International Journal of Academic Medicine and Pharmacy最新文献_第5页

Neovascular Glaucoma – A Review 新生血管性青光眼的研究进展

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.43760

Armağan Filik, Özen Osmanbaşoğlu

{"title":"Neovascular Glaucoma – A Review","authors":"Armağan Filik, Özen Osmanbaşoğlu","doi":"10.29228/jamp.43760","DOIUrl":"https://doi.org/10.29228/jamp.43760","url":null,"abstract":"Neovascular glaucoma (NVG) is a severely blinding disease with high intraocular pressure (IOP) resistant to treatment. The main problem in NVG is the release of vascular endothelial growth factor (VEGF) due to retinal ischemia caused by the underlying disease. Both the underlying disease and intraocular pressure should be treated in management of patients with NVG. The purpose of this review is to discuss etiology, pathogenesis, clinic classification and management of NVG. The main purpose in NVG management is to prevent the development of NVG by treating the underlying cause mainly proliferative diabetic retinopathy (PDR), central retinal vein occlusion (CRVO) and ocular ischemic syndrome (OIS). If NVG has developed, then it will be necessary to both treat the underlying etiology and high intraocular pressure. Panretinal photocoagulation (PRP) and anti -VEGF drugs are important in the treatment of NVG. Anti-glaucomatous drugs that reduce the production of aqueous are used in medical treatment in the control of IOP. Medical treatment may be insufficient in the control of IOP. Surgical methods will be required when IOP is not controlled by medical therapy. Fibrosis that develop after trabeculectomy and tube shunt surgeries reduces the success of surgery. Applying preoperative anti-VEGF may increase the rate of surgical success. Cyclodestructive procedures should be preferred when other surgical methods fail and patients with poor visual prognosis.","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127171837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of The Antiproliferative Effect of Camelia Sinensis on Liver Cancer (Hepg2) Cell Line 茶树对肝癌(Hepg2)细胞株抗增殖作用的研究

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.40233

Hale Yildiz- Gamze Tuzun, Sema Misir, Tutku Tunc, Ceyla Hepokur

引用次数: 0

A Cross-Sectional Study for Determining the Knowledge and Attitudes About Use of Antibiotics in A Rural Area 某农村地区抗生素使用知识和态度的横断面调查

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.43223

Seyfi Durmaz, Safiye Özvurmaz, A. Mandıracıoğlu

{"title":"A Cross-Sectional Study for Determining the Knowledge and Attitudes About Use of Antibiotics in A Rural Area","authors":"Seyfi Durmaz, Safiye Özvurmaz, A. Mandıracıoğlu","doi":"10.29228/jamp.43223","DOIUrl":"https://doi.org/10.29228/jamp.43223","url":null,"abstract":"According to the data of 2015, Turkey ranks first among the OECD countries in infections resistant to antibiotics. The efforts of preventing unprescribed antibiotic use as being implemented in Turkey so far since 2016 may have shaped this relationship. The purpose of the study is to determine knowledge level of the adults living in a rural neighborhood close to Aydın about antibiotics and antibiotic resistance, and their statuses regarding their use. This cross-sectional study was conducted in Aydın. Data were collected from 411 participants. 26 questions were used for the questionnaire. Knowledge-attitude level was determined with average of the number of correct answers given in the survey. Sociodemographic variables and the variables consisting pharmaceutical use variables were defined as independent variable. Linear regression analysis by SPSS 23.0 was for analysis of the data. Simple linear regression outputs were shown as Model 1, and outputs of the multiple linear regression analysis were shown by Model 2. Internal consistency Kuder-Richardson 20 reliability coefficient was calculated. It was determined that self-medication of antibiotics was too low as a result of restriction of unprescribed antibiotic use by the public. It was understood that those using prescribed antibiotics and receiving information from physicians had more knowledge about antibiotics. Having received high school and higher education increased the participants' knowledge-attitude level by 1.88 (1.13-2.64) points, having lived in a city in childhood increased it by 1.07 (0.32-1.82) points, having used antibiotic within the last one month increased it by 1.12 (0.30-1.94) points, and the fact the last used antibiotic is prescribed by doctor increased it by 2.99 (1.17-4.81) points. There may be need for a training program which would generalize the \"one health\" approach that would provide the opportunity to guide rational antibiotic use in both humans and animals.","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128838111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hatay İlimizden İzole Edilen Kutanöz Leishmania Suşlarının İzolasyonu ve Biyobank (Kriyobank) Oluşturulması

