Przegla̜d Gastroenterologiczny最新文献_第8页

Impact of cefixime and probiotics on functional abdominal bloating: a pilot study. 头孢克肟和益生菌对功能性腹胀的影响：一项初步研究。

IF 1.7

Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2024-12-02 DOI: 10.5114/pg.2024.142141

Rasha I Salama, Salwa Tawfik, Mohamed H Emara, Abeer H Abdelkader

{"title":"Impact of cefixime and probiotics on functional abdominal bloating: a pilot study.","authors":"Rasha I Salama, Salwa Tawfik, Mohamed H Emara, Abeer H Abdelkader","doi":"10.5114/pg.2024.142141","DOIUrl":"10.5114/pg.2024.142141","url":null,"abstract":"Introduction: Abdominal bloating is a prevalent condition that affects up to 30% of the population.Aim: Investigate the impact of cefixime and probiotics on the bloating sensation among patients with functional abdominal bloating (FAB).Material and methods: Out of 763 patients with bloating, 122 patients were diagnosed with FAB. Group I (n = 40) were treated with a combination of non-activated herbal charcoal and silicone dioxide with dimethylpolysiloxane (conventional treatment group); group II (n = 41) were treated by the same lines as in group I with the addition of cefixime 400 mg once daily for 6 days; and group III (n = 41) were treated by the same lines given to group I with the addition of a probiotic formulation harbouring the probiotic strain Lactobacillus helveticus candisis for 2 weeks. All patients were evaluated by history taking, clinical examination, laboratory assessment, relevant imaging, and symptom questionnaire before and by the end of treatment.Results: The prevalence of FAB was 15.9% (122/763). The majority were females (58.1%). Patients treated with probiotics and cefixime reported significant improvement in the sense of bloating and the visible abdominal distension in comparison to conventional treatment (p = 0.008 and < 0.001, respectively). Abdominal pain, belching, bowel habit change, and nausea improved and were comparable among the 3 groups by the end of treatment. No adverse events related to the used medications were observed.Conclusions: Cefixime and probiotics exert significant improvement in the subjective sensation of bloating and objective abdominal distension among patients with FAB in comparison to conventional anti-flatulence therapy.","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"16 4","pages":"408-415"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Direct peroral cholangioscopy combined with argon plasma and radio-frequency ablation in restoring the patency of a self-expandable metal stent. 直接经口胆道镜联合氩等离子体和射频消融修复自膨胀金属支架的通畅。

IF 1.7

Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2024-09-23 DOI: 10.5114/pg.2024.143165

Tomasz Klimczak, Jacek Śmigielski

引用次数: 0

Resistance to death pathway induction as a potential targeted therapy in CRISPR/Cas-9 knock-out colorectal cancer cell lines. 在 CRISPR/Cas-9 基因敲除的结直肠癌细胞系中，死亡通路诱导作为一种潜在的靶向疗法具有抗药性。

IF 1.7

Przegla̜d Gastroenterologiczny Pub Date : 2024-01-01 Epub Date: 2024-02-05 DOI: 10.5114/pg.2024.134872

Malgorzata Adamiec-Organisciok, Magdalena Wegrzyn, Lukasz Cienciala, Ngoni Magate, Magdalena Skonieczna, Joanna Nackiewicz

