Polymer Journal最新文献

{"title":"Twist, bind, and amplify: Mechanistic pathways toward the superamplification of asymmetry in host–guest systems","authors":"Nozomu Suzuki, Shuhei Koike","doi":"10.1038/s41428-026-01172-7","DOIUrl":"10.1038/s41428-026-01172-7","url":null,"abstract":"Chirality governs not only local static molecular structures but also dynamic conformational changes and communication between interacting components. This review presents a unified theoretical framework for twisted host–guest systems that explicitly incorporates right- and left- (P- and M-) asymmetry to describe nonlinear chiroptical phenomena. The concept is extended from a single twisted host to multiple twisted hosts, wherein three cooperative interplays (host–host, guest–guest, and host–guest) collectively give rise to not only conventional amplification of asymmetry but also a qualitatively distinct regime, referred to here as superamplification. By bridging molecular host–guest equilibria and polymeric helicity through a common cooperative framework, this review establishes a theoretical basis for understanding how local chiral bias evolves into macroscopic superamplification of asymmetry, with particular emphasis on elucidating the origin and mechanism of this remarkable nonlinear phenomenon that has long been experimentally recognized but is conceptually elusive. Superamplification of asymmetry refers to a cooperative chiral phenomenon in which a small initial enantiomeric imbalance induces a disproportionately large macroscopic chiral response. Unlike conventional amplification of asymmetry, superamplification arises from the coupling of asymmetry amplification with additional cooperative effects, such as mutually exclusive binding or extremely high enantioselectivity. This synergy suppresses heterochiral states and enforces homochiral organization, resulting in nonlinear chiroptical responses that far exceed those predicted based on the conventional amplification of asymmetry.","PeriodicalId":20302,"journal":{"name":"Polymer Journal","volume":"58 8","pages":"853-863"},"PeriodicalIF":3.1,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148667541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transparent CNF/PMMA composite plate prepared through pickering emulsion–assisted aqueous polymerization","authors":"Miyako Maruo, Takumi Iijima, Tsuguyuki Saito, Shuji Fujisawa","doi":"10.1038/s41428-026-01180-7","DOIUrl":"10.1038/s41428-026-01180-7","url":null,"abstract":"Cellulose nanofibers (CNFs) are biomass-derived nanoscale reinforcements that combine high optical transparency, excellent mechanical properties, and low thermal expansion, rendering them ideal candidates for reinforcing transparent polymers. However, achieving a uniform dispersion of CNFs in common transparent polymers, such as polymethyl methacrylate (PMMA), remains challenging owing to interfacial incompatibility and the requirement of complex multistep processes. In this study, we developed a straightforward aqueous polymerization strategy for preparing transparent CNF/PMMA composites on the basis of CNF-stabilized Pickering emulsions. The CNF/PMMA composite powders containing 2 or 5 wt% CNFs were obtained through the filtration-based recovery of the polymerized product, followed by drying. By heat molding these powders, transparent CNF/PMMA plates with mm-scale thicknesses were prepared. Compared with those of neat PMMA, the thermomechanical properties of the resulting composites significantly improved because of the uniform dispersion of the CNFs and the efficient formation of a percolating network. Compared with that of neat PMMA, the storage modulus of the 5 wt% CNF/PMMA composite increased by approximately 4500%, suggesting the formation of a stiff CNF network structure. This study highlights the effectiveness of Pickering emulsion templating for constructing nanostructured polymer composites with improved thermal and mechanical performance and their potential for transparent structural applications in the automotive, architectural, and optical fields. A straightforward aqueous polymerization strategy was developed for preparing transparent CNF/PMMA composites on the basis of CNF-stabilized Pickering emulsions. By heat-molding composite powders, transparent CNF/PMMA plates with mm-scale thicknesses were prepared. The resulting composites exhibited high optical transparency, with total light transmittance > 80% at 600 nm.","PeriodicalId":20302,"journal":{"name":"Polymer Journal","volume":"58 8","pages":"881-889"},"PeriodicalIF":3.1,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41428-026-01180-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148667575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transparent