Reviews in Medical Virology最新文献

Crosstalk Between Viral Envelop-E Protein and Host Innate Immune System: Exploring Pharmacological Targets and Agents. 病毒包膜e蛋白与宿主先天免疫系统之间的串扰：探索药理学靶点和药物。

IF 6.6 2区医学

Reviews in Medical Virology Pub Date : 2025-09-01 DOI: 10.1002/rmv.70067

Satyam Shekhar, Arvind Maurya, Sandeep, Subrat Kumar Bhattamisra, Gireesh Kumar Singh, Debapriya Garabadu

{"title":"Crosstalk Between Viral Envelop-E Protein and Host Innate Immune System: Exploring Pharmacological Targets and Agents.","authors":"Satyam Shekhar, Arvind Maurya, Sandeep, Subrat Kumar Bhattamisra, Gireesh Kumar Singh, Debapriya Garabadu","doi":"10.1002/rmv.70067","DOIUrl":"10.1002/rmv.70067","url":null,"abstract":"The Envelope (E)-protein is a key structural element of enveloped viruses that plays a significant role in host-pathogen interactions, viral growth, and hijacking of host innate immune system. Due to lack of antiviral agents and significant adverse effects and less affordability of vaccines, the E-protein targeted drug development is gaining critical attention among the researchers. The present review explores the structural and genomic diversities of E-protein among animal viruses with special interest to flaviviruses, coronaviruses, and herpesviruses. E-protein's viroporin activity damages host cell membrane and induces inflammation that advances the disease progression. The review also explains the viroporin-mediated NOD-like receptor family pyrin domain-containing 3 (NLRP3), Toll-like receptors (TLRs), nucleotide-binding oligomerisation domain (NOD)-like receptors (NLRs), and retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs)-linked cellular mechanisms in virus-mediated inflammation. The E-protein is considered an alternative promising antiviral target as its functional domain is conserved. This review further enlists the natural, and synthetic inhibitors of E-protein in the development of antiviral agents based on computational, in vitro, and in vivo studies. The E-protein's universal conservation ability to fasten to cellular membranes and limited structural data imparts significant challenge to selective drug inhibition. The present review highlights that the E-protein together with multiple viral factors will boost treatment performance while minimising viral resistance. In addition, broad-range inhibitors targeting E-proteins have the potential to produce single treatment solutions in combating viral infections including several viral strains. In conclusion, E-protein targeted drug would be beneficial in developing potential antiviral agents with high drug specificity, and less viral resistance.","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"35 5","pages":"e70067"},"PeriodicalIF":6.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144848586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Dual Role of Autophagy in the Pathogenesis of Arboviruses With a Focus on JEV and DENV. 自噬在虫媒病毒发病机制中的双重作用——以乙脑病毒和登革热病毒为重点。

IF 6.6 2区医学

Reviews in Medical Virology Pub Date : 2025-09-01 DOI: 10.1002/rmv.70073

HaoNing Wang, YuHan Wang, YuFei Li, Xi Chen, XiaoDi Wang, XiaoLong Wang, ShaoPeng Yu

{"title":"The Dual Role of Autophagy in the Pathogenesis of Arboviruses With a Focus on JEV and DENV.","authors":"HaoNing Wang, YuHan Wang, YuFei Li, Xi Chen, XiaoDi Wang, XiaoLong Wang, ShaoPeng Yu","doi":"10.1002/rmv.70073","DOIUrl":"https://doi.org/10.1002/rmv.70073","url":null,"abstract":"Japanese encephalitis virus (JEV) and dengue virus (DENV) are two major arboviruses known as significant public health issues worldwide. Arboviruses are a heterogeneous group of vector-borne viruses that are clinically associated with various consequences ranging from asymptomatic infections to serious forms of haemorrhagic fever marked by bleeding complications. Despite advancements in understanding the pathogenesis of arboviruses the molecular mechanisms underlying clinical outcomes remain incompletely understood. Autophagy, a cellular process crucial for maintaining homeostasis through the degradation and recycling of cellular components, has emerged as a key player in viral infections. Recent studies have highlighted the dual role of autophagy in modulating the host-pathogen interaction, where it may serve as both a defence mechanism against viral replication and a tool exploited by viruses to enhance survival. In the case of arboviruses, autophagy appears to influence viral replication and modulate the host immune response, contributing to both viral persistence and the extent of clinical outcomes. This review describes the role of autophagy in the pathogenesis of JEV and DENV, focusing on the molecular mechanisms that govern autophagic processes and their interaction with JEV and DENV replication. It shows that how JEV and DENV manipulates host autophagic machinery to its advantage, the impact of autophagic dysregulation on disease severity, and potential therapeutic strategies targeting autophagy to mitigate viral encephalitis. Understanding the intricate balance between autophagy and JEV and DENV may provide novel insights into therapeutic approaches for combating these viruses.","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"35 5","pages":"e70073"},"PeriodicalIF":6.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145125953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Neurophysiology in Investigating Neuropathology of Vertical Zika Virus Infection. 神经生理学在研究垂直寨卡病毒感染的神经病理学中的作用。

