PLoS ONE最新文献

筛选
英文 中文
Correction: Yield of soybean genotypes identified through GGE biplot and path analysis.
IF 2.9 3区 综合性期刊
PLoS ONE Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1371/journal.pone.0320098
Welder José Dos Santos Silva, Francisco de Alcântara Neto, Wahidah H Al-Qahtani, Mohammad K Okla, Abdulrahman Al-Hashimi, Paulo Fernando de Melo Jorge Vieira, Geraldo de Amaral Gravina, Alan Mario Zuffo, Alexson Filgueiras Dutra, Leonardo Castelo Branco Carvalho, Ricardo Silva de Sousa, Arthur Prudêncio de Araujo Pereira, Wallace de Sousa Leite, Gabriel Barbosa da Silva Júnior, Adriana Conceição da Silva, Marcos Renan Lima Leite, Renato Lustosa Sobrinho, Hamada AbdElgawad
{"title":"Correction: Yield of soybean genotypes identified through GGE biplot and path analysis.","authors":"Welder José Dos Santos Silva, Francisco de Alcântara Neto, Wahidah H Al-Qahtani, Mohammad K Okla, Abdulrahman Al-Hashimi, Paulo Fernando de Melo Jorge Vieira, Geraldo de Amaral Gravina, Alan Mario Zuffo, Alexson Filgueiras Dutra, Leonardo Castelo Branco Carvalho, Ricardo Silva de Sousa, Arthur Prudêncio de Araujo Pereira, Wallace de Sousa Leite, Gabriel Barbosa da Silva Júnior, Adriana Conceição da Silva, Marcos Renan Lima Leite, Renato Lustosa Sobrinho, Hamada AbdElgawad","doi":"10.1371/journal.pone.0320098","DOIUrl":"10.1371/journal.pone.0320098","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1371/journal.pone.0274726.].</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 3","pages":"e0320098"},"PeriodicalIF":2.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deaf children with cochlear implants in Chile: A national analysis of health determinants and outcomes in the Latin American context.
IF 2.9 3区 综合性期刊
PLoS ONE Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1371/journal.pone.0317238
Mario Bustos-Rubilar, Fiona Kyle, Merle Mahon
{"title":"Deaf children with cochlear implants in Chile: A national analysis of health determinants and outcomes in the Latin American context.","authors":"Mario Bustos-Rubilar, Fiona Kyle, Merle Mahon","doi":"10.1371/journal.pone.0317238","DOIUrl":"10.1371/journal.pone.0317238","url":null,"abstract":"<p><p>Deafness from birth represents a critical challenge for children's communication, with substantial public health considerations. One intervention has been cochlear implants (CI) for children with severe to profound deafness. Since 2008, Chile has implemented regulations to provide a CI at an early age. However, wide variability exists in factors and expected outcomes without previous national studies. This study aimed to characterise deaf children with CI in Chile and evaluate the impact of CI on speech perception and production, social inclusion, and parental satisfaction. We conducted a prospective study using hospital clinical records and an online questionnaire with 107 deaf children under 15 who had received CIs from 2017 to 2019. We characterised factors and outcomes and investigated the relationship between demographic, audiological, and social determinants of health and outcomes, including communication at home, CAPII, SIR, Geers and Moog Scale, Social Inclusion, and Parental Satisfaction. Our study showed a national profile of deaf children with CI, representing 70% of those implanted from 2017 to 2019. CI beneficiaries lived in more developed boroughs (.54) compared to the national average (.37). Communication and speech perception outcomes varied and were concerning, yet more positive outcomes were presented for social inclusion and parental satisfaction. We found an association between the measured outcomes and children's age, a socio-economic factor, CI use and CI training. This novel national study supports integrating public services close to each beneficiary's borough to improve outcomes with the device. CI use and parental training might be crucial measures during rehabilitation treatment.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 3","pages":"e0317238"},"PeriodicalIF":2.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and associated factors of chronic kidney disease among diabetes mellitus patients in Ethiopia: A systematic review and meta-analysis.
