PLoS ONE最新文献

{"title":"The hidden challenges of return migration: Linguistic and academic re-adaptation of Syrian students to the Arabic Education System.","authors":"Sevda Dolapcioglu, Yunus Emre Akbana, İlayda Uzun, Gülten Koşar","doi":"10.1371/journal.pone.0361042","DOIUrl":"10.1371/journal.pone.0361042","url":null,"abstract":"<p><p>While extensive research has examined refugee students' educational adaptation in host countries, the educational reintegration phase following voluntary return remains underexplored. This qualitative study investigates the linguistic and academic adaptation experiences of Syrian students transitioning from Turkish-medium education in Türkiye to Arabic-medium schooling in Syria after voluntary return. The study addresses an overarching question: how do returnee students experience the linguistic, academic, social, and psychosocial dimensions of this reverse educational transition? Using an exploratory qualitative design, data were collected through a seven-item open-ended written questionnaire from 15 middle-school students who had received several years of formal schooling in Türkiye. Qualitative content analysis revealed that return does not constitute a simple linguistic recovery, but rather a reverse academic transition characterized by profound difficulties with academic Arabic, conceptual transfer, written production, and in-class assessment practices. The findings indicate that students' challenges were shaped not only by uneven Arabic literacy development but also by curriculum misalignment, pedagogical practices that participants perceived as more teacher-directed, limited peer interaction, and assessment practices that they perceived as unclear. Furthermore, psychosocial pressures, including re-migration-related distress, concentration difficulties, and increased family responsibilities, complicated their academic adaptation. Ultimately, these struggles reflect systemic institutional and contextual mismatches rather than individual deficits. By conceptualizing return as a distinct educational phase, this study contributes to the broader discourses on refugee education and bilingualism. The implications underscore the critical need for academic Arabic bridging programs, background-sensitive assessment frameworks, psychosocially responsive pedagogies, and school-based psychosocial support to ensure equitable reintegration into Arabic-medium schooling.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 10","pages":"e0361042"},"PeriodicalIF":2.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-monotonic thickness dependence of MoS2-Sb contact resistance driven by bandgap and interlayer transport.","authors":"Luhao Liu, Zhengyi He, Yixiang Li, Shengsheng Lin, Songlin Li","doi":"10.1371/journal.pone.0360960","DOIUrl":"10.1371/journal.pone.0360960","url":null,"abstract":"<p><p>Contact resistance at metal-two-dimensional semiconductor interfaces is a major factor limiting the performance of emerging two-dimensional electronic devices. Understanding how material thickness influences contact behavior is therefore essential for device optimization. Here, we systematically investigate the layer-dependent contact resistance of MoS2-Sb interfaces using MoS2 field-effect transistors with different layer numbers. Contact resistance was extracted using the transmission line method and compared for devices fabricated on SiO2 and HfO2 gate dielectrics. The results reveal a pronounced non-monotonic dependence of contact resistance on the MoS2 layer number. As the layer number increases from one to three, the contact resistance decreases and reaches a minimum value of 308 Ω·μm for trilayer MoS2, while further increasing the thickness leads to a rise in resistance. Analysis of the electronic band structure and interlayer transport mechanisms indicates that this behavior originates from the competition between bandgap reduction and increasing interlayer transport resistance. In the few-layer regime, bandgap narrowing lowers the Schottky barrier and reduces contact resistance, whereas in thicker layers the growing interlayer resistance dominates carrier transport. These findings provide important insight into thickness-dependent contact physics in two-dimensional semiconductors and offer practical guidance for optimizing contact engineering and channel thickness in next-generation electronic devices.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 10","pages":"e0360960"},"PeriodicalIF":2.