CNF/PMMA composite plate prepared through pickering emulsion–assisted aqueous polymerization","authors":"Miyako Maruo, Takumi Iijima, Tsuguyuki Saito, Shuji Fujisawa","doi":"10.1038/s41428-026-01180-7","DOIUrl":"10.1038/s41428-026-01180-7","url":null,"abstract":"Cellulose nanofibers (CNFs) are biomass-derived nanoscale reinforcements that combine high optical transparency, excellent mechanical properties, and low thermal expansion, rendering them ideal candidates for reinforcing transparent polymers. However, achieving a uniform dispersion of CNFs in common transparent polymers, such as polymethyl methacrylate (PMMA), remains challenging owing to interfacial incompatibility and the requirement of complex multistep processes. In this study, we developed a straightforward aqueous polymerization strategy for preparing transparent CNF/PMMA composites on the basis of CNF-stabilized Pickering emulsions. The CNF/PMMA composite powders containing 2 or 5 wt% CNFs were obtained through the filtration-based recovery of the polymerized product, followed by drying. By heat molding these powders, transparent CNF/PMMA plates with mm-scale thicknesses were prepared. Compared with those of neat PMMA, the thermomechanical properties of the resulting composites significantly improved because of the uniform dispersion of the CNFs and the efficient formation of a percolating network. Compared with that of neat PMMA, the storage modulus of the 5 wt% CNF/PMMA composite increased by approximately 4500%, suggesting the formation of a stiff CNF network structure. This study highlights the effectiveness of Pickering emulsion templating for constructing nanostructured polymer composites with improved thermal and mechanical performance and their potential for transparent structural applications in the automotive, architectural, and optical fields. A straightforward aqueous polymerization strategy was developed for preparing transparent CNF/PMMA composites on the basis of CNF-stabilized Pickering emulsions. By heat-molding composite powders, transparent CNF/PMMA plates with mm-scale thicknesses were prepared. The resulting composites exhibited high optical transparency, with total light transmittance > 80% at 600 nm.","PeriodicalId":20302,"journal":{"name":"Polymer Journal","volume":"58 8","pages":"881-889"},"PeriodicalIF":3.1,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41428-026-01180-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148667599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Twist, bind, and amplify: Mechanistic pathways toward the superamplification of asymmetry in host–guest systems","authors":"Nozomu Suzuki, Shuhei Koike","doi":"10.1038/s41428-026-01172-7","DOIUrl":"10.1038/s41428-026-01172-7","url":null,"abstract":"Chirality governs not only local static molecular structures but also dynamic conformational changes and communication between interacting components. This review presents a unified theoretical framework for twisted host–guest systems that explicitly incorporates right- and left- (P- and M-) asymmetry to describe nonlinear chiroptical phenomena. The concept is extended from a single twisted host to multiple twisted hosts, wherein three cooperative interplays (host–host, guest–guest, and host–guest) collectively give rise to not only conventional amplification of asymmetry but also a qualitatively distinct regime, referred to here as superamplification. By bridging molecular host–guest equilibria and polymeric helicity through a common cooperative framework, this review establishes a theoretical basis for understanding how local chiral bias evolves into macroscopic superamplification of asymmetry, with particular emphasis on elucidating the origin and mechanism of this remarkable nonlinear phenomenon that has long been experimentally recognized but is conceptually elusive. Superamplification of asymmetry refers to a cooperative chiral phenomenon in which a small initial enantiomeric imbalance induces a disproportionately large macroscopic chiral response. Unlike conventional amplification of asymmetry, superamplification arises from the coupling of asymmetry amplification with additional cooperative effects, such as mutually exclusive binding or extremely high enantioselectivity. This synergy suppresses heterochiral states and enforces homochiral organization, resulting in nonlinear chiroptical responses that far exceed those predicted based on the conventional amplification of asymmetry.","PeriodicalId":20302,"journal":{"name":"Polymer Journal","volume":"58 8","pages":"853-863"},"PeriodicalIF":3.1,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148667551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"p–n