Buletin Farmatera最新文献

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ApaI Vitamin D Receptor Gene Polymorphisms in Psoriasis 银屑病ApaI维生素D受体基因多态性
Buletin Farmatera Pub Date : 2020-10-20 DOI: 10.30596/BF.V6I1.6528
Widyaningsih Oentari, I. D. Roesyanto-Mahadi, Y. Siregar
{"title":"ApaI Vitamin D Receptor Gene Polymorphisms in Psoriasis","authors":"Widyaningsih Oentari, I. D. Roesyanto-Mahadi, Y. Siregar","doi":"10.30596/BF.V6I1.6528","DOIUrl":"https://doi.org/10.30596/BF.V6I1.6528","url":null,"abstract":"Psoriasis is a chronic autoimmune skin disorder that is an autoimmune disease and still considers a global problem. This condition is suspected to be contributed by genetic and environmental factors. Several studies have shown an association between vitamin D gene receptor polymorphisms and the risk of psoriasis. This study was an observational study, which involved 64 research subjects, who were psoriasis patients. Each subject was interviewed and went through physical examination, also Polymerase Chain Reaction - Restriction Fragment Length Polymorphism (PCR-RFLP) examination to determine ApaI (rs7975232) vitamin D receptor gene polymorphism. After the tabulation of the data, we found that the age of psoriasis onset in this study was 21 to 40 years old with an average of 34.40 ± 14.98 years old. The majority of our subjects ApaI VDR gene polymorphism genotype was aa (53.1%). This is consistent with the results of several studies conducted in Asia.","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130676081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bacteriology Test to Detect Coliform Bacteria in Beverages Sold at University Cafeteria in Medan 棉兰大学食堂售饮料中大肠菌群的细菌学检测
Buletin Farmatera Pub Date : 2020-10-20 DOI: 10.30596/BF.V5I3.3437.G4647
A. Simaremare
{"title":"Bacteriology Test to Detect Coliform Bacteria in Beverages Sold at University Cafeteria in Medan","authors":"A. Simaremare","doi":"10.30596/BF.V5I3.3437.G4647","DOIUrl":"https://doi.org/10.30596/BF.V5I3.3437.G4647","url":null,"abstract":"T The World Health Organization standard for clean and safe water is that 95% of the water samples examined do not contain coliform organisms per 100 mL. Contaminated beverages will lead to digestive tract diseases. Food poisoning cases come from contaminated can be sourced from school canteens, street vendors factories, households, family parties, and even hotels. One of the most frequent and sensitive laboratory tests to detect microorganisms contamination in water is a bacteriological examination. This research aimed to determine the microbiological quality of beverages sold in the university canteens in Medan. The microbiological examination is carried out by the Most Probable Number (MPN) method that consists of two stages, presumptive and confirmation test. From 15 samples of beverages tested, the percentage of samples contaminated with coliform bacteria was 100%, based on WHO criteria were low-risk category by 1 sample (6.7%), intermediate-risk by 5 samples (33.3%), and high-risk category by 9 samples (60%). Therefore, beverages sold in the canteen did not meet the condition for appropriateness to be consumed because of contamination by coliform bacteria.","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"113 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115499710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Management of Foreign Body of Peanuts in the Trachea in Children 儿童气管内花生异物的处理
Buletin Farmatera Pub Date : 2020-10-20 DOI: 10.30596/BF.V5I3.4261
J. Tobing
{"title":"Management of Foreign Body of Peanuts in the Trachea in Children","authors":"J. Tobing","doi":"10.30596/BF.V5I3.4261","DOIUrl":"https://doi.org/10.30596/BF.V5I3.4261","url":null,"abstract":"Foreign body is an object that enters an organ that comes from outside the body or from inside the body that does not normally exist. One of the objects in the respiratory tract can occur in the trachea and occur in many children. Case report: a girl, 1 year 11 months of age with complaints of shortness of breath since 1 day before, had tachypnea, indirect laryngoscopy: multiple secretions, difficulty speaking vocal cords, inspiratory-expiratory stridor (+), suprasternal, epigastric and intercostal ( +). Bronchoscopy: white round foreign body (impression: peanut) covering> 50% of the tracheal lumen over the carina, mucosal edema, and hyperemia. A bronchoscopy was administered as a diagnostic and therapeutic role","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115788803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IMAGING OF MENINGIOMA 脑膜瘤影像
