Przegla̜d Gastroenterologiczny最新文献

{"title":"Should physicians prescribe probiotics alongside antibiotics? A practical perspective.","authors":"Wojciech Marlicz, Grażyna Rydzewska","doi":"10.5114/pg.2025.148588","DOIUrl":"10.5114/pg.2025.148588","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"20 1","pages":"1-4"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of early and long-term clinical outcomes in obstructed proximal and distal colon cancers undergoing emergent surgery.","authors":"Ulaş Aday, Abdulkadir Akbaş, Hikmet Özesmer, Hasan Akkoç","doi":"10.5114/pg.2024.145475","DOIUrl":"10.5114/pg.2024.145475","url":null,"abstract":"<p><strong>Introduction: </strong>Studies comparing proximal and distal colon tumours undergoing emergent surgery for obstruction are limited.</p><p><strong>Aim: </strong>The purpose of our study was to compare the clinical and oncological outcomes of patients with proximal and distal colon cancer, who underwent emergent surgery for obstruction.</p><p><strong>Material and methods: </strong>From January 2012 to June 2022, patients with colon cancer presenting with obstruction and undergoing emergent surgery were analysed. The 2 groups were defined as proximal and distal according to the tumour location with respect to the splenic flexure. Postoperative early and long-term clinical and oncological outcomes were analysed.</p><p><strong>Results: </strong>Of the 118 patients included in the study, there were 46 patients (38.9%) in the proximal group and 72 patients (61.1%) in the distal group. Single-session surgery including resection and anastomosis was performed on 31 (67.4%) and 29 (40.3%) patients in the proximal and distal groups, respectively (<i>p</i> = 0.007). The global mortality rate was 11%, and there was no difference between the groups. Five-year survival was similar in the proximal and distal groups, being 80.4% and 68.1%, respectively. In the analysis of patients who did not develop early mortality and underwent R0 resection, 3-year disease-free survival was 89.5% in the proximal group and 81.5% in the distal group; the difference was not significant (<i>p</i> = 0.165).</p><p><strong>Conclusions: </strong>Mortality is high in emergent surgeries for obstructed proximal and distal colon cancers. If curative resection is achieved, oncological results are good and tumour localisation does not affect survival.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"20 1","pages":"71-77"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Connection of vitamin D levels in blood serum with <i>Helicobacter pylori</i> infection in paediatric patients.","authors":"Kairat Rysbekov, Sagira Abdrakhmanova, Rashida Satybaeva, Dmitry Babenko, Zhanat Abdikadyr","doi":"10.5114/pg.2024.146213","DOIUrl":"10.5114/pg.2024.146213","url":null,"abstract":"<p><strong>Introduction: </strong><i>Helicobacter pylori</i> is a globally prevalent infection, particularly in developing countries, with significant implications for gastrointestinal health in children. Recent studies suggest a potential link between vitamin D and its metabolites in enhancing the effectiveness of <i>H. pylori</i> eradication therapies through their bactericidal properties.</p><p><strong>Aim: </strong>To investigate the correlation between the vitamin D levels and their influence on clinical management and treatment results of children patients, tested for <i>H. pylori</i>.</p><p><strong>Material and methods: </strong>The study was conducted on a cohort of 128 paediatric patients. They were divided into 2 groups, depending on whether positive (first group - A) or negative (second group - B) for <i>H. pylori</i>. To determine vitamin D levels, venous blood was taken from all participants from both groups. Group 1 included patients whose indexes were up to 10 ng/ml; Group 2 included patients whose indexes were from 10 ng/ml to 20 ng/ml; Group 3 levels were from 20 ng/ml to 30 ng/ml; and Group 4 indexes were over 30 ng/ml. The efficiency of the <i>H. pylori</i> eradication scheme in participants of these groups was evaluated.</p><p><strong>Results: </strong>The mean values in Group A were higher than those in Group B: 17.1 and 14.9, respectively, <i>p</i>-value 0.03. <i>Helicobacter pylori</i> prevalence was higher in participants with vitamin D levels below 30 ng/ml. As a result of the study, it was established that vitamin D levels below 30 ng/ml in blood serum could be a predisposing factor in the spread of <i>H. pylori</i> in paediatric patients. At the same time, different levels of deficiency below 30 ng/ml did not affect the frequency of <i>H. pylori</i> infection.</p><p><strong>Conclusions: </strong>The obtained data can be used in developing guidelines for clinical management of children patients who are primarily diagnosed with <i>H. pylori</i> and require eradication therapy.