IF 2.9 3区 综合性期刊
PLoS ONE Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1371/journal.pone.0315529
Habtamu Wagnew Abuhay, Melaku Kindie Yenit, Mihret Melese, Gebrie Getu Alemu, Fantu Mamo Aragaw
{"title":"Prevalence and associated factors of chronic kidney disease among diabetes mellitus patients in Ethiopia: A systematic review and meta-analysis.","authors":"Habtamu Wagnew Abuhay, Melaku Kindie Yenit, Mihret Melese, Gebrie Getu Alemu, Fantu Mamo Aragaw","doi":"10.1371/journal.pone.0315529","DOIUrl":"10.1371/journal.pone.0315529","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic kidney disease (CKD) is a major public health concern worldwide, especially among people with diabetes mellitus (DM), which is the main cause of morbidity and mortality. In Ethiopia, the burden of CKD on DM patients is compounded by a variety of socioeconomic and healthcare-related issues. Despite the increased risk of developing CKD in DM patients, comprehensive studies on the prevalence and associated factors of CKD in this population are rare. To address this gap, this study aimed to estimate the pooled prevalence and associated factors of CKD among DM patients in Ethiopia.</p><p><strong>Methods: </strong>This systematic review and meta-analysis was carried out through an investigation of published studies in Ethiopia. A systematic literature search was performed using electronic databases such as PubMed, EMBASE, Scopus, and Google Scholar. A random-effects model was used to estimate the pooled prevalence of CKD and the odds ratio (OR) with a 95% confidence interval. The I² statistic was used to measure heterogeneity among the included studies, with a p-value < 0.05 indicating statistical significance. Publication bias was evaluated via a funnel plot and Egger's test, and subgroup, sensitivity, and meta-regression analyses were also performed.</p><p><strong>Results: </strong>Out of the 19 included studies, the estimated pooled prevalence of CKD among DM patients in Ethiopia was 18% (95% CI 14.0, 22.0). In addition, age ≥ 60 years (OR = 3.07, 95% CI: 2.44, 3.87), rural residence (OR = 1.40, 95% CI: 1.01, 1.95), duration of DM > 5 years (OR = 2.47, 95% CI: 1.62, 3.77), proteinuria (OR = 3.30, 95% CI: 2.23, 4.88), HDL-C level < 40 mg/dL (OR = 3.08, 95% CI: 2.28, 4.16), and family history of CKD (OR = 2.58, 95% CI: 1.62, 4.09) were factors significantly associated with the prevalence of CKD among DM patients.</p><p><strong>Conclusion: </strong>The prevalence of CKD in Ethiopia was high, affecting nearly two in five individuals with diabetes. In addition, factors such as older age, rural residence, longer DM duration, positive proteinuria, lower HDL-C levels, and a family history of CKD were significantly associated with CKD prevalence. Therefore, targeted public health interventions, such as screening, education, and awareness programs, are highly recommended to mitigate this problem.</p><p><strong>Systematic review registrations: </strong>PROSPERO (2024: CRD42024576958).</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 3","pages":"e0315529"},"PeriodicalIF":2.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction: International trade and finance exploration using network model of computer trade platform.
IF 2.9 3区 综合性期刊
PLoS ONE Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1371/journal.pone.0319662
{"title":"Retraction: International trade and finance exploration using network model of computer trade platform.","authors":"","doi":"10.1371/journal.pone.0319662","DOIUrl":"10.1371/journal.pone.0319662","url":null,"abstract":"","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 3","pages":"e0319662"},"PeriodicalIF":2.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study of artificial light plant factories and greenhouse seedlings of SAOPOLO tomato.