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.48513

-. T. K. -. G. Ç. -. N. Özpınar

引用次数: 0

PC-3 İnsan Prostat Kanser Hücre Hattı Üzerine [1-(2-Metil-2-Propenil)-3-(2-Metilbenzil)Benzimidazolyum Klorür Ligandı ve Bu Ligandın Gümüş(I) Kompleksinin Sitotoksik Aktivitesi

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.49540

-. G. E. -. S. Ş. -. N. Şahin

引用次数: 0

The Effect of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy on Quality of Life in Colorectal Originated Peritoneal Carcinomatosis 细胞减缩手术及腹腔内高温化疗对结直肠源性腹膜癌患者生活质量的影响

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.47767

M. Bostancı, K. Karadayi, Meriç Emre, Bostanci

{"title":"The Effect of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy on Quality of Life in Colorectal Originated Peritoneal Carcinomatosis","authors":"M. Bostancı, K. Karadayi, Meriç Emre, Bostanci","doi":"10.29228/jamp.47767","DOIUrl":"https://doi.org/10.29228/jamp.47767","url":null,"abstract":": In this study, it was aimed to determine the symptoms experienced by patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy due to peritoneal carcinomatosis caused by colorectal cancer and the areas where their quality of life is affected. This study was carried using QLQ C30 and QLQ C29 form, out with patients who underwent SRC+HIPEC due to colorectal cancer in Cumhuriyet University Surgical Oncology Clinic. The QLQ-C30 quality of life scale is a globally used scale for patients with cancer. The scale consists of 30 questions for the past week. QLQ-CR29 is a quality of life questionnaire specifically designed for colorectal cancer. It consists of 29 questions evaluating disease symptoms, treatment side effects, body image, sexual status, and future prospects. The mean scores of the patients from the EORTC QLQ-C30 quality of life scale sub-dimensions; the general health score is 8.49 ± 2.54 functional scale 31.80 ± 2.18 and symptom scale 34.20 ± 3.32. When the ranking of the items in the QLQ-C30 scale according to their average scores is examined, the antecedents of vomiting, need for rest, financial difficulty, difficulty while walking for long and feeling fatigue are the predecessors that received the most average, respectively. When the ranking of the items on the QLQ-C29 scale according to their average scores is examined, frequent urination during the night, pain in the anal area, mucus in bowel movements, hair loss are the predecessors that received the most average, respectively. Although aggressive surgery is performed in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy, side effects and loss of function do not reduce the quality of life of patients. As a result of multidisciplinary studies, we believe that more progress will be made in improving the quality of life of patients.","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117264631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Cold Application and Heparinoid on Periorbital Edema and Ecchymosis After Craniotomy: A Randomized Controlled Clinical Trial 冷敷和类肝素对开颅术后眶周水肿和瘀斑的影响:一项随机对照临床试验

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.42834

Serpil Yüksel Neriman Akyolcu

{"title":"Effect of Cold Application and Heparinoid on Periorbital Edema and Ecchymosis After Craniotomy: A Randomized Controlled Clinical Trial","authors":"Serpil Yüksel Neriman Akyolcu","doi":"10.29228/jamp.42834","DOIUrl":"https://doi.org/10.29228/jamp.42834","url":null,"abstract":"This study was performed to determine the effect of cold application and heparinoid cream on periorbital edema and ecchymosis after craniotomy. The sample of this prospective parallel-arm, randomized controlled trial included 90 neurosurgical patients who underwent anterior craniotomy in two medical faculty hospitals of a university in Turkey. The patients were randomly assigned (1:1:1) to the cold application, heparinoid or control groups. Those patients in the cold application group received cold application with gel pack on their periorbital areas for 20 minutes per hour for three days beginning from the 3 rd hour following craniotomy. On the other hand, the patients in the heparinoid group received heparinoid cream on their periorbital areas once at the 3 rd and 9 th hours after craniotomy and then four times/day at 6-hour intervals for three postoperative days. Periorbital edema and ecchymosis were evaluated for three days after craniotomy using Kara & Gökalan’s scale by blinded observers. In all the measurements after craniotomy, except for those at the 3 rd hour, the periorbital edema score of the cold application group was significantly lower than those of both the heparinoid and control groups (p<0.001). The upper and lower eyelid ecchymosis scores of the cold application group were significantly lower than those of both the heparinoid and control groups on the 1 st , 2 nd and 3 rd days after craniotomy (p<0.001). In the cold application group, periorbital edema score decreased significantly as the skin temperature decreased only on the 3 rd day after craniotomy (p=0.01). The study revealed that cold application and heparinoid cream administered for three days beginning from the 3 rd hour after craniotomy did not prevent postoperative periorbital edema and ecchymosis, but cold application significantly reduced periorbital edema and ecchymosis.","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126617851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Evaluation of Hallux Valgus Deformity among Medical Student : A Cross-Sectional Study 医学生拇外翻畸形的评估:一项横断面研究

