Buletin Farmatera最新文献_第4页

PROFILE OF MICROORGANISMS CAUSING VAGINAL DISCHARGE IN REPRODUCTIVE WOMEN AT DR. PIRNGADI HOSPITAL IN MEDAN 棉兰Pirngadi医生医院生殖妇女阴道分泌物微生物概况

Buletin Farmatera Pub Date : 2020-02-18 DOI: 10.30596/bf.v5i1.3934

Iqrina Widya Zahara, I. D. Roesyanto, S. Amelia

{"title":"PROFILE OF MICROORGANISMS CAUSING VAGINAL DISCHARGE IN REPRODUCTIVE WOMEN AT DR. PIRNGADI HOSPITAL IN MEDAN","authors":"Iqrina Widya Zahara, I. D. Roesyanto, S. Amelia","doi":"10.30596/bf.v5i1.3934","DOIUrl":"https://doi.org/10.30596/bf.v5i1.3934","url":null,"abstract":"Leucorrhoea or Fluor albus or leukorrhea vaginal discharge is the discharge of fluid other than blood from the vaginal canal out of the ordinary, either smelling or not, and accompanied by local itching. There are two factors that cause leucorrhoea, namely endogenous factor such as abnormalities in the vagina and exogenous factor which are infection and non-infection. The aim of this study is to find the profile of microorganisms causing vaginal discharge in reproductive women. This is a descriptive study with cross-sectional method conducted at the Skin and Genital Polyclinic of the Sexually Transmitted Infectious Disease Division and the Obstetrics and Gynecology Clinic of Pirngadi Hospital, Medan. Populations that have met the inclusion and exclusion criterias were included in the study. Vaginal discharge samples will be sent to the microbiology laboratory and the parasitology laboratory of faculty medicine of University of North Sumatera to examine the gram staining, KOH staining, bacterial and fungal cultures and wet preparations for parasites. Out of a total of 50 people, the majority of the sample are in aged 31-40 years, with a history of high school education and working women. The most types of vaginal discharge are pathological (84%) and the most common cause of vaginal discharge is a fungal infection by Candida sp (90%) followed by bacterial infection by Staphylococcus aureus (64.8%) and Klebsiella (20.3%)","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126246251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

ANTIHIPERGLICEMIC THERAPY COMPLIANCE WITH HbA1C LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS AMONG PEKANBARU PROLANIS PARTICIPANTS 北坎巴鲁PROLANIS参与者中2型糖尿病患者的HbA1C水平对抗高血糖治疗的依从性

Buletin Farmatera Pub Date : 2020-02-18 DOI: 10.30596/bf.v5i1.4203

D. P. Nugraha, E. Asni, Ligat Pribadi Sembiring

{"title":"ANTIHIPERGLICEMIC THERAPY COMPLIANCE WITH HbA1C LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS AMONG PEKANBARU PROLANIS PARTICIPANTS","authors":"D. P. Nugraha, E. Asni, Ligat Pribadi Sembiring","doi":"10.30596/bf.v5i1.4203","DOIUrl":"https://doi.org/10.30596/bf.v5i1.4203","url":null,"abstract":"One of the pillars in the management of Type 2 Diabetes Mellitus (DM) is pharmacotherapy, i.e. the use of antihyperglycemic drugs. Success in DM management is influenced by patient compliance to the pharmacotherapy given. One indicator of controlling Type 2 DM is HbA1c levels. This study aimed to analyze the relationship between antihyperglycemic therapy compliance and the HbA1c levels in Type 2 DM patients in the Chronic Disease Management Program in Pekanbaru. Method. This was a cross-sectional study. Samples were taken by consecutive sampling method. Laboratory examination was carried out to obtain HbA1c levels, the value of which was categorized controlled if <7%. The compliance with the use of antihyperglycemic drugs was assessed using Medication Possession Ratio (MPR). Patients were considered compliant if they had an MPR of ≥80%. Data were analyzed using the Fisher Exact test. Results . Most of the 48 patients had uncontrolled HbA1c levels (87,5%). The level of non-compliant patients was also very high (91,7%). This study showed a significant relationship between pharmacotherapy compliance and HbA1c levels ( p <0.05). Discussion . There was a relationship between pharmacotherapy compliance and the level of HbA1c in Type 2 DM patients. Physicians should pay more attention to patients with low compliance as it may increase the risk to a high HbA1c level","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132842271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE EFFECTIVITY OF THE ETHANOL EXTRACT OF EGGPLANT (SOLANUM MELONGENA L.) PEELS AS ANTIMALARIAL TO MONOCYTE IN MICE (MUS MUSCULUS) INDUCED BY PLASMODIUM BERGHEI 茄子醇提物的药效研究。果皮对伯氏疟原虫诱导小鼠单核细胞的抗疟作用

