Regenerative Biomaterials最新文献_第4页

Correction to: Degradation behavior of porous magnesium alloy scaffold under the low-intensity pulsed ultrasound intervention and their effect on bone defects repair. 修正：低强度脉冲超声介入下多孔镁合金支架的降解行为及其对骨缺损修复的影响。

IF 5.6 1区医学

Regenerative Biomaterials Pub Date : 2025-06-17 eCollection Date: 2025-01-01 DOI: 10.1093/rb/rbaf055

引用次数: 0

Matrix stiffness boosts PDAC chemoresistance via SCD1-dependent lipid metabolic reprogramming. 基质硬度通过scd1依赖性脂质代谢重编程增强PDAC化疗耐药。

IF 8.1 1区医学

Regenerative Biomaterials Pub Date : 2025-06-16 eCollection Date: 2025-01-01 DOI: 10.1093/rb/rbaf056

Xue Zhang, Biwen Zhu, Jiashuai Yan, Xi Chen, Di Wu, Zhen Wang, Xiaoqi Guan, Yan Huang, Yahong Zhao, Yumin Yang, Yibing Guo

{"title":"Matrix stiffness boosts PDAC chemoresistance via SCD1-dependent lipid metabolic reprogramming.","authors":"Xue Zhang, Biwen Zhu, Jiashuai Yan, Xi Chen, Di Wu, Zhen Wang, Xiaoqi Guan, Yan Huang, Yahong Zhao, Yumin Yang, Yibing Guo","doi":"10.1093/rb/rbaf056","DOIUrl":"10.1093/rb/rbaf056","url":null,"abstract":"PDAC cells perceive and respond to mechanical stimuli in their extracellular microenvironments (ECMs), playing a crucial role in chemoresistance, while the underlying mechanisms are not fully understood. The progression of various solid tumors is accompanied by metabolic reprogramming. RNA-seq and untargeted metabolomics analysis indicated that stiff substrate may regulate lipid metabolism. The expression of lipogenesis-related genes, including fatty acid synthase (FASN), ATP citrate lyase (ACLY) and acetyl-CoA carboxylase (ACC) was elevated, also the sum of lipid droplets and the triglyceride content. Herein, whether lipid metabolism is involved in matrix stiffness-mediated PDAC chemoresistance and the in-depth mechanism were further explored. Rescue with C75 (FASN inhibitor) validated that fatty acid synthesis participated in matrix stiffness-regulated chemoresistance. Simultaneously, the SCD1 expression was reinforced, consistent with PDAC tissues. The concurrent restraint SCD1 (with inhibitor CAY10566 or shSCD1) and addition of oleic acid confirmed that SCD1 is involved in matrix stiffness-mediated chemoresistance through fatty acid synthesis. In addition, Piezo1 regulated SCD1 expression through the augmentation of Ca2+ influx, and the PI3K/Akt pathway participated in this process. Taken together, our research sheds light on lipid metabolism exerts an essential role during matrix stiffness-mediated chemoresistance through Piezo1-elicited elevation of SCD1. Our findings delivered a supplement PDAC chemoresistance mechanism mediated by matrix stiffness from the perspective of lipid metabolic reprogramming, and provided a novel strategy for improving clinical therapies.","PeriodicalId":20929,"journal":{"name":"Regenerative Biomaterials","volume":"12 ","pages":"rbaf056"},"PeriodicalIF":8.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12308179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineering of tissue in microphysiological systems demonstrated by modelling skeletal muscle. 骨骼肌模型证明了微生理系统中的组织工程。

IF 8.1 1区医学

Regenerative Biomaterials Pub Date : 2025-06-16 eCollection Date: 2025-01-01 DOI: 10.1093/rb/rbaf059

Yuan Gao, Zilin Zhang, Yu Yao, Jing Zhang, Xiaoran Li, Keyu Yang, Nuo Si, Zaozao Chen, Zhongze Gu, Ningbei Yin