patterning strategies for single-walled carbon nanotubes for the fabrication of joint-free thermoelectric generators","authors":"Naoki Tanaka, Tsuyohiko Fujigaya","doi":"10.1038/s41428-026-01168-3","DOIUrl":"10.1038/s41428-026-01168-3","url":null,"abstract":"Single-walled carbon nanotubes (SWCNTs) exhibit exceptional electrical, thermal, and mechanical properties because of their one-dimensional electronic structure, making them promising materials for flexible thermoelectric generators (TEGs). Recent advances in molecular doping and device engineering have enabled joint-free TEGs in which p- and n-type regions are seamlessly formed within a continuous SWCNT film or fiber, thus eliminating interfacial resistance and improving mechanical robustness. Realizing such architectures requires precise spatial control of carrier polarity, driving the development of selective doping strategies, including solution processing, thermal evaporation, and plasma- or light-assisted dopant removal. This review highlights recent progress on these methods, with a particular focus on photo-induced electron doping using photobase generators (PBGs). In particular, PBG1, a representative PBG, enables mask-defined n-type conversion without damaging SWCNTs, provides excellent stability, and achieves micrometer-scale p–n patterning. The demonstrations of planar TEGs based on p–n-patterned SWCNTs confirm the feasibility of scalable, flexible thermoelectric devices. The remaining challenges include maintaining sufficient temperature gradients despite lateral heat spreading in SWCNT networks and ensuring long-term operational stability. Opportunities in dopant design, nanoscale junction engineering, and thermal management are also discussed as pathways toward practical SWCNT-based thermoelectric technologies. Photo-induced dopants are patterned onto SWCNT films through UV mask exposure, where local irradiation tunes the electronic states of the adsorbed species to generate defined p- and n-type regions. This photopatterning process creates seamless, joint-free p–n architectures within the SWCNT network, forming continuous pathways for charge transport. As a result, the patterned SWCNT films function as monolithic, junction-free thermoelectric materials suitable for constructing integrated SWCNT-based thermoelectric generators","PeriodicalId":20302,"journal":{"name":"Polymer Journal","volume":"58 9","pages":"1035-1048"},"PeriodicalIF":3.1,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41428-026-01168-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of surgical indocyanine green-dyed gauze using an autoclave and its near-infrared fluorescence properties","authors":"Hidekazu Yasunaga, Yoshihiko Tashiro, Shinji Ando","doi":"10.1038/s41428-026-01170-9","DOIUrl":"10.1038/s41428-026-01170-9","url":null,"abstract":"A near-infrared (NIR)-fluorescent gauze dyed with indocyanine green (ICG) was newly developed using an autoclave to prevent gauze remnants and serve as a landmark for rapid identification of the target area during surgery. The gauze samples were dyed with an aqueous ICG solution at variable concentrations at high temperatures of 121 − 132 °C and high water vapor pressures of 0.21 − 0.29 MPa to enhance NIR fluorescence (FL) and increase dyeability and fastness. The gauze dyed with an ICG concentration of 1.5 × 10–4 mol L–1 at 132 °C for 10–15 min exhibited the brightest FL, with a quantum yield of 3.9%. Although the color of the dyed gauze was nearly identical to that of undyed gauze, as estimated by optical density and K/S value, the FL intensity further increased after post-sterilization (PS) at 132 °C for 8 min. This enhancement was attributed to the dissolution of ICG aggregates and improved fixation on the cotton fibers. Furthermore, the high-temperature dyeing technique followed by PS effectively suppressed ICG leakage from the gauze when soaked in artificial body fluid. The NIR-FL emitted from the gauze was clearly observed through human tissue, approximately 10 mm or more in thickness. A near-infrared fluorescent surgical gauze was developed by dyeing cotton with indocyanine green (ICG) using an autoclave at 121–132 °C and 0.21–0.29 MPa. The optimal condition (1.5 × 10⁻⁴ mol L–1 ICG, 132 °C, 10–15 min) yielded the brightest fluorescence. Post-sterilization (PS) enhanced fluorescence by dissolving ICG aggregates and improving fixation. The gauze’s color remained similar to undyed samples, but fluorescence increased by post-sterilization. It emitted strong NIR signals through over 10 mm of tissue and showed minimal dye leakage in artificial body fluid, making it useful for surgical site identification and reducing gauze