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"20 1","pages":"84-91"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New challenges in the management of inflammatory bowel disease: a case study.","authors":"Grazyna Piotrowicz, Agata Rudnik, Mariusz Śmigielski, Adam Piotrowicz, Magdalena Rzeszutek, Agnieszka Klufczyńska","doi":"10.5114/pg.2024.139242","DOIUrl":"10.5114/pg.2024.139242","url":null,"abstract":"","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"20 1","pages":"107-110"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying and evaluating factors related to feeding disorders in children using the path analysis method.","authors":"Amirhossein Hosseini, Saeedeh Sistani, Arsalan Sabooree, Maryam Mollaei, Seyed Ali Mofidi, Naghi Dara, Aliakbar Sayyari, Mahmoud Hajipour","doi":"10.5114/pg.2025.148478","DOIUrl":"10.5114/pg.2025.148478","url":null,"abstract":"<p><strong>Introduction: </strong>Pediatric feeding disorders (PFDs) refer to the impaired consumption of food that is inappropriate for a child's age group. Understanding the causes and influencing factors of PFDs is crucial for managing these disorders.</p><p><strong>Aim: </strong>This study aimed to analyze the factors associated with PFDs using the path analysis method.</p><p><strong>Material and methods: </strong>A cross-sectional study was conducted on 500 children aged 6 months to 18 years who visited gastroenterology and child nutrition clinics. Data were collected through interviews with mothers and physicians, and analyzed using the path analysis method. The model included latent variables such as feeding disorders and birth status, as well as observed variables such as socio-economic status, food group, feeding practices, destructive behaviors, sleep, and body mass index (BMI) <i>z-</i>score.</p><p><strong>Results: </strong>We conducted three path analyses. The socio-economic status (SES) directly and indirectly plays a role in feeding disorders in children; the total effect on feeding disorders was positive (β = 0.075). The direct effect of SES on the intake of food groups was positive (β = 0.190), on BMI <i>z-</i>score was positive (β = 0.100), and it was generally associated with a negative effect on feeding disorders (β = -0.05). The total effect of destructive behaviors on body mass was negative (β = 0.262) and on feeding disorders was positive (β = -0.041). Children who had regular sleep had significantly fewer feeding disorders (total effect: -0.369).</p><p><strong>Conclusions: </strong>Socio-economic status, destructive behaviors, sleep, and BMI were found to be factors influencing eating disorders in children.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"20 1","pages":"55-61"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structured exercise in patients with inflammatory bowel disease: a literature review.","authors":"Magdalena Achtenberg, Dorota Cibor, Małgorzata Zwolińska-Wcisło","doi":"10.5114/pg.2025.148473","DOIUrl":"10.5114/pg.2025.148473","url":null,"abstract":"<p><p>Many patients with inflammatory bowel disease (IBD) either do not respond or lose response to dedicated pharmacotherapy; therefore, physical exercise is gaining attention as a potential treatment adjunct. Recent research has highlighted the favorable relationship between physical activity and patient-reported outcomes. The reviewed studies suggest that structured exercise programs are safe and effective in the management of IBD. Yet the benefits of training trials need to be interpreted with caution due to the heterogeneity of the study methods and interventions, small sample sizes, and the absence of long-term follow-ups.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"20 1","pages":"36-40"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11966504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological rhythms of the gut and microbiota.","authors":"Albert Chodowiec, Mirosław Tarasewicz, Anna Łokić, Marcin Kazberuk, Anatol Panasiuk","doi":"10.5114/pg.2023.132437","DOIUrl":"https://doi.org/10.5114/pg.2023.132437","url":null,"abstract":"<p><p>Numerous physiological processes occurring in the digestive system are subject to circadian rhythms, which are regulated by the endogenous biological clock. The motor activity of the small intestine, large intestine, and rectum operates in a 24-hour system, with significant differences between day and night periods. It is primarily correlated with the time of meals, hormone secretion rhythms, and other activities undertaken by the organism. In recent years, numerous scientific reports have emerged about the fundamental role of circadian rhythms in the proper functioning of the gut microbiota. In addition, the microbiota and its metabolites also influence the host's daily cycles, which affects the overall state of their organism. The aim of this review is to outline the mechanisms of action and interactions between biological rhythms, gut motility, and the functioning of the gut microbiota.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 1","pages":"18-22"},"PeriodicalIF":1.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10985757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140860605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of left ventricular assist devices on 30-day readmission and outcomes in non-variceal upper gastrointestinal bleeding: a nationwide analysis.","authors":"Umer Farooq, Zahid Ijaz Tarar, Adnan Malik, Muhammad Kashif Amin, Mustafa Gandhi, Moosa Tarar, Faisal Kamal","doi":"10.5114/pg.2023.134394","DOIUrl":"https://doi.org/10.5114/pg.2023.134394","url":null,"abstract":"<p><strong>Introduction: </strong>Bleeding, especially non-variceal upper gastrointestinal bleeding (NVUGIB), remains the most common cause of readmission in left ventricular assist device (LVAD) patients. Any readmission after NVUGIB carries a worse prognosis.</p><p><strong>Aim: </strong>To compare readmission outcomes in NVUGIB patients with and without LVAD.