International Journal of Academic Medicine and Pharmacy最新文献_第4页

Elevated PAPP-A Levels In Patients With Obstructive Sleep Apnea Syndrome 阻塞性睡眠呼吸暂停综合征患者ppap - a水平升高

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.49302

F. Baylan, E. Yarar, Filiz Alkan, Baylan

{"title":"Elevated PAPP-A Levels In Patients With Obstructive Sleep Apnea Syndrome","authors":"F. Baylan, E. Yarar, Filiz Alkan, Baylan","doi":"10.29228/jamp.49302","DOIUrl":"https://doi.org/10.29228/jamp.49302","url":null,"abstract":": Aim of this study was to evaluate serum concentration of Pregnancy-Associated Placental Protein-A (PAPP-A) in obstructive sleep apnea syndrome (OSAS) and to examine the relationship of PAPP-A with disease severity and body mass index (BMI). 60 OSAS patients and 21 control subjects included. All study participants were evaluated with polysomnograpic data, BMI, serum lipid, insulin, glucose and PAPP-A levels.PAPP-A values were higher in OSAS group than control group. When the groups were examined according to apnea-hypopnea index (AHI), PAPP-A level of severe OSAS group was determined to be significantly higher than that of control and mild and moderate OSAS groups. As the severity of OSAS increased, the level of PAPP-A increased. In ROC analysis applied to PAPP-A levels of the OSAS and control groups, the optimum cut-off point for serum PAPP-A levels in this study population was 2.38 ng/ml. A positive correlation was determined between PAPP-A levels, BMI and insulin levels. PAPP-A could be a clinical marker for the risk of metabolic syndrome and cardiovascular events in OSAS. Since OSAS patients have a high risk of developing cardiovascular disease, it would be useful to assess prognostic data provided by PAPP-A.","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131649625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lazaroid U-74389G Decreases Testis Tissue Injury Induced by Testicular Torsion Detorsion: An Experimental Study Lazaroid U-74389G减轻睾丸扭转所致睾丸组织损伤的实验研究

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.43165

A. Tanyeli̇

引用次数: 1

Birinci Basamak Sağlık Çalışanlarında Mobbing ve İş Doyumu İlişkisi; Manisa Örneği

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.40220

S. Kara

引用次数: 0

The Importance of Pictograms in Pharmacy Practice 象形文字在药学实践中的重要性

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.49679

B. Kiran, Elif Gizem Karaca, Özgecan Gül Hızal

引用次数: 0

Hydroxychloroquine: New Perspectives for an Indispensable Old Drug 羟氯喹:一种不可或缺的老药的新视角

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.43388

S. Akarsu

{"title":"Hydroxychloroquine: New Perspectives for an Indispensable Old Drug","authors":"S. Akarsu","doi":"10.29228/jamp.43388","DOIUrl":"https://doi.org/10.29228/jamp.43388","url":null,"abstract":"Hydroxychloroquine (HCQ) is a multi-functional drug owing to its lysosomotropic, immunomodulatory, anti-inflammatory, anti-infective, antithrombotic, antitumoral (pronounced effects on autophagy and apoptosis processes) and beneficial metabolic properties (improved lipid profiles, decreased insulin resistance) We know that chronic low-dose HCQ therapy has been successfully used in a variety of chronic diseases such as rheumatological and dermatological disorders Additionally, with all these effects mentioned above and showing synergism, HCQ can also be useful mostly as an adjuvant in the management of many chronic metabolic disorders, serious life-threatening conditions such as cardiovascular, neurological, oncological and infectious diseases, as well as their accompanying morbidities More recently, this former drug, whose effectiveness has been shown in the global coronavirus disease 2019 (COVID-19) pandemic, has entered the spotlight again Ongoing clinical trials testing HCQ in new indications and challenging diseases are still receiving great attention In this article, the mechanisms of action, current clinical uses and new indications of HCQ therapy have been overviewed with a comprehensive literature review","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132646628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Variations of Total-Aeroallergen Specific IgE and Eosinophil Levels in Psoriasis 银屑病患者总气敏原特异性IgE和嗜酸性粒细胞水平的变化

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.45530

R. Güner

{"title":"Variations of Total-Aeroallergen Specific IgE and Eosinophil Levels in Psoriasis","authors":"R. Güner","doi":"10.29228/jamp.45530","DOIUrl":"https://doi.org/10.29228/jamp.45530","url":null,"abstract":"The aim of the present study was to investigate the predisposition to atopy in psoriasis vulgaris. Total serum immunoglobulin E (Ig E) and radioallergosorbent test (RAST) (Allergen-specific IgE Antibody test) were used in psoriasis patients in order to investigate this correlation. Forty-eight psoriasis patients and thirty-nine healthy control group were included in the study. Allergen-specific IgE antibody test for peripheral eosinophilia, serum total Ig E and Dermatophagoides (D.) pteronyssinus and D. farinae was applied to all the study group. The treatment, severity of the disease, age, gender, and the duration of the disease were taken into account in the patient group, no statistically significant difference was detected in terms of allergen-specific IgE antibody test for D. pteronyssinus and D. farinae (p>0.05). Serum IgE and eosinophil were seen at a higher rate in psoriasis patients (p < 0.05). Patients with psoriasis have elevated levels of serum eosinophil and serum total Ig E. Although there is no aeroallergen specific immune shift associated in relation to house dust mites, serum IgE and eosinophils may be important important in the course and follow-up of the disease.","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133291818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Learning Medical Terminology Facilitated with Visual Materials? 视觉材料有助于医学术语的学习吗?

