RespirologyPub Date : 2025-06-27DOI: 10.1111/resp.70068
Udit Chaddha, Abhinav Agrawal, Septimiu Murgu, Uzair Ghori, Pere Trias-Sabria, Rosamaria Ortiz-Comino, Herve Dutau, Lutz Freitag, Stefano Gasparini, Pyng Lee, Christophe Dooms, Rocco Trisolini, Maria Lucia L Madariaga, Shuben Li, Lina Zuccatosta, Felix Herth, Hideo Saka, David Fielding, Masahide Oki, Antoni Rosell
{"title":"World Association for Bronchology and Interventional Pulmonology (WABIP) Guidelines on Airway Stenting for Benign Central Airway Obstruction.","authors":"Udit Chaddha, Abhinav Agrawal, Septimiu Murgu, Uzair Ghori, Pere Trias-Sabria, Rosamaria Ortiz-Comino, Herve Dutau, Lutz Freitag, Stefano Gasparini, Pyng Lee, Christophe Dooms, Rocco Trisolini, Maria Lucia L Madariaga, Shuben Li, Lina Zuccatosta, Felix Herth, Hideo Saka, David Fielding, Masahide Oki, Antoni Rosell","doi":"10.1111/resp.70068","DOIUrl":"https://doi.org/10.1111/resp.70068","url":null,"abstract":"<p><p>Benign central airway obstruction (BCAO) related strictures include post-intubation tracheal stenosis, post-tracheostomy tracheal stenosis, post-surgical or anastomotic stenosis, stenosis related to inflammatory disorders or infectious disorders, chemical injury or post radiotherapy. Techniques and thresholds for airway stenting for each of these unique conditions vary significantly across centres due to lack of guidance. The management of the airway stents once placed due to scarcity of data also has a similar knowledge void. This document aims to address these knowledge gaps by addressing relevant questions related to airway stenting in BCAO. A multidisciplinary, international group of 20 experts from 19 institutions across 12 countries with extensive experience in airway stenting in BCAO was convened as part of this guideline document through the World Association of Bronchology and Interventional Pulmonology (WABIP). A literature search was performed for reports addressing eight clinically relevant PICO questions. Recommendations addressing these questions were formulated using a systematic process involving the evaluation of published evidence, supplemented with expert experience when necessary. The panel participated in the development of the final recommendations using a modified Delphi technique.</p>","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144507983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirologyPub Date : 2025-06-27DOI: 10.1111/resp.70085
Nathan J Mortimer, Lauren K Troy
{"title":"Non-Intubated VATS for Interstitial Lung Disease Diagnosis: A Safer Technique or Too Soon to Tell?","authors":"Nathan J Mortimer, Lauren K Troy","doi":"10.1111/resp.70085","DOIUrl":"https://doi.org/10.1111/resp.70085","url":null,"abstract":"","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144507981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirologyPub Date : 2025-06-27DOI: 10.1111/resp.70086
T David Koster, Dirk-Jan Slebos
{"title":"Pneumothorax in Endobronchial Valve Therapy-Still a Lot to Be Learned.","authors":"T David Koster, Dirk-Jan Slebos","doi":"10.1111/resp.70086","DOIUrl":"https://doi.org/10.1111/resp.70086","url":null,"abstract":"","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144507982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirologyPub Date : 2025-06-16DOI: 10.1111/resp.70080
Shivanthan Shanthikumar
{"title":"Paediatric Asthma Readmissions in Australia: Is Our Care Good Enough?","authors":"Shivanthan Shanthikumar","doi":"10.1111/resp.70080","DOIUrl":"https://doi.org/10.1111/resp.70080","url":null,"abstract":"","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirologyPub Date : 2025-06-10DOI: 10.1111/resp.70072
Steven Luu, Olivia McGuiness, Collette Menadue, Amanda J Piper, Keith Wong, Brendon J Yee, Emma L Gray
{"title":"Inter-Night Variability of Nocturnal Pulse Oximetry in People Living With Motor Neuron Disease: A Retrospective Observational Study.","authors":"Steven Luu, Olivia McGuiness, Collette Menadue, Amanda J Piper, Keith Wong, Brendon J Yee, Emma L Gray","doi":"10.1111/resp.70072","DOIUrl":"https://doi.org/10.1111/resp.70072","url":null,"abstract":"<p><strong>Background and objective: </strong>Nocturnal pulse oximetry (NPO) is a simple and inexpensive assessment tool that has previously been shown to correlate with prognosis and timing of non-invasive ventilation (NIV) initiation in people living with motor neuron disease (plwMND). However, the optimal number of nights for measuring NPO has not been defined for this population, with other respiratory conditions exhibiting both low and high night-to-night variability in NPO parameters. This study aims to determine the inter-night variability in NPO data over three nights in plwMND.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of 132 studies in which plwMND underwent three consecutive nights of NPO. Intraclass correlation coefficients (ICC) were used to assess the reliability of key NPO parameters, including mean percentage of total recording time with oxygen saturation (SpO<sub>2</sub>) < 90% (T90), oxygen desaturation index (ODI), basal SpO<sub>2</sub> and nadir SpO<sub>2</sub>. The proportion of plwMND meeting NIV criteria based on single-night versus multi-night assessments was also compared.</p><p><strong>Results: </strong>Excellent reliability was observed for T90 (ICC(1) = 0.940) and ODI (ICC(1) = 0.901), while basal SpO<sub>2</sub> (ICC(1) = 0.845) and nadir SpO<sub>2</sub> (ICC(1) = 0.768) demonstrated good reliability. However, relying on a single-night NPO assessment failed to identify 12% of plwMND who met NIV criteria when evaluated over three nights.</p><p><strong>Conclusion: </strong>Despite good to excellent inter-night variability of NPO data in plwMND, multi-night NPO monitoring improves the accuracy of identifying plwMND requiring NIV. These findings support the need for multi-night assessments to enhance clinical decision-making in MND management.</p>","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirologyPub Date : 2025-06-10DOI: 10.1111/resp.70073