</p><p><strong>Material and methods: </strong>We identified adult NVUGIB patients using the National Readmission Database 2018 employing International Classification of Diseases, Tenth Revision (ICD-10) codes. The patients were grouped based on LVAD history. Proportions were compared using the Fisher exact test, and multivariate Cox proportional regression analysis was used to compute adjusted <i>p</i>-values. We used Stata version 14.2 to perform analyses considering 2-sided <i>p</i> < 0.05 as statistically significant.</p><p><strong>Results: </strong>The analysis included 322,342 NVUGIB patients, 1403 had a history of LVAD (mean age 64.25 years). The 30-day all-cause readmission rate in NVUGIB with LVAD was higher (24.31% vs. 13.92%, <i>p</i> < 0.001). Gastrointestinal bleeding as a readmission cause was more prevalent in the LVAD group. In patients with LVAD, NVUGIB readmissions required more complex endoscopic procedures, either requiring intervention during endoscopy or enteroscopy. There was no difference in mortality in NVUGIB readmissions (1.51% vs. 4.49%, <i>p</i> = 0.36); however, the length and cost of stay were higher in the LVAD group. Additionally, we identified novel independent predictors of readmission from NVUGIB in patients with LVADs.</p><p><strong>Conclusions: </strong>Readmissions in NVUGIB patients after LVAD require complex haemostatic intervention and are associated with greater resource utilization. To reduce readmissions and associated healthcare costs, it is essential to identify high-risk patients.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 2","pages":"175-185"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11200072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SARS-CoV-2 vaccination in inflammatory bowel disease (IBD) patients - does treatment for IBD negatively affect SARS-CoV-2 antibodies? A single-centre, prospective study.","authors":"Katarzyna Karłowicz, Konrad Lewandowski, Edyta Tulewicz-Marti, Katarzyna Maciejewska, Adam Tworek, Beata Stępień-Wrochna, Martyna Głuszek-Osuch, Michał Łodyga, Grażyna Rydzewska","doi":"10.5114/pg.2023.130126","DOIUrl":"10.5114/pg.2023.130126","url":null,"abstract":"<p><strong>Introduction: </strong>Inflammatory bowel disease (IBD) patients use a wide variety of immunosuppressive drugs, including biologics, but their effect on SARS-CoV-2 vaccine antibody levels remains a mystery.</p><p><strong>Aim: </strong>We analysed whether the drugs used in the treatment of IBD patients could affect the concentration of SARS-CoV-2 antibodies.</p><p><strong>Material and methods: </strong>This is a prospective, single-centre evaluation of the persistence of SARS-CoV-2 antibodies after vaccination at various time points: every 2 months throughout the 6^th month after the first dose.</p><p><strong>Results: </strong>We included a total of 346 vaccinated IBD patients in the study. A negative correlation between antibody level and time from full vaccination was confirmed for the following types of therapy: infliximab (rho = -0.32, <i>p</i> < 0.001), adalimumab (rho = -0.35, <i>p</i> = 0.025), and vedolizumab (rho = -0.50, <i>p</i> < 0.001). In the case of other, long-term drug administration, a negative correlation between antibody level and time from full vaccination was confirmed for mesalazine (rho = -0.35, <i>p</i> < 0.001), budesonide (rho = -0.58, <i>p</i> = 0.004), systemic glucocorticoids (rho = -0.58, <i>p</i> < 0.001), and azathioprine (rho = -0.44, <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Due to the immunosuppressive and biological treatment, IBD patients are exposed to a shorter persistence of SARS-CoV-2 antibodies and require booster doses. The role of gastroenterologists in educating patients about the need to continue SARS-CoV-2 vaccination remains crucial.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"1 1","pages":"198-205"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11200064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of artificial intelligence and image processing in the diagnosis, treatment, and prognosis of liver cancer: a narrative-review.","authors":"Platon Dimopoulos, Admir Mulita, Andreas Antzoulas, Sylvain Bodard, Vasileios Leivaditis, Ioanna Akrida, Nikolaos Benetatos, Konstantinos Katsanos, Christos-Nikolaos Anagnostopoulos, Francesk Mulita","doi":"10.5114/pg.2024.143147","DOIUrl":"10.5114/pg.2024.143147","url":null,"abstract":"<p><p>Artificial intelligence (AI) and image processing are revolutionising the diagnosis and management of liver cancer. Recent advancements showcase AI's ability to analyse medical imaging data, like computed tomography scans and magnetic resonance imaging, accurately detecting and classifying liver cancer lesions for early intervention. Predictive models aid prognosis estimation and recurrence pattern identification, facilitating personalised treatment planning. Image processing techniques enhance data analysis by precise segmentation of liver structures, fusion of information from multiple modalities, and feature extraction for informed decision-making. Despite progress, challenges persist, including the need for standardised datasets and regulatory considerations.</p>","PeriodicalId":20719,"journal":{"name":"Przegla̜d Gastroenterologiczny","volume":"19 3","pages":"221-230"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}