remnants.","PeriodicalId":20302,"journal":{"name":"Polymer Journal","volume":"58 8","pages":"963-973"},"PeriodicalIF":3.1,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41428-026-01170-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148667601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of surgical indocyanine green-dyed gauze using an autoclave and its near-infrared fluorescence properties","authors":"Hidekazu Yasunaga, Yoshihiko Tashiro, Shinji Ando","doi":"10.1038/s41428-026-01170-9","DOIUrl":"10.1038/s41428-026-01170-9","url":null,"abstract":"A near-infrared (NIR)-fluorescent gauze dyed with indocyanine green (ICG) was newly developed using an autoclave to prevent gauze remnants and serve as a landmark for rapid identification of the target area during surgery. The gauze samples were dyed with an aqueous ICG solution at variable concentrations at high temperatures of 121 − 132 °C and high water vapor pressures of 0.21 − 0.29 MPa to enhance NIR fluorescence (FL) and increase dyeability and fastness. The gauze dyed with an ICG concentration of 1.5 × 10–4 mol L–1 at 132 °C for 10–15 min exhibited the brightest FL, with a quantum yield of 3.9%. Although the color of the dyed gauze was nearly identical to that of undyed gauze, as estimated by optical density and K/S value, the FL intensity further increased after post-sterilization (PS) at 132 °C for 8 min. This enhancement was attributed to the dissolution of ICG aggregates and improved fixation on the cotton fibers. Furthermore, the high-temperature dyeing technique followed by PS effectively suppressed ICG leakage from the gauze when soaked in artificial body fluid. The NIR-FL emitted from the gauze was clearly observed through human tissue, approximately 10 mm or more in thickness. A near-infrared fluorescent surgical gauze was developed by dyeing cotton with indocyanine green (ICG) using an autoclave at 121–132 °C and 0.21–0.29 MPa. The optimal condition (1.5 × 10⁻⁴ mol L–1 ICG, 132 °C, 10–15 min) yielded the brightest fluorescence. Post-sterilization (PS) enhanced fluorescence by dissolving ICG aggregates and improving fixation. The gauze’s color remained similar to undyed samples, but fluorescence increased by post-sterilization. It emitted strong NIR signals through over 10 mm of tissue and showed minimal dye leakage in artificial body fluid, making it useful for surgical site identification and reducing gauze remnants.","PeriodicalId":20302,"journal":{"name":"Polymer Journal","volume":"58 8","pages":"963-973"},"PeriodicalIF":3.1,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41428-026-01170-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148667597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of cooling temperature on flow temperature and morphology of poly(L-lactic acid) gel formed by complex crystals with solvents","authors":"Yasuhiro Matsuda, Kaito Tamura, Kei Hosomi, Atsushi Sugita","doi":"10.1038/s41428-026-01171-8","DOIUrl":"10.1038/s41428-026-01171-8","url":null,"abstract":"Poly(L-lactic acid) (PLLA) was dissolved in N,N-dimethyl formamide at an elevated temperature, and cooled at different temperatures (−20 to 25 °C) for gelation. Viscoelastic measurements were carried out, and the flow temperature of the gel cooled approximately 0 °C was the highest among the gels prepared in this study. A fiber network structure formed from densely woven thin fibers was observed in the gel cooled approximately 0 °C using scanning electron microscopy. Similar fibrous structures were observed for all the gel samples prepared in this study, but their morphologies were slightly different from that of the gel cooled at 0 °C. Larger pores were observed in the gel cooled at −20 °C, and the fibers that formed in the gel cooled at 25 °C were thick and nonuniform. The pore area and fiber diameter evaluated by image analysis software supported these morphological differences. X-ray diffraction measurements and viscoelastic measurements were carried out for the gels cooled at different temperatures. The peak intensity assigned for the ε-crystals of PLLA became weaker for the gels cooled at lower temperatures. These results suggested that the structures of the fibrous network in the gels influence their flow temperature. Poly(L-lactic acid) was dissolved in N,N-dimethylformamide at an elevated temperature, and cooled at different temperatures (−20 to 25 °C) for gelation. Viscoelastic measurements were carried out, and the flow temperature of the gel cooled around 0 °C was highest among the gels prepared in this study. A fiber network structures formed by densely woven thin fibers was observed in the gel cooled around 0 °C by a scanning electron