IF 6.6 2区医学

Reviews in Medical Virology Pub Date : 2025-09-01 DOI: 10.1002/rmv.70068

Dimitri Marques Abramov, Daniel de Souza E Silva, Adriana Salvio Rios, Cecilia Hedin-Pereira, Alessandra Augusta Barroso Penna E Costa, Maria Elizabeth Lopes Moreira

引用次数: 0

Prevalence and the Mutual Relationship Between Chronic Obstructive Pulmonary Disease and Arbovirus: A Comprehensive Systematic Review and Meta-Analysis of Current Evidence. 慢性阻塞性肺疾病与虫媒病毒的患病率及其相互关系：一项对现有证据的综合系统评价和荟萃分析

IF 6.6 2区医学

Reviews in Medical Virology Pub Date : 2025-09-01 DOI: 10.1002/rmv.70061

Xiaodan Li, Shanshan Wang, Xiaoyu Ma, Ying Tang

{"title":"Prevalence and the Mutual Relationship Between Chronic Obstructive Pulmonary Disease and Arbovirus: A Comprehensive Systematic Review and Meta-Analysis of Current Evidence.","authors":"Xiaodan Li, Shanshan Wang, Xiaoyu Ma, Ying Tang","doi":"10.1002/rmv.70061","DOIUrl":"10.1002/rmv.70061","url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) is a progressive condition affecting the lungs, marked by persistent respiratory symptoms. The prevalence and the risk of COPD in arboviruses types is not fully addressed clinically. We aim to determine the prevalence and the risk of COPD in arboviruses by a systematic review and meta-analysis. A comprehensive literature review was conducted systematically across several databases, including PubMed/Medline, Scopus, Web of Science (WoS), and Embase to find relevant studies up to April 30, 2025. A random-effects model was employed to analyse the relationship between the presence of arboviruses and the clinical implications associated with COPD. This systematic review and meta-analysis was conducted following the standard methodology outlined in the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) protocol. We identified 17 studies that met the inclusion criteria for this analysis. The prevalence of COPD in individuals with arbovirus was (10%, 95% CI 6%-13.5%). Moreover, the prevalence of COPD was in dengue virus (5.2%, 95% CI 3.2%-8.2%), chikungunya virus (26.4%, 95% CI 9.7%-54.3%) and West Nile virus (7.6%, 95% CI 4.9%-11.7%). The summary odds ratio (SOR) showed a significant risk of COPD in chikungunya virus (5.1, 95% CI 2.08-12.8) and West Nile virus (1.7, 95% CI 1.25-2.5) but not in patients with dengue virus. Subgroup analysis demonstrated significant association between severity COPD with age and type of study design. Higher prevalence of COPD was found in individuals with chikungunya virus compared with other arboviruses. Findings of the current study will help to public health practitioners and clinicians for better understanding and proper management of COPD in individuals with arbovirus in general population.","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"35 5","pages":"e70061"},"PeriodicalIF":6.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Database-Driven Surveillance of Lenacapavir Resistance Profiles in China: Analysis of HIV-1 Gag Sequences From People Living With HIV. 数据库驱动的中国Lenacapavir耐药监测：HIV-1 Gag序列分析