Buletin Farmatera Pub Date : 2020-10-20 DOI: 10.30596/BF.V5I3.3805.G4648
Duma Ratna Sari Nasution, Ahmad Brata Rosa, Robert Sinurat, S. B. Hutagalung
{"title":"IMAGING OF MENINGIOMA","authors":"Duma Ratna Sari Nasution, Ahmad Brata Rosa, Robert Sinurat, S. B. Hutagalung","doi":"10.30596/BF.V5I3.3805.G4648","DOIUrl":"https://doi.org/10.30596/BF.V5I3.3805.G4648","url":null,"abstract":"Meningioma is one of the tumor in the brains that is extra-axial, which means it is not originated from  the brain cell. We report a case of a 60-year-old female, that was admitted to the emergency room (ER) of a secondary referral hospital, due to sudden weakness of upper and lower right extremities since 2 days prior. She had been experiencing a feeling of fullness in the left frontal head since the previous 3 months, along with some headache. She admitted to have had diabetes for the last 2 years. She also reported family history of brain tumor. Neurosurgeon has diagnosed the tumor as a meningioma with differential diagnose a metastatic tumor. A non contrast CT scan has found a meningioma. After being diagnosed, the patient underwent a craniotomy to remove the tumor. The histopathology finding confirmed the diagnosis of meningioma (WHO Grade I). Meningiomas are mostly hyperattenuating to surrounding brain parenchyma, while roughly one fourth are isodense. Overt calcification as in this case is usually seen in psammomatous and meningothelial. Well collaboration between clinician, radiologist, and histopathologist is the key to ensure patient’s recovery and safety","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115665421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Breastfeeding and Onset of Atopic Dermatitis in Children Patient: a Cross Sectional Study 母乳喂养与儿童特应性皮炎发病的作用:一项横断面研究
Buletin Farmatera Pub Date : 2020-06-19 DOI: 10.30596/bf.v5i2.3769
Arridha Hutami Putri, S. Purnama, I. D. Roesyanto
{"title":"Role of Breastfeeding and Onset of Atopic Dermatitis in Children Patient: a Cross Sectional Study","authors":"Arridha Hutami Putri, S. Purnama, I. D. Roesyanto","doi":"10.30596/bf.v5i2.3769","DOIUrl":"https://doi.org/10.30596/bf.v5i2.3769","url":null,"abstract":"Abstract: Atopic dermatitis (AD) is a multifactorial disease belongs to the \"burden disease\" in childhood. It needs to be prevented to reach their optimal growth. Exclusive breastfeeding given during the first six months of life provides nutritional benefits and is thought to protect children from allergic or infectious diseases, such as AD. This study aims to determine the relationship between breastfeeding and onset of atopic dermatitis. This was an observational analytic study using cross-sectional method. Samples were taken consecutively at the Dermatovenereology Polyclinic of referral hospital and Puskesmas in Medan. This study included all pediatric patients aged 6 months to <18 years diagnosed with AD and were interviewed with informed consent. Children who didn’t get breastmilk were excluded. There result was a significant relationship between breastfeeding (exclusively to partially) and AD onset. There was no relationship between breastfeeding (exclusively to prelacteally) and AD onset. Polyunsaturated fatty acids, sIgA, and TGF-β2 in the breast milk of mothers with atopy is lower than mothers without atopy. Breastfeeding exclusively has a protective effect on AD. Further research is needed to analyzes various factors by comparing genetic predisposition.","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129097143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resistance Test of Aedes aegypti Mosquito Larvae Against Organophosphate Insecticides at Medan Selayang 棉兰寺阳地区埃及伊蚊幼虫对有机磷杀虫剂抗性试验
Buletin Farmatera Pub Date : 2020-06-19 DOI: 10.30596/bf.v5i2.2791
Z. Lubis, Nurfadly Nurfadly
