Psammsilenin C，一种来自Psammselene tumoides的新环状肽

IF 1.5 4区生物学 Q3 CHEMISTRY, APPLIED

Records of Natural Products Pub Date : 2022-06-21 DOI:10.25135/rnp.336.2203.2399

Yanhong Li, Xiu-xia Yang, X. Bai, Hongrui Li, Jingxian Sun, Yong Xiong, Xiangzhong Huang

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引用次数: 0

摘要

2022年4月4日）摘要：对盾叶沙麦的植物化学研究分离出一种新的环肽——盾叶沙梅素C（1）和三种已知化合物，1-O-（β-D-吡喃葡萄糖基）-（2S，3R，4E，8E）-2-[（2R）-2-羟基十五烷酰基氨基]-4,8-十八碳二烯-1,3-二醇（2）、二氢阿魏酸（3）和香草内酯（4）。通过综合光谱方法，包括1D和2D NMR光谱以及HR-ESI-MS光谱数据，阐明了它们的结构。化合物1、2和4对脂多糖（LPS）诱导的RAW中NO释放具有抑制活性

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Psammosilenin C, a New Cyclic Peptide from Psammosilene tunicoides

04, 2022) Abstract: Phytochemical investigation of Psammosilene tunicoides led to isolation of a new cyclicpeptide, psammosilenin C ( 1 ) and three known compounds, 1-O-( β -D-glucopyranosyl)-(2 S ,3 R ,4 E ,8 E )-2-[(2 R )-2-hydroxypentadecanoylamino]-4,8-octadecadiene-1,3-diol ( 2 ), dihydroferulic acid ( 3 ) and vanillylacetone ( 4 ). Their structures were elucidated by comprehensive spectroscopic methods, including 1D and 2D NMR spectroscopic, and HR-ESI-MS spectrometric data. Compounds 1 , 2 and 4 showed inhibitory activities on lipopolysaccharide (LPS)-induced NO release in RAW

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来源期刊

Records of Natural Products 生物-医药化学

CiteScore

3.10

自引率

26.30%

发文量

审稿时长

4 months

期刊介绍： Records of Natural Products is a journal of natural product chemistry. Reviews, book reviews, research papers and short reports are considered on the substances of plants, microbes and animals. Discussions on the structure elucidation, synthesis of naturally occurring compounds and biological activity of natural compounds and plant extracts, biosynthesis of natural products and essential oils of aromatic plants as well as chemotaxonomy in the field of plants are welcomed in the journal. All published research articles in Records of Natural Products have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by expert referees.