Psychiatry and Clinical Psychopharmacology最新文献

{"title":"Multi-Modal Motion-Assisted Memory Desensitization and Reconsolidation (3MDR) Treatment for Postpartum Posttraumatic Stress Disorder (PTSD) from Grief: A Case Report.","authors":"Suzette Brémault-Phillips, Katherine Bright, Katie Allen, Judy Kim, Sarah Mouallem, Lily Strybosch, Eric Vermetten, Phillip R Sevigny","doi":"10.5152/pcp.2025.241034","DOIUrl":"10.5152/pcp.2025.241034","url":null,"abstract":"<p><p>The well-being of postpartum mothers can be significantly affected by posttraumatic stress disorder (PTSD) and grief. Success with standard PTSD interventions for this population has been inconsistent. Multi-modal motion-assisted memory desensitization and reconsolidation therapy (3MDR) is an intervention that has been studied favorably with military and veteran populations with PTSD and related conditions. Minimal research is available, however, regarding its application in the civilian population. This case report investigates the use of 3MDR in facilitating trauma and grief processing and reducing PTSD symptoms in a 35-year-old postpartum mother with treatment-resistant PTSD and grief undergoing 3MDR. Qualitative data collected throughout the 3MDR intervention and at the 3-, 6-, and 10-month follow-ups were thematically analyzed. The participant reported feeling increased control over her life after 3MDR and reduced adverse reactions to normally distressing events. During the follow-up sessions, the overarching trauma process was one of peeling back layers of her experiences. The following 3 themes emerged: gaining control in chaos, shifting from an ideal to a real perspective, overcoming trauma and moving forward in life. This case report suggests that 3MDR's immersive, motion-assisted, patient-centered psychotherapeutic approach and strong therapeutic relationship facilitated unique trauma and grief processing, empowering meaningful progress where prior interventions had failed.</p>","PeriodicalId":20847,"journal":{"name":"Psychiatry and Clinical Psychopharmacology","volume":"35 Suppl 1","pages":"S168-S175"},"PeriodicalIF":0.6,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are Equine Assisted Interactions (EAI) a Dark Horse Bet? A Systematic Review on Measuring the Psychological and Physiological Effects of EAI on PTSD, Anxiety and/or Mood Disorders.","authors":"Chantal Kapteijn, Nadieh Reinders, Martine Hueting, Rogier Alexander Van Huffelen, Eric Vermetten, Bas Rodenburg, Nienke Endenburg","doi":"10.5152/pcp.2025.24958","DOIUrl":"10.5152/pcp.2025.24958","url":null,"abstract":"<p><p>Background: Conventional forms of trauma-focused psychological interventions seem to be less effective in military veterans with post-traumatic stress disorder (PTSD). Equine Assisted Interventions (EAI) have become increasingly popular as an additional treatment, resulting in increasing research on the effects of EAI. However, no systematic review on the effects of EAI has focused on PTSD, anxiety and/or mood disorders and whether the effects are reflected in psychological and physiological measures. This systematic review investigated the treatment effects, study design, population, intervention, and psychological and physiological measurements in EAI research. Methods: The search strategy yielded 1028 original articles from 3 electronic databases: PubMed, Scopus, and CAB Abstracts. These articles were screened by 2 individual blinded researchers with Rayyan according to Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines and rendered 31 eligible studies. Results: Although all quantitative studies reported 1 or more positive treatment effects on symptoms of PTSD, anxiety and/or mood disorders, well-designed studies were sparse. This review demonstrated a lack of methodological information and few randomized controlled studies, in addition to a large heterogeneity in population characteristics, interventions, terminology, and questionnaires. Conclusion: Future studies should address these methodological considerations in order to advance the understanding of EAI and optimize their efficacy in treating PTSD, anxiety and/or mood disorders.