Buletin Farmatera Pub Date : 2019-09-30 DOI: 10.30596/BF.V4I3.3119

Ari Widiyantoro

{"title":"THE EFFECTIVITY OF THE ETHANOL EXTRACT OF EGGPLANT (SOLANUM MELONGENA L.) PEELS AS ANTIMALARIAL TO MONOCYTE IN MICE (MUS MUSCULUS) INDUCED BY PLASMODIUM BERGHEI","authors":"Ari Widiyantoro","doi":"10.30596/BF.V4I3.3119","DOIUrl":"https://doi.org/10.30596/BF.V4I3.3119","url":null,"abstract":"Malaria is a disease caused by Plasmodium that is transmitted to humans by the bite of the female Anopheles mosquito. Malaria can be treated with antimalarial drugs such as chloroquine and artemisinin, but in some endemic areas, it is reported that parasitic resistance to chloroquine was reported so that malaria eradication becomes increasingly difficult. The occurrence of this resistance causes the need for new antimalarial findings. Eggplant (Solanum melongena L.) has many secondary metabolites, one of which is solanidine which is toxic to bacteria, fungi, viruses, and protozoa. Eggplant peel was extracted by maceration method using 70% ethanol. The analysis of secondary metabolites from the ethanol extract of eggplant peels used tube test and thin-layer chromatography. The level of parasitemia and the number of monocytes were calculated from blood smear of mice (Mus musculus) which were treated with extracts at a dose of 0.075 mg/20 g of body weight; 0.15 mg/20 of body weight; and 0.3 mg/20 g of body weight. 3.744 mg/20 g of body weight Dihydroartemisinin-Piperaquine (DHP) was used as positive control and distilled water was used as the negative control. Ethanol extract of the eggplant peels contains groups of alkaloids, flavonoids, terpenoids, steroids, phenolic, and saponins. 0.075 mg/20 g body weight of ethanol extract of the eggplant peels effectively reduces parasitemia and 0.3 mg/20 g body weight of ethanol extract of the eggplant peels effectively increases the number of monocytes in mice. There is no correlation between an increase in the number of monocytes and a decrease in the level of parasitemia. Keywords: antimalarial, eggplant, monocyte, Plasmodium berghei, Solanum melongena L.","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134197768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PREDICTORS OF IN-HOSPITAL LENGTH OF STAY IN NSTEMI PATIENTS 非传染性疾病患者住院时间的预测因素

Buletin Farmatera Pub Date : 2019-09-30 DOI: 10.30596/bf.v4i3.2156

A. Handayani, A. Sitepu, F. Habib

{"title":"PREDICTORS OF IN-HOSPITAL LENGTH OF STAY IN NSTEMI PATIENTS","authors":"A. Handayani, A. Sitepu, F. Habib","doi":"10.30596/bf.v4i3.2156","DOIUrl":"https://doi.org/10.30596/bf.v4i3.2156","url":null,"abstract":"As our population grows older, the rate of NSTEMI patients is rising. Risk stratification is an important process for patients with Non-ST Elevation Myocardial Infarction (NSTEMI). Global Registry of Acute Coronary Events (GRACE) scores in the best to predict mortality and myocardial infarction in NSTEMI Patients. On the other hand, NSTEMI Patients trends to be older with more co-morbidity. In this scenario, we need to predict the length of stay as it correlates with the patient's prognostic and cost. This study aims to analyze factors influencing the in-hospital length of stay in survivor NSTEMI Patients in four different hospitals (Adam Malik Medan National General Hospital, Pirngadi Medan General Hospital, Grandmed Lubuk Pakam General Hospital, and Aceh Tamiang Public General Hospital). This was an observational study with prospective design conducted on 44 patients in four different hospitals from March to May 2017. We only included the patients that discharged alive from the. hospital Statistical analysis was performed to assess the routine clinical and laboratory variables relations with the length of stay. Prolong length of stay was defined as more than 5 days. As mentioned in the previous study, older age, heart failure will prolong the length of stay. The limitations of this study were we didn't analyze the effect of revascularization, the co-morbidities, and the method of patient’s payment. We should use GRACE and TIMI risk score routinely, optimizing therapy for heart failure and giving special attention to elderly patients in NSTEMI Patients. Keywords: NSTEMI, GRACE, Length of Stay","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124623003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE IMPACT OF LONGER WORKING TO MERCURY LEVEL (HG) IN BLOOD OF THOSE TRADITIONAL GOLD MINERS AT DESA PANTON LUAS KABUPATEN ACEH SELATAN 长期工作对德萨潘顿luas kabupaten aceh selatan传统金矿工人血液中汞含量的影响

