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Sesquiterpenes from theLeaves of Dalbergia odorifera 降香降香叶中的倍半萜类化合物
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-07-28 DOI: 10.25135/rnp.347.2205.2466
C. Shen, Ronghua Liu, Lanying Chen, C. Ouyang, Ying Zhang, Qing Zhu
{"title":"Sesquiterpenes from theLeaves of Dalbergia odorifera","authors":"C. Shen, Ronghua Liu, Lanying Chen, C. Ouyang, Ying Zhang, Qing Zhu","doi":"10.25135/rnp.347.2205.2466","DOIUrl":"https://doi.org/10.25135/rnp.347.2205.2466","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47433796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The First Example of Di--Methane Rearrangement in Nature: Cephalotanols A and B, Two Novel Rearranged Norlignan Glycosides from Cephalotaxus fortunei Hook 自然界中二--甲烷重排的第一个例子:头藻醇A和B，两种新的重排头藻脂苷
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-07-28 DOI: 10.25135/rnp.345.2205.2461
Jin-Biao Xu, Xiaohui Xie, Qingqing Zhou, Yanting Zhou
{"title":"The First Example of Di--Methane Rearrangement in Nature: Cephalotanols A and B, Two Novel Rearranged Norlignan Glycosides from Cephalotaxus fortunei Hook","authors":"Jin-Biao Xu, Xiaohui Xie, Qingqing Zhou, Yanting Zhou","doi":"10.25135/rnp.345.2205.2461","DOIUrl":"https://doi.org/10.25135/rnp.345.2205.2461","url":null,"abstract":": A pair of unique diastereoisomers of norlignan glycosides named cephalotanols A ( 1 ) and B ( 2 ), together with two known compounds, have been isolated from the twigs and leaves of Cephalotaxus fortunei Hook. Their structures were elucidated by using a combination of spectroscopic techniques and comparison of experimental and calculated electronic circular dichroism (ECD) data. To our knowledge, cephalotanols A and B represent the first rearranged norlignan glycosides with diphenylvinylcyclopropane core found in natural sources, of which biosynthetic pathways originating from co-occurring precursors 3 S -4  - O -  - D - glucopyranosylhinokiresinol ( 3 ) and 3 S -4  - O -  - D -glucopyranosylhinokiresinol ( 4 ) via di-  -methane rearrangement is proposed.","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":"30 11","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41246221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Myrrhalindenane C, a New Eudesmane Sesquiterpenoid From Lindera Myrrha Roots 没药烯烯C，一种新的没药根倍半萜类化合物
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-07-25 DOI: 10.25135/rnp.343.2203.2396
T. Duong, Hoang-Dung Nguyen, H. T. Nguyen, T. Nguyen, Ngoc‐Hong Nguyen, Huu-Hung Nguyen, J. Sichaem
{"title":"Myrrhalindenane C, a New Eudesmane Sesquiterpenoid From Lindera Myrrha Roots","authors":"T. Duong, Hoang-Dung Nguyen, H. T. Nguyen, T. Nguyen, Ngoc‐Hong Nguyen, Huu-Hung Nguyen, J. Sichaem","doi":"10.25135/rnp.343.2203.2396","DOIUrl":"https://doi.org/10.25135/rnp.343.2203.2396","url":null,"abstract":": Phytochemical investigation of Lindera myrrha roots growing in Vietnam afforded a new eudesmane sesquiterpenoid, myrrhalindenane C ( 1 ), along with seven known compounds, rel -5-(3 S ,8 S -dihydroxy-1 R ,5 S -dimethyl-7-oxa-6-oxobicyclo[3,2,1]-oct-8-yl)-3-methyl-2 Z ,4 E -pentadienoic acid ( 2 ), 1- O -(4-hydroxy-2,6-dimethoxyphenoxy)-6- O -[ rel -5-(3 S ,8 S -dihydroxy-1 R ,5 S -dimethyl-7-oxa-6-oxobicyclo[3,2,1]-oct-8-yl)-3-methyl-2 Z ,4 E -pentadienoyl]-β-D-glucopyranose ( 3 ), curcumin ( 4 ), demethoxycurcumin ( 5 ), bisdemethoxycurcumin ( 6 ), (1 E ,6 E )-1,7-bis(4-methoxyphenyl)-1,6-heptadiene-3,5-dione ( 7 ), and sanjoseolide ( 8 ). The structures were determined by analysis of their MS and NMR data as well as by comparison with literature values. All compounds were evaluated for antimicrobial activity against antibiotic-resistant, pathogenic bacteria Enterococcus faecium, Staphylococcus aureus , and Acinetobacter baumannii . Publications. All rights reserved.","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45710175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two New Disaccharide Glycosides from the Root Cortex of Paeonia ostii 芍药根皮中两种新的二糖苷
