Respiratory Physiology & Neurobiology最新文献_第10页

Low level CO2 supplementation maintains isocapnia and reveals ventilatory long-term facilitation in rats 低水平的二氧化碳补充维持异氧血症，揭示大鼠的通气长期促进作用

IF 2.3 4区医学

Respiratory Physiology & Neurobiology Pub Date : 2023-11-05 DOI: 10.1016/j.resp.2023.104185

Shawn Miller Jr , Edgar Juarez Lopez , Jessica M.L. Grittner , Brendan J. Dougherty

{"title":"Low level CO2 supplementation maintains isocapnia and reveals ventilatory long-term facilitation in rats","authors":"Shawn Miller Jr , Edgar Juarez Lopez , Jessica M.L. Grittner , Brendan J. Dougherty","doi":"10.1016/j.resp.2023.104185","DOIUrl":"https://doi.org/10.1016/j.resp.2023.104185","url":null,"abstract":"<div><p>Acute, intermittent hypoxia (AIH) induces ventilatory long-term facilitation (vLTF) in awake, freely behaving rats under poikilocapnic and isocapnic experimental conditions. Establishing pre-clinical methods for vLTF induction that more closely align with successful protocols in humans and anesthetized rats would minimize dissonance in experimental findings and improve translational aspects of vLTF. Here, we tested several levels of low-dose CO<sub>2</sub> supplementation during and after AIH to determine 1) the lowest amount of inspired CO<sub>2</sub> that would maintain isocapnia in rats during a vLTF protocol, and 2) the net impact of supplemental CO<sub>2</sub> on vLTF expression. Rats received one of four levels of inspired CO<sub>2</sub> (0%, 0.5%, 1% or 2%) administered during AIH and for the 60 min following AIH to quantify vLTF. Our findings indicated that 2% inspired CO<sub>2</sub> was sufficient to maintain isocapnia across the AIH protocol and reveal significant vLTF. These findings provide evidence-based support for using 2% supplemental CO<sub>2</sub> during and after AIH when assessing vLTF in rats.</p></div>","PeriodicalId":20961,"journal":{"name":"Respiratory Physiology & Neurobiology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1569904823001738/pdfft?md5=0f56e4a33e227a009bb3e20619e4e658&pid=1-s2.0-S1569904823001738-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92053964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Closed-loop cervical epidural stimulation partially restores ipsilesional diaphragm EMG after acute C2 hemisection 急性C2半切后，闭路硬膜外刺激可部分恢复同侧膈肌肌电图

IF 2.3 4区医学

Respiratory Physiology & Neurobiology Pub Date : 2023-11-01 DOI: 10.1016/j.resp.2023.104182

Alyssa R. Mickle , Jesús D. Peñaloza-Aponte , Richard Coffey , Natale A. Hall , David Baekey , Erica A. Dale

{"title":"Closed-loop cervical epidural stimulation partially restores ipsilesional diaphragm EMG after acute C2 hemisection","authors":"Alyssa R. Mickle , Jesús D. Peñaloza-Aponte , Richard Coffey , Natale A. Hall , David Baekey , Erica A. Dale","doi":"10.1016/j.resp.2023.104182","DOIUrl":"https://doi.org/10.1016/j.resp.2023.104182","url":null,"abstract":"<div><p>Cervical spinal cord injury creates lasting respiratory deficits which can require mechanical ventilation long-term. We have shown that closed-loop epidural stimulation (CL-ES) elicits respiratory plasticity in the form of increased phrenic network excitability (Malone et. al., E Neuro, Vol 9, 0426–21.2021, 2022); however, the ability of this treatment to create functional benefits for breathing function per se after injury has not been demonstrated. Here, we demonstrate in C2 hemisected anesthetized rats, a 20-minute bout of CL-ES administered at current amplitudes below the motor threshold restores paralyzed hemidiaphragm activity in-phase with breathing while potentiating contralesional activity. While this acute bout of stimulation did not elicit the increased network excitability seen in our chronic model, a subset of stimulated animals continued spontaneous ipsilesional diaphragm activity for several seconds after stopping stimulation. These results support the use of CL-ES as a therapeutic to rescue breathing after high cervical spinal cord injury, with the potential to lead to lasting recovery and device independence.</p></div>","PeriodicalId":20961,"journal":{"name":"Respiratory Physiology & Neurobiology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92053963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of body postures on respiratory muscle force and coughing in healthy people 身体姿势对健康人呼吸肌肉力量和咳嗽的影响。