{"title":"Resistance Test of Aedes aegypti Mosquito Larvae Against Organophosphate Insecticides at Medan Selayang","authors":"Z. Lubis, Nurfadly Nurfadly","doi":"10.30596/bf.v5i2.2791","DOIUrl":"https://doi.org/10.30596/bf.v5i2.2791","url":null,"abstract":"Aedes aegypti is the main vector in several diseases such as Dengue Hemorrhagic Fever (DHF).Various types of efforts to control Aedes aegypti were carried out to terminate the transmission chain by spraying (organizing) the organophosphate insecticide. The use of irrational insecticides causes an increase in esterase enzymes, giving rise to the resistance of Aedes aegypti to insecticides. The purpose of this study is to determine the resistance status of Aedes aegypti larvae to organophosphate insecticides in Medan Selayang. The type of research used in this study is descriptive research with cross-sectional methods, using 276 larvae of Aedes aegypti. The results of this study are mosquito larvae that are susceptible (sensitive) to organophosphate insecticides by 66.3%, while mosquito larvae that are tolerant (moderate resistance) of organophosphate insecticides are 33.7% and resistant (high resistance) mosquito larvae were not found. There is 33.7% of Aedes aegypti larvae are tolerant (moderate resistance) to organophosphate insecticides and resistant (high resistance) mosquito larvae were not found.","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"190 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133027447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Overview of The Incidence of Hyperprolactinemia Side Effects in Schizophrenia Patients With Antipsychotic Therapy 精神分裂症患者抗精神病药物治疗中高催乳素血症副作用的发生率综述
Buletin Farmatera Pub Date : 2020-06-19 DOI: 10.30596/bf.v5i2.3761
Vivinia Ra Putri, D. Hasni, Nadia Purnama Dewi, Mutiara Anissa
{"title":"Overview of The Incidence of Hyperprolactinemia Side Effects in Schizophrenia Patients With Antipsychotic Therapy","authors":"Vivinia Ra Putri, D. Hasni, Nadia Purnama Dewi, Mutiara Anissa","doi":"10.30596/bf.v5i2.3761","DOIUrl":"https://doi.org/10.30596/bf.v5i2.3761","url":null,"abstract":"Antipsychotic-induced hyperprolactinemia disorder affects the morbidity and quality of life of the patient, and can lower the patient's adherence to taking antipsychotics, thereby lowering the therapeutic success rate. This study aims to figure out the incidence of hyperprolactinemia side effects in schizophrenia patients receiving antipsychotic therapy. This descriptive research was conducted at HB Saanin Psychiatric Hospital  Padang in January-June 2018. The population in this study is all schizophrenia patients in the HB. Saanin Psychiatric Hospital Padang Year 2018 and involved participants as many as 100 people recruited in consecutive sampling. Data were analyzed using a descriptive statistical method. The results showed that more than half of the patients were 59 people (59.0%) hyperprolactinemia. Patients with gynecomastia amounted to 16 people (16%). Patients with galactorrhea amounted to 3 people (3%). Patients with sexual dysfunction amounted to 19 people (19%). Male patients amounted to 60 people, 21 people (35%) The sexual dysfunction of female patients amounted to 40 people, 26 people (65%) Menstrual cycle changes. More than half of the Schizophrenia patients receiving antipsychotic therapy in this study suffer symptoms of hyperprolactinemia in the manifestation of galactorrhea, gynecomastia, menstrual disorders, and sexual dysfunction.","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116135310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Corn Silk (Stigma Maydis) Against Blood Glucose Levels of Type 2 Diabetes Mellitus Patients 玉米丝对2型糖尿病患者血糖水平的影响
Buletin Farmatera Pub Date : 2020-06-19 DOI: 10.30596/bf.v5i2.3989
Laurencia Alimin