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A retrospective epidemiological study of screening-derived solid cancer incidence proxy rates in South Korea before and after COVID-19 using Korean National Health Insurance Service data.","authors":"Hyeran Jung, Minsun Jung","doi":"10.1371/journal.pone.0360040","DOIUrl":"10.1371/journal.pone.0360040","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic disrupted cancer screening and diagnostic pathways globally. Aggregate screening-derived indicators require cautious interpretation because they do not represent confirmed cancer registry incidence but might reflect program participation, referral patterns, and denominator composition.</p><p><strong>Objective: </strong>To evaluate pre- and post-COVID-19 changes in selected solid cancer screening-derived incidence proxy rates in South Korea, and to estimate model-based proxy rates through 2028.</p><p><strong>Methods: </strong>This retrospective ecological longitudinal study analyzed publicly available aggregate annual cancer-screening statistics from the Korean National Health Insurance Service (NHIS) and Korean Statistical Information Service (KOSIS) for six solid cancer programs (stomach, liver, colorectal, breast, cervical, and lung cancer). Annual proxy rates per 100,000 screened or eligible persons were calculated. Pre-COVID (2010-2019) and post-COVID (2020-2024) means were compared using Welch t-tests with Mann-Whitney U sensitivity analyses. Ordinary least-squares (OLS) forecasts were generated for 2025-2028. Interrupted time-series analysis was not feasible owing to an insufficient post-COVID observation window.</p><p><strong>Results: </strong>Post-COVID changes in proxy rates were heterogeneous across selected programs. Breast cancer proxy rates increased by 17.1% (Welch p = 0.002) and liver cancer proxy rates by 83.6% (Welch p = 0.002); the liver cancer increase reflects denominator restriction to a high-risk population rather than a true epidemiological surge. Stomach cancer decreased by 23.3% (Welch p = 0.001), cervical cancer by 56.9% (Welch p = 0.005), and colorectal cancer by 25.8% (Welch p = 0.007). Lung cancer data were available only from 2019 to 2024 (program inception) and were interpreted descriptively.</p><p><strong>Conclusions: </strong>Aggregate South Korean national screening data show pandemic-era temporal associations with heterogeneous changes in selected solid cancer program proxy rates. These findings support an indirect screening-disruption and ascertainment interpretation rather than causal proof of a direct COVID-19 effect on solid cancer incidence.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 10","pages":"e0360040"},"PeriodicalIF":2.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging material culture networks and social networks in archaeology.","authors":"Robert J Bischoff, Cecilia Padilla-Iglesias","doi":"10.1371/journal.pone.0358860","DOIUrl":"10.1371/journal.pone.0358860","url":null,"abstract":"<p><p>This study examines whether material culture can serve as a proxy for past social interaction. Using the ArchMatNet agent-based model, we simulate social behavior in small-scale communities and resulting material culture production, then compare social and material culture networks. We compare networks using graph correlation and the quadratic assignment procedure, evaluate parameter effects with generalized additive models, and assess underlying structures with exponential random graph models. Within this simulated system, results show strong correlations between social interaction networks and material culture networks, especially when material culture traits are sufficiently variable. However, correlations weaken under some conditions, particularly low material culture variation, indicating limits to archaeological network inference. Key factors include interaction frequency, learning strategy, and trait visibility. These results characterize hypothetical relationships generated under the model's assumptions; they do not constitute empirical validation. They highlight both the promise and the constraints of using material culture as a proxy for social networks and underscore the need for empirical testing and careful attention to network structure.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 10","pages":"e0358860"},"PeriodicalIF":2.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifestyle factors and clustered patterns of body shape change in Korean adults: A longitudinal observational study.","authors":"Jaeho Lee, Kyoungsik Jeong, Youngseop Lee, Younghwa Baek","doi":"10.1371/journal.pone.0360853","DOIUrl":"10.1371/journal.pone.0360853","url":null,"abstract":"<p><strong>Background: </strong>Obesity is a major health problem driven by lifestyle habits and changes in body composition, particularly increased body fat mass and reduced skeletal muscle mass. Body mass index alone cannot fully characterize adiposity distribution or changes in muscle mass. Body-shape indicators such as waist circumference, waist-to-hip ratio, and waist-to-height ratio predict metabolic and cardiovascular disease risk; however, few studies have assessed longitudinal changes in these measures together with lifestyle factors. In this study, we aimed to identify clusters of body-shape change using 2-year follow-up data from Korean adults and to elucidate the body-composition and lifestyle factors underlying these changes.