PLoS ONE最新文献

{"title":"Childhood cancer survivors' struggle for social integration after treatment a mixed-methods exploration of activity and participation.","authors":"Verena Paul, Laura Inhestern, Désirée Sigmund, Jana Winzig, Annette Sander, Stefan Rutkowski, Gabriele Escherich, Corinna Bergelt","doi":"10.1371/journal.pone.0339084","DOIUrl":"10.1371/journal.pone.0339084","url":null,"abstract":"<p><strong>Purpose: </strong>Childhood cancer presents lasting challenges beyond primary treatment, affecting multiple aspects of daily life. This mixed-methods study examines the impact of childhood cancer on activities and participation within the first five years after treatment. It mainly focuses on the interplay of factors influencing participation. Further, qualitative interviews provide contextual insights and experiential perspectives from affected families to complement the quantitative findings.</p><p><strong>Methods: </strong>The study combines qualitative interviews with 30 parents and quantitative survey data from 256 parents. The survey included self-developed items based on the International Classification of Functioning, Disability and Health (ICF). A correlation-based network analysis examined relationships among factors affecting children's activities and participation.</p><p><strong>Results: </strong>Survivors experience impairments in school activities, social interactions, and daily functioning. Network analysis highlights the interconnections among ICF-coded aspects, revealing that learning, communication, and participation in major life areas strongly influence overall activity and participation.</p><p><strong>Conclusion: </strong>While many survivors reintegrate into everyday life, hidden challenges can significantly impact their participation. This study underscores the need for a holistic, multidisciplinary approach addressing medical, educational, and psychosocial challenges, including struggles beyond visible limitations.</p><p><strong>Implications: </strong>Interventions should prioritize comprehensive support, particularly in learning, communication, and participation in school activity. Educating healthcare providers and caregivers about the interdisciplinary links between these domains is essential for a coordinated, holistic approach.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 5","pages":"e0339084"},"PeriodicalIF":2.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13155590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147856973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consumer anxiety: A scoping review and research agenda.","authors":"Mingfei Li, Shanshan Huang","doi":"10.1371/journal.pone.0349021","DOIUrl":"10.1371/journal.pone.0349021","url":null,"abstract":"<p><strong>Background: </strong>In the current vibrant and transforming era, consumers increasingly experience anxiety. Given its profound implications for consumers' psychological well-being, decision-making, and consumption behaviors, understanding consumer anxiety (CA) has become a critical issue for both scholars and practitioners. Although existing studies have investigated CA across contexts, the findings remain both limited and fragmented.</p><p><strong>Objective: </strong>To provide a comprehensive and clearer picture of CA, this scoping review synthesizes the current state of the art in CA research, develops an integrative research framework, and outlines promising avenues for future inquiry.</p><p><strong>Method: </strong>Following the Systematic Reviews and Meta-Analyses (PRISMA) guidelines, this study searched Google Scholar, ScienceDirect, EBSCO, and the Social Science Citation Index for articles. After study selection and quality assessment, 60 articles focusing on CA were identified and included in the review.</p><p><strong>Results: </strong>Current research elucidates the antecedents and consequences of CA, as well as its mediating and moderating roles in consumer studies.</p><p><strong>Conclusion: </strong>On the basis of the reviewed findings, this study discusses the research gaps and thereby proposes promising avenues for future CA research. Moreover, several valuable insights for CA management are provided for practitioners in the marketplace.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 5","pages":"e0349021"},"PeriodicalIF":2.