IF 2.9 3区 综合性期刊
PLoS ONE Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1371/journal.pone.0314808
Jun Zou, Wenbin Liu, Dawei Wang, Shipeng Luo, Shaojun Yang, Xiaotao Ding, Mingming Shi
{"title":"Comparative study of artificial light plant factories and greenhouse seedlings of SAOPOLO tomato.","authors":"Jun Zou, Wenbin Liu, Dawei Wang, Shipeng Luo, Shaojun Yang, Xiaotao Ding, Mingming Shi","doi":"10.1371/journal.pone.0314808","DOIUrl":"10.1371/journal.pone.0314808","url":null,"abstract":"<p><p>In the summer, the high temperatures, high humidity, frequent rainstorms, and typhoons in the East China region limit the growth of SAOPOLO tomato seedlings. By using a plant factory combined with an LED artificial light environment, the light environment can be effectively controlled to produce high-quality seedlings. This study investigates the growth and energy consumption of tomato seedlings in an artificial light plant factory. The experiment compared tomato seedlings cultivated in the artificial LED light environment of a plant factory with those grown in a semi-enclosed seedling greenhouse. The study meticulously examined the actual growth and development processes of the tomato seedlings, systematically tracking and recording the specific impacts of different cultivation environments on the seedlings' growth and development. Additionally, the experiment followed up on the fruiting conditions of the subsequent tomato plants. The experimental results show that compared to tomato seedlings grown in a greenhouse, those cultivated in the artificial light plant factory grew more slowly before grafting, characterized by slightly lower plant height, relatively smaller leaf area, and slightly thinner stems. However, after grafting, the growth rate of the tomato seedlings in the plant factory significantly accelerated, with increased plant height, leaf area, and stem diameter. On the 16th day after grafting, the cumulative leaf length and width fitting curves for the two cultivation methods coincided. Furthermore, it is noteworthy that the electricity consumption during the tomato seedling cultivation process, including that for controlling environmental temperature and humidity and the LED artificial supplemental lighting in the plant factory, was significantly lower. Over the two-month seedling cultivation period, the resource consumption in the greenhouse was 220% and 281% higher than in the plant factory, respectively. Statistical results also showed that the mortality rate of tomato seedlings cultivated in the artificial light plant factory was only 4.3%, much lower than the 6.5% mortality rate in the greenhouse. When the subsequent tomato plants were uniformly transplanted to the greenhouse for cultivation and their fruit weights were measured and recorded, the results indicated no significant difference in the fruit weights of tomatoes grown in the plant factory compared to those grown in the greenhouse. Therefore, experimental evidence confirms that cultivating tomato seedlings in an artificial light plant factory can significantly reduce cultivation costs, increase seedling survival rates, and not affect tomato quality.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 3","pages":"e0314808"},"PeriodicalIF":2.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Impact of feralization on evolutionary trajectories in the genomes of feral cat island populations.
IF 2.9 3区 综合性期刊
PLoS ONE Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1371/journal.pone.0320028
María Esther Nieto-Blázquez, Manuela Gómez-Suárez, Markus Pfenninger, Katrin Koch
{"title":"Correction: Impact of feralization on evolutionary trajectories in the genomes of feral cat island populations.","authors":"María Esther Nieto-Blázquez, Manuela Gómez-Suárez, Markus Pfenninger, Katrin Koch","doi":"10.1371/journal.pone.0320028","DOIUrl":"10.1371/journal.pone.0320028","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1371/journal.pone.0308724.].</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 3","pages":"e0320028"},"PeriodicalIF":2.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study.