IF 6.6 2区医学

Reviews in Medical Virology Pub Date : 2025-09-01 DOI: 10.1002/rmv.70072

Defu Yuan, Yangyang Liu, Yueqi Yin, Shanshan Liu, Bei Wang

引用次数: 0

The Cerebral Haemorrhage and SARS-CoV-2: An Emerging Virus From a Meta-Analysis Perspective. 脑出血和SARS-CoV-2：从荟萃分析的角度看一种新兴病毒。

IF 6.6 2区医学

Reviews in Medical Virology Pub Date : 2025-09-01 DOI: 10.1002/rmv.70069

Yuxia Wang, Chao Zhang, Yunzhu Zhang, Zhuwei Zhang

{"title":"The Cerebral Haemorrhage and SARS-CoV-2: An Emerging Virus From a Meta-Analysis Perspective.","authors":"Yuxia Wang, Chao Zhang, Yunzhu Zhang, Zhuwei Zhang","doi":"10.1002/rmv.70069","DOIUrl":"10.1002/rmv.70069","url":null,"abstract":"The central nervous system is a potential target of the COVID-19 virus, and one of the devastating neurological consequences of this infection is cerebral haemorrhage (ICH). Cerebral haemorrhage is a leading cause of death worldwide. This study aimed to systematically review and analyse the existing literature on this topic and provide insights into the potential neurological consequences of COVID-19. A comprehensive search was conducted across the PubMed, Scopus, Web of Science, and Embase databases to extract relevant published data up to February 2025. This meta-analysis included 11 studies involving a total of 197,060 individuals. Subgroup analyses were performed based on the year of publication, hospital sampling wards, and study design. A critical appraisal was carried out using the Newcastle-Ottawa Scale (NOS) score. Risk was utilised as a measure of pooled effect size based on a random-effects model. In this analysis, we identified 11 articles that directly assessed the risk of cerebral haemorrhage. The reported risk of cerebral haemorrhage was five cases per 10,000 COVID-19 patients [0.005 (95% CI: 0.002-0.009), p < 0.001]. Notably, studies published in 2022 and 2023 indicated a significantly higher risk of cerebral haemorrhage compared to earlier years. COVID-19 patients admitted to the intensive care unit (ICU) faced an increased risk of cerebral haemorrhage compared to those admitted to general wards. Meta-regression analysis revealed a statistically significant association between the risk of cerebral haemorrhage and the type of wards in a hospital [0.0089 (95% CI: 0.0067-0.0112), p < 0.001], as well as the year of publication [0.0004 (95% CI: 0.0003-0.0008), p = 0.048]. Therefore, it is essential to evaluate COVID-19 patients admitted to the ICU in recent years for the potential occurrence of cerebral haemorrhage.","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"35 5","pages":"e70069"},"PeriodicalIF":6.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-COVID-19 Vaccination (or Long Vax) Syndrome: Putative Manifestation, Pathophysiology, and Therapeutic Options. covid -19后疫苗接种（或长疫苗）综合征：推定表现、病理生理学和治疗选择。

IF 6.6 2区医学

Reviews in Medical Virology Pub Date : 2025-09-01 DOI: 10.1002/rmv.70070

Shin Jie Yong, Tiff-Annie Kenny, Alice Halim, Bala Munipalli, Yousef N Alhashem, Hajir AlSaihati, Maha F Al-Subaie, Nawal A Al Kaabi, Mona A Al Fares, Mohammed Garout, Amal A Sabour, Maha A Alshiekheid, Zainab H Almansour, Jawaher Alotaibi, Hayam A Alrasheed, Aref A Alamri, Hawra Albayat, Ameera Saeed Alamodi, Huseyin Tombuloglu, Ranjan K Mohapatra, Ali Hazazi, Ali A Rabaan