{"title":"Engineering of tissue in microphysiological systems demonstrated by modelling skeletal muscle.","authors":"Yuan Gao, Zilin Zhang, Yu Yao, Jing Zhang, Xiaoran Li, Keyu Yang, Nuo Si, Zaozao Chen, Zhongze Gu, Ningbei Yin","doi":"10.1093/rb/rbaf059","DOIUrl":"10.1093/rb/rbaf059","url":null,"abstract":"Research on myogenesis and myogenic pathologies has garnered significant attention in recent years. However, traditional in vitro modeling approaches have struggled to fully replicate the complex functions of skeletal muscle. This limitation is primarily due to the insufficient reconstruction of the muscle tissue microenvironment and the role of physical cues in regulating muscle cell activity. Recent studies have highlighted the importance of the microenvironment, which includes cells, extracellular matrix (ECM) and cytokines, in influencing myogenesis, regeneration and inflammation. This review focuses on advances in skeletal muscle construction toward a complete microphysiological system, such as organoids and muscle-on-a-chip technology, as well as innovative interventions like bioprinting and electrical stimulation. These advancements have enabled researchers to restore functional skeletal muscle tissue, bringing us closer to achieving a fully functional microphysiological system. Compared to traditional models, these systems allow for the collection of more comprehensive data, providing insights across multiple scales. Researchers can now study skeletal muscle and disease models in vitro with increased precision, enabling more advanced research into the physiological and biochemical cues affecting skeletal muscle activity. With these advancements, new applications are emerging, including drug screening, disease modeling and the development of artificial tissues. Progression in this field holds great promise for advancing our understanding of skeletal muscle function and its associated pathologies, offering potential therapeutic solutions for a variety of muscle-related diseases.","PeriodicalId":20929,"journal":{"name":"Regenerative Biomaterials","volume":"12 ","pages":"rbaf059"},"PeriodicalIF":8.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12289553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fibrotic lung ECM upregulates SDC4/integrin-αvβ1 interaction and the interfering peptide SDC4_87-131 and its derivative peptides alleviate pulmonary fibrosis. 纤维化肺ECM上调SDC4/整合素-αvβ1相互作用，干扰肽SDC487-131及其衍生肽缓解肺纤维化。

IF 8.1 1区医学

Regenerative Biomaterials Pub Date : 2025-06-16 eCollection Date: 2025-01-01 DOI: 10.1093/rb/rbaf057

Lihua Zhu, Lingfeng Xie, Yupeng Zhi, Yihao Huang, Hongkui Chen, Zibin Chen, Jinsheng Hong, Yansong Guo, Chun Chen

{"title":"Fibrotic lung ECM upregulates SDC4/integrin-αvβ1 interaction and the interfering peptide SDC487-131 and its derivative peptides alleviate pulmonary fibrosis.","authors":"Lihua Zhu, Lingfeng Xie, Yupeng Zhi, Yihao Huang, Hongkui Chen, Zibin Chen, Jinsheng Hong, Yansong Guo, Chun Chen","doi":"10.1093/rb/rbaf057","DOIUrl":"10.1093/rb/rbaf057","url":null,"abstract":"Fibroblast activation promotes remodeling of the extracellular matrix (ECM), and the fibrotic remodeling ECM further stimulating fibroblast activation and advancing pulmonary fibrosis (PF). syndecan-4 (SDC4) is the key mediator of ECM-cell signaling, but its action in PF remains unclear. Using decellularized lung ECM (dECM), this study found that fibrotic ECM enhanced fibroblast activation via SDC4-regulated integrin-αvβ1 expression and activation, and FAK/AKT phosphorylation. Meanwhile, SDC4 knockdown inhibited fibrotic ECM-induced TGF-β1 synthesis and PKCα activation. A Duolink-proximity ligation assay confirmed extracellular interactions between SDC4 and integrin-αvβ1, and the SDC4 blocking antibody Anti-SDC4(93-121) prevented this interaction, resulting in an effect consistent with knockdown of SDC4. The interfering peptide SDC487-131 diminished the interaction between SDC4 and integrin-αvβ1, subsequently inhibited the activation of FAK/AKT, Smad2/3 and PKCα/NF-κB pathways and exhibited anti-PF activity comparable to that of SDC4 knockdown and Anti-SDC4(93-121). A docking mode of SDC487-131 with the Calf-1/Calf-2 domain of integrin-αv was constructed by using the AlphaFold2-Multimer model, and peptide design was performed to obtain a novel polypeptide chain CS-9 with enhanced anti-PF effect. This study found that the biomaterial, lung ECM, regulates fibroblast activation through the collaboration of SDC4 and integrin-αvβ1, and obtained a novel SDC487-131-derived peptide that may prevent fibrotic ECM from promoting PF.","PeriodicalId":20929,"journal":{"name":"Regenerative Biomaterials","volume":"12 ","pages":"rbaf057"},"PeriodicalIF":8.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12313019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanomaterial-assisted pancreatic cancer theranostics. 纳米材料辅助胰腺癌治疗。

