Radiation Physics and Chemistry最新文献

{"title":"Proposal for an Iodine-131-based technique derived from a Monte Carlo study for inactivating SARS-CoV-2","authors":"Jaafar EL Bakkali ,&nbsp;Tarek EL Bardouni ,&nbsp;Bouchra El Mchichi ,&nbsp;Omar Ait Sahel ,&nbsp;Khalid Ennibi ,&nbsp;Abderrahim Doudouh","doi":"10.1016/j.radphyschem.2025.112827","DOIUrl":"10.1016/j.radphyschem.2025.112827","url":null,"abstract":"<div><div>Ionizing radiation has been used for many years in the development of vaccines against viruses. Recent studies have shown that γ radiation can effectively inactivate SARS-CoV-2 at doses ≥6 kGy. In this study, we proposed a β⁻ inactivation method for SARS-CoV-2 using the Iodine-131 (I-131). Using FreeCad software, we designed five four-layered hollow spheres with varying radii. The innermost layer is a solid sphere containing 5 cc of a 30 mCi I-131. The second layer consists of a 0.2 mm thick aerographene wall that separates the I-131 from the viral sample. The third layer is designed to accommodate 1, 2, 3, 4, or 5 cc of the viral sample. The outer layer is also a aerographene wall that serves as an external surface to protect the viral samples. We estimated the S-values for the selected viral samples using InterDosi 1.4 code, with ICRP adult male blood as the material assigned to the viral samples. Knowing that the SARS-CoV-2 can be viable when refrigerated at 4 °C for 21 days, we calculated the cumulative activity of I-131 in that same period or less. The mean absorbed dose was then estimated by multiplying the S-value by the cumulative activity. Our findings reveal that a 1 cc viral sample treated with 5 cc of 30 mCi I-131 achieved the highest S-value establishing it as the most effective geometric configuration examined. Furthermore, the study indicated that a single dose of I-131 can sequentially inactivate four 1 cc viral samples over a period of a month. We concluded that beta-emitting radionuclides like I-131 could serve as effective alternatives for inactivating SARS-CoV-2.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"235 ","pages":"Article 112827"},"PeriodicalIF":2.8,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the impact of Nb2O5 on structural and shielding properties of aluminum fluorosilicate glass systems","authors":"A.M. Elsherbeny ,&nbsp;A.M. Abdelghany ,&nbsp;S.M. Ghorab ,&nbsp;R.M. Shalaby","doi":"10.1016/j.radphyschem.2025.112824","DOIUrl":"10.1016/j.radphyschem.2025.112824","url":null,"abstract":"<div><div>This study investigates the structural, optical, and gamma-ray shielding properties of aluminum fluorosilicate glasses with the composition 45SiO₂–15Al₂O₃–10CaF₂–15Na₂O–5NaF-(10-x)SrO-xNb₂O₅ (x = 0, 5, 10 mol%). Glasses were synthesized using the melt-quenching technique and characterized via XRD, FTIR, and gamma-ray attenuation measurements. XRD confirmed the amorphous nature of all samples, with Nb₂O₅ incorporation causing a shift in the broad halo position, indicating network depolymerization. FTIR analysis revealed structural modifications in Si–O–Si and Si–O–Al linkages. The introduction of Nb₂O₅ significantly enhanced gamma-ray shielding properties, with increased mass and linear attenuation coefficients, particularly at lower energies. The effective atomic number (Zeff) and equivalent atomic number (Zeq) showed a positive correlation with Nb₂O₅ content, while the energy absorption buildup factor (EABF) exhibited composition-dependent variations. These findings demonstrate that Nb₂O₅ substitution improves radiation shielding capabilities while maintaining structural stability. The study provides a foundation for developing advanced, lightweight, and transparent radiation shielding materials, offering a viable alternative to traditional heavy-metal-based shields for use in medical, nuclear, and industrial applications.