Progress in neuro-psychopharmacology最新文献_第4页

An investigation of the interaction between the reinforcing properties of food and ethanol using the place preference paradigm 利用位置偏好范式研究食物和乙醇强化特性之间的相互作用

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 DOI: 10.1016/0364-7722(81)90057-6

Robert B. Stewart, Larry A. Grupp

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引用次数: 50

Anxiety states, phobic and obsessive-compulsive disorders. Clinical picture, differential diagnostic and management 焦虑状态，恐惧症和强迫症。临床表现、鉴别诊断及处理

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 DOI: 10.1016/0364-7722(81)90067-9

Isaac M. Marks

引用次数: 2

Predicting stimulant effectiveness in hyperactive children with a repeatable neuropsychological battery: A preliminary study 用可重复的神经心理学电池预测多动症儿童的兴奋剂有效性:一项初步研究

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 DOI: 10.1016/0364-7722(81)90006-0

Barry E. Golinko, Phillip M. Rennick, Ronald F. Lewis

引用次数: 4

The prolactin response in patients receiving neuroleptic therapy. The effect of fluphenazine decanoate 接受抗精神病药物治疗患者的催乳素反应。癸酸氟非那嗪的作用

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 DOI: 10.1016/0364-7722(81)90007-2

Andrea Dotti , Onofrio Lostia , Ivo A. Rubino , Giuseppe Bersant , Luciana Carilli , Domenico Zorretta

{"title":"The prolactin response in patients receiving neuroleptic therapy. The effect of fluphenazine decanoate","authors":"Andrea Dotti , Onofrio Lostia , Ivo A. Rubino , Giuseppe Bersant , Luciana Carilli , Domenico Zorretta","doi":"10.1016/0364-7722(81)90007-2","DOIUrl":"10.1016/0364-7722(81)90007-2","url":null,"abstract":"<div><ul><li>1.1. Fluphenazine decanoate (FD) 50 mg was administered to 15 patients. The patient population was divided into three groups: i) Group A including 5 subjects who had never been treated before; ii) Group B including 5 subjects treated with neuroleptics for at least one year, but who had discontinued the drugs for at least three months and iii) Group C including 5 subjects who had been chronically treated with neuroleptics for at least two years.</li><li>2.2. The increase in plasma level of the hormone prolactin (PRL) after the administration of FD was different in the three groups. The patients never treated before showed the highest “PRL response”, which had a great variability among all patients.</li><li>3.3. The “PRL response” did not correlate neither with psychopathological changes nor with extrapyramidal side effects.</li><li>4.4. The “PRL response” did not seem to be a useful tool in predicting the appropriate dosage and interval of the FD administration in a given patient.</li></ul></div>","PeriodicalId":20801,"journal":{"name":"Progress in neuro-psychopharmacology","volume":"5 1","pages":"Pages 69-77"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0364-7722(81)90007-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18293370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Clinical detection and assessment of drug induced neurotoxicity 药物致神经毒性的临床检测与评价

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 DOI: 10.1016/0364-7722(81)90024-2

