Chinese medicine and natural products最新文献

{"title":"The Mechanism of Action of Qihuang Jiangtang Capsule in the Treatment of Type 2 Diabetes Based on Network Pharmacology and Molecular Docking Technology","authors":"Mengmeng Ji, Ya-Nan Yu, Jiarui Wu, Jun Liu, Yanhua Jiang, Zhiwei Jing","doi":"10.1055/s-0042-1757460","DOIUrl":"https://doi.org/10.1055/s-0042-1757460","url":null,"abstract":"\u0000 Objective Our objective was to investigate the potential mechanism of action of Qihuang Jiangtang capsule (QHJTC) in the treatment of type 2 diabetes mellitus (T2DM) through network pharmacology and molecular docking.\u0000 Methods The active components of materia medica in the formula of QHJTC were searched on the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform and Encyclopedia of Traditional Chinese Medicine. The targets related to the active components were obtained via PubChem database. The targets related to T2DM were retrieved through the GeneCards database. The targets corresponding to the active components and diabetes mellitus were uploaded to the Venn diagrams website to get the Venn diagram, and the intersecting targets were the potential targets of QHJTC in treating T2DM. The active components and potential targets were imported into Cytoscape 3.7.2 software to construct the active component–potential target network, and the key compounds and targets were screened by the Network Analyzer module in the Tools module. The potential targets were imported into the STRING database to obtain the interaction relationships, so as to analyze and construct the protein–protein interaction (PPI) network by Cytoscape 3.7.2 software. The intersecting targets were introduced into Metascape for gene ontology (GO) functional enrichment analysis and Kyoto encyclopedia of genes and genomes (KEGG) pathway enrichment analysis. The top 20 signaling pathways obtained by the KEGG pathway enrichment analysis and the related targets and the corresponding targets were analyzed by using Cytoscape 3.7.2 software to construct the “active component–important target-key pathway network ” for the intervention of T2DM with QHJTC. The molecular docking of active components and core targets was performed with AutoDock software.\u0000 Results A total of 237 active components and 281 related targets were obtained from QHJTC, as well as 1 362 T2DM targets and 155 potential targets of QHJTC in treating T2DM. There were 32 key components and 49 key targets identified by the active component–potential target network topology analysis. There were 471 terms obtained from GO functional enrichment analysis, among which 248 related to biological processes, 125 related to molecular functions, and 98 related to cellular components. There were 299 signaling pathways obtained from KEGG pathway enrichment analysis. The active components of QHJTC were found spontaneously binding to the core targets.\u0000 Conclusions QHJTC can treat T2DM through multi-components, multi-targets, and multi-pathways.","PeriodicalId":204577,"journal":{"name":"Chinese medicine and natural products","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121645932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Effects of Bushen Culuan Prescription on Infertility Due to Decreased Ovarian Reserve of Kidney Deficiency and Liver Depression Pattern","authors":"Ya-ling Feng, Sujuan Ma","doi":"10.1055/s-0042-1757462","DOIUrl":"https://doi.org/10.1055/s-0042-1757462","url":null,"abstract":"\u0000 Objective The objective of this study was to explore the clinical effects of Bushen Culuan prescription on infertility due to decreased ovarian reserve of kidney deficiency and liver depression pattern.\u0000 Methods Totally 100 infertile patients with ovarian hypofunction treated from October 2019 to January 2022 were selected and divided into the observation group and the control group by a random number table. The control group was treated with estrogen sequential therapy, and the observation group was treated with Bushen Culuan prescription. The clinical efficacy, sex hormone levels including (follicle-stimulating hormone [FSH], luteinizing hormone [LH], and estradiol [E2]), ovarian function, ovarian blood flow status (peak systolic velocity [PSV], antral follicle count [AFC], arterial pulse index [PI], and resistance index [RI]), and pregnancy outcome in the two groups were compared and analyzed.