IF 5.6 1区医学

Regenerative Biomaterials Pub Date : 2025-06-11 eCollection Date: 2025-01-01 DOI: 10.1093/rb/rbaf054

Yaqi Liu, Huachun Xu, Shihao Bai, Tianxiang Chen, Xuehua Ma, Jie Lin, Linglin Sun, Changyong Gao, Aiguo Wu, Qiang Li

{"title":"Nanomaterial-assisted pancreatic cancer theranostics.","authors":"Yaqi Liu, Huachun Xu, Shihao Bai, Tianxiang Chen, Xuehua Ma, Jie Lin, Linglin Sun, Changyong Gao, Aiguo Wu, Qiang Li","doi":"10.1093/rb/rbaf054","DOIUrl":"10.1093/rb/rbaf054","url":null,"abstract":"Pancreatic cancer is one of the most lethal malignancies, largely due to the limitations of current imaging technologies and treatment strategies, which hinder early diagnosis and effective disease management. Achieving precise theranostics for pancreatic cancer has become a priority, and recent advances have focused on the development of novel nanomaterials with enhanced imaging capabilities and therapeutic functionalities. These nanomaterials, through surface modifications, can significantly improve the targeting and precision of both diagnostic and therapeutic applications. Recent progress in nanomaterial design has led to the creation of multifunctional platforms that not only enhance imaging but also improve therapeutic efficacy. These innovations have spurred significant interest in the application of nanomaterials for pancreatic cancer theranostics. In this review, we highlight recent developments in the use of nanomaterials for diagnostic imaging and precision therapy in pancreatic cancer. Various applications, including magnetic, optical, acoustic and radiological imaging, as well as therapeutic strategies such as chemodynamic therapy, light-based therapy, sonodynamic therapy and gene therapy, are discussed. Despite the promising potential of these nanomaterials, several challenges remain. These include optimizing targeting mechanisms, enhancing nanomaterial stability in vivo, overcoming biological barriers and ensuring safe and effective translation to clinical settings. Addressing these challenges will require further research and innovation. With sustained efforts, nanomaterial-assisted diagnostics and therapeutics have the potential to revolutionize the management of pancreatic cancer, ultimately improving early detection and treatment outcomes. Continued progress in this field could significantly enhance the overall prognosis for pancreatic cancer patients, making it a more treatable disease in the future.","PeriodicalId":20929,"journal":{"name":"Regenerative Biomaterials","volume":"12 ","pages":"rbaf054"},"PeriodicalIF":5.6,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review of nanomaterials in osteoarthritis treatment and immune modulation. 纳米材料在骨关节炎治疗和免疫调节中的研究进展。

IF 5.6 1区医学

Regenerative Biomaterials Pub Date : 2025-06-04 eCollection Date: 2025-01-01 DOI: 10.1093/rb/rbaf048

Wei Deng, Tianshu Wang, Lei Li, Xuanyu Xiao, Yuanyuan Xu, Qiujiang Li, Qingsong Zhou, Yong Yin, Hongsheng Yang, Kai Gong, Yue Zhou, Yunbing Wang