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"235 ","pages":"Article 112824"},"PeriodicalIF":2.8,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynalog-based dose verification in PRIMO Monte Carlo for IMRT and VMAT head and neck cancer","authors":"Mochamad Robby Fairuzzihab Qodarul ,&nbsp;Dea Ryangga ,&nbsp;Andrian Dede Handika ,&nbsp;Supriyanto Ardjo Pawiro ,&nbsp;Akbar Azzi","doi":"10.1016/j.radphyschem.2025.112825","DOIUrl":"10.1016/j.radphyschem.2025.112825","url":null,"abstract":"<div><div>Modern linear accelerator (linac) nowadays writes the treatment delivery log within its system. This log can be reconstructed into treatment plan format as an input for the independent dose calculation (IDC) to evaluate the planned dose distribution. PRIMO, one of the Monte Carlo simulation user codes, can perform IDC using both plan parameter and treatment log history. This study aims to verify the planned dose to reconstructed log dose distribution and evaluates the use of treatment Dynalog for IDC at PRIMO program. A total of 5 planning and Dynalog files for 7-field IMRT and 2-arc VMAT head and neck cancer cases were simulated in PRIMO and compared to treatment plan dose distribution. The evaluation metrics were gamma pass rate (GPR) and percentage of agreement (PA) for delineated structure, and root-mean-square error (RMS) of multi-leaf collimators (MLC). The GPR evaluation with criteria of 3 %/3 mm, 3 %/2 mm and 2 %/2 mm were within the tolerance level of 95 %. On the other hand, PA results showed less than 99 % for almost all structures. The average of IMRT RMS was 0.020 and VMAT was 0.022. These results were below the tolerance level of 3.5 mm of dynamic MLC. The dose verification method using GPRs and RMS was relevant because the evaluation results produced within the recommendations, stricter limits of GPR 2 %/2 mm <span><math><mrow><mo>≥</mo></mrow></math></span> 95 % and RMS &lt; 1 mm could be applied. The PA could not be the sole evaluator but complement other parameters for verification.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"235 ","pages":"Article 112825"},"PeriodicalIF":2.8,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multifunctional properties of Mn and Fe co-doped lead-free BCT perovskite ceramics synthesized via solid-state combustion","authors":"Chittakorn Kornphom ,&nbsp;Nutkamon Sonchaopri ,&nbsp;Sununta Yimsabai ,&nbsp;Pongsakorn Jantaratana ,&nbsp;Supree Pinitsoontorn ,&nbsp;Naratip Vittayakorn ,&nbsp;Theerachai Bongkarn","doi":"10.1016/j.radphyschem.2025.112822","DOIUrl":"10.1016/j.radphyschem.2025.112822","url":null,"abstract":"<div><div>There is a growing demand to improve the performance of multiferroic lead-free ceramics. Good ferroelectric and magnetic properties are key parameters for achieving high magnetoelectric coupling (ME). In this work, Mn and Fe were co-doped into lead-free Ba_0.96Ca_0.04Ti_(1-x)(Mn_0.5Fe_0.5)_xO₃ (BCT-xMF) ceramics with 0 ≤ x ≤ 0.030 mol%, synthesized by the solid-state combustion technique. X-ray diffraction (XRD) analysis and Rietveld refinement confirmed the formation of a pure phase with coexisting tetragonal and cubic phases in all compositions. As the Mn/Fe content increased, the percentage of the tetragonal phase decreased while the cubic phase increased, consistent with Raman spectroscopy results. Increasing Mn/Fe content also led to more oxygen vacancies and defects, and a decrease in average grain size. Analysis of the temperature-dependent dielectric constant revealed a reduction in the Curie temperature from 116 to 67 °C, corresponding to the tetragonal-to-cubic phase transformation. The ceramic with x = 0.015 showed the highest dielectric constant at the Curie temperature (ε_c), maximum saturated polarization (P_s), remnant polarization (P_r), saturation magnetization (M_s), and remnant magnetization (M_r), with values of 4583, 14.09 μC/cm², 9.31 μC/cm², 0.0127 emu/g, and 0.006 emu/g, respectively. These results indicate that Fe/Mn co-doping into BCT ceramics enhanced both ferroelectric and ferromagnetic properties, resulting in a high magnetoelectric coefficient (α_ME∼1.27 mV/cm Oe) at room temperature, making these ceramics candidates for multiferroic applications.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"235 ","pages":"Article 112822"},"PeriodicalIF":2.8,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dispersion patterns of scattered radiation exposure on phantom in CT fluoroscopy","authors":"Sook Sam Leong ,&nbsp;Nazarul Azman ,&nbsp;Anushya Vijayananthan ,&nbsp;Jeannie Hsiu Ding Wong","doi":"10.1016/j.radphyschem.2025.112810","DOIUrl":"10.1016/j.radphyschem.2025.112810","url":null,"abstract":"<div><h3>Introduction</h3><div>Working with CT fluoroscopy for diagnoses and therapeutics potentially exposes radiology nurses to ionising radiation. This study aims to estimate the dispersion patterns of scattered radiation doses received by operators during CT fluoroscopy.