耐大环内酯肺炎支原体:我们了解欧洲的情况吗?]

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
A I Álvaro Varela, A Aguinaga Pérez, A Navascués Ortega, J Castilla Catalán, C Ezpeleta Baquedano
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引用次数: 0

摘要

肺炎支原体是一种没有细胞壁的细菌。它在世界范围内产生感染,在每4-7年爆发一次的流行病中,或地方性地产生感染。其临床表现多见于呼吸道,是引起非典型肺炎的常见病因。治疗方法是大环内酯类、四环素类或氟喹诺酮类药物。自2000年以来,在世界范围内发现了对大环内酯类药物耐药性的增加,在亚洲更为常见。在欧洲,根据国家的不同,耐药性的频率在1%到25%之间。分子技术和血清学技术在诊断确认方面具有很高的灵敏度,对发现和控制肺炎支原体暴发非常有用。大环内酯类耐药的检测需要测序技术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Macrolide-resistant Mycoplasma pneumoniae: Do we know the situation in Europe?]

Mycoplasma pneumoniae is a bacterium that lacks a cell wall. It produces infections all It produces infections world-wide, in epidemic outbreaks every 4-7 years, or endemically. Its clinical manifestations occur mostly in the respiratory tract and it is a common cause of atypical pneumonia. The treatment is with macrolides, tetracyclines or fluoroquinolones. Since 2000, an increase in resistance to macrolides has been detected worldwide, being more frequent in Asia. In Europe the frequency of resistance ranges between 1% and 25%, depending on the country. Molecular techniques and serology techniques provides very high sensitivity in diagnostic confirmation, being very useful for detecting and controlling M. pneumoniae outbreaks. The detection of resistance to macrolides requires a sequencing technique.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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