Reviews in Medical Virology最新文献

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Dengue Infection During Pregnancy and Adverse Birth Outcomes: A Systematic Review and Meta-Analysis. 孕期登革热感染与不良出生结果:系统回顾与元分析》。
IF 9 2区 医学
Reviews in Medical Virology Pub Date : 2024-09-01 DOI: 10.1002/rmv.2582
Muhammed Shabil, Mahalaqua Nazli Khatib, Quazi Syed Zahiruddin, M M Rekha, Mandeep Kaur, Bindu Rani, Apurva Koul, M Ravi Kumar, Ashish Singh Chauhan, Nishant Rai, Sanjit Sah, Sorabh Lakhanpal, Ganesh Bushi
{"title":"Dengue Infection During Pregnancy and Adverse Birth Outcomes: A Systematic Review and Meta-Analysis.","authors":"Muhammed Shabil, Mahalaqua Nazli Khatib, Quazi Syed Zahiruddin, M M Rekha, Mandeep Kaur, Bindu Rani, Apurva Koul, M Ravi Kumar, Ashish Singh Chauhan, Nishant Rai, Sanjit Sah, Sorabh Lakhanpal, Ganesh Bushi","doi":"10.1002/rmv.2582","DOIUrl":"10.1002/rmv.2582","url":null,"abstract":"<p><p>Dengue is a rapidly spreading mosquito-borne viral disease, posing significant public health challenges in tropical and subtropical regions. This systematic review and meta-analysis aimed to evaluate the relationship between maternal dengue virus infection and adverse birth outcomes. A literature search was conducted in PubMed, Embase, and web of science databases until April 2024. Observational studies examining the association between laboratory-confirmed maternal dengue infection and adverse birth outcomes such as preterm birth, low birth weight (LBW), small for gestational age (SGA), stillbirth, and postpartum haemorrhage were included. Data were extracted, and risk of bias was assessed using the Newcastle-Ottawa Scale. Random-effects meta-analysis models were used to pool data in R software (V 4.3). Twenty studies met the inclusion criteria. The pooled prevalence of preterm birth among dengue-affected pregnancies was 18.3% (95% CI: 12.6%-25.8%), with an OR of 1.21 (95% CI: 0.78-1.89). For LBW, the pooled prevalence was 17.1% (95% CI: 10.4%-26.6%), with an OR of 1.00 (95% CI: 0.69-1.41). SGA had a pooled prevalence of 11.2% (95% CI: 2.7%-36.9%) and an OR of 0.93 (95% CI: 0.41-2.14). The prevalence of stillbirth was 3.3% (95% CI: 1.6%-6.8%), with significant associations found in some studies (RR: 2.67; 95% CI: 1.09-6.57). Postpartum haemorrhage had an OR of 1.97 (95% CI: 0.53-2.69). While maternal dengue infection was associated with a higher prevalence of preterm birth and LBW, the associations were not statistically significant. Significant associations were observed for stillbirth in specific studies. Further research with standardized methodologies is needed to clarify these relationships and identify potential mechanisms.</p>","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"34 5","pages":"e2582"},"PeriodicalIF":9.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of HIV Upon the PCI Results: A Systematic Review and Meta-Analysis. 艾滋病毒对 PCI 结果的影响:系统回顾与元分析。
IF 9 2区 医学
Reviews in Medical Virology Pub Date : 2024-09-01 DOI: 10.1002/rmv.2572
Amr Ehab El-Qushayri, Mohammad Rashidul Hashan, Md Mahfuj Alam, Muhammad Sanowar Khan, Nasser G Alqahtani
{"title":"The Impact of HIV Upon the PCI Results: A Systematic Review and Meta-Analysis.","authors":"Amr Ehab El-Qushayri, Mohammad Rashidul Hashan, Md Mahfuj Alam, Muhammad Sanowar Khan, Nasser G Alqahtani","doi":"10.1002/rmv.2572","DOIUrl":"10.1002/rmv.2572","url":null,"abstract":"<p><p>The aim of this systematic review and meta-analysis was to comprehensively evaluate the latest evidences and summarise the impact of HIV on PCI outcomes. A PRISMA guided literature search was conducted on 14 February 2024 in Web of Science, PubMed, Virtual Health Library, Google Scholar and Scopus. We searched with the term '(\"percutaneous coronary