</div></div><div><h3>Methods</h3><div>An anthropomorphic phantom was exposed to radiation through constant CT fluoroscopy workflow and protocols. Images were obtained per exposure without gantry tilt, 30° gantry tilt in the caudal and 30° in cranial directions. A survey meter was used to detect the scattered radiation doses, which were recorded in millisieverts per hour (mSv/h) with specific distances from the phantom's isocentre in x- (lateral from the isocentre), y- (above the isocentre), and z-directions (anterior and posterior from the isocentre). A survey was conducted to record the most preferred self-positioning of the staff nurses during the procedures. Logarithmic transformation was performed to normalise the measured dose values. The correlation between the radiation dose fall off with distances to the isocentre was evaluated. A generalised linear mixed model (GLMM) was conducted to examine the effects of gantry tilt, height from the floor, and absolute distances from the isocentre on the dose reduction, accounting for variability between the cluster positions.</div></div><div><h3>Results</h3><div>Heatmaps of the dose dispersion pattern were produced, showing that there were moderate negative correlations between scattered radiation and distances to the isocentre. The GLMM analysis showed that gantry tilt, height from the floor, and absolute distance from the isocentre were significant predictors of Log D variation (p &lt; 0.001). Higher Log D values were associated with a 0^o gantry tilt and 30^o cranial tilt, as well as heights of 102 cm and 142 cm compared to 182 cm. Pairwise comparisons indicated significant differences in Log D across gantry tilts and heights, with interaction effects showing a monotonic reduction in Log D from 0° to 30° cranial and caudal tilts, particularly at 142 cm and 182 cm heights. The majority of the staff nurses would station themselves closest to the isocentre during the procedure.</div></div><div><h3>Conclusion</h3><div>This study highlights the influence of gantry tilt, height, and distance from the isocentre on scattered radiation distribution during CT fluoroscopy. The heatmap from this study could be used as a guide for staff nurses to position themselves in the CT room during imaging procedures and support a radiation-safe working environment.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"235 ","pages":"Article 112810"},"PeriodicalIF":2.8,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143853873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dosimetric analysis of magnetic fields impact on 192Ir MicroSelectron-HDR and BEBIG 60Co-HDR brachytherapy sources: A Monte Carlo simulation study using GATE","authors":"Pooya Alvani ,&nbsp;Saman Dalvand ,&nbsp;Mansour Zabihzadeh","doi":"10.1016/j.radphyschem.2025.112814","DOIUrl":"10.1016/j.radphyschem.2025.112814","url":null,"abstract":"<div><div>This study investigates the dosimetric impact of magnetic fields (MFs) on ¹⁹²Ir MicroSelectron-HDR and BEBIG ⁶⁰Co HDR brachytherapy sources. Monte Carlo simulations using the GATE toolkit were conducted to evaluate dosimetric parameters, including radial dose function (g(r)) and anisotropy function (F(r, θ)), as well as dose distributions under MF strengths of 1.5T and 3T across different orientations. The results show that ¹⁹²Ir MicroSelectron-HDR exhibits minimal perturbations in dosimetric parameters, with deviations consistently below 1 %, making it a robust option for MRI-guided brachytherapy. Conversely, ⁶⁰Co sources demonstrate significant dose distortions, with up to 27 % dose enhancement near the source and notable anisotropic effects under MF influence, necessitating MF-specific corrections in treatment planning systems. The results underscore the importance of incorporating MF-induced effects into clinical workflows for MRI-guided brachytherapy, particularly for ⁶⁰Co sources.