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-07-25 DOI: 10.25135/rnp.342.2206.2475
Feng-qing Xu, De-Peng Wu, Lei Sun, Chui-Jian Kong, Huan Zhao
{"title":"Two New Disaccharide Glycosides from the Root Cortex of Paeonia ostii","authors":"Feng-qing Xu, De-Peng Wu, Lei Sun, Chui-Jian Kong, Huan Zhao","doi":"10.25135/rnp.342.2206.2475","DOIUrl":"https://doi.org/10.25135/rnp.342.2206.2475","url":null,"abstract":": Two new glycosides 2-hydroxy-4-methoxy-acetophenone-3- O -[ β -D-apiofuranosyl (1→6)- β -D-glucoside ( 1 ) and 4-hydroxy-2- O-β -rutinosyl acetophenone ( 2 ), along with two known compounds, paeonolide ( 3 ), involcranoside B ( 4 ) were isolated from the roots of Paeonia ostii . In addition, compound 4 was isolated from this genus for the first time. Their structures were established on the basis of spectral and chemical evidence. All the compounds showed inactive nitric oxide (NO) inhibitory effects.","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43071866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lactones from Glomerella cingulata Cultivated in Rice:Structural Studies and Antimicrobial Evaluation 水稻栽培扣带球菌内酯的结构研究及抗菌性能评价
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-07-17 DOI: 10.25135/rnp.340.2202.2352
Nayara F. Gomes, Manoel Leão L. Júnior, Antônio José C. Filho, Lourivaldo S. Santos, Luís Cláudio N. Silva, E. Rodrigues-Filho
{"title":"Lactones from Glomerella cingulata Cultivated in Rice:Structural Studies and Antimicrobial Evaluation","authors":"Nayara F. Gomes, Manoel Leão L. Júnior, Antônio José C. Filho, Lourivaldo S. Santos, Luís Cláudio N. Silva, E. Rodrigues-Filho","doi":"10.25135/rnp.340.2202.2352","DOIUrl":"https://doi.org/10.25135/rnp.340.2202.2352","url":null,"abstract":": Extracts of the endophytic fungus Glomerella cingulata grown in polish rice, were fractionated by chromatographic procedures including preparative scale HPLC. The isolated compounds were structurally elucidated through spectroscopic analysis, mainly 1 H and 13 C NMR and HRMS. These analyzes allowed the identification of pestalotin-1 ( 1 ) and the phthalides (3R*,8S*)-5,7-dihydroxy-3-(1-hydroxyethyl)-phthalide ( 2 ) and (3R*,8R*)-5,7-dihydroxy-3-(1-hydroxyethyl)-phthalide ( 3 ). The extracts, their fractions and isolated substances were tested against several bacteria. The lactone 2 showed some activity against lineages of E. coli and Enterococcus faecalis while its diastereomer 3 and pestalotin-1 were inactive","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46267592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Acyclic Diterpene from Bornean Local Red Chilli Pepper Capsicum frutescens L. 婆罗洲地方红辣椒中的新型无环二萜。
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-07-14 DOI: 10.25135/rnp.339.2204.2443
C. Vairappan, Kazuki Tani, Rolinus Paulous, Norhidayah Tumiran
{"title":"Novel Acyclic Diterpene from Bornean Local Red Chilli Pepper Capsicum frutescens L.","authors":"C. Vairappan, Kazuki Tani, Rolinus Paulous, Norhidayah Tumiran","doi":"10.25135/rnp.339.2204.2443","DOIUrl":"https://doi.org/10.25135/rnp.339.2204.2443","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41332491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Lignan from Leaves of Ormosia xylocarpa 木脂素的一种新发现
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-07-11 DOI: 10.25135/rnp.338.2203.2386
Lin Ni, Wenjuan Zhou, Qin Wang, Yuanan Chen, Xiao-xing Zou, Fangyou Chen, Yingxuan Quan
{"title":"A New Lignan from Leaves of Ormosia xylocarpa","authors":"Lin Ni, Wenjuan Zhou, Qin Wang, Yuanan Chen, Xiao-xing Zou, Fangyou Chen, Yingxuan Quan","doi":"10.25135/rnp.338.2203.2386","DOIUrl":"https://doi.org/10.25135/rnp.338.2203.2386","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47710499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Silico Study of Natural Xanthones as Potential Inhibitors of Alpha-Glucosidase and Alpha-Amylase 天然山酮作为α -葡萄糖苷酶和α -淀粉酶潜在抑制剂的硅片研究
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-06-21 DOI: 10.25135/rnp.337.2203.2391
M. Jauhar, I. Anshori, Michaella Yosephine, Putri Hawa Syaifie, Azza Hanif Harisna, D. W. Nugroho, E. Mardliyati, Adzani Gaisani Arda
