没药烯烯C，一种新的没药根倍半萜类化合物

IF 1.5 4区生物学 Q3 CHEMISTRY, APPLIED

Records of Natural Products Pub Date : 2022-07-25 DOI:10.25135/rnp.343.2203.2396

T. Duong, Hoang-Dung Nguyen, H. T. Nguyen, T. Nguyen, Ngoc‐Hong Nguyen, Huu-Hung Nguyen, J. Sichaem

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引用次数: 0

摘要

：对生长在越南的紫檀根的植物化学研究提供了一种新的真结烷倍半萜，紫檀烯C（1），以及七种已知的化合物，rel-5-（3S，8S-二羟基-1R，5S-二甲基-7-氧杂-6-氧双环[3,2,1]-辛-8-基）-3-甲基-2Z，4E-戊二烯酸（2），1-O-（4-羟基-2,6-二甲氧基苯氧基）-6-O-[rel-5-（3S，8S-二羟基-1R，5S-二甲基-7-氧代-6-氧代双环[3,2,1]-辛-8-基）-3-甲基-2Z，4E-戊二烯酰基]-β-D-吡喃葡萄糖（3）、姜黄素（4）、去甲氧基姜黄素（5）、双去甲氧基姜黄素（6）、（1E，6E）-1,7-双（4-甲氧基苯基）-1,6-庚二烯-3,5-二酮（7）和桑乔内酯（8）。通过分析它们的MS和NMR数据以及通过与文献值的比较来确定结构。评估所有化合物对抗生素耐药性致病菌粪肠球菌、金黄色葡萄球菌和鲍曼不动杆菌的抗菌活性。出版物。保留所有权利。

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Myrrhalindenane C, a New Eudesmane Sesquiterpenoid From Lindera Myrrha Roots

: Phytochemical investigation of Lindera myrrha roots growing in Vietnam afforded a new eudesmane sesquiterpenoid, myrrhalindenane C ( 1 ), along with seven known compounds, rel -5-(3 S ,8 S -dihydroxy-1 R ,5 S -dimethyl-7-oxa-6-oxobicyclo[3,2,1]-oct-8-yl)-3-methyl-2 Z ,4 E -pentadienoic acid ( 2 ), 1- O -(4-hydroxy-2,6-dimethoxyphenoxy)-6- O -[ rel -5-(3 S ,8 S -dihydroxy-1 R ,5 S -dimethyl-7-oxa-6-oxobicyclo[3,2,1]-oct-8-yl)-3-methyl-2 Z ,4 E -pentadienoyl]-β-D-glucopyranose ( 3 ), curcumin ( 4 ), demethoxycurcumin ( 5 ), bisdemethoxycurcumin ( 6 ), (1 E ,6 E )-1,7-bis(4-methoxyphenyl)-1,6-heptadiene-3,5-dione ( 7 ), and sanjoseolide ( 8 ). The structures were determined by analysis of their MS and NMR data as well as by comparison with literature values. All compounds were evaluated for antimicrobial activity against antibiotic-resistant, pathogenic bacteria Enterococcus faecium, Staphylococcus aureus , and Acinetobacter baumannii . Publications. All rights reserved.

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来源期刊

Records of Natural Products 生物-医药化学

CiteScore

3.10

自引率

26.30%

发文量

审稿时长

4 months

期刊介绍： Records of Natural Products is a journal of natural product chemistry. Reviews, book reviews, research papers and short reports are considered on the substances of plants, microbes and animals. Discussions on the structure elucidation, synthesis of naturally occurring compounds and biological activity of natural compounds and plant extracts, biosynthesis of natural products and essential oils of aromatic plants as well as chemotaxonomy in the field of plants are welcomed in the journal. All published research articles in Records of Natural Products have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by expert referees.