intervention\" OR \"PCI\") AND (\"human immunodeficiency virus\" OR \"HIV\" OR \"acquired immunodeficiency syndrome\" OR \"AIDS\")' after selecting the keywords from randomly chosen included papers. We included 8 papers of 781 screened records. HIV (+) patients had significant in-hospital, 1-year and overall (event at the last follow up point) all-cause mortality compared to HIV (-) group (OR: 1.73, 95%CI: 1.57-1.90, p < 0.01), (OR: 1.39, 95%CI: 1.07-1.81, p = 0.01) and (OR: 1.69, 95%CI: 1.55-1.85, p < 0.01), respectively. HIV (+) patients had significantly higher odds of developing MACE (OR: 1.35, 95%CI: 1.12-1.62, p = 0.001) compared to the HIV (-) group. No differences between both groups were detected regarding in-hospital and overall CV mortality, TVR, TLR, post-PCI TIMI grade 3 flow, cerebrovascular accidents and recurrent coronary events (p > 0.05). Our study revealed that people with HIV who underwent PCI in this modern era may have worse short and long-term PCI outcomes. This finding highlights the need for specialised cardiovascular care protocols for the HIV population. However, enhanced clinical management and preventative measures are imperative to improve PCI success rates in patients with HIV.</p>","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"34 5","pages":"e2572"},"PeriodicalIF":9.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Neurotropic Viruses in Brain Metastasis of Breast Cancer: Mechanisms and Therapeutic Implications. 神经性病毒在乳腺癌脑转移中的作用:机制与治疗意义》。
IF 9 2区 医学
Reviews in Medical Virology Pub Date : 2024-09-01 DOI: 10.1002/rmv.2584
Ziran Qiu, Xinyu Liu, Wenqing Cao, Rui Li, Jun Yang, Chengyu Wang, Zhong Li, Xiaoqin Yao, Yuan Chen, Chunhua Ye, Shanzheng Chen, Na Jin
{"title":"Role of Neurotropic Viruses in Brain Metastasis of Breast Cancer: Mechanisms and Therapeutic Implications.","authors":"Ziran Qiu, Xinyu Liu, Wenqing Cao, Rui Li, Jun Yang, Chengyu Wang, Zhong Li, Xiaoqin Yao, Yuan Chen, Chunhua Ye, Shanzheng Chen, Na Jin","doi":"10.1002/rmv.2584","DOIUrl":"10.1002/rmv.2584","url":null,"abstract":"<p><p>Neurotropic viruses have been implicated in altering the central nervous system microenvironment and promoting brain metastasis of breast cancer through complex interactions involving viral entry mechanisms, modulation of the blood-brain barrier, immune evasion, and alteration of the tumour microenvironment. This narrative review explores the molecular mechanisms by which neurotropic viruses such as Herpes Simplex Virus, Human Immunodeficiency Virus, Japanese Encephalitis Virus, and Rabies Virus facilitate brain metastasis, focusing on their ability to disrupt blood-brain barrier integrity, modulate immune responses, and create a permissive environment for metastatic cell survival and growth within the central nervous system. Current therapeutic implications and challenges in targeting neurotropic viruses to prevent or treat brain metastasis are discussed, highlighting the need for innovative strategies and multidisciplinary approaches in virology, oncology, and immunology.</p>","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"34 5","pages":"e2584"},"PeriodicalIF":9.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Gut Microbiota in Dengue. 肠道微生物群在登革热中的作用。
IF 9 2区 医学
Reviews in Medical Virology Pub Date : 2024-09-01 DOI: 10.1002/rmv.2577
Adriana Pedreañez, Yenddy Carrero, Renata Vargas, Juan P Hernandez-Fonseca, Hugo Hernandez-Fonseca, Jesús A Mosquera