{"title":"Resistance to death pathway induction as a potential targeted therapy in CRISPR/Cas-9 knock-out colorectal cancer cell lines.","authors":"Malgorzata Adamiec-Organisciok, Magdalena Wegrzyn, Lukasz Cienciala, Ngoni Magate, Magdalena Skonieczna, Joanna Nackiewicz","doi":"10.5114/pg.2024.134872","DOIUrl":"https://doi.org/10.5114/pg.2024.134872","url":null,"abstract":"Regulated cell death is a fundamental biological process that plays a crucial role in maintaining tissue homeostasis and eliminating damaged or unnecessary cells. Ferroptosis is an iron-dependent process, characterized by the accumulation of oxidized and damaged lipids, which leads to programmed cell death. Among the ferroptotic pathway genes regulating this process, GPX4, TFRC, ACSL4, FSP1, SLC7A11, and PROM2 could be considered. There are many well-known ferroptotic pathway regulators, which are discussed in this compact review. Cells with tissues of different origin display sensitive or resistant phenotypes to such regulators. In some cases, unexpected changes during cell treatment occurred, suggesting the possibility of regulating the death pathway. We assumed that possible changing of ferro-sensitivity to ferro-resistance in cells, especially in colorectal cancer cell lines, is responded for induced chemoresistance. Using novel techniques, such as CRISPR/Cas-9 genome editing, an induced phenotype \"switching\" is possible.","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 2","pages":"112-120"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11200076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of ASF1B as a prognostic marker for liver cancer by meta-analysis and its immune value revealed by a comprehensive pan-cancer analysis of 33 human cancersrevealed by a comprehensive pan-cancer analysis of 33 human cancers 通过荟萃分析鉴定ASF1B作为肝癌预后标志物，并通过对33例人类癌症的综合泛癌分析揭示其免疫价值

IF 1.3

Przegla̜d Gastroenterologiczny Pub Date : 2023-01-23 DOI: 10.5114/pg.2023.124423

Yiyang Chen, Wanbang Zhou, Yiju Gong, Xi Ou

{"title":"Identification of ASF1B as a prognostic marker for liver cancer by meta-analysis and its immune value revealed by a comprehensive pan-cancer analysis of 33 human cancersrevealed by a comprehensive pan-cancer analysis of 33 human cancers","authors":"Yiyang Chen, Wanbang Zhou, Yiju Gong, Xi Ou","doi":"10.5114/pg.2023.124423","DOIUrl":"https://doi.org/10.5114/pg.2023.124423","url":null,"abstract":"Introduction As one of the most common malignant tumours, liver cancer is difficult to detect in the early stage, with strong metastasis and poor prognosis. Anti-silencing function protein 1 was originally discovered in yeast as a histone H3-H4 chaperone, and studies have shown that ASF1B may be a target for inhibiting the growth of hepatocellular carcinoma cells. Aim To evaluate the diagnostic and prognostic significance of ASF1B expression in human LIHC on the basis of TCGA data. Material and methods A meta-analysis revealed that high ASF1B expression was strongly associated with better overall survival. A comprehensive pan-cancer analysis of 33 human cancers revealed the immunotherapeutic value of ASF1B. Results In this study, we observed a significant upregulation of ASF1B expression in LIHC samples compared to non-cancer samples. Clinical analysis showed that high expression of ASF1B was associated with age, tumour status, and clinical stage. Survival analysis showed that patients with high ASF1B expression had worse overall survival and progression-free survival than patients with low ASF1B expression. The AUCs of the 1-year, 3-year, and 5-year survival-related ROC curves were 0.672, 0.590, and 0.591, respectively. Conclusions Our study shows that ASF1B may provide new ideas for the diagnosis and prognosis of liver cancer patients, as well as providing a new direction for the application of ASF1B in tumour immunotherapy.","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"6 1","pages":"249 - 265"},"PeriodicalIF":1.3,"publicationDate":"2023-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics of the endoscopic procedures performed in a hybrid tertiary-level hospital during the first year of the COVID-19 pandemic. COVID-19大流行第一年在三级混合医院进行的内窥镜手术的特点

IF 1.3

Przegla̜d Gastroenterologiczny Pub Date : 2023-01-01 DOI: 10.5114/pg.2022.118136

Héctor Adrián Díaz Hernández, José Elihú Cuevas Castillejos, Godolfino Miranda Zazueta, Adriana Fabiola Romano Munive, Francisco Valdovinos Andraca