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.45553

K. Karacan, M. Erdoğan

{"title":"Evaluation of Hallux Valgus Deformity among Medical Student : A Cross-Sectional Study","authors":"K. Karacan, M. Erdoğan","doi":"10.29228/jamp.45553","DOIUrl":"https://doi.org/10.29228/jamp.45553","url":null,"abstract":"Hallux valgus (HV) deformity is one of the most prevalent orthopedic foot disorders in the world; It occurs as a result of the lateral deviation of the great toe and medial deviation of metatarsophalangeal joint I (MTP). Many factors such as neuromuscular diseases, familial transition, wrong shoe choice and systemic diseases play a role in HV etiology. The treatmalet and follow-up process of HV, which has negative effects on walking and quality of life when not treated, varies in different populations. The aim of our study is to determine the rate of HV in the young population and to determine the effect of factors such as wrong shoe choice and excess body weight. We conducted measuremalets on 300 students (120 male, 180 female) studying at the Faculty of Medicine of Sakarya University. The average age of the students was found to be 19.87 ± 1.55 (ss). Percentages of students' right foot HV angles; While 94 % mild type HV angle was determined as 6 % moderate type HV angle, severe type HV angle was not found in both sexes. According to the results of the study, it was concluded that that the pain intensity and loss of function related to HV were higher in female depending on the shoe preference. Surgical treatmalet of HV affects the physical appearance of individuals as well as negatively affects quality of life due to pain and loss of function, is a difficult process. Therefore, conservative treatmalet should be the primary choice. Careful evaluation of social parameters that are part of conservative treatmalet; will contribute positively to physicians and physiotherapists.","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125224197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biocompatibility of Two Different Universal Adhesives 两种不同的通用粘合剂的生物相容性

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.43624

Derya Sürmelioğlu Ceylan Hepokur, Sevim Atılan Yavuz

{"title":"Biocompatibility of Two Different Universal Adhesives","authors":"Derya Sürmelioğlu Ceylan Hepokur, Sevim Atılan Yavuz","doi":"10.29228/jamp.43624","DOIUrl":"https://doi.org/10.29228/jamp.43624","url":null,"abstract":"The aim of this study is to evaluate the cytotoxicity with agar diffusion test of two different universal adhesive systems with different content, pH, and polymerization techniques on mouse fibroblast cell lines (L929). G-Premio Bond (GC Europe, Belgium) and Tokuyama Universal Bond (Tokuyama, USA) were supplied from common universal adhesive systems. G-Premio Bond, which is light-polymerized, and Tokuyama Universal Bond adhesive systems, which are chemical-polymerized, are polymerized according to the manufacturer's instructions. All materials were incubated for 72 hours in Dulbecco's modified Eagle medium (DMEM) solution. L929 cells were placed in each wells to be 1.5x10 5 cells / ml and adhesive systems to be examined for cytotoxicity were applied. Waiting for the added agar to freeze, adhesive systems were installed and cell viability examined in an inverted microscope. Waiting for the added agar to freeze, adhesive systems were placed and cell viability examined in an inverted microscope. Statistical analysis was performed using one-way analysis of variance (ANOVA) and Tukey’s post-hoc test. A statistically significant difference was found between the two different Universal adhesive systems in terms of cell viability values. Cell viability was significantly lower in the Tokuyama Universal Bond group compared to the G-Premio Bond group (p <0.05). In treatments using universal adhesive systems, cytotoxic effects can be observed against live cells. The compatibility of the results should be supported by different cytotoxicity detection methods.","PeriodicalId":210978,"journal":{"name":"International Journal of Academic Medicine and Pharmacy","volume":"585 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116308926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extragenital Lichen Sclerosus and Vitiligo: A Rare Association 外阴硬化地衣和白癜风:一种罕见的联系

International Journal of Academic Medicine and Pharmacy Pub Date : 1900-01-01 DOI: 10.29228/jamp.42760

Ö. Kaya

引用次数: 0