</p>","PeriodicalId":20847,"journal":{"name":"Psychiatry and Clinical Psychopharmacology","volume":"35 Suppl 1","pages":"S90-S112"},"PeriodicalIF":0.6,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interventional Psychiatry and Emerging Treatments for Posttraumatic Stress Disorder (PTSD): A Systematic Review.","authors":"Reinhard Janssen-Aguilar, Shakila Meshkat, Huda F Al-Shamali, Argyrios Perivolaris, Jennifer Swainson, Yanbo Zhang, Andrew Greenshaw, Lisa Burback, Olga Winkler, Jennifer L Phillips, Murray W Enns, Jitender Sareen, Andrew Nicholson, Eric Vermetten, Rakesh Jetly, Ruth Lanius, Venkat Bhat","doi":"10.5152/pcp.2025.241027","DOIUrl":"10.5152/pcp.2025.241027","url":null,"abstract":"<p><strong>Background: </strong>Posttraumatic stress disorder (PTSD) is a severe, often difficult-to-treat condition, highlighting the need for innovative therapies. Interventional treatments, including neuromodulation, rapid-acting pharmacotherapies such as intravenous ketamine (IV-KET) and esketamine (ESK), and emerging psychedelic-assisted psychotherapies, offer promising solutions. This systematic review evaluates the efficacy, safety, and future research priorities of these treatments for PTSD.</p><p><strong>Methods: </strong>A search strategy was implemented across 3 electronic databases. Peer-reviewed articles written in English that focused on interventional psychiatry treatments for adult patients with PTSD were included.</p><p><strong>Results: </strong>The systematic review encompassed 94 studies, including 39 on transcranial magnetic stimulation (TMS), 8 on IV-KET, 3 on intranasal esketamine (IN-ESK), 4 on intravenous ketamine (IV-KET) assisted therapy (KET-AT), 1 on esketamine (ESK) assisted therapy (ESK-AT), and 14 on 3,4-methylenedioxymethamphetamine assisted therapy (MDMA-AT). Randomized controlled trials demonstrated response rates of 12.5%-80% for TMS, 17%-67% for IV-KET, and 50%-87% for MDMA. Additional treatments reviewed included Electroconvulsive Therapy, transcranial direct current stimulation, and other pharmacological and neurostimulation treatments. Most treatments were well tolerated, with only mild, transient adverse effects.</p><p><strong>Conclusions: </strong>This review highlights the heterogeneity in efficacy, safety, and tolerability across neuromodulation and pharmacologic treatments for PTSD. Variability in response rates reflects differences in patient populations, protocols, and comorbidities. While repetitive TMS, IV-KET, ESK, KET-AT, and MDMA-AT show symptom improvement, sustained efficacy varies, underscoring the need for maintenance strategies. Although direct evidence on stage-specific approaches is limited, these methods, guided by neuroscience-based nomenclature, may improve therapeutic precision, especially in complex cases.</p>","PeriodicalId":20847,"journal":{"name":"Psychiatry and Clinical Psychopharmacology","volume":"35 Suppl 1","pages":"S57-S89"},"PeriodicalIF":0.6,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Potential of Personalized Post-Traumatic Stress Disorder Networks.","authors":"Floor van der Does, Masanori Nagamine, Masato Kitano, Taku Saito, Nic van der Wee, Eric Vermetten, Erik Giltay","doi":"10.5152/pcp.2025.251059","DOIUrl":"10.5152/pcp.2025.251059","url":null,"abstract":"<p><p>Addressing the spectrum of mental health requires innovative methods. Network theory views psychopathological symptoms as complex dynamic systems, potentially allowing for the identification of better monitoring and intervention targets. This article advocates for the Dynamic Time Warping (DTW) algorithm to construct symptom networks, building on two recent studies on Post-Traumatic Stress Disorder (PTSD). The studies used a cohort of 55,632 Japan Ground Self-Defense Force personnel who completed the Impact of Event Scale-Revised annually from 2013 to 2018. The first study applied DTW to create symptom networks for individuals with significant PTSD symptoms (IES-R ≥ 25, n = 1,120). The second study analyzed dynamic symptom networks in four PTSD symptom trajectories (cumulative IES-R > 5, n = 10,211), generating temporal lead and -lag profiles to reflect symptom improvement and worsening. The first study identified four PTSD symptom clusters, yielding evidence for a new dissociation cluster. In the second study, lower network density in undirected DTW analyses was associated with chronic PTSD. Directed analyses showed that dissociation symptoms decreased first during recovery, while emotional reactivity persisted. Conversely, in worsening PTSD avoidance symptoms escalated first, while dissociation symptoms intensified last. These findings demonstrate the potential of DTW as a tool for constructing interpretable networks that capture the complex dynamics of psychological processes. This approach could enhance our understanding and treatment of a wide range of mental health conditions. Future research should further explore its applications to enable more personalized and effective mental health interventions.