IF 2.3 4区医学

Respiratory Physiology & Neurobiology Pub Date : 2023-10-21 DOI: 10.1016/j.resp.2023.104181

Rui Yu , Tatsuma Okazaki , Yuzhuo Ren , Junko Okuyama , Satoru Ebihara , Shin-Ichi Izumi

{"title":"Effects of body postures on respiratory muscle force and coughing in healthy people","authors":"Rui Yu , Tatsuma Okazaki , Yuzhuo Ren , Junko Okuyama , Satoru Ebihara , Shin-Ichi Izumi","doi":"10.1016/j.resp.2023.104181","DOIUrl":"10.1016/j.resp.2023.104181","url":null,"abstract":"<div><p>The respiratory muscle<span><span> force determines the intensity of cough force. A greater cough force for cleaning the airways is essential for preventing and managing pneumonia. Body posture can affect the onset of aspiration pneumonia<span>. However, the effects of body posture on the respiratory muscle and cough forces remain unclear. Thus, we aimed to explore the influence of the four body postures on respiratory muscle force, cough pressure, subjective ease of coughing, and pulmonary function<span> in healthy individuals. Twenty healthy individuals were included in this study. Body postures were 0-degree supine, 30- and 60-degree semi-recumbent, and 90-degree sitting. The maximal inspiratory and expiratory pressures, maximal cough pressure, subjective ease of coughing, and pulmonary function, including peak expiratory flow, were evaluated. We set the measured values in the supine posture to 100% and showed the relative values. The 60-degree posture showed stronger inspiratory (125.1 ± 3.9%, mean ± standard error [SE]) and expiratory (116.4 ± 3.0%) muscle force, cough pressure, more subjective ease of coughing, and greater peak expiratory flow (113.4 ± 3.0%) than the supine posture. The sitting posture also showed greater inspiratory muscle force and peak expiratory flow than the supine posture. The correlation coefficient for the 60-degree posture showed that the </span></span></span>maximal inspiratory pressure was moderately correlated with the maximal expiratory pressure (r = 0.512), cough pressure (r = 0.495), and peak expiratory flow (r = 0.558). The above findings suggest the advantage of keeping a 60-degree posture and avoiding the supine posture to generate a greater cough force in the prevention and management of pneumonia.</span></p></div>","PeriodicalId":20961,"journal":{"name":"Respiratory Physiology & Neurobiology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49692202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sarcopenia of the longitudinal tongue muscles in rats 大鼠舌纵肌的肌肉萎缩。

IF 2.3 4区医学

Respiratory Physiology & Neurobiology Pub Date : 2023-10-18 DOI: 10.1016/j.resp.2023.104180

Gary C. Sieck, Genesis A. Hernandez-Vizcarrondo, Alyssa D. Brown, Matthew J. Fogarty

{"title":"Sarcopenia of the longitudinal tongue muscles in rats","authors":"Gary C. Sieck, Genesis A. Hernandez-Vizcarrondo, Alyssa D. Brown, Matthew J. Fogarty","doi":"10.1016/j.resp.2023.104180","DOIUrl":"10.1016/j.resp.2023.104180","url":null,"abstract":"<div><p>The tongue is a muscular hydrostat, with lingual movements occurring during breathing, chewing, swallowing, vocalization, vomiting, coughing and grooming/sexual activities. In the elderly, reduced lingual dysfunction and weakness contribute to increased risks of obstructive sleep apnea and aspiration pneumonia. In Fischer 344 (F344) rats, a validated model of aging, hypoglossal motor neuron death is apparent, although there is no information regarding tongue strength. The intrinsic tongue muscles, the superior and inferior longitudinal, transversalis and verticalis exist in an interdigitated state. Recently, we established a method to measure the specific force of individual intrinsic tongue muscle, accounting for the tissue bulk that is not in the direction of uniaxial force. In the longitudinal muscles of 6- (<em>n</em> = 10), 18- (<em>n</em> = 9) and 24-month-old (<em>n</em> = 12) female and male F344 rats, we assessed specific force, fatigability, fiber type dependent cross-sectional area (CSA) and overall CSA. Muscle force and fatigue was assessed <em>ex vivo</em> using platinum plate simulation electrodes. Tongue muscles were frozen in melting isopentane, and transverse sections cut at 10 µm. Muscle fiber type was classified based on immunoreactivity to myosin heavy chain (MyHC) isoform antibodies. In H&E stained muscle, CSA and uniaxial muscle contributions to total tongue bulk was assessed. We observed a robust ∼30% loss of longitudinal specific force, with reductions in overall longitudinal muscle fiber CSA and specific atrophy of type IIx/IIb fibers. It will be important to investigate the mechanistic underpinnings of hypoglossal motor neuron death and tongue muscle weakness to eventually provide therapies for age-associated lingual dysfunctions.</p></div>","PeriodicalId":20961,"journal":{"name":"Respiratory Physiology & Neurobiology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49681721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cough and swallow after laparotomy in anesthetized cats 麻醉猫剖腹手术后咳嗽和吞咽。