\u0000 Results The total effective rate of the observation group (96.00%) was significantly higher than that of the control group (80.00%). The difference was statistically significant (p < 0.05). Before treatment, there was no significant difference in sex hormone levels (FSH, LH, E2, and FSH/LH), ovarian function (number of primary follicles, number of dominant follicles, ovulation number, and endometrial thickness), and ovarian blood flow (PSV, RI, PI, and AFC) between the two groups (p > 0.05). After treatment, the levels of serum hormones FSH, LH, E2, and FSH/LH decreased significantly in both groups. The number of primary follicles, dominant follicles, and ovulation increased significantly, and the thickness of endometrium decreased significantly; the indexes of PSV, RI, and AFC of ovarian blood flow increased significantly, and the PI index decreased significantly. The levels of each index in the observation group were better than those in the control group (p < 0.05). In the control group, 32 cases were pregnant within 1 year after treatment, and the pregnancy rate was 64.00%; 21 cases in the observation group were pregnant within 1 year after treatment, and the pregnancy rate was 42.00%; the pregnancy rate in the observation group was higher than that in the control group, and the difference was statistically significant (χ2 = 4.014, p = 0.045 < 0.05).\u0000 Conclusion Bushen Culuan prescription has a definite effect on infertility due to ovarian hypofunction. The action mechanism may involve multicomponent and multitarget stimulation to improve patients' ovarian function, regulate the level of sex hormones, and improve the pregnancy outcome.","PeriodicalId":204577,"journal":{"name":"Chinese medicine and natural products","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114534865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Study on the Action Mechanism of the Jinyingzi (Rosae Laevigatae Fructus)–Qianshi (Euryales Semen) Couplet Herbs on Membranous Nephropathy Based on Network Pharmacology","authors":"Haoyi Tian, Yun Tian","doi":"10.1055/s-0042-1757458","DOIUrl":"https://doi.org/10.1055/s-0042-1757458","url":null,"abstract":"\u0000 Objective Our objective was to explore the action mechanism of the Jinyingzi (Rosae Laevigatae Fructus)–Qianshi (Euryales Semen) couplet herbs in the treatment of membranous nephropathy (MN) based on network pharmacology.\u0000 Methods The active ingredients and targets of Jinyingzi (Rosae Laevigatae Fructus) and Qianshi (Euryales Semen) were screened by systematic pharmacology database and analysis platform. Online Human Mendelian Genetic database and GeneCards database were used to retrieve MN-related targets. The active ingredient-related targets and MN disease targets were introduced into Venny 2.1, and Wayne diagram was drawn. The intersection targets were the potential targets of the Jinyingzi (Rosae Laevigatae Fructus)–Qianshi (Euryales Semen) couplet herbs in the treatment of MN. The protein interaction network of potential targets was constructed, and the core targets were screened with String platform. Metascape platform was used for functional enrichment analysis of gene ontology (GO) and pathway enrichment analysis of Kyoto Encyclopedia of Genes and Genomes (KEGG). The “herb-active ingredient-target-pathway” networks were drawn by using Cytoscape software, and the key components, targets, and signaling pathways were screened.\u0000 Results A total of 8 active ingredients and 193 related targets in Jinyingzi (Rosae Laevigatae Fructus) and Qianshi (Euryales Semen) were screened out; a total of 1,621 targets of MN disease and 105 potential targets for the treatment of MN were obtained in the treatment with Jinyingzi (Rosae Laevigatae Fructus)–Qianshi (Euryales Semen) couplet herbs; 40 core targets were screened by protein–protein interaction network topology analysis; a total of 1,978 results were obtained by GO function enrichment analysis, and 206 signal pathways were obtained by KEGG pathway enrichment analysis and screening. The network topology analysis of “herb-active ingredient-target-pathway” showed that the key components included quercetin, kaempferol, β-sitosterol, etc.; the key targets included protein kinase Bα (AKT), mitogen-activated protein kinase 1 (MAPK1), B-cell lymphoma-2 (BCL2), prostaglandin-endoperoxide synthase 2 (PTGS2), etc.; the key pathways included advanced glycation end product/receptor of AGE signaling pathway, phosphatidyl inositol 3-kinase (PI3K)/AKT signaling pathway, MAPK signaling pathway, hypoxia-inducible factor-1 signaling pathway, Ras signaling pathway, nuclear factor kappa-B (NF-κB) signaling pathway, Toll-like receptors signaling pathway, p53 signaling pathway and vascular endothelial growth factor signaling pathway in the late stage of diabetic complications.