{"title":"Post-COVID-19 Vaccination (or Long Vax) Syndrome: Putative Manifestation, Pathophysiology, and Therapeutic Options.","authors":"Shin Jie Yong, Tiff-Annie Kenny, Alice Halim, Bala Munipalli, Yousef N Alhashem, Hajir AlSaihati, Maha F Al-Subaie, Nawal A Al Kaabi, Mona A Al Fares, Mohammed Garout, Amal A Sabour, Maha A Alshiekheid, Zainab H Almansour, Jawaher Alotaibi, Hayam A Alrasheed, Aref A Alamri, Hawra Albayat, Ameera Saeed Alamodi, Huseyin Tombuloglu, Ranjan K Mohapatra, Ali Hazazi, Ali A Rabaan","doi":"10.1002/rmv.70070","DOIUrl":"10.1002/rmv.70070","url":null,"abstract":"With the global rollout of COVID-19 vaccines, vaccine safety remains a priority. Emerging concerns have raised the potential risk of a long COVID-like syndrome following vaccination, informally called long Vax and provisionally termed post-COVID-19 vaccination syndrome (PCVS). Our narrative review describes the putative manifestation, pathophysiology, and therapeutic approaches of PCVS based on the available evidence, mostly from case reports/series and observational studies. Our review noted that PCVS typically manifests within days to weeks post-vaccination, with symptoms lasting months to years. PCVS may present as recognized diagnoses such as postural orthostatic tachycardia syndrome (POTS), small-fibre neuropathy (SFN), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), or as long-term sequelae of myocarditis, vaccine-induced thrombotic thrombocytopaenia (VITT), or immune thrombocytopaenia purpura (ITP). Symptomatically, PCVS overlaps with long COVID, such as fatigue and brain fog, but PCVS may involve more frequent paraesthesia and less dyspnoea. We also review pathophysiological hypotheses of PCVS, focussing on the vaccine-derived spike protein and related immune responses. Finally, we discuss potential therapies used to treat patients with PCVS or related conditions, primarily documented in case reports/series, which could guide future clinical research. Overall, PCVS remains a poorly understood condition that requires more research to elucidate its prevalence, prognosis, risk factors, and treatments.","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"35 5","pages":"e70070"},"PeriodicalIF":6.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Overview of Ophthalmic Complications Associated With Emerging/Re-Emerging Viruses: Focus on ZIKV, DENV, SARS-CoV-2, and MPXV. 新发/再发病毒相关眼科并发症综述：重点关注ZIKV、DENV、SARS-CoV-2和MPXV。

IF 9 2区医学

Reviews in Medical Virology Pub Date : 2025-07-01 DOI: 10.1002/rmv.70056

Qian Li, Wenbo Jiao, Xiaolin Li, Lingling Liang

{"title":"An Overview of Ophthalmic Complications Associated With Emerging/Re-Emerging Viruses: Focus on ZIKV, DENV, SARS-CoV-2, and MPXV.","authors":"Qian Li, Wenbo Jiao, Xiaolin Li, Lingling Liang","doi":"10.1002/rmv.70056","DOIUrl":"https://doi.org/10.1002/rmv.70056","url":null,"abstract":"Infections caused by emerging and re-emerging viral pathogens are currently known as a significant global public health issue, affecting various human organ systems such as the ocular system. Several emerging and re-emerging viral infections, such as those caused by Zika virus (ZIKV), dengue virus (DENV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and monkeypox virus (MPXV), have been involved in the development of various ophthalmic disorders including uveitis, conjunctivitis, retinitis, optic neuritis, and more severe vision-threatening complications. The present review comprehensively describes the ophthalmic manifestations linked to these viruses, with a primary focus on their underlying pathogenesis, diverse clinical presentations, and the intricate potential mechanisms of viral invasion into ocular tissues. Describing the ocular involvement of emerging and re-emerging viral pathogens, particularly how they target and affect the ocular system, is critical for early diagnosis, appropriate management, and reducing long-term visual manifestations in affected patients. This review aims to address existing gaps in clinical knowledge and support timely ophthalmological management during emerging viral outbreaks.","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"35 4","pages":"e70056"},"PeriodicalIF":9.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cell Biology of Human Cytomegalovirus Latency: Implications for Pathogenesis and Treatment. 人巨细胞病毒潜伏期的细胞生物学：对发病机制和治疗的意义。