IF 2.3 4区医学

Respiratory Physiology & Neurobiology Pub Date : 2023-10-17 DOI: 10.1016/j.resp.2023.104179

Ivan Poliacek , Lukas Martvon , Michal Simera , Marcel Veternik , Jakub Misek , Lucia Cibulkova , Kimberly E. Iceman , Donald C. Bolser , Teresa Pitts

{"title":"Cough and swallow after laparotomy in anesthetized cats","authors":"Ivan Poliacek , Lukas Martvon , Michal Simera , Marcel Veternik , Jakub Misek , Lucia Cibulkova , Kimberly E. Iceman , Donald C. Bolser , Teresa Pitts","doi":"10.1016/j.resp.2023.104179","DOIUrl":"10.1016/j.resp.2023.104179","url":null,"abstract":"<div><p><span>An anesthetized cat animal model was used to evaluate changes in cough and swallow after a small midline upper abdominal </span>incision<span><span><span> (laparotomy). Two additional conditions were tested: sealing the laparotomy<span> with gentle suctioning via a small cannula<span>, and subsequent closure of the abdominal wall with suture. These abdominal wall manipulations resulted in no changes in the </span></span></span>cough reflex, but produced higher motor drive to pharyngeal musculature (thyropharyngeus and geniohyoid muscles) during swallow. Swallow-breathing coordination phase preference shifted towards swallow occurring more during the inspiratory phase. There were no significant changes in cough motor pattern, or cough and swallow number and temporal features. The respiratory changes were limited to reduced inspiratory motor drive to the diaphragm. The results are consistent with an important role of </span>sensory feedback from the abdominal wall in regulation of swallow motor pattern. The level of reflex modulation may depend on the extent of injury and likely on its position in the abdomen.</span></p></div>","PeriodicalId":20961,"journal":{"name":"Respiratory Physiology & Neurobiology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49681720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of high-intensity interval hyperpnea on aerobic energy release and inspiratory muscle fatigue 高强度间歇性高通气对有氧能量释放和吸气肌疲劳的影响。

IF 2.3 4区医学

Respiratory Physiology & Neurobiology Pub Date : 2023-10-13 DOI: 10.1016/j.resp.2023.104170

