Emerging Nipah Virus With Pandemic Potential and High Mortality Rates: Is the Scientific Community Learning From Former Pandemics?

IF 9 2区 医学 Q1 VIROLOGY
Doris Klingelhöfer, Markus Braun, Christina A Naser, Dörthe Brüggmann, David A Groneberg
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Abstract

As Nipah virus (NiV) infection is characterised by a possible pandemic risk, being currently limited to a small but deadly belt, the attention of other countries is essential. It has often been pointed out that NiV is an under-researched virus with a high-risk potential. This study aimed to show the global research history and status quo based on analyses of various chronological and geographical parameters, including socioeconomic characteristics and research funding. For this purpose, advanced analysis methods and visualisation techniques were applied, such as density equalisation mapping and cluster analysis. The correlation between the number of articles on NiV and the economic strength or intensity of financing per country is significant. However, the comparatively low scientific commitment of countries that are usually among the major players in global scientific publications and the declining scientific interest in NiV research combined with the prevailing knowledge gaps in NiV infectiology in conjunction with the risk of NiV spreading to other areas is extremely threatening. Research on previous viruses such as Corona and mpox shows an equally short-term interest, which has led to an insufficiently prepared situation in the run-up to outbreaks, making it hard to find quick and effective solutions. As often said, the NiV infection belt is small but deadly, but global travel and trade increase the risk of spreading. The scientific community worldwide must be prepared for the possible spread of infections that pose a pandemic risk.

具有大流行潜力和高死亡率的新出现的尼帕病毒:科学界是否从以前的大流行中吸取教训?
由于尼帕病毒感染的特点是可能存在大流行风险,目前仅限于小范围但致命的地区,因此其他国家的关注至关重要。人们经常指出,新冠病毒是一种研究不足的病毒,具有潜在的高风险。本研究旨在通过对各种时间和地理参数的分析,包括社会经济特征和研究经费,来展示全球研究的历史和现状。为此,应用了先进的分析方法和可视化技术,如密度均衡映射和聚类分析。关于NiV的文章数量与每个国家的经济实力或融资强度之间的相关性是显著的。然而,那些通常是全球科学出版物主要参与者的国家相对较低的科学承诺,以及对新冠病毒研究的科学兴趣下降,再加上新冠病毒感染学方面普遍存在的知识差距,再加上新冠病毒传播到其他地区的风险,这些都是极具威胁性的。对以前的病毒,如冠状病毒和痘病毒的研究显示出同样的短期兴趣,这导致在疫情爆发前准备不足,难以找到快速有效的解决办法。正如人们常说的,新冠病毒感染带虽小但致命,但全球旅行和贸易增加了传播的风险。全世界的科学界必须为可能造成大流行的感染传播做好准备。
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来源期刊
Reviews in Medical Virology
Reviews in Medical Virology 医学-病毒学
CiteScore
21.40
自引率
0.90%
发文量
88
期刊介绍: Reviews in Medical Virology aims to provide articles reviewing conceptual or technological advances in diverse areas of virology. The journal covers topics such as molecular biology, cell biology, replication, pathogenesis, immunology, immunization, epidemiology, diagnosis, treatment of viruses of medical importance, and COVID-19 research. The journal has an Impact Factor of 6.989 for the year 2020. The readership of the journal includes clinicians, virologists, medical microbiologists, molecular biologists, infectious disease specialists, and immunologists. Reviews in Medical Virology is indexed and abstracted in databases such as CABI, Abstracts in Anthropology, ProQuest, Embase, MEDLINE/PubMed, ProQuest Central K-494, SCOPUS, and Web of Science et,al.
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