, L Redondo Farias, M J Lopez de Goikoetxea
{"title":"[Solobacterium moorei bacteriemia in a patient with sinusitis].","authors":"I Alejo-Cancho, A Gual-de-Torrella, R Vielba Postigo, I Perez Abraguin, L Redondo Farias, M J Lopez de Goikoetxea","doi":"10.37201/req/141.2022","DOIUrl":"10.37201/req/141.2022","url":null,"abstract":"","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b0/21/revespquimioter-36-432.PMC10336307.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10151774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Mormeneo Bayo, A Bellés Bellés, I Prats Sánchez, E López González, J Aramburu Arnuelos, A Bernet Sánchez, M García González
{"title":"Fungal corneal abscess caused by Exophiala dermatitidis.","authors":"S Mormeneo Bayo, A Bellés Bellés, I Prats Sánchez, E López González, J Aramburu Arnuelos, A Bernet Sánchez, M García González","doi":"10.37201/req/133.2022","DOIUrl":"10.37201/req/133.2022","url":null,"abstract":"Rev Esp Quimioter 2023;36(4): 425-426 425 Antifungal susceptibility testing was performed by microdilution (Sensititre YeastOne, Thermo Fisher). The minimum inhibitory concentrations (MIC) of amphotericin B (0.50 mg/L), itraconazole (0.12 mg/L), voriconazole (0.03 mg/L), and posaconazole (0.03 mg/L) against the pathogenic strain were found to be low. However, MIC of fluconazole (8 mg/L), micafungin (>8 mg/L), caspofungin (>8 mg/L) and anidulafungin (>8 mg/L) were high. Based on these results, voriconazole eye drops for two months and oral voriconazole during three weeks were administered with good clinical evolution.","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7b/90/revespquimioter-36-425.PMC10336319.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9793972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Alonso Álvarez, E Sánchez Vidal, L Ramos Merino, D Sousa Regueiro, J Serrano Areba, E Míguez Rey, P Llinares Modéjar
{"title":"Use of ceftaroline in complex central nervous system infections.","authors":"A Alonso Álvarez, E Sánchez Vidal, L Ramos Merino, D Sousa Regueiro, J Serrano Areba, E Míguez Rey, P Llinares Modéjar","doi":"10.37201/req/143.2022","DOIUrl":"10.37201/req/143.2022","url":null,"abstract":"","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bc/c1/revespquimioter-36-434.PMC10336313.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9792256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C García-Rivera, I Escribano, E Merino, J C Rodriguez
{"title":"[Concordance between GeneXpert and Life Real Detection Kit in the diagnosis of acute respiratory infections].","authors":"C García-Rivera, I Escribano, E Merino, J C Rodriguez","doi":"10.37201/req/136.2022","DOIUrl":"10.37201/req/136.2022","url":null,"abstract":"","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/80/8b/revespquimioter-36-427.PMC10336314.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9791582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F J Candel, M Salavert, D Lorite Mingot, M Manzano Crespo, P Pérez Portero, R Cuervo Pinto
{"title":"Reduction in the risk of progression of solid organ transplant recipients infected by SARS-CoV-2 treated with monoclonal antibodies.","authors":"F J Candel, M Salavert, D Lorite Mingot, M Manzano Crespo, P Pérez Portero, R Cuervo Pinto","doi":"10.37201/req/023.2023","DOIUrl":"10.37201/req/023.2023","url":null,"abstract":"<p><p>Recipients of solid organ transplants (SOT) are at higher risk of infection by SARS-CoV-2 virus especially due to chronic immunosuppression therapy and frequent multiple comorbid conditions. COVID-19 is a potentially life-threatening disease in SOT recipients, with an increased likelihood of progressing to severe disease, with the need of hospitalization, admission to the intensive care unit (ICU) and mechanical ventilatory support. This article presents an updated review of different aspects related to the outcome of COVID-19 in SOT recipients. In nvaccinated SOT recipients, COVID-19 is associated with a high mortality rate, in-patient care and ICU admission, and impaired graft function or rejection in severe disease. In vaccinated SOT recipients even after full vaccination, there is a reduction of the risk of mortality, but the course of COVID-19 may continue to be severe, influenced by the time from transplant, the net state of immunosuppression and having suffered graft rejection or dysfunction. SOT recipients develop lower immunity from mRNA vaccines with suboptimal response. Treatment with mAbs provides favorable outcomes in non-hospitalized SOT recipients at high risk for severe disease, with lower rates of hospitalization, emergency department visits, ICU care, progression to severe disease, and death. However, broad vaccination and therapeutic options are required, particularly in light of the tendency of the SARS-CoV-2 virus to adapt and evade both natural and vaccine-induced immunity.</p>","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/34/fd/revespquimioter-36-380.PMC10336315.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9782065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Fernández Vecilla, M P Roche Matheus, G Iglesias Hidalgo, E Ugalde Zárraga, M J Unzaga Barañano, J L Díaz de Tuesta Del Arco