Suzuna Sato , Koji Ishida , Noriko I. Tanaka , Keisho Katayama

{"title":"Impact of high-intensity interval hyperpnea on aerobic energy release and inspiratory muscle fatigue","authors":"Suzuna Sato , Koji Ishida , Noriko I. Tanaka , Keisho Katayama","doi":"10.1016/j.resp.2023.104170","DOIUrl":"10.1016/j.resp.2023.104170","url":null,"abstract":"<div><p>Respiratory muscle endurance training reportedly has beneficial effects on whole-body endurance performance. We produced a novel high-intensity interval (HII) protocol and characterized the associated physiological responses and respiratory muscle fatigue. Peak oxygen uptake of respiratory muscle (V̇O2peakRM) was estimated during the respiratory incremental test. The HII session consisted of five 3-minute hyperpnea periods at 100%V̇O2peakRM interspersed with 2-minute periods at 40%V̇O2peakRM (25 min total). The high-intensity continuous (HIC) session involved a single time-to-end bout of hyperpnea at 100%V̇O2peakRM. The moderate-intensity continuous (MIC) session involved 25 min of hyperpnea at 60% of maximal voluntary ventilation. V̇O2RM was recorded continuously, and maximal inspiratory pressure (PImax) was assessed before and after the sessions. HII session: V̇O2RM gradually increased as the sets proceeded, whereas PImax decreased significantly. HIC session: V̇O2RM increased progressively, and the time to end was 6.5 ± 0.5 min. PImax decreased significantly. MIC session: V̇O2RM did not change for 25 min, and PImax remained unchanged. The duration of V̇O2RM at near- and supra-maximal levels in the HII session (10 ± 1 min) was longer than that in the HIC session (4 ± 1 min). The decrease in PImax was larger in the HII session (−12 ± 3 %) than MIC session (−4 ± 3 %). The HII protocol is characterized by a longer time to maximally stimulate the aerobic energy system of respiratory muscle than the HIC protocol and greater inspiratory muscle fatigue than the traditional MIC protocol. These results suggest that the HII protocol could enhance the efficacy of respiratory muscle training programs.</p></div>","PeriodicalId":20961,"journal":{"name":"Respiratory Physiology & Neurobiology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41210915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary oxygen toxicity index during linear change in PO2: HBO treatment tables and dive planning PO2线性变化期间的肺氧毒性指数:高压氧治疗表和潜水计划

IF 2.3 4区医学

Respiratory Physiology & Neurobiology Pub Date : 2023-10-12 DOI: 10.1016/j.resp.2023.104172

R. Arieli

引用次数: 0

Muscle oxygen supply impairment during maximal exercise in patients undergoing dialysis therapy 接受透析治疗的患者在最大运动量期间肌肉氧供应受损。

IF 2.3 4区医学

Respiratory Physiology & Neurobiology Pub Date : 2023-10-09 DOI: 10.1016/j.resp.2023.104169

Amal Machfer , Sémah Tagougui , Nadia Fekih , Hayfa Ben Haj Hassen , Hassen Ibn Hadj Amor , Mohamed Amine Bouzid , Hamdi Chtourou

{"title":"Muscle oxygen supply impairment during maximal exercise in patients undergoing dialysis therapy","authors":"Amal Machfer , Sémah Tagougui , Nadia Fekih , Hayfa Ben Haj Hassen , Hassen Ibn Hadj Amor , Mohamed Amine Bouzid , Hamdi Chtourou","doi":"10.1016/j.resp.2023.104169","DOIUrl":"10.1016/j.resp.2023.104169","url":null,"abstract":"<div><p>This study aimed to investigate whether Chronic Kidney Disease (CKD) influences O<sub>2</sub> supply including O<sub>2</sub> delivery and release to the active muscles during maximal physical exercise. Twelve CKD patients undergoing dialysis therapy (HD group) and twelve healthy adults (CTR group) performed an incremental exercise test to determine maximal oxygen uptake (VO<sub>2peak</sub>). Throughout the exercise, near-infrared spectroscopy allowed the investigation of changes in oxyhemoglobin (∆O<sub>2</sub>Hb), deoxyhemoglobin (∆HHb), and total hemoglobin (∆THb) in the vastus lateralis muscle. VO<sub>2peak</sub> was significantly lower in HD group. In addition, HD patients had impaired changes in muscular oxygenation (∆HHb and ∆O<sub>2</sub>Hb) and blood volume (∆THb) during the exercise (p < 0.05). Moreover, a positive correlation was observed between VO<sub>2peak</sub> and muscle blood volume (∆THb) in both groups (p < 0.05). This study provides the first evidence that HD patients displayed lower VO<sub>2peak</sub> and blunted muscular deoxyhemoglobin increase during exercise. This result supports the hypothesis of an increase in oxygen affinity and/or mitochondrial dysfunction in this population.</p></div>","PeriodicalId":20961,"journal":{"name":"Respiratory Physiology & Neurobiology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41183408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights into exercise-induced rhinitis based on nasal aerodynamics induced by airway morphology 基于气道形态学诱导的鼻腔空气动力学对运动性鼻炎的见解。