{"title":"Characteristics of the endoscopic procedures performed in a hybrid tertiary-level hospital during the first year of the COVID-19 pandemic.","authors":"Héctor Adrián Díaz Hernández, José Elihú Cuevas Castillejos, Godolfino Miranda Zazueta, Adriana Fabiola Romano Munive, Francisco Valdovinos Andraca","doi":"10.5114/pg.2022.118136","DOIUrl":"https://doi.org/10.5114/pg.2022.118136","url":null,"abstract":"Introduction: The COVID-19 pandemic caused many changes in gastrointestinal endoscopy units.Aim: To describe the changes that occurred in a gastrointestinal endoscopy unit of a hybrid hospital during the COVID-19 pandemic.Material and methods: We performed a retrospective study of endoscopies performed in the first year of the COVID-19 pandemic. We collected and described the data of interest to the study, which is presented with numbers and percentages or measures of central tendency and dispersion as appropriate. Fisher's exact test or the χ2 test were used as appropriate.Results: A total of 507 procedures were performed. There was a 92.5% reduction in the performance of endoscopic procedures. In all, 77 (15%) procedures were performed on patients with COVID-19. The most frequent procedures were esophagogastroduodenoscopy (EGD), colonoscopy, and endoscopic retrograde cholangiopancreatography (ERCP). The main indications were gastrointestinal bleeding, placement of enteral accesses, and alterations in the biliary and pancreatic ducts. Of these, 37 (48%) were therapeutic. Patients with COVID-19 were more susceptible to the development of complications.Conclusions: During the first year of the COVID-19 pandemic, the number of endoscopic procedures performed decreased significantly. The procedures most often required were EGD, colonoscopy, and ERCP, mainly indicated by gastrointestinal bleeding, placement of enteral accesses, and alterations of the bile and pancreatic ducts.","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"18 2","pages":"198-203"},"PeriodicalIF":1.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dd/09/PG-18-47490.PMC10395057.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9935790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of deep learning in diagnosing colorectal cancer. 深度学习在癌症诊断中的作用。

IF 1.3

Przegla̜d Gastroenterologiczny Pub Date : 2023-01-01 Epub Date: 2023-07-17 DOI: 10.5114/pg.2023.129494

Dimitrios Bousis, Georgios-Ioannis Verras, Konstantinos Bouchagier, Andreas Antzoulas, Ioannis Panagiotopoulos, Anastasia Katinioti, Dimitrios Kehagias, Charalampos Kaplanis, Konstantinos Kotis, Christos-Nikolaos Anagnostopoulos, Francesk Mulita

引用次数: 4

Appleby technique: review of the state of the art 阿普尔比技术:对最新技术的回顾

IF 1.3

Przegla̜d Gastroenterologiczny Pub Date : 2023-01-01 DOI: 10.5114/pg.2023.129502

D. Coco, S. Leanza

引用次数: 0

Biological markers of disease activity in inflammatory bowel diseases. 炎症性肠病疾病活动性的生物学标志物。

IF 1.3

Przegla̜d Gastroenterologiczny Pub Date : 2023-01-01 DOI: 10.5114/pg.2023.129412

Edyta Szymanska, Sylwia Szymanska, Maciej Dadalski, Jaroslaw Kierkus

引用次数: 0

Type B aortic dissection atypically presenting as chronic abdominal pain. B型主动脉夹层非典型表现为慢性腹痛。

IF 1.3

Przegla̜d Gastroenterologiczny Pub Date : 2023-01-01 DOI: 10.5114/pg.2023.129417

Rafał Filip, Wiesław Guz

引用次数: 0

Splenic artery embolization for the treatment of pancreatic portal hypertension complicated by gastric variceal haemorrhage. 脾动脉栓塞治疗胰门脉高压合并胃静脉曲张出血。

IF 1.3

Przegla̜d Gastroenterologiczny Pub Date : 2023-01-01 DOI: 10.5114/pg.2022.121829

Min Ai, DaZhi Gao, GuangMing Lu, Jian Xu

引用次数: 0