</p>","PeriodicalId":20847,"journal":{"name":"Psychiatry and Clinical Psychopharmacology","volume":"35 Suppl 1","pages":"S141-S151"},"PeriodicalIF":0.6,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Validation and Cultural Adaptation of the Turkish Version of the Global Psychotrauma Screen.","authors":"Mihriban Heval Özgen, Chris Hoeboer, Cato M H de Vos, Tuğba Türk-Kurtça, Miranda Olff, Vedat Şar","doi":"10.5152/pcp.2025.24984","DOIUrl":"10.5152/pcp.2025.24984","url":null,"abstract":"<p><p>Background: The prevalence of trauma-related disorders in Türkiye is higher than in high-income countries due to an increased likelihood of exposure to traumatic events. Türkiye's high prevalence of trauma-related disorders underscores the need for validated tools to screen for trauma-related symptoms. The Global Psychotrauma Screen (GPS) is a newly developed, brief instrument designed to screen for transdiagnostic trauma-related symptoms and risk factors. However, its validity in Turkish populations has yet to be established. This study aimed to evaluate the psychometric properties of the Turkish version of the GPS in a general population sample from Türkiye. Methods: The Turkish version of the GPS was administered digitally to 499 individuals (36.3% male, 63.7% female) aged 18 to 74 years (mean ± SD = 24.58 ± 9.26). Psychometric analyses included exploratory factor analysis, internal consistency, reliability, clinical validity, and convergent-divergent validity. Specific statistical tests such as Cronbach's alpha for internal consistency and confirmatory factor analysis for validity were conducted. Convergent-divergent validity was assessed using correlations with other established measures of trauma symptoms, such as the posttraumatic stress disorder (PTSD) Checklist (PCL). Linear regression examined associations between risk factors and trauma-related symptoms. Results: Exploratory factor analysis indicated a single-factor structure for trauma-related symptoms. The GPS showed strong internal consistency (α = 0.87) and reliability. Clinical validity was moderate with cut-off scores of 3 for probable PTSD and 2 for depression and anxiety. These cut-off scores resulted in high sensitivity but low specificity. Risk factors such as low social support, childhood trauma, a history of mental illness, and exposure to other stressful events were significantly associated with higher GPS symptoms. The convergent validity analysis indicated a significant correlation with the PTSD Checklist (PCL), showing convergence (r = 0.48, P < .01). Conclusion: The Turkish version of the GPS is a valid and reliable screening tool for trauma-related symptoms and provides a quick and efficient screening process. However, clinical interviews are recommended following GPS screening to confirm diagnoses. These findings support the Turkish GPS as a rapid and culturally adaptable screening tool for trauma-related symptoms, although confirmatory clinical interviews remain essential for diagnosis. These findings support the applicability of GPS across diverse cultural contexts. Further studies are needed to explore its psychometric properties in other regions and languages.</p>","PeriodicalId":20847,"journal":{"name":"Psychiatry and Clinical Psychopharmacology","volume":"35 Suppl 1","pages":"S36-S46"},"PeriodicalIF":0.6,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic Stress Disorder Psychopharmacology Algorithm Update-2024-2025.","authors":"Laura A Bajor, Charmi Balsara, David N Osser","doi":"10.5152/pcp.2025.241041","DOIUrl":"10.5152/pcp.2025.241041","url":null,"abstract":"<p><p>Since the last publication of the Psychopharmacology Algorithm Project at the Harvard South Shore Program Posttraumatic Stress Disorder (PTSD) algorithm in 2022, additional evidence has reinforced key treatment recommendations. Prazosin remains the first-line treatment for PTSD-related sleep impairment, including nightmares and disturbed awakenings, and it may be useful for individuals with comorbid alcohol use disorder and comorbid headaches. After treating PTSD insomnia, if significant daytime symptoms remain, a selective serotonin reuptake inhibitor ( SSRI, sertraline or paroxetine are suggested), and this may be augmented by an antipsychotic (consider aripiprazole first) if psychotic symptoms, if any, do not respond to the SSRI. If results are still unsatisfactory, a second SSRI or a selective norepinephrine reuptake inhibitor (SNRI) could be considered, though they offer no benefit for hyperarousal symptoms, and prazosin may also be tried for residual daytime symptoms. This update also evaluates emerging treatments, including transcranial magnetic stimulation, direct current stimulation, stellate ganglion block, and pimavanserin, though concluding that current evidence does not yet warrant their inclusion in the core algorithm. This update provides clinicians with an evidenceinformed approach to pharmacological PTSD management based on the latest available data.