{"title":"Effects of Corn Silk (Stigma Maydis) Against Blood Glucose Levels of Type 2 Diabetes Mellitus Patients","authors":"Laurencia Alimin","doi":"10.30596/bf.v5i2.3989","DOIUrl":"https://doi.org/10.30596/bf.v5i2.3989","url":null,"abstract":"According to WHO, in 2017 there are an estimated 425 million sufferers of diabetes mellitus. Indonesia is placed in the seventh rank in the world in 2015, with an estimated 10 million sufferers. To reduce the prevalence of type 2 diabetes mellitus, improvements need to be made, such as lifestyle modification and treatment. Most anti-diabetic drugs have high side effects. Corn silk is one of the natural ingredients that contain flavonoids, which can reduce blood fat levels. The dose of corn silk of 500 mg/kg BW is the best substance against diabetic rats from excessive weight loss. Therefore, corn silk can be calculated to have an anti-diabetic effect by using lipids, eliminating free radicals, and increasing antioxidant capacity.","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114643721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Difference of Effectivity Between Nutmeg Seed Extract (Myristica Fragrans Houtt) and Diazepam Based on Sleep Induction Time on Swiss Webster Mice 肉豆蔻籽提取物与地西泮对小鼠睡眠诱导时间的影响
Buletin Farmatera Pub Date : 2020-06-19 DOI: 10.30596/bf.v5i2.2877
A. Nasution, Debby Mirani Lubis Lubis
{"title":"The Difference of Effectivity Between Nutmeg Seed Extract (Myristica Fragrans Houtt) and Diazepam Based on Sleep Induction Time on Swiss Webster Mice","authors":"A. Nasution, Debby Mirani Lubis Lubis","doi":"10.30596/bf.v5i2.2877","DOIUrl":"https://doi.org/10.30596/bf.v5i2.2877","url":null,"abstract":"According to the National Sleep Foundation in America, more than one third (36%) of young adults aged 18-29 years reported having difficulty getting up early (compared to 20% at 30-64 years old and 9% over 65 years). The National Sleep Foundation also states that in Indonesia the prevalence of insomnia sufferers reaches 70% at least once a week and 30 million people have difficulty sleeping every night. This study is an experimental study with a post-test only control group design. The samples used were 27 male Swiss webster mice which were divided into three groups. The treatment group was given nutmeg seed extract at a dose of 7.5 mg / kgBW; the positive control group was given diazepam, and the negative control group was given aquabidest. The results showed the difference in the average value of sleep induction time in the treatment group was 2.97 minutes, positive control group 5.06 minutes, and negative control group 8.43 minutes with p = 0.00. Conclusion: There is a significant difference between the effectiveness of nutmeg seed extract 7.5 mg / kgBW with diazepam based on the time of sleep induction in Swiss webster male mice.","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125705898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Relationship Between Body Mass Index and Urinary Creatinine in Adolescent Girls 青春期少女体重指数与尿肌酐的关系
Buletin Farmatera Pub Date : 2020-06-19 DOI: 10.30596/bf.v5i2.3325
Nita Andriani Lubis, Geminsah Putra H Siregar, M. Ginting
{"title":"The Relationship Between Body Mass Index and Urinary Creatinine in Adolescent Girls","authors":"Nita Andriani Lubis, Geminsah Putra H Siregar, M. Ginting","doi":"10.30596/bf.v5i2.3325","DOIUrl":"https://doi.org/10.30596/bf.v5i2.3325","url":null,"abstract":"Adolscent girls phase (12-21 years) is a very important individual development segment, beginning with the maturation of physical and reproductive organs that characterize women of childbearing age. Body mass index (BMI) is one of indicator used to see women of childbearing age status related to pregnancy. Kidney damage causes an increase in urinary creatinine but high urinary creatinine does not necessarily indicate kidney damage. Our objective is to determine the relationship between BMI and urine creatinine  in adolscent girls in several Medan health schools. We performed an observasional study with cross sectional design of 56 participants   19-21 old girls. 24 hours urine creatinine concentration was measured using jaffe reaction method. The highest average BMI value (21.10 kg/m 2 is the normal category (75%), mean urine creatinine concentration (1263,86 mg/24 hour) is also normal category. Data analysis with spearman correlation between BMI and 24-hour urine creatinine level was not statistically different (p = 0.140). High BMI values tend to have high 24-hour urine creatinine levels too, but statistically there was no significant relationship between 24-hour urine creatinine levels and BMI values in this study.","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128762202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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