IF 2.3 4区医学

Respiratory Physiology & Neurobiology Pub Date : 2023-10-07 DOI: 10.1016/j.resp.2023.104171

Sarah M. Russel , Raluca E. Gosman , Katherine Gonzalez , Joshua Wright , Dennis O. Frank-Ito

{"title":"Insights into exercise-induced rhinitis based on nasal aerodynamics induced by airway morphology","authors":"Sarah M. Russel , Raluca E. Gosman , Katherine Gonzalez , Joshua Wright , Dennis O. Frank-Ito","doi":"10.1016/j.resp.2023.104171","DOIUrl":"10.1016/j.resp.2023.104171","url":null,"abstract":"<div><h3>Background</h3><p>Exercise-induced rhinitis (EIR) is a poorly understood phenomenon that may be related to increased inspiratory airflow. Characterization of the development of EIR is important to understand contributing factors.</p></div><div><h3>Objective</h3><p>To characterize how different nasal morphologies respond to airflow-related variables during rapid/deep inspiratory conditions.</p></div><div><h3>Methods</h3><p>Subject-specific nasal airways were reconstructed from radiographic images. Unilateral airways were classified as Standard, Notched, or Elongated accord to their distinct nasal vestibule morphology. Computational fluid dynamics simulations were performed at various airflow rates.</p></div><div><h3>Results</h3><p>For all simulated flow rates, average resistance at the nasal vestibule, airflow velocity and wall sheer stress were highest in Notched. Average mucosal heat flux was highest in Standard. Notched phenotypes showed lower mean percent increases from 10 L/min to 50 L/min in all computed variables.</p></div><div><h3>Conclusion</h3><p>Resistance values and airflow velocities depicted a more constricted nasal vestibule in the Notched phenotypes, while perception of nasal mucosal cooling (heat flux) favored the Standard phenotypes. Different nasal phenotypes may predispose to EIR.</p></div>","PeriodicalId":20961,"journal":{"name":"Respiratory Physiology & Neurobiology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41183407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physiological responses during static apnoea efforts in elite and novice breath-hold divers before and after two weeks of dry apnoea training 精英和新手屏息潜水员在两周的干呼吸暂停训练前后进行静态呼吸暂停训练时的生理反应。

IF 2.3 4区医学

Respiratory Physiology & Neurobiology Pub Date : 2023-10-04 DOI: 10.1016/j.resp.2023.104168

Dimitrios I. Bourdas , Nickos D. Geladas

{"title":"Physiological responses during static apnoea efforts in elite and novice breath-hold divers before and after two weeks of dry apnoea training","authors":"Dimitrios I. Bourdas , Nickos D. Geladas","doi":"10.1016/j.resp.2023.104168","DOIUrl":"10.1016/j.resp.2023.104168","url":null,"abstract":"<div><p>This study examined the effect of breath-hold (BH) training on apnoeic performance in novice BH divers (NBH:n = 10) and compared them with data from elite BH divers (EBH:n = 11). Both groups performed 5-maximal BHs (PRE). The NBH group repeated this protocol after two weeks of BH training (POST). The NBH group during BH efforts significantly increased red blood cell concentration (4.56 ± 0.16Mio/μl) by 5.06%, hemoglobin oxygen saturation steady state duration (110.32 ± 29.84 s) by 15.48%, and breath-hold time (BHT:144.19 ± 47.35 s) by 33.77%, primarily due to a 59.70% increase in struggle phase (71.85 ± 30.89 s), in POST. EBH group exhibited longer BHT (283.95 ± 36.93 s) and struggle-phase (150.10 ± 34.69 s) than NBH (POST). Elite divers recorded a higher peak MAP (153.18 ± 12.28 mmHg) compared to novices (PRE:123.70 ± 15.65 mmHg, POST:128.30 ± 19.16 mmHg), suggesting that a higher peak MAP is associated with a better BHT. The concurrent abrupt increase of diaphragmatic activity and MAP, seen only in the EBH group, suggests a potential interaction. Additionally, apnoea training increases red blood cells concentration in repeated apnoea efforts and increases BH stamina.</p></div>","PeriodicalId":20961,"journal":{"name":"Respiratory Physiology & Neurobiology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41102337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0