</p>","PeriodicalId":20847,"journal":{"name":"Psychiatry and Clinical Psychopharmacology","volume":"35 Suppl 1","pages":"S135-S140"},"PeriodicalIF":0.6,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic Stress Disorder-Related Mental Health Problems and Risk Factors After an Earthquake.","authors":"Tamer Aker, Ece Önder","doi":"10.5152/pcp.2025.24997","DOIUrl":"10.5152/pcp.2025.24997","url":null,"abstract":"<p><p>Earthquakes can have a substantial impact on communities, leading to severe economic losses, structural damage, casualties, and displacement, as well as adverse psychological effects on survivors. Previous studies have highlighted a broad spectrum of adverse psychological effects following disasters, such as sleep disturbances, emotional distress, depression, suicidal thoughts, anxiety, posttraumatic stress disorder (PTSD). Posttraumatic stress disorder is particularly common among disaster survivors. It is characterized by the emergence of specific symptoms following direct exposure (experiencing a traumatic event firsthand or witnessing it happen to others) or indirect exposure (learning about a traumatic event involving loved ones or repeatedly being exposed to distressing details of the event). Disasters, crises, and traumas are difficult life experiences that require individuals to seek support. It is crucial to identify key factors such as individuals' location, emotional state, and their specific needs during these times to provide effective assistance. Addressing these aspects is essential in preventing trauma from worsening or becoming more entrenched. Post-earthquake psychosocial support should include comprehensive, long-term, and sustainable interventions to improve the mental health of both individuals and society. The aim of this article is to evaluate PTSD and related mental health issues following earthquakes.</p>","PeriodicalId":20847,"journal":{"name":"Psychiatry and Clinical Psychopharmacology","volume":"35 Suppl 1","pages":"S113-S121"},"PeriodicalIF":0.6,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motion-Assisted, Multi-Modal Memory Desensitization and Reconsolidation Therapy for Posttraumatic Stress Disorder in Women with a History of Sexual Trauma.","authors":"Paula Bellini, Annabel Lee Raboy, Adele Fu, Thaddeus Haight, Eric Vermetten, Michael J Roy","doi":"10.5152/pcp.2025.24996","DOIUrl":"10.5152/pcp.2025.24996","url":null,"abstract":"<p><p>Background: Women military service members (SMs) are more likely to have posttraumatic stress disorder (PTSD) related to sexual assault, highlighting a need for the development and validation of therapies. A new exposure-based therapy called motion-assisted, multi-modal memory desensitization and reconsolidation (3MDR) uses participant-chosen music and images and an eye movement (EM) task in a virtual environment. Motion-assisted, multi-modal memory desensitization and reconsolidation has shown effectiveness in treating treatment-resistant male veterans; thus, this paper focuses expressly on the utility of 3MDR in female study participants, who were 50% of the full study population. Methods: Participants with probable PTSD and mild traumatic brain injury (mTBI) completed 10 sessions of 3MDR. They provided songs and images representative of their trauma(s). While walking on a treadmill, participants confronted up to 7 of their trauma images while keywords were superimposed over the images. Half the participants were randomized to an eye movement task (EM+). The primary outcome was the change in posttraumatic stress disorder checklist for DSM-5 (PCL-5) score from pre- to post-intervention, with 3- and 6-month follow-ups. Results: All women participants had a history of sexual trauma and showed statistically and clinically significant improvement in symptom severity. The decline in mean PCL-5 scores was greater for women than for men (none of whom reported sexual trauma), though the difference was not statistically significant. Although a small sample size, the results suggest clinically meaningful sex differences. Conclusion: Motion-assisted, multi-modal memory desensitization and reconsolidation is an effective and powerful intervention for female SMs and veterans with a history of sexual trauma. Further investigation with larger sample sizes is needed.