{"title":"Role of Gut Microbiota in Dengue.","authors":"Adriana Pedreañez, Yenddy Carrero, Renata Vargas, Juan P Hernandez-Fonseca, Hugo Hernandez-Fonseca, Jesús A Mosquera","doi":"10.1002/rmv.2577","DOIUrl":"10.1002/rmv.2577","url":null,"abstract":"<p><p>Dengue is a disease caused by a flavivirus (DENV) and transmitted by the bite of a mosquito, primarily the Aedes aegypti and Aedes albopictus species. Previous studies have demonstrated a relationship between the host gut microbiota and the evolution of dengue. It seems to be a bidirectional relationship, in which the DENV can affect the microbiota by inducing alterations related to intestinal permeability, leading to the release of molecules from microbiota dysbiosis that can influence the evolution of dengue. The role of angiotensin II (Ang II) in the microbiota/dengue relationship is not well understood, but it is known that the renin-angiotensin system (RAS) is present in the intestinal tract and interacts with the gut microbiota. The possible effect of Ang II on the microbiota/Ang II/dengue relationship can be summarised as follows: the presence of Ang II induced hypertension, the increase in angiotensinogen, chymase, and microRNAs during the disease, the induction of vascular dysfunction, the production of trimethylamine N-oxide and the brain/microbiota relationship, all of which are elements present in dengue that could be part of the microbiota/Ang II/dengue interactions. These findings suggest the potential use of Ang II synthesis blockers and the use of AT1 receptor antagonists as therapeutic drugs in dengue.</p>","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"34 5","pages":"e2577"},"PeriodicalIF":9.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142111476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanoparticle-Based Therapies for Neurotropic Viral Infections: Mechanisms, Challenges, and Future Prospects. 基于纳米粒子的神经病毒感染疗法:机制、挑战和未来展望》。
IF 9 2区 医学
Reviews in Medical Virology Pub Date : 2024-09-01 DOI: 10.1002/rmv.2575
Min Yang, Chuanbo Ding, Ting Zhao, Ge Song, Tingting Liu, Zeqi Li, Ying Zhang
{"title":"Nanoparticle-Based Therapies for Neurotropic Viral Infections: Mechanisms, Challenges, and Future Prospects.","authors":"Min Yang, Chuanbo Ding, Ting Zhao, Ge Song, Tingting Liu, Zeqi Li, Ying Zhang","doi":"10.1002/rmv.2575","DOIUrl":"10.1002/rmv.2575","url":null,"abstract":"<p><p>Neurotropic viral infections pose a significant challenge due to their ability to target the central nervous system and cause severe neurological complications. Traditional antiviral therapies face limitations in effectively treating these infections, primarily due to the blood-brain barrier, which restricts the delivery of therapeutic agents to the central nervous system. Nanoparticle-based therapies have emerged as a promising approach to overcome these challenges. Nanoparticles offer unique properties that facilitate drug delivery across biological barriers, such as the blood-brain barrier, and can be engineered to possess antiviral activities.</p>","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"34 5","pages":"e2575"},"PeriodicalIF":9.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Virus-Induced Host Chemokine CCL2 in COVID-19 Pathogenesis: Potential Prognostic Marker and Target of Anti-Inflammatory Strategy. COVID-19发病机制中的病毒诱导宿主趋化因子CCL2:潜在的预后标志物和抗炎策略的目标。
IF 9 2区 医学
Reviews in Medical Virology Pub Date : 2024-09-01 DOI: 10.1002/rmv.2578
Abdul Wahid Ansari, Fareed Ahmad, Majid Ali Alam, Thesni Raheed, Ahmed Zaqout, Muna Al-Maslamani, Aamir Ahmad, Joerg Buddenkotte, Abdullatif Al-Khal, Martin Steinhoff