</p><p><strong>Methods: </strong>K-means cluster analysis was applied to 1,404 participants in the Korean Medicine Daejeon Citizen Cohort using 2-year changes in body mass index, waist circumference, hip circumference, waist-to-hip ratio, waist-to-height ratio, and body weight. Baseline body shape, body composition, and lifestyle indicators were compared across clusters, and multinomial logistic regression was used to identify variables associated with cluster membership.</p><p><strong>Results: </strong>Three clusters were identified: Stable (48.0%), Adiposity-Increasing (31.0%), and Adiposity-Decreasing (21.0%). At baseline, cluster membership was significantly associated with body fat mass. Over follow-up, changes in body fat mass and skeletal muscle mass showed strong associations with cluster assignment. In addition, clinically meaningful worsening in sleep quality (increase of ≥2.5 points in the Pittsburgh Sleep Quality Index) and reduced physical activity (decrease in activity as measured by the Global Physical Activity Questionnaire) were significantly associated with the Adiposity-Increasing cluster.</p><p><strong>Conclusions: </strong>Changes in body composition, especially body fat mass and skeletal muscle mass, were closely associated with body-shape trajectories, while worsening sleep quality and declining physical activity were associated with the Adiposity-Increasing trajectory. These findings support an integrative approach that considers body shape, body composition, and modifiable lifestyle factors when characterizing adiposity-related trajectories and designing tailored lifestyle interventions.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 10","pages":"e0360853"},"PeriodicalIF":2.8,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of construction response for mechanized construction of metro connecting passages.","authors":"Lingbing Yi, Xiaochen Liu, Cai Yi, Peng Zhang, Lu Han","doi":"10.1371/journal.pone.0360916","DOIUrl":"10.1371/journal.pone.0360916","url":null,"abstract":"<p><p>To investigate the influence of mechanized pipe jacking construction for connecting passages in weathered granite strata on the settlement and deformation of left and right shield sections of metro tunnels and ground surface, this paper takes the pipe jacking project of No.1 connecting passage in a typical weathered granite stratum as the research background. Numerical analysis software was used to model and analyze the whole construction process of the connecting passage using the mechanized pipe jacking method. The accuracy of the numerical model was verified by comparison with field monitoring data. On this basis, the influence laws of stratum cohesion, internal friction angle, clear distance between main tunnels, and burial depth on the deformation of the main tunnels and ground surface were systematically analyzed. The results show that: 1) The tunnel at the launching end experienced two sudden deformations during the portal breaking stage, with the bending moment increasing sharply first and then decreasing slowly; the deformation at the receiving end increased linearly with the pipe jacking advance, and reached the peak synchronously with the bending moment at the moment of portal breaking. 2) A centrally symmetrical settlement trough was formed on the ground surface, with a maximum settlement value of 2.3 mm; the maximum vertical and horizontal deformations of the main tunnel were 1.7 mm and 1.4 mm, respectively. 3) The improvement of stratum strength can reduce ground surface settlement but increase the horizontal deformation of the tunnel; the increase of the clear distance between main tunnels leads to the expansion of the settlement trough width; the increase of burial depth reduces ground surface settlement while increases the horizontal deformation of the tunnel.