\u0000 Conclusion The Jinyingzi (Rosae Laevigatae Fructus)–Qianshi (Euryales Semen) couplet herbs can regulate PI3K/AKT, MAPK, NF-κB signaling pathways in MN by targeting proteins of AKT1, MAPK8, PTGS2 through key components of quercetin, β-sitosterol, and kaempferol, so as to inhibit the overexpression of inflammatory factors in renal tissues, regulate ","PeriodicalId":204577,"journal":{"name":"Chinese medicine and natural products","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114196928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Meta-Analysis of Migraine Treated with Banxia Baizhu Tianma Decoction","authors":"Xue Chen, Zhe-yuan Liu, J Zhang, Juanjuan Chen, Xiude Qin, Feng Jiang","doi":"10.1055/s-0042-1757459","DOIUrl":"https://doi.org/10.1055/s-0042-1757459","url":null,"abstract":"\u0000 Objective Our objective was to systematically evaluate the efficacy and safety of Banxia Baizhu Tianma decoction in the treatment of migraine.\u0000 Methods The databases of China National Knowledge Infrastructure, VIP, WanFang, Chinese Biomedical Databases, PubMed, and EMbase were searched by computer, and randomized controlled trials that met the inclusion criteria were retrieved. The Cochrane bias risk assessment tool was used to evaluate the quality of the included studies. RevMan 5.3 software was used to conduct meta quantitative analysis of the included studies.\u0000 Results A total of 19 studies were included, with a total sample size of 1,635 cases, 821 cases in the treatment group and 814 cases in the control group. The results of meta-analysis showed that (1) the clinical effective rate of the single use of Banxia Baizhu Tianma decoction or western medicine combined with Banxia Baizhu Tianma decoction in treating migraine was better than that of western medicine alone (p < 0.001); (2) the improvement in cumulative number and days of vertigo in the treatment of migraine with Banxia Baizhu Tianma decoction was observed in the control group (p < 0.001). TSA results showed that Z-curve passed both the traditional threshold and Trial sequential analysis (TSA) threshold. In terms of adverse reactions, 55 cases were reported, including 12 cases in the treatment group and 43 cases in the control group, and no serious adverse reactions were found.\u0000 Conclusion Compared with the single use of western medicine therapy, the combination of Banxia Baizhu Tianma decoction and western medicine or the single use of Banxia Baizhu Tianma decoction could better improve the effective rate and showed good safety and low incidence of adverse reactions.","PeriodicalId":204577,"journal":{"name":"Chinese medicine and natural products","volume":"41 19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128487425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Progress on the Mechanism of the Effective Components of Duzhong (Eucommiae Cortex) on Lumbar Disk Herniation","authors":"Bowen Yang, Yanju Zhang, Hongxia Qi, Yang Zhang","doi":"10.1055/s-0043-1764131","DOIUrl":"https://doi.org/10.1055/s-0043-1764131","url":null,"abstract":"Abstract Duzhong (Eucommiae Cortex) is one of the most commonly used Chinese herb in the treatment of lumbar disk herniation (LDH). Both the single use of it and as a Chinese herbal compound have significant clinical efficacy. Its effective components including lignans, flavonoids, iridoid terpenes, polysaccharides, etc., participate in the treatment of LDH through multiple channels, which can effectively inhibit immune and inflammatory reactions, promote the repair of intervertebral disk bone tissues, protect neurological functions, enhance cell metabolism, regulate endocrine, etc. The signal pathways of Wnt/β-catenin, TNF, HL-1, MAPK, PI3K/AKT, and NF-κB may be also involved. The action mechanism of Duzhong (Eucommiae Cortex) on LDH is characterized by multiple paths, multiple targets, and multiple component cross-actions, but the direct effects of specific components of Duzhong (Eucommiae Cortex) on LDH pathological tissues have not been clarified in the existing studies. At present, the study on the efficacy of Chinese herbs has not yet included the chemical reactions among the pharmaceutical components and pharmaceutical processing, etc. Relevant experimental