IF 2.9 3区 综合性期刊
PLoS ONE Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1371/journal.pone.0301165
Jasper F E Crockford, Dylan X Guan, Gillian Einstein, Clive Ballard, Byron Creese, Anne Corbett, Ellie Pickering, Adam Bloomfield, Pamela Roach, Eric E Smith, Zahinoor Ismail
{"title":"Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study.","authors":"Jasper F E Crockford, Dylan X Guan, Gillian Einstein, Clive Ballard, Byron Creese, Anne Corbett, Ellie Pickering, Adam Bloomfield, Pamela Roach, Eric E Smith, Zahinoor Ismail","doi":"10.1371/journal.pone.0301165","DOIUrl":"10.1371/journal.pone.0301165","url":null,"abstract":"<p><strong>Background: </strong>Recent evidence suggests the experience of menopausal symptoms (i.e., perimenopausal symptoms) may be associated with cognitive and behavioural changes. We investigated these two relationships in a sample of postmenopausal females.</p><p><strong>Design: </strong>Cross-sectional observational study.</p><p><strong>Setting: </strong>Participant data was collected from the Canadian Platform for Research Online to Investigate Health, Quality of Life, Cognition, Behaviour, Function, and Caregiving in Aging (CAN-PROTECT) study.</p><p><strong>Participants: </strong>896 postmenopausal female participants.</p><p><strong>Methods: </strong>Menopausal symptom burden was operationalized by summing the total number of recalled perimenopausal symptoms experienced. Cognitive function was measured using the Everyday Cognition (ECog-II) Scale, with higher scores reflecting greater severity. Mild Behavioral Impairment (MBI) was measured using the Mild Behavioral Impairment Checklist (MBI-C), with higher scores reflecting greater severity. A negative-binomial regression model examined the relationship between menopausal symptom burden and cognitive function, while a zero-inflated negative binomial regression model examined the relationship between menopausal symptom burden and MBI symptoms. Models adjusted for age, years of education, age of menopausal onset, type of menopause, and hormone therapy (HT). Age of menopausal onset and use of HT in the two associations were investigated with moderation analyses.</p><p><strong>Results: </strong>Greater menopausal symptom burden was associated with higher ECog-II total scores (b [95% confidence interval (CI)] = 5.37 [2.85, 7.97]) and higher MBI-C total scores (b [95% CI] = 6.09 [2.50, 9.80]). Use of HT did not significantly associate with ECog-II total scores (b [95% CI] = -10.98 [-25.33, 6.35]), however, HT was significantly associated with lower MBI-C total scores (b [95% CI] = -26.90 [-43.35, -5.67]).</p><p><strong>Conclusions: </strong>Menopausal symptom burden is associated with poorer cognitive function and more MBI symptoms in mid- to late life. HT may help mitigate symptoms of MBI. These findings suggest that the experience of menopause may indicate susceptibility to cognitive and behavioural changes, both markers of dementia.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 3","pages":"e0301165"},"PeriodicalIF":2.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The global invasion risk of rice yellow stem borer Scirpophaga incertulas Walker (Lepidoptera:Crambidae) under current and future climate scenarios.
IF 2.9 3区 综合性期刊
PLoS ONE Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1371/journal.pone.0310234
Shravani Sanyal, A V M Subba Rao, H Timmanna, G Baradevanal, Santanu Kumar Bal, M A Sarath Chandran, P R Shashank, V K Singh, P K Ghosh
{"title":"The global invasion risk of rice yellow stem borer Scirpophaga incertulas Walker (Lepidoptera:Crambidae) under current and future climate scenarios.","authors":"Shravani Sanyal, A V M Subba Rao, H Timmanna, G Baradevanal, Santanu Kumar Bal, M A Sarath Chandran, P R Shashank, V K Singh, P K Ghosh","doi":"10.1371/journal.pone.0310234","DOIUrl":"10.1371/journal.pone.0310234","url":null,"abstract":"<p><p>Rice yellow stem borer, Scirpophaga incertulas (Walker) (Lepidoptera: Crambidae) is a serious pest, that causes significant yield loss (10-40%) to rice crop in India and other parts of the world. This study emphasizes the prediction of the potential invasion risk, distribution, and further spread of S. incertulas during current and future climate change scenarios in India and the world. The pest identity was confirmed with morphological taxonomy, and the possible habitat distribution and further spread in future climate scenarios were modelled using the MaxEnt algorithm. The climate niche for S. incertulas was also established by analyzing the correlation between the pest occurrence data of 143 locations in India and seven bioclimatic variables viz., bio01, bio02, bio03, bio05, bio12, bio13, and bio15, were chosen for predicting the distribution of S. incertulas. The model performance was good as it exhibited a strong Receiver Operating Characteristic Curve value of 0.949. Based on the Jackknife test, the Bio 13 (precipitation of the wettest month), exhibited the highest gain value and emerged as the primary abiotic factor exerting influence on the potential habitat distribution of this borer. The study demonstrated that bioclimatic variables annual mean temperature (30 °C), and annual precipitation (10-700 mm) favour its multiplication, infestation, and further spread to new areas. As the anticipated habitat range of S. incertulas is of considerable importance for researchers and other stakeholders involved in plant protection, the data generated here may be useful for researchers, policymakers, and farmers for designing better management strategies to mitigate this pest and curtail its spread to new rice growing areas in a rapidly changing global environment.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 3","pages":"e0310234"},"PeriodicalIF":2.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibiotic prescription patterns and associated symptoms in children living with HIV at Arthur Davison Children's Hospital in Ndola, Zambia.