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 10","pages":"e0360916"},"PeriodicalIF":2.8,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149195867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive autoantibodies before the diagnosis of type I diabetes in adults.","authors":"Peter D Burbelo, Robert Nee, Julio A Huapaya, Richard Plasse, Myungjin Kim, Sarah Gordon, Giovanni Di Pasquale, John A Chiorini, Stephen Olson","doi":"10.1371/journal.pone.0352531","DOIUrl":"10.1371/journal.pone.0352531","url":null,"abstract":"<p><p>Recent epidemiologic studies indicate that adult-onset type 1 diabetes (AOT1D) is more common than childhood-onset type 1 diabetes, yet it remains clinically underrecognized. Because little is known about the emergence of islet autoantibodies in AOT1D, we conducted a retrospective study using electronic medical records from the United States Military Health System and longitudinal serum samples from 169 individuals with AOT1D and 40 healthy controls obtained from the Department of Defense Serum Repository. Among 643 prediagnostic samples from individuals with AOT1D, IA-2 autoantibodies were the most prevalent (50%), followed by GADA (46%), IA-2β (34%), ZnT8-R (27%), and ZnT8-W (15%). Overall, 85% (144/169) of subjects were seropositive for at least one autoantibody prior to diagnosis. Analysis of the earliest available sample from all of the AOT1D cases, grouped into 5-year intervals preceding diagnosis, demonstrated a progressive increase in seropositivity over time: 38% of subjects were seropositive more than 20 years before diagnosis, increasing to 44% at 20-15 years, 59% at 15-10 years, 73% at 10-5 years, and 91% within 5 years of diagnosis. Among the 144 seropositive individuals, positivity for two or more autoantibodies was the most common pattern, occurring in 50% (72/144) of cases. Isolated GADA positivity (22%) and isolated IA-2/IA-2β positivity (24%) occurred at similar frequencies, whereas isolated ZnT8 positivity was uncommon (4%). Temporal analysis showed that isolated GADA positivity appeared earliest, with a median onset of 7.9 years before diagnosis, whereas multiple-autoantibody positivity, IA-2/IA-2β positivity, and ZnT8 positivity emerged later, with median onsets of 4.6, 4.5, and 1.9 years before diagnosis, respectively. These findings extend observations from pediatric type 1 diabetes to adults and demonstrate that AOT1D-associated autoimmunity often begins decades before clinical diagnosis, highlighting a potentially important window for risk stratification and preventive intervention.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 10","pages":"e0352531"},"PeriodicalIF":2.8,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149195926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traffic surveillance video-based a unified road accident detection, classification, and vehicle tracking framework using an optimized spatio-temporal attention mechanism.","authors":"Chokkakula Devi, Gowri S","doi":"10.1371/journal.pone.0357111","DOIUrl":"10.1371/journal.pone.0357111","url":null,"abstract":"<p><p>In recent days, vehicular accident detection has materialized because of the unique and intriguing application potential in the evolution of Intelligent Transportation Systems (ITS). To monitor and respond to the event of a fatal accident, real-world traffic surveillance footage requires continuous analysis. In this research, the road accident from the traffic surveillance video is detected, classified, and vehicle tracked using an efficient and innovative model. The surveillance videos are gathered from the CCTV Footage dataset, which is a publicly available dataset. The gathered videos are directly applied to the Spatio-Temporal Attention-based Adaptive Yolov9 with SE-InceptionNet and Deep SORT (AYSIDSORT) model for detecting, classifying and tracking traffic accidents very effectively. The developed network allows accurate detection and tracking of vehicles in real-time, which ensures the continuous traffic flow without losing moving objects. The variables of the proposed AYSIDSORT model are tuned by the developed Generation Probability-based Equilibrium Optimizer (GP-EO) to improve the detection and classification performance. The exact location of the accident is sent to the appropriate entities using an Internet of Things (IoT) platform to provide a timely rescue for the affected individual. Here, the proposed framework acts as a computer vision-based accident detection and tracking framework with potential IoT integration to find the exact location of the accident, which helps to provide a timely rescue for the affected individual. The effectiveness of the offered approach is validated with various baseline detection models. The accuracy of the suggested AYSIDSORT reaches to 95% in the 100th epoch, whereas there is a slight variation in the accuracy values when the batch size is varied from 4 to 128. The outcomes show that the designed framework is better than existing methods.