{"title":"A review of nanomaterials in osteoarthritis treatment and immune modulation.","authors":"Wei Deng, Tianshu Wang, Lei Li, Xuanyu Xiao, Yuanyuan Xu, Qiujiang Li, Qingsong Zhou, Yong Yin, Hongsheng Yang, Kai Gong, Yue Zhou, Yunbing Wang","doi":"10.1093/rb/rbaf048","DOIUrl":"10.1093/rb/rbaf048","url":null,"abstract":"Osteoarthritis (OA) is a highly prevalent degenerative cartilage disease globally. The medical community has recognized it as one of the major public health problems today. Nanomaterials are considered the most promising avenue for OA treatment because they exhibit unique physicochemical properties such as high catalytic activity, bio-enzyme-like reaction kinetics, and modulation of joint immune responses. Besides, nanomaterials can exert higher targeting to improve therapeutic efficacy and reduce side effects. These unique advantages have led to the widespread development of nanomaterials for OA treatment, and they are gradually seeing their most prosperous moment. A timely and comprehensive review of OA pathogenesis-immunomodulation-therapeutic efficacy from a nanomaterials perspective would greatly broaden this research area. This review summarizes the recent advances in nanomaterials for OA treatment. Finally, the main challenges and opportunities for nanomaterials to modulate the immune system for OA treatment are discussed.","PeriodicalId":20929,"journal":{"name":"Regenerative Biomaterials","volume":"12 ","pages":"rbaf048"},"PeriodicalIF":5.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12187071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Curcumin-primed milk-derived extracellular vesicles remodel hair follicle microenvironment for the treatment of androgenetic alopecia. 姜黄素乳源性细胞外囊泡重塑毛囊微环境治疗雄激素性脱发。

IF 8.1 1区医学

Regenerative Biomaterials Pub Date : 2025-05-30 eCollection Date: 2025-01-01 DOI: 10.1093/rb/rbaf051

Chongchao Hou, Sihua Wang, Zihang Li, Qing Huang, Yang Jiang, Xin Zhou, Rongying Ou, Danyang Li, Yunsheng Xu

{"title":"Curcumin-primed milk-derived extracellular vesicles remodel hair follicle microenvironment for the treatment of androgenetic alopecia.","authors":"Chongchao Hou, Sihua Wang, Zihang Li, Qing Huang, Yang Jiang, Xin Zhou, Rongying Ou, Danyang Li, Yunsheng Xu","doi":"10.1093/rb/rbaf051","DOIUrl":"10.1093/rb/rbaf051","url":null,"abstract":"Androgenetic alopecia (AGA) is a globally prevalent condition, with limited treatment options and significant adverse effects associated with existing therapies. The primary pathogenic mechanisms of AGA involve androgen-mediated regulatory pathways, molecular alterations affecting hair regeneration, and inflammation in the perifollicular microenvironment. In this study, we first investigated the topical application of testosterone with varied doses for AGA mouse model induction, in which the High-dose group exhibited the most robust model development and provided a more comprehensive set of criteria for successful AGA model establishment. Then, curcumin-primed milk-derived extracellular vesicles (Cur-mEVs) were fabricated for the therapy of AGA with the in-house developed mouse model described above. It was demonstrated that Cur-mEVs remodeled the hair follicle microenvironment, evidenced by the activation of the Wnt/β-catenin signaling pathway, downregulation of transforming growth factor beta 1 expression and alleviation of perifollicular inflammation. These effects collectively regulated the hair follicle cycle and promoted hair regeneration. Overall, our results highlighted a promising therapeutic approach for AGA with potential translational possibilities.","PeriodicalId":20929,"journal":{"name":"Regenerative Biomaterials","volume":"12 ","pages":"rbaf051"},"PeriodicalIF":8.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12306444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144744486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in skeletal muscle tissue engineering: strategies for repair and regeneration of skeletal muscle beyond self-repair. 骨骼肌组织工程的进展：骨骼肌自我修复和再生的策略。

IF 5.6 1区医学

Regenerative Biomaterials Pub Date : 2025-05-28 eCollection Date: 2025-01-01 DOI: 10.1093/rb/rbaf050

Lei Qi, Fengyuan Zhang, Kexin Wang, Bingqian Chen, Xia Li, Jin Xu, Jiacheng Sun, Boya Liu, Zihui Gao, Yanan Ji, Leilei Gong, Youhua Wang, Xinlei Yao, Xiaosong Gu, Hualin Sun