{"title":"Virus-Induced Host Chemokine CCL2 in COVID-19 Pathogenesis: Potential Prognostic Marker and Target of Anti-Inflammatory Strategy.","authors":"Abdul Wahid Ansari, Fareed Ahmad, Majid Ali Alam, Thesni Raheed, Ahmed Zaqout, Muna Al-Maslamani, Aamir Ahmad, Joerg Buddenkotte, Abdullatif Al-Khal, Martin Steinhoff","doi":"10.1002/rmv.2578","DOIUrl":"10.1002/rmv.2578","url":null,"abstract":"<p><p>A wide variety of inflammatory mediators, mainly cytokines and chemokines, are induced during SARS CoV-2 infection. Among these proinflammatory mediators, chemokines tend to play a pivotal role in virus-mediated immunopathology. The C-C chemokine ligand 2 (CCL2), also known as monocyte chemoattractant protein-1 (MCP-1) is a potent proinflammatory cytokine and strong chemoattractant of monocytes, macrophages and CD4+ T cells bearing C-C chemokine receptor type-2 (CCR2). Besides controlling immune cell trafficking, CCL2 is also involved in multiple pathophysiological processes including systemic hyperinflammation associated cytokine release syndrome (CRS), organ fibrosis and blood coagulation. These pathological features are commonly manifested in severe and fatal cases of COVID-19. Given the crucial role of CCL2 in COVID-19 pathogenesis, the CCL2:CCR2 axis may constitute a potential therapeutic target to control virus-induced hyperinflammation and multi-organ dysfunction. Herein we describe recent advances on elucidating the role of CCL2 in COVID-19 pathogenesis, prognosis, and a potential target of anti-inflammatory interventions.</p>","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"34 5","pages":"e2578"},"PeriodicalIF":9.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Authors' Response: Safety and Efficacy of COVID-19 Vaccines: A Systematic Review and Meta-Analysis of Controlled and Randomized Clinical Trials. 作者回复:COVID-19 疫苗的安全性和有效性:对照和随机临床试验的系统回顾和元分析》。
IF 9 2区 医学
Reviews in Medical Virology Pub Date : 2024-09-01 DOI: 10.1002/rmv.2573
Jayesh Beladiya, Anup Kumar, Yogesh Vasava, Krupanshu Parmar, Dipanshi Patel, Sandip Patel, Sandip Dholakia, Devang Sheth, Sai H S Boddu, Chirag A Patel
{"title":"Authors' Response: Safety and Efficacy of COVID-19 Vaccines: A Systematic Review and Meta-Analysis of Controlled and Randomized Clinical Trials.","authors":"Jayesh Beladiya, Anup Kumar, Yogesh Vasava, Krupanshu Parmar, Dipanshi Patel, Sandip Patel, Sandip Dholakia, Devang Sheth, Sai H S Boddu, Chirag A Patel","doi":"10.1002/rmv.2573","DOIUrl":"10.1002/rmv.2573","url":null,"abstract":"","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"34 5","pages":"e2573"},"PeriodicalIF":9.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141862055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blood-borne viruses and neurological manifestations: An overview. 血源性病毒与神经系统表现:概述。
IF 9 2区 医学
Reviews in Medical Virology Pub Date : 2024-07-01 DOI: 10.1002/rmv.2552
Yan Xu, Bo Yu
{"title":"Blood-borne viruses and neurological manifestations: An overview.","authors":"Yan Xu, Bo Yu","doi":"10.1002/rmv.2552","DOIUrl":"10.1002/rmv.2552","url":null,"abstract":"<p><p>Infections caused by blood-borne viruses, such as human immunodeficiency virus (HIV), human T-lymphotropic virus (HTLV), hepatitis C virus (HCV), and hepatitis B virus (HBV), are systemic diseases that can lead to a wide range of pathological manifestations. Besides causing severe immune and hepatic disorders, these viral pathogens can also induce neurological dysfunctions via both direct and indirect mechanisms. Neurological dysfunctions are one of the most common manifestations caused by these viruses that can also serve as indicators of their infection, impacting the clinical presentation of the disease. The main neurological manifestations of these blood-borne viral pathogens consist of several central and peripheral nervous system (CNS and PNS, respectively) dysfunctions. The most common neurological manifestations of HIV, HTLV, HCV, and HBV include HIV-associated peripheral neuropathy (PN), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and HCV-/HBV-associated PN, respectively. Nonetheless, patients infected with these viruses may experience other neurological disorders, either associated with these conditions or manifesting in isolation, which can often go unnoticed or undiagnosed by physicians. The present review aims to provide an overview of the latest evidence on the relationship between blood-borne viruses and neurological disorders to highlight neurological conditions that may be somewhat overlooked by mainstream literature and physicians.