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 10","pages":"e0357111"},"PeriodicalIF":2.8,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Analysis of the AP2/ERF Transcription Factor Family in Schisandra chinensis and Its Implications for secondary metabolism.","authors":"Kai Qian, Yifen Huang, Pengfei Zhu, Jing Wan, Jun Cheng, Zhuohang Li, Wensen Xie, Chengying Shan, Bin Chen, Yusong Shen, Wei Nie","doi":"10.1371/journal.pone.0361017","DOIUrl":"10.1371/journal.pone.0361017","url":null,"abstract":"<p><p>The AP2/ERF transcription factor superfamily is integral to plant secondary metabolism; however, its comprehensive genomic characterization in Schisandra chinensis-a medicinal plant esteemed for its dibenzocyclooctadiene (DBCOD) lignans with a wide range of pharmacological properties-has not yet been conducted. In this study, we identified a total of 144 ScAP2/ERF genes from the high-quality, chromosome-level genome of S. chinensis. These genes were categorized into five subfamilies (ERF, DREB, AP2, RAV, and Soloist) through phylogenetic analysis with Arabidopsis thaliana. Conserved motif analysis confirmed the presence of the characteristic AP2 domain in all ScAP2/ERF proteins, with members of the AP2 subfamily containing two AP2 domains and RAV members featuring both AP2 and B3 domains. Chromosomal localization analysis revealed an uneven distribution of these genes across 14 chromosomes, with clusters identified on chromosomes 1, 2, 6, 10, 11, and 13. Cis-acting element analysis demonstrated an enrichment of light-responsive, MeJA-responsive, ABA-responsive, and anaerobic induction elements in the promoters of ScAP2/ERF genes. Synteny analysis identified 26 pairs of segmentally duplicated genes within the S. chinensis genome and 39 orthologous pairs with A. thaliana. Expression profiling across roots, stems, leaves, and fruits revealed distinct tissue-specific expression patterns. Of the 144 identified genes, 122 (84.7%) were detectably expressed in at least one tissue; among them, ten exhibited notably high expression in fruit tissues, suggesting their potential regulatory roles in the accumulation of pharmacologically active compounds in the medicinal fruit. This study represents a comprehensive genome-wide identification of the AP2/ERF family in S. chinensis, thereby establishing a foundational framework for understanding its evolutionary history and functional diversification. Furthermore, it offers candidate genes for subsequent functional validation in the regulation of their potential roles in regulating secondary metabolism.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 10","pages":"e0361017"},"PeriodicalIF":2.8,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a novel body temperature sensor (CORE) in dogs under general anesthesia following premedication with dexmedetomidine or acepromazine: A pilot study.","authors":"Chloe R Dupleix, Jacob P Rastas, Qianqian Zhao, Robert Young, Rebecca A Johnson","doi":"10.1371/journal.pone.0360808","DOIUrl":"10.1371/journal.pone.0360808","url":null,"abstract":"<p><p>Core body temperature monitoring in anesthetized dogs is a vital part of physiological evaluation. Depending on the procedure and patient positioning, consistent core temperature measurements can be difficult to obtain. The objective of this study was to evaluate the reliability and clinical validity of a wireless, non-invasive, superficial heat flux-based thermometric device (CORE, greenTEG AG, Rümlang, Switzerland). Three healthy beagle dogs were premedicated with either dexmedetomidine or acepromazine prior to induction with intravenous propofol and isoflurane maintenance. They were monitored every five minutes with pulse oximetry, non-invasive blood pressure, electrocardiography, and capnometry. Rectal thermometry and temperatures from the CORE sensor placed on clipped and unclipped skin over the jugular veins were measured every three minutes for up to 120 minutes following induction. Based on the correlation coefficient for repeated measures (rrm) and the Shrout-Fleiss intraclass correlation coefficient (ICC), in dogs administered acepromazine, there was good, statistically significant correlation and reliability between rectal and clipped CORE temperatures (rrm = 0.81, P < 0.0001; ICC = 0.78) and rectal and unclipped CORE temperatures (rrm = 0.79, P < 0.0001; ICC = 0.85). In dogs administered dexmedetomidine, although values were correlated (rrm = 0.30, P < 0.0001), there was poor reliability (ICC = 0.28) between rectal and clipped CORE temperatures which improved if dogs were unclipped (rrm = 0.48, P < 0.0001; ICC = 0.88). Clinically acceptable Bland-Altman agreements were found between rectal and unclipped CORE methods. These preliminary results suggest that the CORE sensor may provide an alternative method for assessing core body temperatures in unclipped, anesthetized dogs.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 10","pages":"e0360808"},"PeriodicalIF":2.8,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}