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/JAMP.50146

Fatmanur Uysal

{"title":"Is Learning Medical Terminology Facilitated with Visual Materials?","authors":"Fatmanur Uysal","doi":"10.29228/JAMP.50146","DOIUrl":"https://doi.org/10.29228/JAMP.50146","url":null,"abstract":": The aim of this study was to observe the effects of visual materials with technology in anatomical terminology learning and short-and memorize. A total of 187 students enrolled and divided into two groups, 95 students (17.89± 0.06 years, 63 F, 32 M) were in group A and 92 students (17.94±0.05 years, 67 F, 25 M) were in group B. Group A received a document containing anatomic terms supported with visually (ex. pictures, shapes, cartoons) and Turkish meanings of terms, which uploaded to the phones of students. A text that contains anatomic terms and Turkish meanings of terms was given to students in Group B. Students studied these documents in their spare time. During semester three routine quizzes were conducted to the students. First exam was performed one week after documents were given, second exam was 1 month, and third exam was three months after. The content of all exams was the same. All exams were held without prior notice to assess learning skills and self-study request. There was a significant difference between three exams (p<0.001). Examination scores was significantly higher in second and third exam comparing with first exam. Also second exam score was significantly higher than third exam (p<0.001). There was a significant difference in examination scores between and within groups (p<0.001). Examination scores was significantly higher in group A than group B at three exams. The study shows that more visual education with technology can be a useful tool if well designed and integrated into current anatomy teaching methods and the curriculum.","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129489830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Inflammation on Obese Individuals and Patients Diagnosed with Type 2 Diabetes Mellitus 肥胖者与2型糖尿病患者炎症反应的比较

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.48736

H. Savaş, Ismail Sarikan

{"title":"Comparison of Inflammation on Obese Individuals and Patients Diagnosed with Type 2 Diabetes Mellitus","authors":"H. Savaş, Ismail Sarikan","doi":"10.29228/jamp.48736","DOIUrl":"https://doi.org/10.29228/jamp.48736","url":null,"abstract":": Obesity is expressed as increased body fat tissue mass. Obesity is the most frequent cause of insulin resistance. Insulin resistance leads to formation of type 2 diabetes mellitus within a period of 10-15 years. Due to this mechanism, there is a strong relationship between obesity and type 2 diabetes mellitus. This study aimed to compare obesity and type 2 diabetes mellitus, which occur with similar mechanisms, based on the inflammation they cause. Ninety-seven male and female individuals were included in the study. The participants were divided into three groups as the control group (n=31), obese group (n=33) and type 2 diabetes group (n=33). Their clinic bio-chemical tests were obtained retrospectively from their files and analyzed. The Neutrophil / Lymphocyte (N/L) ratios of the control, obese non-diabetic and type 2 diabetes mellitus groups were found respectively as (mean±SD) 1.76 ± 0.69, 1.95 ± 0.89 and 2.79 ± 2.16 (p=0.01). While N/L was numerically higher in the obese non-diabetic group in comparison to the control group, the difference was not statistically significant (p>0.05). This value was found to be significantly higher in the type 2 diabetes mellitus group than the other two groups (p<0.05). It is seen that type 2 diabetes mellitus development in obese non-diabetic individuals may be prevented by weight loss as a result of lifestyle changes, healthy and balanced diet, exercise and increased mobility, and this way, progression of systemic inflammation and formation of tissue and organ damage may be counteracted. In addition, if the transformation of insulin resistance into type 2 diabetes mellitus in obese individuals can be prevented, cardiovascular morbidity and mortality may decrease.","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116517353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Laboratory Results and Chest Computed Tomography Scans of COVID-19 Patients: A Pilot Study COVID-19患者的实验室结果和胸部计算机断层扫描的比较:一项初步研究

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.49402

M. Etli, N. Kozaci, S. Avnioglu

{"title":"Comparison of Laboratory Results and Chest Computed Tomography Scans of COVID-19 Patients: A Pilot Study","authors":"M. Etli, N. Kozaci, S. Avnioglu","doi":"10.29228/jamp.49402","DOIUrl":"https://doi.org/10.29228/jamp.49402","url":null,"abstract":"In this article, we aimed to investigate lung involvement in patients suffering from the new Coronavirus Disease 2019 (COVID-19) and to determine laboratory markers that indicate lung involvement. Patients diagnosed with COVID-19 pneumonia were included 90 patient in Group 1, while Group 2 comprised 60 patients in the control group and total of 150 patient. CCT scans of the study patients were transferred to the Intrasense Myrian® software (Myrian;Intrasense, Montpellier, France) and 3D models of the data were generated. Mean levels of D-dimer, fibrinogen and C-reactive protein (CRP) in Group 1 were 515±958 μg/L, 467±182 mg/dL and 5.67±5.46 mg/dL, respectively, whereas those in Group 2 were 129±120 μg/L, 345±113 mg/dL and 1.32±2.58 mg/dL, respectively (P<0.001). Right lung volume (RLV), left lung volume (LLV) and total lung volume (TLV) of Group 1 patients were 2419±554 cm3, 1857±634 cm3 and 3929±1297 cm3, respectively, while those measurements in Group 2 were 2483±503 cm3, 2118±535 cm3 and 4538±1079 cm3, respectively (P<0.001). Reduction of total lung volumes correlates with increase in levels of D-dimer and CRP and decrease in lymphocyte counts. Lung volumes of patients who develop Covid-19 pneumonia decrease. D-dimer, CRP and fibrinogen levels increase and lymphocyte levels decrease in these patients.","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127444088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pseudoxanthoma Elasticum and Calcinosis Cutis 弹性假黄色瘤和皮肤钙质沉着症

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.42889

R. Güner

引用次数: 0