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"235 ","pages":"Article 112814"},"PeriodicalIF":2.8,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the ill-posed inverse problem in measuring near-threshold electron and positron-induced atomic inner-shell ionization cross-sections based on neural network approaches","authors":"Jiaolong Wu,&nbsp;Ying Wu,&nbsp;Xiaogang Sheng,&nbsp;Yudan Li,&nbsp;Miao Pan","doi":"10.1016/j.radphyschem.2025.112818","DOIUrl":"10.1016/j.radphyschem.2025.112818","url":null,"abstract":"<div><div>Accurate measurement of near-threshold positron or electron impact atomic inner-shell ionization cross-sections is of significant importance both theoretically and in practical applications. Due to the complexity of preparing thin targets, difficulty in precisely measuring their thickness, and the low characteristic X-ray collection efficiency of thin targets in positron collision experiments, the thick-target method is typically employed. Solving the corresponding inner-shell ionization cross-section from the experimental yield of thick targets is an ill-posed inverse problem. Existing methods such as the direct comparison method, yield differential method, and regularization method, do not achieve ideal accuracy. Although our research group has recently developed the MC-neural network method, which significantly improves solution accuracy, it is highly time-consuming to use Monte Carlo simulations to generate neural network datasets. To address this issue, we have developed a numerical-neural network method, which uses numerical calculations to quickly generate large-scale, high-quality datasets for training convolutional neural network models to solve the inverse problem of thick target experimental cross-sections. In this study, numerical-neural network and MC-neural network methods are used to process the experimental yield data of K_ɑβ characteristic X-rays from Ti and L_ɑβγ characteristic X-rays from Ag in positron collisions with pure thick targets at energies below 10 keV. The positron-induced K-shell ionization cross-section of Ti and the L_ɑβγ characteristic X-ray production cross-section of Ag are obtained, which are compared with the experimental cross-sections obtained by the direct comparison method by other researchers and the DWBA theoretical values. The results show that the outcomes obtained by both neural network methods are in good agreement with the results from others and the DWBA theoretical values, and the numerical-neural network method is superior to the MC-neural network method in terms of solution accuracy. In addition, this study also reprocessed the experimental yield data of K_ɑβ characteristic X-rays of Zr and L_ɑβ characteristic X-rays of Au induced by electrons at energies below 27 keV, obtained by Li et al. of Sichuan University using the thick-target method. This also confirmed that the numerical-neural network method has more advantages than other methods.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"235 ","pages":"Article 112818"},"PeriodicalIF":2.8,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Trace Rare Earth (TRE) additions on thermal, crystal structure, and radiation shielding properties of CuAlMn high-temperature S-M alloys: A closer look at Cerium effect","authors":"Ece Kalay ,&nbsp;İskender Özkul ,&nbsp;Oktay Karaduman ,&nbsp;Yasin Kızılgün ,&nbsp;Ömer Güler ,&nbsp;Canan Aksu Canbay ,&nbsp;G. Kilic ,&nbsp;Duygu Sen Baykal ,&nbsp;Ghada ALMisned ,&nbsp;H.O. Tekin","doi":"10.1016/j.radphyschem.2025.112811","DOIUrl":"10.1016/j.radphyschem.2025.112811","url":null,"abstract":"<div><div>This study systematically investigates the effect of Ce addition on the thermal, structural, and radiation shielding properties of CuAlMn-based high-temperature shape memory alloys (HTSMAs). Among the different compositions, Ce-III demonstrated the most balanced performance, exhibiting optimized phase transformation behavior, microstructural refinement, and enhanced gamma-ray attenuation. Differential Scanning Calorimetry (DSC) analysis revealed that Ce-III exhibited lower transformation temperatures, with austenite start (A_s) and finish (A_f) temperatures of 378.13 °C and 429.75 °C, respectively, and martensite start (M_s) and finish (M_f) temperatures of 402.52 °C and 341.91 °C, suggesting improved thermal stability. Microstructural analysis indicated significant grain refinement, attributed to Ce's dislocation pinning effect, which contributed to enhanced strength and radiation attenuation. X-ray diffraction (XRD) patterns confirmed the formation of Ce-rich intermetallic phases, such as Mn_1.15Cu_3.85Ce and Cu₈Ce₄, which increased density and photon interaction probability. The Ce-III alloy exhibited superior linear attenuation coefficients and reduced half-value layer, reinforcing its effectiveness as a radiation shielding material. It can be concluded that Ce-III represents an optimal composition with a synergistic combination of structural stability, phase transformation control, and enhanced radiation shielding capabilities, making it a promising candidate for nuclear and high-radiation applications.