Buletin Farmatera Pub Date : 2019-09-30 DOI: 10.30596/bf.v4i3.3031

Syafruddin Din

引用次数: 0

THE DIFFERENCE BETWEEN THE EFFECTS OF CONTINUOUS RUNNING AND INTERVAL RUNNING TRAINING METHODS ON MAXIMUM OXYGEN VOLUME (O2) OF FOOTBALL ATHLETES AT EDUCATION CENTERS AND STUDENT TRAINING (PPLP) ACEH PROVINCE 亚齐省教育中心和学生训练中心(pplp)足球运动员连续跑和间歇跑训练方式对最大氧量(o2)影响的差异

Buletin Farmatera Pub Date : 2019-09-30 DOI: 10.30596/bf.v4i3.3451

Amirul Hadi

{"title":"THE DIFFERENCE BETWEEN THE EFFECTS OF CONTINUOUS RUNNING AND INTERVAL RUNNING TRAINING METHODS ON MAXIMUM OXYGEN VOLUME (O2) OF FOOTBALL ATHLETES AT EDUCATION CENTERS AND STUDENT TRAINING (PPLP) ACEH PROVINCE","authors":"Amirul Hadi","doi":"10.30596/bf.v4i3.3451","DOIUrl":"https://doi.org/10.30596/bf.v4i3.3451","url":null,"abstract":"The increase in aerobic exercise is influenced by cardiovascular performance, so to improve aerobic exercise it is necessary to increase the VO 2 Max value. The purpose of this study is to prove the differences in the effect of continuous running and interval running exercises on VO 2 Max in soccer athletes in PPLP Aceh Province. This study used analytic experimental with pre-test and post-test design. The study was conducted at the Harapan Bangsa Stadium in Banda City with a sample of 52 soccer athletes. Data analysis using Independent Sample T-Test. The result is there was an overall difference between continuous running practice and interval running for VO 2 max PPLP soccer athletes in Aceh Province. The average VO 2 max with the continuous running method exercise is 61.9 better than the running interval is 54.9. Sig value (2-tailed) VO 2 max data is 0.001 This means that there was a difference between continuous running and interval running exercises. From these results, it can be concluded that to improve the VO 2 max of a professional soccer athlete, training with the continuous running method is recommended compared to the interval running training method. Keywords: Continuous running, Interval running, and VO2 Max","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122622437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

EFFECTIVENESS OF PREEMPTIVE ANALGESIA IBUPROFEN 10 MG / KGBB PER ORAL FOR POSTOPERATIVE PAIN MANAGEMENT IN CHILDREN UNDERGOING MASS CIRCUMCISION 预防性镇痛布洛芬10mg / KGBB /次口服对包皮环切术后儿童疼痛管理的有效性

Buletin Farmatera Pub Date : 2019-09-30 DOI: 10.30596/BF.V4I3.2565

M. Chalil

{"title":"EFFECTIVENESS OF PREEMPTIVE ANALGESIA IBUPROFEN 10 MG / KGBB PER ORAL FOR POSTOPERATIVE PAIN MANAGEMENT IN CHILDREN UNDERGOING MASS CIRCUMCISION","authors":"M. Chalil","doi":"10.30596/BF.V4I3.2565","DOIUrl":"https://doi.org/10.30596/BF.V4I3.2565","url":null,"abstract":"Management of post-mass circumcision pain is often overlooked and not optimal because the administration of analgesia will be given when circumcision is complete. This study aims to determine the effectiveness of oral 10 mg / KGBB ibuprofen as preemptive analgesia for the management of post mass circumcision pain. After obtaining permission from the ethics commission of the FK UMSU clinical research, a prospective double-blind randomized controlled clinical trial was conducted on 28 children in consecutive sampling who met the inclusion and exclusion criteria. Samples were randomized into 2 groups, A was given ibuprofen 10 mg/kg BW orally 1 hour before incision and B was given ibuprofen 10 mg/kg BW orally at the time immediately after the circumcision was completed. Pain scale measurements were performed using FPR-S (Faces Pain Scale-Revised) at the 1st, 2nd, 4th, 6th and 8th postoperative hours. Monitoring of the 1st to 4th hours is carried out at the location of the activity, while the 6th to 8th hours are carried out by telephone. There was a significant decrease in pain scale at the 1st hour (p = 0.031) in group A. At the second to eighth-hour monitoring, the effectiveness of the two methods was the same. In conclusion, the method of preemptive analgesia is effective for the management of post-mass circumcision pain. Keywords: preemptive analgesia, post-circumcision pain","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"447 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133781880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ASSOCIATION OF PPARΑ INTRON 7 G/C (RS4253778) POLYMORPHISMS WITH MUSCULAR ENDURANCE AMONG SOCCER SCHOOL STUDENTS IN MEDAN pparΑ内含子7g / c (rs4253778)多态性与中部足球学校学生肌肉耐力的关系