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13155630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptom presentation, perceived causes, and help-seeking practices among adults receiving depression or anxiety care in Nepal: A qualitative study.","authors":"Nagendra P Luitel, Kriti Pudasaini, Bishnu Lamichhane, Kamal Gautam, Mark J D Jordans","doi":"10.1371/journal.pone.0347605","DOIUrl":"10.1371/journal.pone.0347605","url":null,"abstract":"<p><p>Depression and anxiety are prevalent worldwide, yet fewer than 20% of individuals in low- and middle-income countries receive appropriate care. Cultural norms play a significant role in how symptoms are expressed and how individuals seek help. In Nepal, traditional healers are often preferred over mental health specialists. This qualitative study explored how symptom presentation and perceived causes impact treatment-seeking behaviour among adults receiving care for depression or anxiety. Twenty-four participants (13 with depression, 9 with anxiety, and 2 with both conditions) were recruited from Jhapa, Chitwan, and Kailali districts through primary healthcare providers, psychosocial counselors, and mental health specialists. Individual interviews were conducted using the adapted McGill Illness Narrative Interview (MINI) to explore symptom experiences, illness narratives, perceived causes, and help-seeking patterns. Thematic analysis of the data was done using NVIVO software. Participants reported a range of emotional, cognitive, and physical symptoms including fear, anxiety, restlessness, irritability, sadness, and hopelessness. Somatic complaints like headaches, fatigue, and gastrointestinal issues were often interpreted as consequences of psychological stress. Some participants described dissociative experiences, such as detachment, amnesia, or perceptual distortions, leading to panic or self-harm. Stressors mentioned included financial hardships, bereavement, family conflicts, trauma, and culturally ingrained fears. Most participants initially sought help from biomedical providers like private clinics, hospitals, health centers, or health camps with some also consulting traditional healers. Education and caste played a significant role in treatment choices, with individuals with higher education and from higher castes more likely to seek biomedical care first. Gender and age had minimal impact. The study underscores the importance of culturally sensitive, community-based mental health programs to reduce stigma and ensure equitable access to care for depression and anxiety in Nepal.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 5","pages":"e0347605"},"PeriodicalIF":2.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13155605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep, sedentary behavior, and physical activity: A compositional data analysis of 24-hour movement behaviors and executive function in preschool children.","authors":"Ling Wang, Wanhong Luo, Yong Liu","doi":"10.1371/journal.pone.0333563","DOIUrl":"10.1371/journal.pone.0333563","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to examine the relationship between 24-h movement behaviors and executive function in preschool children.</p><p><strong>Methods: </strong>This cross-sectional study included 266 preschool children (mean age: 3-6 years). Physical activity and sedentary behavior were measured using an accelerometer (ActiGraph GT3X-BT), sleep duration was assessed using sleep logs, and executive function was evaluated using the Early Years Toolbox. Compositional data analysis was then applied to examine the associations among these variables.</p><p><strong>Results: </strong>(1) The relative distribution of 24-h movement behaviors was significantly associated with inhibitory control, cognitive flexibility, and working memory (all p < 0.001), with a model explanatory power > 10%. The explanatory power was the highest for inhibitory control (16.3%). (2) After adjusting for other movement behaviors, sedentary behavior was negatively associated with inhibitory control [γ12 = -0.11 (-0.17, -0.05), p < 0.001], cognitive flexibility [γ12 = -1.45 (-2.29, -0.61), p = 0.001], and working memory [γ12 = -0.58 (-0.97, -0.19), p = 0.004]. In contrast, sleep was positively associated with cognitive flexibility [γ11 = 1.60 (0.26, 2.94), p = 0.020]. (3) When 15 min/day of sedentary behavior was isotemporally substituted with sleep, inhibitory control scores increased by 0.003 (0.0004, 0.006), and cognitive flexibility scores increased by 0.064 (0.021,0.106); conversely, replacing sleep with sedentary behavior resulted in a significant decline.</p><p><strong>Conclusion: </strong>Reallocating time from sedentary behavior to sleep was positively correlated with executive function, particularly cognitive flexibility. However, most other isotemporal substitution pathways did not show statistically significant effects, providing an important basis for future research to focus on specific behavioral reorganization strategies.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 5","pages":"e0333563"},"PeriodicalIF":2.