{"title":"Advancements in skeletal muscle tissue engineering: strategies for repair and regeneration of skeletal muscle beyond self-repair.","authors":"Lei Qi, Fengyuan Zhang, Kexin Wang, Bingqian Chen, Xia Li, Jin Xu, Jiacheng Sun, Boya Liu, Zihui Gao, Yanan Ji, Leilei Gong, Youhua Wang, Xinlei Yao, Xiaosong Gu, Hualin Sun","doi":"10.1093/rb/rbaf050","DOIUrl":"10.1093/rb/rbaf050","url":null,"abstract":"Skeletal muscle is a vital organ of exercise and energy metabolism, playing a crucial role in maintaining body posture, enabling movement and supporting overall health. When skeletal muscle undergoes minor injuries, it has the inherent ability to self-repair and regain function. However, the ability of skeletal muscle self-repair is affected in severe muscle damage, resulting in significant muscle loss and functional impairments. For the severe muscle injury, tissue engineering strategies are used as the new methods to promote the repair and regeneration of skeletal muscle. Skeletal muscle tissue engineering (SMTE) aims to repair or regenerate skeletal muscle using seed cells, scaffolds, bioactive molecules or their combinations to reverse muscle loss caused by traumatic injury or congenital muscle defects. In this study, we provide an overview of the structure and contraction process of skeletal muscle, as well as its mechanisms of natural repair and regeneration. We describe the seed cells with myogenic potential and show natural, synthetic and composite biomaterials, as well as advanced technologies for manufacturing scaffolds used in SMTE. SMTE has broad prospects, but it still faces many challenges before clinical application. The continued advancement of muscle tissue engineering will yield innovative outcomes with significant clinical potential for skeletal muscle regeneration.","PeriodicalId":20929,"journal":{"name":"Regenerative Biomaterials","volume":"12 ","pages":"rbaf050"},"PeriodicalIF":5.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144542054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Porous PLLA microspheres dispersed in HA/collagen hydrogel as injectable facial fillers to enhance aesthetic effects. 多孔聚乳酸微球分散在透明质酸/胶原蛋白水凝胶中，作为可注射的面部填充物，增强美观效果。

IF 5.6 1区医学

Regenerative Biomaterials Pub Date : 2025-05-23 eCollection Date: 2025-01-01 DOI: 10.1093/rb/rbaf049

Miaoran Zhao, Shuhua Chang, Yunpeng Wang, Jun Cao, Yuji Pu, Bin He, Shengsheng Pan

{"title":"Porous PLLA microspheres dispersed in HA/collagen hydrogel as injectable facial fillers to enhance aesthetic effects.","authors":"Miaoran Zhao, Shuhua Chang, Yunpeng Wang, Jun Cao, Yuji Pu, Bin He, Shengsheng Pan","doi":"10.1093/rb/rbaf049","DOIUrl":"10.1093/rb/rbaf049","url":null,"abstract":"Injectable facial fillers such as Sculptra® stimulate collagen regeneration to fill wrinkles; however, the collagen regeneration is not satisfactory due to the slow emergence of filling effect. In this study, we designed a regenerative dermal filler to provide both immediate and long-lasting filling effects. A hydrogel matrix composed of crosslinked hyaluronic acid (HA) and collagen was engineered to encapsulate porous poly(L-lactide) (PLLA) microspheres and tranexamic acid (TXA). The hydrogel matrix was administered via intradermal injection to achieve wrinkle filling. TXA is released to exert skin-whitening effects, while the porous PLLA microspheres and their degradation product, lactic acid, continuously stimulate collagen regeneration over an extended period. Facial volume increased immediately following hydrogel injection. Large amounts of new Type I and Type III collagen are generated. The porous structure of PLLA microspheres facilitated the 'penetrating growth' of collagen fibers, which effectively filled facial depressions and smoothed wrinkles. Overall, the HA/collagen composite hydrogel filler exhibited excellent esthetic effects.","PeriodicalId":20929,"journal":{"name":"Regenerative Biomaterials","volume":"12 ","pages":"rbaf049"},"PeriodicalIF":5.6,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12187068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144485739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: Sulfated GAG mimetic peptide nanofibers enhance chondrogenic differentiation of mesenchymal stem cells in 3D in vitro models. 更正：硫酸酸化GAG模拟肽纳米纤维在体外3D模型中增强间充质干细胞的软骨分化。

IF 5.6 1区医学

Regenerative Biomaterials Pub Date : 2025-05-22 eCollection Date: 2025-01-01 DOI: 10.1093/rb/rbaf045

引用次数: 0