microscope.","PeriodicalId":20302,"journal":{"name":"Polymer Journal","volume":"58 8","pages":"875-880"},"PeriodicalIF":3.1,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148667595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of cooling temperature on flow temperature and morphology of poly(L-lactic acid) gel formed by complex crystals with solvents","authors":"Yasuhiro Matsuda, Kaito Tamura, Kei Hosomi, Atsushi Sugita","doi":"10.1038/s41428-026-01171-8","DOIUrl":"10.1038/s41428-026-01171-8","url":null,"abstract":"Poly(L-lactic acid) (PLLA) was dissolved in N,N-dimethyl formamide at an elevated temperature, and cooled at different temperatures (−20 to 25 °C) for gelation. Viscoelastic measurements were carried out, and the flow temperature of the gel cooled approximately 0 °C was the highest among the gels prepared in this study. A fiber network structure formed from densely woven thin fibers was observed in the gel cooled approximately 0 °C using scanning electron microscopy. Similar fibrous structures were observed for all the gel samples prepared in this study, but their morphologies were slightly different from that of the gel cooled at 0 °C. Larger pores were observed in the gel cooled at −20 °C, and the fibers that formed in the gel cooled at 25 °C were thick and nonuniform. The pore area and fiber diameter evaluated by image analysis software supported these morphological differences. X-ray diffraction measurements and viscoelastic measurements were carried out for the gels cooled at different temperatures. The peak intensity assigned for the ε-crystals of PLLA became weaker for the gels cooled at lower temperatures. These results suggested that the structures of the fibrous network in the gels influence their flow temperature. Poly(L-lactic acid) was dissolved in N,N-dimethylformamide at an elevated temperature, and cooled at different temperatures (−20 to 25 °C) for gelation. Viscoelastic measurements were carried out, and the flow temperature of the gel cooled around 0 °C was highest among the gels prepared in this study. A fiber network structures formed by densely woven thin fibers was observed in the gel cooled around 0 °C by a scanning electron microscope.","PeriodicalId":20302,"journal":{"name":"Polymer Journal","volume":"58 8","pages":"875-880"},"PeriodicalIF":3.1,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148667542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New strain Cupriavidus necator B-15081—a producer of single-cell protein and degradable polyhydroxyalkanoates on waste fish oil","authors":"Natalia Zhila, Kristina Sapozhnikova, Evgeniy Kiselev, Anzhelika Kolmakova, Tatiana Volova","doi":"10.1038/s41428-026-01178-1","DOIUrl":"10.1038/s41428-026-01178-1","url":null,"abstract":"This article presents the results of the synthesis of biological macromolecules, namely, single-cell protein (SCP) and degradable polyhydroxyalkanoates (PHAs), by a new strain of Cupriavidus necator B-15081 with high lipase activity on waste fish oil (WFO). Bacteria were cultivated in flasks on medium containing 20.0 g/L WFO obtained from Sprattus sprattus and Scomber scombrus waste under different concentrations of the nitrogen source (urea) to modify the C/N ratio in the medium and the direction of constructive cell metabolism. On a medium with a urea concentration of 1.5 g/L, the bacterial biomass concentration reached 7.2 ± 0.3 g/L, the intracellular protein content was 50.7%, and the amino acid composition was complete with a full set of amino acids, including essential ones. In a slowly growing culture under nitrogen deficiency, the total biomass concentration reached 12.0 ± 0.9 g/L, and the intracellular content of PHAs was 86.4 ± 5.9%. Bacteria synthesized P(3HB) homopolymers that exhibited a reduced degree of crystallinity (49–50%). Moreover, the completeness of WFO use by bacteria exceeded 80%. According to the studied parameters, the strain C. necator B-15081 is a promising producer of target products on a new renewable substrate. A new wild-type strain of Cupriavidus necator B-15081 with high lipase activity was cultivated in flasks on medium containing waste fish oil (WFO) obtained from Sprattus sprattus and Scomber scombrus waste. When bacteria were cultivated in a complete nutrient medium, bacteria accumulated up to 60.0% of protein, characterized by a complete amino acid profile. When bacteria were cultivated under nitrogen deficiency, a high content of biopolymer (polyhydroxyalkanoates, PHAs) was obtained.","PeriodicalId":20302,"journal":{"name":"Polymer Journal","volume":"58 8","pages":"943-953"},"PeriodicalIF":3.1,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148667600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}