studies need to further extract the effective components through purification technology, analyze the target information between Duzhong (Eucommiae Cortex) and LDH through network pharmacology and biology, and strengthen the influence of different processing methods on the pharmaceutical effects of Chinese herbs to increase the choice of clinical medication. In the experimental study, the animal cell models were finely constructed, and the pathological targets of LDH were excavated, which was conducive to the development and application of new drugs.","PeriodicalId":204577,"journal":{"name":"Chinese medicine and natural products","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127666856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reflections on the Application of Chinese Medicine During the Epidemic of COVID-19","authors":"Shaohui Geng, Hanlin Shi, Shuangqing Yang, Yaoyang Li, Haixu Jiang, Heng Xu, Hesong Wang, Zhiming Li, Liping Yang","doi":"10.1055/s-0042-1759767","DOIUrl":"https://doi.org/10.1055/s-0042-1759767","url":null,"abstract":"Abstract Traditional Chinese medicine (TCM) has played an important role in the prevention and control of coronavirus disease 2019 (COVID-19) and has received considerable attention from all sectors of society. In the current situation of the global outbreak, it is crucial to promote the global application of TCM. However, the pandemic has also exposed various problems affecting the widespread acceptance of TCM. In this review, we summarize efforts to prevent and control COVID-19 by TCM and provide strategic guidance on how to promote its practice in the context of public health emergencies by (1) completing the system for evaluating the clinical efficacy of TCM; (2) transforming decoctions into Chinese patent medicines; (3) encouraging low-threshold traditional rehabilitation therapy; (4) strengthening communication and cooperation with the media. The aim of these approaches is to improve the rigor of TCM research and its dissemination, sharing the antiepidemic experience of TCM to the world, as well as increase the engagement of and acceptance by the masses. In this manner, TCM will not only aid in preventing and controlling COVID-19 but can also provide tools for coping with future public health emergencies.","PeriodicalId":204577,"journal":{"name":"Chinese medicine and natural products","volume":"231 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132351635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Qi Field Effect of Acupuncture Time-Acupoints-Space in the Treatment of Long Coronavirus Disease and Coronavirus Disease 2019 Vaccine Adverse Reactions","authors":"Miansheng Zhu","doi":"10.1055/s-0043-1762572","DOIUrl":"https://doi.org/10.1055/s-0043-1762572","url":null,"abstract":"Abstract Corona Virus disease 2019 (COVID-19) has become a serious challenge. On the one hand, there is not a single explanation of its pathological mechanism, which directly affects the treatment efficacy. On the other hand, the complicated symptoms of long COVID and COVID-19 vaccine adverse reactions involve multiple systems and the number of affected patients is large, which have attracted great attention. Acupuncture time-acupoints-space (ATAS) is a new acupuncture technique developed on the basis of four methods of day-prescription of acupoints (Na Jia method), hour-prescription of acupoints (Na Zi Method), eightfold methods of the sacred tortoise (Ling Gui Eight Methods), and eight methods of swift puncturing of needles (Fei Teng Eight Methods) in midnight-noon and ebb-flow doctrine (Zi Wu Liu Zhu). The main idea of ATAS is to use the orderly combination of time acupoints and space acupoints to construct a field to regulate qi movement and treat diseases through the qi field effect. In France, although traditional Chinese medicine cannot be directly used to treat COVID-19, hundreds of patients with long COVID and COVID-19 vaccine adverse reactions have been treated using the four methods of ATAS. With reference to the microcirculatory lesions in the pathological mechanism of COVID-19 in Western medicine, hour prescription of acupoints (Na Zi Method) of ATAS showed specific efficacy for long COVID.","PeriodicalId":204577,"journal":{"name":"Chinese medicine and natural products","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128431894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expert Consensus on the Interventional Treatment of Choledocholithiasis with