Jemma Haines, Jaclyn A Smith, Stephen J Fowler, Janelle Yorke
{"title":"Upper Airway Control Therapy (U-ACT): The Development of a Non-Pharmacological Intervention for Inducible Laryngeal Obstruction.","authors":"Jemma Haines, Jaclyn A Smith, Stephen J Fowler, Janelle Yorke","doi":"10.1111/resp.70073","DOIUrl":"https://doi.org/10.1111/resp.70073","url":null,"abstract":"<p><strong>Background and objective: </strong>Non-pharmacological intervention is the recommended gold standard for inducible laryngeal obstruction (ILO) treatment. Despite this, there is no standardised approach and interventions are poorly described. The objective was to develop and describe a standardised non-pharmacological intervention for ILO, for future testing of effectiveness.</p><p><strong>Methods: </strong>MRC guidelines for complex intervention development were followed; the methodological approach was structured using the INDEX principles. The multi-phase research stages were: (1) evidence review; (2) qualitative data collection from speech and language therapists (n = 7) and patients (n = 22); (3) intervention design and theoretical underpinning; (4) prototype survey feedback from Stage 2 participants; and (5) final intervention description, using a validated reporting framework.</p><p><strong>Results: </strong>Systematic review and synthesis of 14 studies (n = 527) identified key uncertainties and steered Stage 2 interviews. Framework analysis of qualitative data collected identified five overarching key themes for inclusion. The resulting 'Upper Airway Control Therapy' (U-ACT) intervention comprises two core components (education & empowerment; reliever breath control), four supporting components (bio-feedback training; prevention methods; supporting co-existing conditions; managing others' reactions to ILO) and a cross-cutting home practice component. U-ACT's mechanisms of action to bring about change includes 36 behaviour change techniques. Feedback on U-ACT protype was extremely positive; survey responders (n = 23; 87% response rate) strongly agreed to acceptability statements for all parameters surveyed [5-point Likert scale; median (range), 4.5, 3-5].</p><p><strong>Conclusion: </strong>The U-ACT intervention, developed with keystakeholders and underpinned with a programme theory, is fully manualised and ready for evaluation. If future testing proves clinical and cost effectiveness, it could be incorporated into existing ILO services.</p>","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirologyPub Date : 2025-06-10DOI: 10.1111/resp.70074
Mark Lavercombe
{"title":"Recommendations From the Medical Education Editor.","authors":"Mark Lavercombe","doi":"10.1111/resp.70074","DOIUrl":"https://doi.org/10.1111/resp.70074","url":null,"abstract":"","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring Benefits of Non-Intubated Surgery for Lung Biopsy in Interstitial Lung Disease.","authors":"Aude Nguyen, Timothée Jouitteau, Arnaud Bourdin, Anne-Sophie Gamez, Laurence Solovei, José Molina, Kheira Hireche","doi":"10.1111/resp.70067","DOIUrl":"https://doi.org/10.1111/resp.70067","url":null,"abstract":"<p><strong>Background and objectives: </strong>General anaesthesia with intubation is the standard technique for video-assisted thoracic surgery (VATS). However, non-intubated VATS (NIVATS) is emerging as a less invasive alternative, particularly for lung biopsies in patients with interstitial lung disease (ILD) and impaired respiratory function. This study aims to investigate the benefits of non-intubated surgery on postoperative respiratory function and to compare operative outcomes between intubated VATS (IVATS) and NIVATS.</p><p><strong>Methods: </strong>We conducted a single-centre retrospective study of patients who underwent lung biopsy for ILD diagnosis via VATS between January 2020 and September 2023 at Montpellier University Hospital. Primary outcomes included the variation in pulmonary function tests after surgery (FEV<sub>1</sub>, FVC, DLCO). Secondly, this study compares clinical postoperative outcomes and diagnostic yield between the two groups.</p><p><strong>Results: </strong>The study included 61 patients, with 42% (n = 26) undergoing NIVATS. The NIVATS group showed a significantly smaller decrease in postoperative FEV<sub>1</sub> and FVC compared to the IVATS group (p = 0.001 for both variables). Additionally, NIVATS was associated with shorter operating room time (247 min vs. 288 min, p = 0.013), reduced hospital stay duration (47.5 h vs. 65.2 h, p = 0.018), and decreased need for additional analgesics (3% vs. 15%, p = 0.001). Diagnostic yield was at least similar to IVATS. There were no significant differences in DLCO or chest tube duration between the two groups.</p><p><strong>Conclusions: </strong>NIVATS offers better preservation of respiratory function, a good diagnostic yield, and improved overall outcomes following surgical lung biopsy in patients with ILD and could be a preferred technique for diagnosis.</p>","PeriodicalId":21129,"journal":{"name":"Respirology","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}