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"234 ","pages":"Article 112811"},"PeriodicalIF":2.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uranium recovery from Moroccan Phosphate rock for nuclear-powered desalination and water security: A review","authors":"Fatima Ezzahra Arhouni ,&nbsp;Maged Ahmed Saleh Abdo ,&nbsp;Saad Ouakkas ,&nbsp;Mohamed Lhadi Bouhssa ,&nbsp;Aziz Boukhair","doi":"10.1016/j.radphyschem.2025.112802","DOIUrl":"10.1016/j.radphyschem.2025.112802","url":null,"abstract":"<div><div>Morocco faces severe water scarcity, making nuclear-powered desalination a promising solution. With 50 billion tonnes of phosphate reserves containing 6.9 million tonnes of uranium, Morocco holds the largest unconventional uranium resource, offering a sustainable uranium supply. This review examines uranium recovery from wet-process phosphoric acid (WPA) using solvent extraction, ion exchange, and membrane-based methods, highlighting their efficiency and applicability. The feasibility of integrating uranium recovery with Morocco's phosphate industry is assessed, emphasizing its role in supporting domestic nuclear energy production. Additionally, the study explores the economic viability of nuclear desalination, demonstrating its potential to ensure long-term water and energy security. Policy and regulatory frameworks are discussed to advance uranium recovery and nuclear desalination efforts. Findings suggest that leveraging phosphate-derived uranium could position Morocco as a key player in the global nuclear fuel cycle while reinforcing sustainable water management.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"234 ","pages":"Article 112802"},"PeriodicalIF":2.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143826287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Point Dose Verification in Delivery Quality Assurance for Gyroscopic Radiosurgery System","authors":"Yagiz Yedekci ,&nbsp;Huseyin Kıvanc ,&nbsp;Fatih Biltekin ,&nbsp;Demet Yildiz ,&nbsp;Gozde Yazici ,&nbsp;Gokhan Ozyigit","doi":"10.1016/j.radphyschem.2025.112798","DOIUrl":"10.1016/j.radphyschem.2025.112798","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to evaluate the feasibility and accuracy of patient-specific delivery quality assurance (PS-DQA) using the Semiflex®3D ionization chamber within the ZAP-X gyroscopic radiosurgery system.</div></div><div><h3>Materials and Methods</h3><div>PS-DQA measurements were performed on 110 patients with 184 lesions treated using the ZAP-X system. Target volumes ranged from 11 mm³ to 63,044 mm³, with a mean of 4,321 mm³. Treatment plans were developed using the ZAP-X Treatment Planning System (TPS), which utilizes a ray-tracing algorithm for dose calculation. PS-DQA was conducted using a water-equivalent spherical phantom and the Semiflex®3D ionization chamber. The phantom was scanned with 0.625 mm CT slice thickness, and treatment plans were recalculated on the phantom’s CT dataset. The percentage differences between measured and planned doses were analyzed, focusing on different target volume categories and the use of small collimators (4 mm and 5 mm). Statistical analysis assessed the significance of observed differences.</div></div><div><h3>Results</h3><div>Most PS-DQA measurements (84%) showed discrepancies between -5% and +5% compared to planned doses. However, smaller target volumes (0-500 mm³) exhibited significantly higher percentage differences, highlighting challenges in dose measurement accuracy for these fields. Greater dose discrepancies were also observed when small collimators were extensively used, particularly when their usage exceeded 75% of total isocenters. Tukey HSD tests confirmed statistically significant differences between groups based on target volume and collimator size.</div></div><div><h3>Conclusion</h3><div>The study confirms the feasibility of PS-DQA with the Semiflex®3D ionization chamber in the ZAP-X system while highlighting challenges with small target volumes and extensive use of small collimators.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"234 ","pages":"Article 112798"},"PeriodicalIF":2.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}