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Triterpenoids and Pharmacological Activities from Kadsura (Schisandraceae) were gathered from 1987 to 2022 从1987年到2022年收集了南五味子的三萜类化合物和药理活性
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-12-17 DOI: 10.25135/rnp.373.2209.2588
Xiaomei Song, Haonan Xu, Yuanyuan Liu, Chenwang Liu, Chong Deng, Yi Jiang, Yu-ze Li, Dongdong Zhang, Wei Wang
{"title":"Triterpenoids and Pharmacological Activities from Kadsura (Schisandraceae) were gathered from 1987 to 2022","authors":"Xiaomei Song, Haonan Xu, Yuanyuan Liu, Chenwang Liu, Chong Deng, Yi Jiang, Yu-ze Li, Dongdong Zhang, Wei Wang","doi":"10.25135/rnp.373.2209.2588","DOIUrl":"https://doi.org/10.25135/rnp.373.2209.2588","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44545372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-inflammatory Benzofurans from the Heartwood of Dalbergia cochinchinensis Pierre ex Laness 南美白黄檀心材中的抗炎苯并呋喃类化合物
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-12-17 DOI: 10.25135/rnp.371.2210.2594
Qiwan Zheng, Ronghua Liu, Lanying Chen, Canyue Quyang, Xianwen Wei, Yang Liu, Jiahui Ren
{"title":"Anti-inflammatory Benzofurans from the Heartwood of Dalbergia cochinchinensis Pierre ex Laness","authors":"Qiwan Zheng, Ronghua Liu, Lanying Chen, Canyue Quyang, Xianwen Wei, Yang Liu, Jiahui Ren","doi":"10.25135/rnp.371.2210.2594","DOIUrl":"https://doi.org/10.25135/rnp.371.2210.2594","url":null,"abstract":": A new benzofuran, Cochinfuran A ( 1 ), and four known benzofurans ( 2-5 ) were isolated from the heartwood of Dalbergia cochinchinensis Pierre ex Laness. The chemical structure of the new benzofuran was determined based on broad NMR and mass spectrometry evaluation. Bioactivity assays showed that the compounds 1 - 3 and 5 were found as anti-inflammatory agents with IC 50 values 49.01 ± 1.54, 1368.93 ± 0.98, 67.48 ± 0.92 and 77.91 ± 1.53 μM, respectively. They could reduce the production of NO ( P <0.001) with 3.52~7.04, 1.96~7.84, 1.85~7.40 and 0.98~3.93 μM and restrained LDH ( P <0.01) with 3.52~7.04, 3.93~7.84, 3.70~7.40 and 0.98~3.93 μM in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages, respectively, the compound 4 (IC 50 218.20 ± 3.39 μM) showed no anti-inflammatory activity","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42654579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two New Sesquiterpenoids from Kalimeris shimadae 岛马兰中两个新的倍半萜类化合物
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-12-13 DOI: 10.25135/rnp.369.2210.2604
Guo-Kai Wang, Yun-peng Sun, Yu-fei Huang, Yang Yu, Jai-Sing Yang, Jin-Song Liu
{"title":"Two New Sesquiterpenoids from Kalimeris shimadae","authors":"Guo-Kai Wang, Yun-peng Sun, Yu-fei Huang, Yang Yu, Jai-Sing Yang, Jin-Song Liu","doi":"10.25135/rnp.369.2210.2604","DOIUrl":"https://doi.org/10.25135/rnp.369.2210.2604","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43788451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Phenolic Compounds by LC-HRMS and Determination of Antioxidant and Enzyme Inhibitory Properties of Verbascum speciousum Schrad LC-HRMS法分析酚类化合物及石藻抗氧化和酶抑制性能的测定
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-12-13 DOI: 10.25135/rnp.370.2210.2598
I. Gülçin, Hatice Kiziltaş, Zeynebe Bi̇ngöl, A. Gören, S. Alwasel
{"title":"Analysis of Phenolic Compounds by LC-HRMS and Determination of Antioxidant and Enzyme Inhibitory Properties of Verbascum speciousum Schrad","authors":"I. Gülçin, Hatice Kiziltaş, Zeynebe Bi̇ngöl, A. Gören, S. Alwasel","doi":"10.25135/rnp.370.2210.2598","DOIUrl":"https://doi.org/10.25135/rnp.370.2210.2598","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46662372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Eupalinolide N, a Previously Undescribed Sesquiterpene Lactone with Anti-inflammatory Activity from Eupatorium lindleyanum 从紫泽兰中发现的一种具有抗炎活性的倍半萜内酯
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-12-13 DOI: 10.25135/rnp.368.2206.2499
Cheng Peng, Jie Yan, D. Guo, Jin Pei, Yun Deng, Ding Liu, Xiaofang Xie, Wenxiu Guo, Lanyu Zhou, Bin Xiao, Xue-yan Huo, Yunjie Hu