</p>","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"34 4","pages":"e2552"},"PeriodicalIF":9.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fluvoxamine and long COVID: Post-acute recovery. 氟伏沙明和长COVID:急性期后的恢复。
IF 9 2区 医学
Reviews in Medical Virology Pub Date : 2024-07-01 DOI: 10.1002/rmv.2557
Angela M Reiersen, Charles F Zorumski, Eric J Lenze
{"title":"Fluvoxamine and long COVID: Post-acute recovery.","authors":"Angela M Reiersen, Charles F Zorumski, Eric J Lenze","doi":"10.1002/rmv.2557","DOIUrl":"10.1002/rmv.2557","url":null,"abstract":"","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"34 4","pages":"e2557"},"PeriodicalIF":9.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatitis A in Latin America: The current scenario. 拉丁美洲的甲型肝炎:现状。
IF 9 2区 医学
Reviews in Medical Virology Pub Date : 2024-07-01 DOI: 10.1002/rmv.2566
Viviana E Ré, Ezequiel Ridruejo, Anabella C Fantilli, Bruna Damásio Moutinho, María Belén Pisano, Mário Guimarães Pessoa
{"title":"Hepatitis A in Latin America: The current scenario.","authors":"Viviana E Ré, Ezequiel Ridruejo, Anabella C Fantilli, Bruna Damásio Moutinho, María Belén Pisano, Mário Guimarães Pessoa","doi":"10.1002/rmv.2566","DOIUrl":"10.1002/rmv.2566","url":null,"abstract":"<p><p>This review aims to gather and disseminate updated information regarding hepatitis A virus (HAV) in Latin America (LA) in the last 11 years, including seroprevalence, post-vaccination studies, virus detection in aqueous matrices and food samples, and outbreak reports. Only 24 seroprevalence studies were published between 2012 and 2023 with 55%-100% reported prevalences of anti-HAV IgG. Among the 25 LA countries, only eight of them have introduced HAV vaccines into their immunisation programs. Outbreaks of hepatitis A occurred between 2017-2019, mainly affecting men who have sex with men in Argentina, Brazil and Chile, probably as a consequence of the abrupt decline of young adults' immunity. This could be due to that young adult have never been infected in childhood (due to socio-health improvements) and are above the cut-off ages to be included when the vaccination programs were introduced. Although scarce, studies focused on environmental and food HAV surveillance have shown viral presence in these samples. Surface waters presented HAV detections between 1.2% and 86.7%, and untreated wastewaters between 2.8% and 70.9%. Genotypes found in all cases were IA and IC. The only wastewater-based epidemiology study showed to be a useful tool as a complement of traditional epidemiological surveillance. Only four LA countries have looked for HAV in food samples, with genome detection rates between 9% and 33%. Latin American HAV circulation scenario is changing. In countries where socioeconomic and sanitary conditions have not improved, the virus persists with high endemicity and the access to the vaccine should be re-evaluated by local governments. In countries where access to clean water, better sanitary conditions and HAV immunisation programs have been implemented, the number of cases among young adults seems to be increasing, alerting health authorities.</p>","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"34 4","pages":"e2566"},"PeriodicalIF":9.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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