{"title":"In Silico Study of Natural Xanthones as Potential Inhibitors of Alpha-Glucosidase and Alpha-Amylase","authors":"M. Jauhar, I. Anshori, Michaella Yosephine, Putri Hawa Syaifie, Azza Hanif Harisna, D. W. Nugroho, E. Mardliyati, Adzani Gaisani Arda","doi":"10.25135/rnp.337.2203.2391","DOIUrl":"https://doi.org/10.25135/rnp.337.2203.2391","url":null,"abstract":": Type 2 diabetes mellitus is a disease caused by insulin resistance. Many types of oral medications exist, but the effectiveness and side effects differ from patient to patient, so alternative drugs are still required. One compound group receiving much scientific interest regarding its antidiabetic potential is xanthones as potential alpha-glucosidase and alpha-amylase inhibitors. This study performed molecular docking simulations on all 515 natural xanthones with alpha-glucosidase and alpha-amylase as the protein targets. We found 31 unique ligands that comply, and the three best ligands per protein target were filtered based on how many active site residues the ligands interacted with the targets. The three best alpha-glucosidase inhibitors are 3,4,5,8-tetrahydroxy-1,2-diisoprenylxanthone, Polygalaxanthone V, and Polygalaxanthone VII. As for alpha-amylase, we found 1-O-primeverosyl-3,8-dihydroxy-5-methoxyxanthone, Garcimangosone C, and Mangostinone as the best inhibitors. The six chosen and standard ligands underwent 2 ns molecular dynamics simulations. Both standard ligands had the highest interaction energies, followed by complexes with glycosylated xanthones, and prenylated xanthones. We also found that the prenylated xanthones could retain their initial protein-ligand interactions. Therefore, this is the first study that revealed prenylated xanthones have a good potential as anti-type 2 diabetes mellitus agents among other xanthones groups through in silico method.","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41522469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psammosilenin C, a New Cyclic Peptide from Psammosilene tunicoides Psammsilenin C，一种来自Psammselene tumoides的新环状肽
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-06-21 DOI: 10.25135/rnp.336.2203.2399
Yanhong Li, Xiu-xia Yang, X. Bai, Hongrui Li, Jingxian Sun, Yong Xiong, Xiangzhong Huang
{"title":"Psammosilenin C, a New Cyclic Peptide from Psammosilene tunicoides","authors":"Yanhong Li, Xiu-xia Yang, X. Bai, Hongrui Li, Jingxian Sun, Yong Xiong, Xiangzhong Huang","doi":"10.25135/rnp.336.2203.2399","DOIUrl":"https://doi.org/10.25135/rnp.336.2203.2399","url":null,"abstract":"04, 2022) Abstract: Phytochemical investigation of Psammosilene tunicoides led to isolation of a new cyclicpeptide, psammosilenin C ( 1 ) and three known compounds, 1-O-( β -D-glucopyranosyl)-(2 S ,3 R ,4 E ,8 E )-2-[(2 R )-2-hydroxypentadecanoylamino]-4,8-octadecadiene-1,3-diol ( 2 ), dihydroferulic acid ( 3 ) and vanillylacetone ( 4 ). Their structures were elucidated by comprehensive spectroscopic methods, including 1D and 2D NMR spectroscopic, and HR-ESI-MS spectrometric data. Compounds 1 , 2 and 4 showed inhibitory activities on lipopolysaccharide (LPS)-induced NO release in RAW","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42000811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Megastigmane Glycoside and Other Constituents from Amomum muricarpum Elmer 一种新发现的木砂草苷及其它成分
IF 1.9 4区 生物学
Records of Natural Products Pub Date : 2022-06-06 DOI: 10.25135/rnp.333.2203.2395
Do Hoang Giang, T. Phuong, N. Dang, Nguyen Thi Hong Anh, Dat Nguyen Tien
{"title":"A New Megastigmane Glycoside and Other Constituents from Amomum muricarpum Elmer","authors":"Do Hoang Giang, T. Phuong, N. Dang, Nguyen Thi Hong Anh, Dat Nguyen Tien","doi":"10.25135/rnp.333.2203.2395","DOIUrl":"https://doi.org/10.25135/rnp.333.2203.2395","url":null,"abstract":"","PeriodicalId":21053,"journal":{"name":"Records of Natural Products","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46532166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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