Buletin Farmatera Pub Date : 2019-09-30 DOI: 10.30596/bf.v4i3.3083

Roy Wilson Sihaloho, Y. Siregar, M. Savira

{"title":"ASSOCIATION OF PPARΑ INTRON 7 G/C (RS4253778) POLYMORPHISMS WITH MUSCULAR ENDURANCE AMONG SOCCER SCHOOL STUDENTS IN MEDAN","authors":"Roy Wilson Sihaloho, Y. Siregar, M. Savira","doi":"10.30596/bf.v4i3.3083","DOIUrl":"https://doi.org/10.30596/bf.v4i3.3083","url":null,"abstract":"Peroxisome proliferator-activated receptor alpha (PPARα) is the transcription factor gene that regulates lipid metabolism and glucose homeostasis of energy within the mitochondria. PPARα gene Intron 7 variation is associated with the phenotype of human performance. Homozygous GG is more often found among athletes concerning muscular endurance. This study aims to investigate the association of PPARα polymorphism with muscular endurance. Samples from buccal cells were collected from 77 boys (aged 11-16 years). PPARα Intron 7 polymorphism was examined using PCR-RFLP with restriction enzyme TaqI. Meanwhile, the Curl-Up test has been performed to determine the muscular endurance of the subjects. The relationship between PPARα Intron 7 polymorphism with muscular endurance was assessed by using Fisher’s Exact test. The study found the genotype GG and GC of 97.4% and 2.6%, respectively. Muscular endurance was shown among categories of poor (66.2%) and fair (15.6%). Statistical analysis established no association between PPARα polymorphism with muscular endurance (p = 0,564). Keywords: PPARα polymorphisms, muscular endurance, Curl-Up test","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121822735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RISK FACTORS ANALYSIS OF HEARING DISORDERS DUE TO NOISE ON MACHINERY WORKERS AT UNIVERSAL STEEL FACTORY 万能钢铁厂机械工人噪声致听力障碍危险因素分析

Buletin Farmatera Pub Date : 2019-06-30 DOI: 10.30596/BF.V4I2.2989

Elvira Kesuma, M. E. S. Nasution

引用次数: 0

ASSOCIATION OF DISEASE HISTORY WITH RHEGMATOGENOUS RETINAL DETACHMENT AMONG PATIENTS IN DEPARTMENT OF OPHTHALMOLOGY AT DR. MOHAMMAD HOESIN ACADEMIC GENERAL HOSPITAL PALEMBANG 巨港学术综合医院Mohammad hoesin博士眼科患者的疾病史与孔源性视网膜脱离的关系

Buletin Farmatera Pub Date : 2019-06-30 DOI: 10.30596/BF.V4I2.2988

Ramzi Amin, Indri Seta Septadina, D. Putri

{"title":"ASSOCIATION OF DISEASE HISTORY WITH RHEGMATOGENOUS RETINAL DETACHMENT AMONG PATIENTS IN DEPARTMENT OF OPHTHALMOLOGY AT DR. MOHAMMAD HOESIN ACADEMIC GENERAL HOSPITAL PALEMBANG","authors":"Ramzi Amin, Indri Seta Septadina, D. Putri","doi":"10.30596/BF.V4I2.2988","DOIUrl":"https://doi.org/10.30596/BF.V4I2.2988","url":null,"abstract":"Abstract. Retinal detachment is the detachment of neuroretina from pigmented retinal epithelial layer which supplying it. Retinal detachment which is untreated could lead into permanent visual impairment. According to its etiology, retinal detachment can be classified into rhegmatogenous and non-rhegmatogenous, where rhegmatogenous cause is more common that the other. Rhegmatogenous retinal detachment is associated with many previous disease history. Research was to determine the association between previous disease history and rhegmatogenous retinal detachment in the patient in Department of Ophthalmology at Dr. Mohammad Hoesin Academic General Hospital, Palembang. This was an analytical observational study using cross sectional design. Population of study was patients which had been diagnosed as having retinal detachment at the study site. One hundred and fifty-five of 267 patients were taken as study sample by using consecutive sampling technique. Data was obtained from patients’ medical records from 1 January 2015 to 31 August 2018. Analysis of association showed the following results: previous cataract surgery (p=0,038; PR=1,309), high degree myopia (p=0,014; PR=1,400) and trauma history (p=0,036; PR=1,350). There were significant associations between previous cataract surgery, high degree myopia and trauma history with rhegmatogenous retinal detachment. Keywords: Previous cataract surgery, myopia, trauma, rhegmatogenous retinal detachment.","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121202471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0