IF 2.9 3区 综合性期刊
PLoS ONE Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1371/journal.pone.0316735
Jonathan Gwasupika, Davidson H Hamer, Victor Daka, Ephraim Chikwanda, David Mwakazanga, Ruth L Mfune, Choolwe Jacobs
{"title":"Antibiotic prescription patterns and associated symptoms in children living with HIV at Arthur Davison Children's Hospital in Ndola, Zambia.","authors":"Jonathan Gwasupika, Davidson H Hamer, Victor Daka, Ephraim Chikwanda, David Mwakazanga, Ruth L Mfune, Choolwe Jacobs","doi":"10.1371/journal.pone.0316735","DOIUrl":"10.1371/journal.pone.0316735","url":null,"abstract":"<p><strong>Background: </strong>Children with human immunodeficiency virus (HIV) infection are disproportionately susceptible to bacterial infections. There are a wide range of antibacterial agents available to manage HIV positive children with bacterial infections. However, administration of antibiotics in most children is empirical which could lead to antimicrobial resistance.</p><p><strong>Objectives: </strong>This study aimed to determine commonly prescribed antibiotics and associated symptoms in children at Arthur Davison children's hospital antiretroviral therapy clinic in Ndola, Zambia.</p><p><strong>Methods: </strong>This was a cross-sectional study that analysed the antibiotic prescribing patterns from routinely collected secondary data at Arthur Davison children's hospital. Children diagnosed with HIV before the age of 5, actively attending antiretroviral therapy clinic identified by SmartCare software and who had taken antiretroviral therapy for at least 6 months were eligible. Data were collected from files of children who met the eligibility criteria. STATA software version 16 SE (STATA Corp., College Station, Texas, USA) was used for analysis. A p-value less than 0.05 was considered statistically significant at a confidence interval of 95%.</p><p><strong>Results: </strong>From a total of 132 children included in the study, 37.9% presented with symptoms with the most common symptoms being cough (70.0%) and diarrhoea (30.0%). A larger proportion of children (62.1%) were on arbacavir/lamivudine/dolutogravr combination of antiretroviral therapy while 8.2% were on the tenoforvir alafenamide/lamivudine/dolutobravir regimen. Children who were on abacavir/lamivudine/dolutegravir regimen presented with more symptoms (48.8%) compared to those on tenofovir alafenamide/lamivudine/dolutegravir (21.0%) and tenofovir disoproxil fumarate/lamivudine/dolutegravir (18.2%) (p = 0.006). Approximately 60.0% of children presenting with symptoms were prescribed antibiotics. Co-trimoxazole was the most commonly (38.0%) prescribed, while erythromycin (2.0%) and Cephalexin (2.0%) were the least.</p><p><strong>Conclusions: </strong>Respiratory and gastrointestinal symptoms were the most common presentations suggestive of a suspected infection requiring antibiotic prescription in HIV-positive children on ART. Despite co-trimoxazole being the prophylactic drug among HIV-positive children, it was the most common antibiotic among children presenting with symptoms suggestive of an infection. This calls for the prudent use of co-trimoxazole to avoid its resistance.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 3","pages":"e0316735"},"PeriodicalIF":2.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: A Progress-driven approach to cognitive outcomes after traumatic brain injury: A study protocol for advancing equity, diversity, and inclusion through knowledge synthesis and mobilization.
IF 2.9 3区 综合性期刊
PLoS ONE Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1371/journal.pone.0319818
{"title":"Correction: A Progress-driven approach to cognitive outcomes after traumatic brain injury: A study protocol for advancing equity, diversity, and inclusion through knowledge synthesis and mobilization.","authors":"","doi":"10.1371/journal.pone.0319818","DOIUrl":"10.1371/journal.pone.0319818","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1371/journal.pone.0307418.].</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 3","pages":"e0319818"},"PeriodicalIF":2.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信