Claudio A. Naranjo , Luis Fornazzari , Edward M. Sellers

{"title":"Clinical detection and assessment of drug induced neurotoxicity","authors":"Claudio A. Naranjo , Luis Fornazzari , Edward M. Sellers","doi":"10.1016/0364-7722(81)90024-2","DOIUrl":"10.1016/0364-7722(81)90024-2","url":null,"abstract":"<div><ul><li>1.1. Drug-induced neurological disease is a relatively common problem. For example, the Boston Collaborative Drug Surveillance Program reported that in 11,526 hospitalized patients, 14.2% of adverse drug reactions (ADRs) were neurological.</li><li>2.2. Drugs can induce various syndromes such as: disturbances of consciousness, psychiatric disorders, headache, cranial nerve disorders, movement disorders, psychosis, peripheral neuropathy, myopathy and autonomic dysfunction.</li><li>3.3. The vast majority of ADRs are dose-related (e.g. CNS depression by sedative-hypnotics). In these cases the frequency and severity of the ADRs is proportional to the administered dose, therefore, they can be prevented and/or treated by adjusting the dosage to patient's needs. Dose-unrelated ADRs (e.g. malignant hyperthermia by various anaesthetic agents) are uncommon and the development of the reaction is mainly dependent on increased patient's susceptibility. Accordingly, the ADR can only be prevented by not readministering the drug.</li><li>4.4. Most of the evidence associating specific drugs with neurological adverse events comes from single case reports in which no systematic assessment of causality has been made. Recently, valid and reliable definitions of ADRs have been reported (e.g. Kramer et al, 1979; Naranjo et al, 1981). The systematic application of these methods greatly reduce the ambiguity for analyzing alleged cases of ADRs. These methods can be easily applied by practising physicians in the assessment and reporting of suspected drug-induced neurological diseases.</li></ul></div>","PeriodicalId":20801,"journal":{"name":"Progress in neuro-psychopharmacology","volume":"5 5","pages":"Pages 427-434"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0364-7722(81)90024-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17342640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

An EEG analysis of convulsive activity produced by cholinergic agents 胆碱能药物引起的惊厥活动的脑电图分析

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 DOI: 10.1016/0364-7722(81)90089-8

Steven L. Cohen , Barbara J. Morley , O.Carter Snead

引用次数: 31

Clinical pharmacology of senile dementia 老年性痴呆的临床药理学

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 DOI: 10.1016/0364-7722(81)90026-6

M. Fisman

引用次数: 7

News and intercommunications in neuro-psychopharmacology 神经精神药理学的新闻与交流

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 DOI: 10.1016/0364-7722(81)90095-3

引用次数: 0

A comparative study of the therapeutic effect and cardiotoxicity of dothiepin HC1 and doxepin HC1 in reactive depression 多硫平HC1与多硫平HC1治疗反应性抑郁症的疗效及心脏毒性比较研究

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 DOI: 10.1016/0364-7722(81)90090-4

Larry Evans, John Cox

引用次数: 2

Effect of chronic treatment with haloperidol on serum prolactin, striatal opiate receptors and β-endorphin content in rat brain and pituitary 氟哌啶醇慢性治疗对大鼠血清催乳素、纹状体阿片受体及脑垂体β-内啡肽含量的影响

Progress in neuro-psychopharmacology Pub Date : 1981-01-01 DOI: 10.1016/0364-7722(81)90044-8

Nobumasa Kato, Kanhaiya R. Shah, Henry G. Friesen, Viktor Havlicek

{"title":"Effect of chronic treatment with haloperidol on serum prolactin, striatal opiate receptors and β-endorphin content in rat brain and pituitary","authors":"Nobumasa Kato, Kanhaiya R. Shah, Henry G. Friesen, Viktor Havlicek","doi":"10.1016/0364-7722(81)90044-8","DOIUrl":"https://doi.org/10.1016/0364-7722(81)90044-8","url":null,"abstract":"<div><ul><li>1.1. Rats were treated for 21 days with haloperidol (2mg/kg/day) and prolactin levels were measured serially. The increase in prolactin was obvious throughout the treatment and was even more prominent after repeated injections.</li><li>2.2. Immunoreactive β-endorphin levels were increased in the pituitary, whereas decreased in N. accumbens in rats chronically treated with haloperidol. The opiate receptor binding in the striatum showed no change in treated rats as compared with controls.</li><li>3.3. The present study suggests that 1) tolerance does not develop in prolactin-increasing action of haloperidol; 2) dopamine receptors have a role in the control of immunoreactive β-endorphin in some brain areas; 3) the various dopaminergic pathways in the brain respond differently to chronic treatment with haloperidol in terms of immunoreactive β-endorphin regulation.</li></ul></div>","PeriodicalId":20801,"journal":{"name":"Progress in neuro-psychopharmacology","volume":"5 5","pages":"Pages 549-552"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0364-7722(81)90044-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91756680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9