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13155550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on interpretable machine learning modeling and spatial prediction of cross-landform landslide disaster mechanism: A case study of Shaanxi Province.","authors":"Mingming Han, Yiwei Yang","doi":"10.1371/journal.pone.0347996","DOIUrl":"10.1371/journal.pone.0347996","url":null,"abstract":"<p><p>The differential understanding of the landslidetriggering mechanisms across various geomorphic units is vital for enhancing regional disaster prevention. This study investigates the Loess Plateau area in northern Shaanxi and the Qinba Mountain Area in southern Shaanxi as the study areas, and constructs a 15dimensional evaluation factor system covering topography, geology, vegetation, and human activities. After eliminating collinearity factors via double tests of the Pearson correlation coefficient and variance inflation factor, Bayesian optimization is used to optimize hyperparameters for CatBoost, Random Forest, LightGBM, and XGBoost, and the SHAP framework is combined to perform global attribution, single-factor dependency analysis, and interaction-effect quantification. The results demonstrate that CatBoost performs best across both geomorphic areas, achieving AUCs of 0.8307 and 0.8252 in the test sets. In northern Shaanxi, a discrete patch pattern driven by \"human-water\" coupling is observed, with population density and the topographic moisture index contributing 37.2%. In contrast, Southern Shaanxi exhibits a continuous, band-shaped distribution controlled by \"structure-topography\" is observed, and elevation and lithology dominate the model's decision-making. The SHAP-dependent map identified cross-geomorphic differences in the population density threshold of 99.83 people/km2, the slope threshold of 2.21° in northern Shaanxi, and the elevation threshold of 1194.73m in southern Shaanxi. Furthermore, the interaction network revealed an antagonistic effect of DEM and POP in northern Shaanxi and of DEM and LULC in southern Shaanxi. The framework proposed a quantitative, explainable basis for differentiated disaster prevention strategies in this research.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 5","pages":"e0347996"},"PeriodicalIF":2.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13155597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Swiss public attitudes to human cryopreservation.","authors":"José Paulo Rodrigues Dos Santos, Nadia X Montazeri, Tijana Perović, Emil F Kendziorra","doi":"10.1371/journal.pone.0332005","DOIUrl":"10.1371/journal.pone.0332005","url":null,"abstract":"<p><p>Cryopreservation, or cryonics, is an experimental procedure that preserves individuals at cryogenic temperatures after legal death in the hope of future revival. Although Switzerland hosts the Schengen Area's first dedicated whole-body human cryopreservation facility, public sentiment toward the practice has remained largely unexamined. This exploratory survey of 249 Swiss adults assessed awareness, ethical views, and openness to cryopreservation. Results show broad support for individual autonomy, with most respondents endorsing the right to choose cryopreservation when performed to high medical standards (86.7%) and not supporting legal restrictions (83.5%). While personal interest was in the minority, nearly one in five respondents (20.1%) reported active interest or intent to sign up. Openness to cryopreservation appears driven more by values such as life-extension preference and prior exposure than by demographics. These findings provide the first empirical snapshot of Swiss public opinion on cryopreservation, highlighting a largely permissive public stance and suggesting considerable engagement with the topic.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 5","pages":"e0332005"},"PeriodicalIF":2.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13155587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic inequalities and the COVID-19 pandemic in France: Territorial analyzes based on epidemic wave and metropolitan area.","authors":"Luka Canton, Pierre Schalkwijk, Jordi Landier, Stanislas Rebaudet, Emilie Mosnier, Pascal Handschumacher, Stève Nauleau, Philippe Malfait, Ludivine Launay, Cyrille Delpierre, Michelle Kelly-Irving, Sabira Smaili, Stephanie Vandentorren, Jean Gaudart","doi":"10.1371/journal.pone.0348201","DOIUrl":"10.1371/journal.pone.0348201","url":null,"abstract":"<p><strong>Background: </strong>Previous studies have highlighted the relationship between socioeconomic inequalities and the general population's risk of contracting or dying from COVID-19 during the 2020-2023 pandemic. In France, socioeconomic inequalities vary across metropolitan areas; few studies have investigated whether this variation explains the spatial disparities observed in COVID-19 incidence and testing rates during the pandemic. We examined the relationship between socioeconomic profiles and these two rates across all 22 metropolitan areas in France for eight of the country's nine epidemic waves.