{"title":"Eupalinolide N, a Previously Undescribed Sesquiterpene Lactone with Anti-inflammatory Activity from Eupatorium lindleyanum","authors":"Cheng Peng, Jie Yan, D. Guo, Jin Pei, Yun Deng, Ding Liu, Xiaofang Xie, Wenxiu Guo, Lanyu Zhou, Bin Xiao, Xue-yan Huo, Yunjie Hu","doi":"10.25135/rnp.368.2206.2499","DOIUrl":"https://doi.org/10.25135/rnp.368.2206.2499","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41465398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diterpenoids from the Seeds of Euphorbia Lathyris and their Cytotoxic Acitivity 大戟种子中的二萜类化合物及其细胞毒活性
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-11-26 DOI: 10.25135/rnp.365.2205.2459
Na Liu, Yajie Sun, Yulin Sun, Yilin Sun, Ting Luo, Fengying Yang, Peng Wang, Di Ge
{"title":"Diterpenoids from the Seeds of Euphorbia Lathyris and their Cytotoxic Acitivity","authors":"Na Liu, Yajie Sun, Yulin Sun, Yilin Sun, Ting Luo, Fengying Yang, Peng Wang, Di Ge","doi":"10.25135/rnp.365.2205.2459","DOIUrl":"https://doi.org/10.25135/rnp.365.2205.2459","url":null,"abstract":": A total of 23 diterpenoids were isolated from the seeds of Euphorbia lathyris , and one new compound ( 1 ) and twenty-two known compounds ( 2-23 ) were characterized by using 1D- and 2D-NMR spectra and HRESIMS analysis. Cytotoxicity of the isolated compounds against BT-549 and MDA-MB-231 cancer cells lines were evaluated further. Compounds 3 , 10 , 14 , and 22 were found to exhibit considerable cytotoxic activities against BT-549 cells, with IC 50 values ranging from 4.7 to 10.1 μM. Compounds 1 , 2 , 14 and 22 were able to inhibit the MDA-MB-231 cell line growth with IC 50 values of 5.7 to 21.3 μM, while other compounds showed no obvious inhibitory effects.","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47346277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Essential Oil Compositions and Antimicrobial Activity of the Leaves of Alphonsea monogyma Merr. & Chun and Goniothalamus banii B. H. Quang, R. K. Choudhary & V.T. Chinh from Vietnam 山Alphonsea monogyma Merr.&来自越南的Chun和Goniothalamus banii B.H.Quang，R.K.Choudhary和V.T.Chinh
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-11-26 DOI: 10.25135/rnp.367.2208.2547
I. Ogunwande, L. Huong, L. Giang, D. Dai
{"title":"Essential Oil Compositions and Antimicrobial Activity of the Leaves of Alphonsea monogyma Merr. & Chun and Goniothalamus banii B. H. Quang, R. K. Choudhary & V.T. Chinh from Vietnam","authors":"I. Ogunwande, L. Huong, L. Giang, D. Dai","doi":"10.25135/rnp.367.2208.2547","DOIUrl":"https://doi.org/10.25135/rnp.367.2208.2547","url":null,"abstract":": Essential oils from the leaves of Alphonsea monogyma Merr. & Chun and Goniothalamus banii B. H. Quang, R. K. Choudhary & V.T. Chinh from Vietnam were obtained by hydrodisitllation and the chemical components determined by gas chromatography (GC) and gas chromatography coupled with mass spectrometry (GC/MS). The antimicrobial assay was conducted by microdilution broth method. The respective yields of the essential oils were 0.18% (v/w) and 0.355% (v/w), respectively. The major components of A. monogyma were ( E )-caryophyllene (13.8%),  -cadinene (12.5%), bicyclogermacrene (12.4%), cis -β-elemene (12.1%), and germacrene D (11.4%). However, myrcene (47.1%), α-pinene (9.7%) and ( E )-caryophyllene (9.1%) were the dominant constituents of the essential oil of G. banii . The leaf essential oil of A. monogyma displayed potent antimicrobial activity towards the Gram-positive microorganisms of Enterococcus faecalis ATCC29212, Staphylococcus aureus ATCC25923 and Bacillus cereus ATCC14579 with minimum inhibitory concentration (MIC) values of 2.23 µg/mL, 10.45 µg/mL and 10.33 µg/mL, respectively. On the other hand, essential oil from G. banii exhibited the most effective antibacterial against Gram-negative Pseudomonas aeruginosa ATCC27853 (MIC 5.67 µg/mL), and anti-candidal action towards Candida albicans ATCC10231 (MIC 32.67 µg/mL). The chemical constituents and antimicrobial activity of the essential oils of A. monogyma and G. banii were being reported for the first time.","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43118826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparative Analyses on Chemical Constituents and Biological Activities of Laserpitium siler L. from Serbia 塞尔维亚激光鹿的化学成分和生物活性的比较分析