</p>","PeriodicalId":20847,"journal":{"name":"Psychiatry and Clinical Psychopharmacology","volume":"35 Suppl 1","pages":"S20-S28"},"PeriodicalIF":0.6,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspectives on Trauma Treatment, Self-Management Strategies, and Attitudes Toward Psychedelic Therapies in Individuals with Psychological Trauma Symptoms.","authors":"Nadav Liam Modlin, Maples-Keller Jessica L, Maria Sarang, Lucie Siebenaler, Carolina Maggio, Susannah Pick, Victoria Williamson, Anthony Cleare, James Rucker","doi":"10.5152/pcp.2025.24934","DOIUrl":"10.5152/pcp.2025.24934","url":null,"abstract":"<p><p>Background: Current trauma treatment options often fail to meet patients' needs. Despite the availability of established interventions, many trauma treatments fail to adequately meet patients' needs. In parallel, there has been renewed scientific and public interest in the therapeutic potential of psychedelics and related compounds, accompanied by increasing unsupervised use. This underscores the need to examine patients' willingness to engage with these therapies should they receive regulatory approval and to better characterize patterns of self-administration in order to inform patient-centered care and harm reduction strategies. Methods: An online survey recruited individuals with self-reported trauma symptoms or a formal diagnosis of post-traumatic stress disorder (PTSD)/complex post-traumatic stress disorder (CPTSD). Participants were asked about their treatment history, satisfaction with current treatments, and use of illicit substances for symptom management. Further, after receiving psychoeducation on 3,4-methylenedioxymethamphetamine (MDMA) and psilocybin therapies, participants' perceptions and willingness to participate in these treatments were assessed. Results: Of the 873 respondents, 94.8% reported experiencing psychological trauma, with 73.4% diagnosed with PTSD or CPTSD. Many had attempted multiple treatments, predominantly medications and various psychotherapies, but reported high dissatisfaction. Significant rates of marijuana, psychedelics, and MDMA use for self-management of trauma symptoms were reported, with minimal physical and psychological complications. Willingness to try MDMA and psilocybin therapies was high (0.81 and 0.83, respectively). Notably, women and heterosexual individuals showed lower willingness, while younger respondents and those with higher education levels showed greater willingness to try these treatments. Conclusion: High willingness to try MDMA and psilocybin therapies among trauma-exposed individuals highlights the need for further research and clinical trials. Understanding demographic variations in willingness can guide the development of accessible and effective treatment options for PTSD and CPTSD. Public education about potential risks and harm reduction strategies is crucial to promote safe and informed use of these emerging therapies.</p>","PeriodicalId":20847,"journal":{"name":"Psychiatry and Clinical Psychopharmacology","volume":"35 Suppl 1","pages":"S3-S19"},"PeriodicalIF":0.6,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144966497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Adolescents with Anxiety Disorders in the Context of Cognitive Distortion.","authors":"Ezgi Karagöz Tanıgör, Gonca Özyurt, Yusuf Öztürk, Ali Evren Tufan, Aynur Akay","doi":"10.5152/pcp.2025.241047","DOIUrl":"10.5152/pcp.2025.241047","url":null,"abstract":"<p><p>Background: This study aimed to investigate the differences in cognitive distortions between patients with anxiety disorder (AD) and healthy controls, investigate the relationship between anxiety levels and cognitive distortions in AD, and investigate whether accompanying symptoms in AD had an impact on cognitive distortions Methods: Eighty-nine adolescents diagnosed with AD and 94 healthy adolescents were assessed using The Kiddie Schedule for Affective Disorders and Schizophrenia, Screen for Child Anxiety Related Emotional Disorders (SCARED), Beck Depression Inventory (BDI), Cognitive Distortions Scale (CDS), and the effects of major depressive disorder (MDD) were evaluated. Results: All cognitive distortions except catastrophizing were more problematic in AD. It also assessed the effects of comorbid MDD with AD on cognitive distortions. Another finding that was obtained in this study was that thought characteristics such as mindreading, catastrophizing, all-or-nothing thinking, emotional reasoning, personalization, minimizing the positive, and overgeneralization, CDS total scores were statistically significantly higher in the AD group with comorbid MDD. Conclusion: The study indicates that some cognitive distortions may be prevalent in AD or AD with comorbid depression. The importance of this study is the probability of laying the groundwork for future research in adolescents, the development of cognitive anxiety models, and guiding treatment practices.</p>","PeriodicalId":20847,"journal":{"name":"Psychiatry and Clinical Psychopharmacology","volume":"35 3","pages":"226-233"},"PeriodicalIF":0.6,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12371742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}