{"title":"Two cases of Prevotella oris causing serious pleuropulmonary infections.","authors":"D Fernández Vecilla, M P Roche Matheus, G Iglesias Hidalgo, E Ugalde Zárraga, M J Unzaga Barañano, J L Díaz de Tuesta Del Arco","doi":"10.37201/req/001.2023","DOIUrl":"10.37201/req/001.2023","url":null,"abstract":"Rev Esp Quimioter 2023;36(4): 439-441 439 Prevotella oris was identified by 16S rRNA gene sequencing of bronchial brushing and bronchoalveolar lavage samples with an homology percentage of 99.50% and 99.82%, respectively. The second sequence was registered in GenBank with accession number OP601405. After switching to IV 1 g/8 h cefotaxime and 260 mg/6 h vancomycin, the patient improved until resolution of the infection 18 days after admission (Figure 1C).","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/95/72/revespquimioter-36-439.PMC10336306.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9796285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Sánchez Fabra, T Herrero Jordán, A Alda Lozano, V Duro Suárez, N Saura Blasco, I Torres Courchoud
{"title":"[Management of COVID-19 pandemic in hospital at home in two regional Spanish hospitals. what it meant, who we cared for, who died and how assistance has evolved over time].","authors":"D Sánchez Fabra, T Herrero Jordán, A Alda Lozano, V Duro Suárez, N Saura Blasco, I Torres Courchoud","doi":"10.37201/req/138.2022","DOIUrl":"https://doi.org/10.37201/req/138.2022","url":null,"abstract":"<p><strong>Objective: </strong>Home Hospitalization (HH) is an alternative hospitalization modality that can be very useful in times of health stress such as the COVID-19 pandemic. This paper includes the management of patients admitted with COVID-19 in HH in two county spanish hospitals for two years.</p><p><strong>Methods: </strong>A descriptive, observational and retrospective study of all patients admitted at HH with a diagnosis of COVID-19 disease was carried out. Subsequently, further analysis was carried out to characterize the patients who died in HH or 30 days after discharge and another to compare the management between the first phase of the study (2020) and the second one (2021 and part of 2022).</p><p><strong>Results: </strong>A total of 167 patients were recruited. A 52.1% moved to watch that the recovery continued compared to 40.7% in which it was done to watch that they did not worsen. The patients who died in HAD were older (mean 87.5 years), more comorbid and more likely to have do-not resucitate orders (DNR) in case of cardiac arrest (85%). In the second phase of the study, older patients, more comorbid patients and with a greater degree of DNR orders were admitted than those admitted throughout 2020.</p><p><strong>Conclusions: </strong>HAD is a useful resource to increase the resilience of health systems in cases of stress such as the disease caused by COVID-19. The development and growth of existing units, as well as the creation of new ones where they do not exist, could be a basic tool for the medicine of the future.</p>","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/92/ff/revespquimioter-36-392.PMC10336309.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9832639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Medel-Plaza, A Auñón, A Blanco, J García-Cañete, L Salar-Vidal, J Esteban
{"title":"Periprosthetic joint infection caused by Haemophilus parainfluenzae. Case report and literature review.","authors":"M Medel-Plaza, A Auñón, A Blanco, J García-Cañete, L Salar-Vidal, J Esteban","doi":"10.37201/req/127.2022","DOIUrl":"https://doi.org/10.37201/req/127.2022","url":null,"abstract":"Rev Esp Quimioter 2023;36(3): 325-328 325 of progressive pain, and a possible loosening of the prosthesis was observed on radiographs. C-reactive protein (CRP) was 3 mg/dL and erythrocyte sedimentation rate (ESR) of 42 mm/h in addition to abundant joint effusion. An arthrocentesis for culture and study of the joint fluid was performed. Cell count was 6,280 cells/mm3 (85% polymorphonuclears), with glucose 177.0 mg/dl and CRP 6.84 mg/dl. This sample was inoculated in the following culture media: Tryptic soy sheep blood agar (TSS), chocolate agar (CHA), Shaedler-5% sheep blood agar (SCS), MacConkey agar (McC), and part of the fluid was also inoculated in a blood culture bottle (BactAlert), all from Biomérieux Marcy l’Etoile, France). TSS, CHA and McC were incubated at 37oC in a 5% CO2 atmosphere. SCS was incubated in an anaerobic atmosphere at 37oC. All media were incubated for 15 days.","PeriodicalId":21232,"journal":{"name":"Revista Espanola De Quimioterapia","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/b2/revespquimioter-36-325.PMC10238792.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9574462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}