Integrative Medicine","authors":"Bin Liu, Zhongmin Wang, Jinhe Guo, Honglei Wu, Kai Zhang, Tao Yu, Zhengguang Du, Wenxia Zhao, Long Jin, Chongzhong Liu, Zan Fu, Jian-qi Sun, Kun Gao, Haibo Shao, Duiping Feng, D. Shen, Hongling Jia, Yuliang Li","doi":"10.1055/s-0043-1764130","DOIUrl":"https://doi.org/10.1055/s-0043-1764130","url":null,"abstract":"Abstract Percutaneous transhepatic papillary balloon drainage (PTPBD) is a newly emerging interventional treatment modality for choledocholithiasis in China. Compared with other treatments, it has some advantages. Traditional Chinese medicine has been proven to have certain advantages in the treatment of choledocholithiasis, with reliable efficacy, few side effects, and a low recurrence rate. To standardize the clinical practice of choledocholithiasis, facilitate the application of PTPBD, and improve the diagnosis and treatment of integrative medicine, the Chinese College of Interventionalists organized multidisciplinary experts to discuss and formulate this consensus. This consensus aims to regulate the patient selection and technical process of PTPBD and the diagnosis and treatment scheme of integrative medicine.","PeriodicalId":204577,"journal":{"name":"Chinese medicine and natural products","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124972701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treating Benign Accumulation Pattern in Young and Middle-Aged Women According to the Theory of Yang Stagnation","authors":"Wenke Zhang, Xu-qin Cheng, Zhikun Li, Huiduo Zhao, Beibei Wang","doi":"10.1055/s-0043-1764129","DOIUrl":"https://doi.org/10.1055/s-0043-1764129","url":null,"abstract":"Abstract Benign breast nodules, thyroid nodules, and myoma of the uterus are similar in etiology and pathogenesis. These three diseases are classified according to accumulation patterns in traditional Chinese medicine theory and can be treated with the same prescription. Yang stagnation is the basic pathogenesis of benign accumulation patterns in young and middle-aged women. Its treatment principle should be “unblocking yang,” and its treating methods should include diffusing yang, warming yang, dissolving phlegm, and dissipating stasis, which can unblock yang qi and dissolve stasis. Meanwhile, heart-nourishing and mind-calming ingredients should be included in the prescriptions to improve the clinical manifestations.","PeriodicalId":204577,"journal":{"name":"Chinese medicine and natural products","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131190704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development Trend and Thinking of International Traditional Chinese Medicine in the Late and Postpandemic Era","authors":"Benjamin Binjiang Wu","doi":"10.1055/s-0043-1762570","DOIUrl":"https://doi.org/10.1055/s-0043-1762570","url":null,"abstract":"Abstract There are mainly following 10 aspects of the trends in the development of international traditional Chinese medicine (TCM) in the late and postepidemic era. (1) Rehabilitation intervention of TCM in the recovery period is the focus of international TCM clinical antiepidemic practice in the later stage of the epidemic. (2) The epidemic has accelerated the development of the internet toward high-tech online education and medical care. (3) The epidemic has forced overseas TCM to transform from the “agricultural era” to the “postindustrial era.” (4) It has become a trend that the proportion of theory courses in online teaching will increase dramatically. (5) The limited number of practical training courses and the simultaneous online and offline rotation of teaching will become a useful medium of exploration. (6) Online sharing of high-quality courses can save costs and is also the direction of future development. (7) It will become the norm for the adoption of online TCM conferences that break traditional barriers of locale and time zone. (8) The renewal of the heavy TCM clinical and teaching equipment is the trend of future development. (9) The involvement of finance and venture capital will catalyze the development of the field of corporate international chains of TCM and acupuncture. (10) Changes in the international political situation may affect the speed of the development of international Chinese medicine but will not stop its progress.","PeriodicalId":204577,"journal":{"name":"Chinese medicine and natural products","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121178047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}