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-11-25 DOI: 10.25135/rnp.364.2207.2528
Ksenija S. Mileski, A. Ćirić, U. Gašić, Lazar D. Žarković, Z. Krivošej, A. Džamić
{"title":"Comparative Analyses on Chemical Constituents and Biological Activities of Laserpitium siler L. from Serbia","authors":"Ksenija S. Mileski, A. Ćirić, U. Gašić, Lazar D. Žarković, Z. Krivošej, A. Džamić","doi":"10.25135/rnp.364.2207.2528","DOIUrl":"https://doi.org/10.25135/rnp.364.2207.2528","url":null,"abstract":": The traditional European medicinal plant Laserpitium siler L. was studied for the first time for the chemical composition and in vitro biological potential of extracts from fruits and aerial parts. Eight extracts were subjected to spectrophotometric detection and LC-MS quantification of phenolics. The bioactivity assessment comprised antioxidant, antimicrobial, anti-denaturation, acetylcholinesterase, tyrosinase, α-amylase, and α-glucosidase inhibition assays. The spectrophotometric analyses showed that the alcoholic extracts contained the most phenolic acids and coumarins. Among the twenty quantified compounds in the methanolic extracts, chlorogenic acid (29.10 mg/kg in the fruits; 47.00 mg/kg in the aerial parts) and p -coumaric acid (7.50 mg/kg in the fruits; 9.50 mg/kg in the aerial parts) were the most abundant. The DPPH/ABTS/BBT tests showed the strongest antioxidant effect of the methanolic extract of the aerial parts. The results of the microdilution assay referred to stronger antibacterial than antifungal activity, with the essential oil being as effective as the antibiotics used. The extracts expressed promising activity against P . aeruginosa PAO1 biofilm formation and pyocyanin synthesis. The prevention of BSA denaturation by the ethanolic extracts was comparable to diclofenac (91.08%-fruits, 95.08%-aerial parts, and 95.60%-diclofenac). IC 50 values showed greater enzyme inhibitory potential of aerial parts and the highest reduction of α-glucosidase activity.","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45884088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Anti-inflammatory Continents from the Heartwood of Dalbergia melanoxylon 黑檀心材中的抗炎成分
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-11-08 DOI: 10.25135/rnp.366.2208.2560
Qing Zhu, C. Ouyang, Yang Liu, Zhangjun Xu, Ying Zhang, Ronghuai Liu, Lanying Chen
{"title":"Anti-inflammatory Continents from the Heartwood of Dalbergia melanoxylon","authors":"Qing Zhu, C. Ouyang, Yang Liu, Zhangjun Xu, Ying Zhang, Ronghuai Liu, Lanying Chen","doi":"10.25135/rnp.366.2208.2560","DOIUrl":"https://doi.org/10.25135/rnp.366.2208.2560","url":null,"abstract":": A new chalcone compound, methyl 5-cinnamoyl-2-hydroxy-4-methoxybenzoate ( 1 ), and a new cinnamylphenol compound, methyl 3-cinnamyl-5-hydroxy-4-methoxybenzoate ( 2 ) together with four known compounds ( 3 - 6 ) were isolated from the CH 2 Cl 2 fraction of Dalbergia melanoxylon . Their structures were elucidated by comprehensive spectral measurements including NMR techniques, mass spectrometry, single crystal X-ray diffraction and, together with comparison of the literature data. According to the determination results of compound 1 and 2 on RAW 264.7 cell viability, the IC 50 values of compounds were found to be 3.2 and 383.8 μM, respectively. Compared with LPS model group, compounds 1 and 2 were found to be significantly reduce the release of NO in the concentration ranges of 1.2~9.6 and 33.7 μM ( P <0.01), and significantly inhibit the secretion of LDH in the range of 4.8~9.6 and 16.8~33.7 μM . melanoxylon cinnamylphenol; activity. © 2022 ACG","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47938929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Editorial 社论
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-10-29 DOI: 10.25135/rnp.389.2210.2400
M. Öztürk, Ahmet C. Gören
{"title":"Editorial","authors":"M. Öztürk, Ahmet C. Gören","doi":"10.25135/rnp.389.2210.2400","DOIUrl":"https://doi.org/10.25135/rnp.389.2210.2400","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44476165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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