IF 6.6 2区医学

Reviews in Medical Virology Pub Date : 2025-07-01 DOI: 10.1002/rmv.70063

Matthew B Reeves

{"title":"Cell Biology of Human Cytomegalovirus Latency: Implications for Pathogenesis and Treatment.","authors":"Matthew B Reeves","doi":"10.1002/rmv.70063","DOIUrl":"10.1002/rmv.70063","url":null,"abstract":"Human cytomegalovirus (HCMV), like all herpes viruses, can establish lifelong infections of the host. This is due to the capacity to establish latency-a defining characteristic of herpes virus infection. In healthy individuals, pathology associated with HCMV infection is rare due, in part, to a robust immune response that controls replication. Consequently, in patients with impaired immune responses substantial pathogenesis is observed due to a failure of immunological control. In this review, I discuss the biology of latency and reactivation with an emphasis on aspects important for our understanding of pathogenesis and treatment. In particular, I will represent how fundamental understanding of the cellular and molecular details of viral latency have, and will continue to be, pivotal for attempts to therapeutically target latent HCMV with a view to reducing the burden of disease. This will include pharmacological and immunological therapies that utilise the modulation of both host and viral functions important for latency and reactivation as well as strategies to harness the very well characterised and prodigious immune response directed against replicating HCMV to target latent infections as well.","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"35 4","pages":"e70063"},"PeriodicalIF":6.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral Manifestations in the Post COVID-19 Condition: A Systematic Review With Meta-Analysis. COVID-19后口腔表现：一项系统综述和荟萃分析

IF 9 2区医学

Reviews in Medical Virology Pub Date : 2025-07-01 DOI: 10.1002/rmv.70057

Letícia Simeoni Avais, Elis Carolina Pacheco, Luisa Pereira de Oliveira Zanetti Gomes, Márcia Helena Baldani, Camila Marinelli Martins, Eliseu Alves Waldman, Jean Paul J Gonzalez, Tomoko Y Steen, Pollyanna Kássia de Oliveira Borges

{"title":"Oral Manifestations in the Post COVID-19 Condition: A Systematic Review With Meta-Analysis.","authors":"Letícia Simeoni Avais, Elis Carolina Pacheco, Luisa Pereira de Oliveira Zanetti Gomes, Márcia Helena Baldani, Camila Marinelli Martins, Eliseu Alves Waldman, Jean Paul J Gonzalez, Tomoko Y Steen, Pollyanna Kássia de Oliveira Borges","doi":"10.1002/rmv.70057","DOIUrl":"10.1002/rmv.70057","url":null,"abstract":"Post-COVID-19 condition, or Long COVID, is characterised by symptoms persisting or emerging beyond 12 weeks after acute infection. Among over 200 reported symptoms, oral manifestations such as taste loss and dry mouth have been identified. This systematic review reports the frequency and characteristics of these symptoms. Registered in PROSPERO and following PRISMA guidelines, the review included observational studies on COVID-19-positive adults presenting oral symptoms in the post-COVID-19 condition. A search in six databases (Medline/PubMed, Embase, Web of Science, Cochrane, SCOPUS, and LILACS) was conducted in January 2024. Risk of bias was assessed using Joanna Briggs Institute's critical appraisal tools, and certainty of evidence via GRADE. A meta-analysis using the inverse variance method estimated oral symptom prevalence. Of 4552 articles, 107 were included. Taste dysfunction persisted in 8% (95% CI 6%-10%) of patients beyond 12 weeks. Combined taste and smell alterations had a prevalence of 17% (95% CI 13%-21%). Less frequent symptoms included hyposalivation, periodontitis, mouth ulcers, tongue mucosal changes, facial tingling, sensitivity in the trigeminal nerve, difficulty swallowing, and lesions in the hard palate. Taste alterations were the most commonly reported symptom, underscoring the need for clinical recognition and appropriate management by oral health professionals. Additionally, the wide range of other oral manifestations highlights the necessity for further research to better understand their prevalence, underlying mechanisms, and clinical implications in post-COVID-19 patients.","PeriodicalId":21180,"journal":{"name":"Reviews in Medical Virology","volume":"35 4","pages":"e70057"},"PeriodicalIF":9.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12262108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0