[Macrolide-resistant Mycoplasma pneumoniae: Do we know the situation in Europe?]

IF 1.9 4区 医学 Q4 MICROBIOLOGY
A I Álvaro Varela, A Aguinaga Pérez, A Navascués Ortega, J Castilla Catalán, C Ezpeleta Baquedano
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引用次数: 0

Abstract

Mycoplasma pneumoniae is a bacterium that lacks a cell wall. It produces infections all It produces infections world-wide, in epidemic outbreaks every 4-7 years, or endemically. Its clinical manifestations occur mostly in the respiratory tract and it is a common cause of atypical pneumonia. The treatment is with macrolides, tetracyclines or fluoroquinolones. Since 2000, an increase in resistance to macrolides has been detected worldwide, being more frequent in Asia. In Europe the frequency of resistance ranges between 1% and 25%, depending on the country. Molecular techniques and serology techniques provides very high sensitivity in diagnostic confirmation, being very useful for detecting and controlling M. pneumoniae outbreaks. The detection of resistance to macrolides requires a sequencing technique.

耐大环内酯肺炎支原体:我们了解欧洲的情况吗?]
肺炎支原体是一种没有细胞壁的细菌。它在世界范围内产生感染,在每4-7年爆发一次的流行病中,或地方性地产生感染。其临床表现多见于呼吸道,是引起非典型肺炎的常见病因。治疗方法是大环内酯类、四环素类或氟喹诺酮类药物。自2000年以来,在世界范围内发现了对大环内酯类药物耐药性的增加,在亚洲更为常见。在欧洲,根据国家的不同,耐药性的频率在1%到25%之间。分子技术和血清学技术在诊断确认方面具有很高的灵敏度,对发现和控制肺炎支原体暴发非常有用。大环内酯类耐药的检测需要测序技术。
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来源期刊
CiteScore
2.90
自引率
10.50%
发文量
146
审稿时长
>12 weeks
期刊介绍: The official journal of the Sociedad Española de Quimioterapia (Spanish Society of Chemotherapy), publishes articles that further knowledge and advance the science and application of antimicrobial chemotherapy with antibiotics and antifungal, antiviral and antiprotozoal agents primarily in human medicine. Authors sign an exclusive license agreement, where authors have copyright but license exclusive rights in their article to the Publisher. All manuscripts are free open access. Revista Española de Quimioterapia includes the following sections: reviews, original articles, brierf reports, letters, and consensus documents.
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