</p><p><strong>Methods: </strong>For each metropolitan area, we used socioeconomic variables from census data to define socioeconomic profiles through principal component clustering. We then used spatialized generalised additive mixed models to analyze associations between these profiles and both testing and incidence rates, for each epidemic wave from July 2020 to March 2023. Finally, we performed meta-regressions to study the distribution of testing and incidence rate ratios among the various socioeconomically deprived and privileged profiles within each of the 22 metropolitan areas, according to COVID-19 vaccination rate.</p><p><strong>Results: </strong>Testing rates were lower in socioeconomically deprived metropolitan areas than in privileged ones, except during wave 4 (July-October-2021), when testing rates were more similar. Incidence rates were higher in deprived areas (waves 2-4, July-2020 to October-2021), but this pattern reversed between waves 6-9 (March-2022 to March-2023). Meta-regressions indicated that high vaccination coverage was associated with a narrower gap in testing between deprived and privileged areas. Moreover, for each metropolitan area, the higher the level of deprivation in a zone within the deprived profile, the greater the deprived-privileged gap in under-testing.</p><p><strong>Conclusions: </strong>The impact of socioeconomic inequalities on testing and incidence patterns during the COVID-19 pandemic in each metropolitan area in France was driven by the most deprived zones; this impact varied across epidemic waves. Higher vaccination rates and government health measures (lockdowns, mandatory health pass) may have reduced this variation.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 5","pages":"e0348201"},"PeriodicalIF":2.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13155628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuromedin U mediates left atrial pressure-induced diuresis in the anaesthetised pig.","authors":"Vincent Healy, Therese Ruane O'Hora, Eric Lucking, Gerard O'Donoghue, Farouk Markos","doi":"10.1371/journal.pone.0348773","DOIUrl":"10.1371/journal.pone.0348773","url":null,"abstract":"<p><p>Finding a potential biomarker for elevated left atrial pressure would be clinically useful as a diagnostic for pre-heart failure. Therefore, an investigation into whether the protein neuromedin U (NMU), which is significantly elevated in heart failure patients, mediates a classical diuresis that results from a sustained increase in left atrial pressure was conducted in the anaesthetized pig. Left atrial pressure was increased a little above 15 mmHg for 30 minutes in 8 chloralose anaesthetised female pigs. There was a significant increase in circulating NMU and urine flow rate, which surprisingly occurred without an accompanying natriuresis; both the serum NMU increase and the diuresis did not occur when the procedure was repeated post-vagal section. There was also a significant increase in glomerular filtration rate during the diuresis, which indicates a likely direct renal effect. The results show that NMU could be the mediator of the historic diuresis induced by an increased left atrial pressure. Future work to assess NMU levels in humans in pre-heart failure would be required to confirm NMU's potential usefulness as a diagnostic.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 5","pages":"e0348773"},"PeriodicalIF":2.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13155543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variants in the DNAH11 gene responsible for primary ciliary dyskinesia or probably atypical primary ciliary dyskinesia presenting left-right asymmetry disorder.","authors":"Kai Zhao, Lamei Yuan, Ying Xiong, Hong Xia, Sheng Deng, Ming Chen, Yunjie Liao, Jiangang Wang, Hao Deng","doi":"10.1371/journal.pone.0348352","DOIUrl":"https://doi.org/10.1371/journal.pone.0348352","url":null,"abstract":"<p><p>Primary ciliary dyskinesia (PCD) is a rare multi-system cilia-related disorder, and approximately 50% of individuals with PCD exhibit left-right asymmetry disorder. The dynein axonemal heavy chain 11 gene (DNAH11) pathogenic variants are responsible for primary ciliary dyskinesia 7, with or without left-right asymmetry disorder. This study aimed to detect the pathogenic variants in three unrelated patients diagnosed with PCD or left-right asymmetry disorder based on the clinical and imaging examinations. Whole exome sequencing, Sanger sequencing, and comprehensive bioinformatics analyses were performed. Seven DNAH11 heterozygous variants, which involved evolutionarily conserved residues and were predicted to exert deleterious effects, reduce protein stability, change protein conformation, and affect non-covalent residue's interactions, were identified as potential pathogenic factors responsible for these patients, respectively. In patient 1, three variants in compound heterozygotes, c.[3541A > G];[4334G > A;12428T > C] (p.[(Ser1181Gly)];[(Arg1445Gln;Met4143Thr)]), were confirmed. In patient 2, two variants in potential compound heterozygotes, c.2912A > G(;)7980A > T (p.(Asp971Gly)(;)(Gln2660His)), were detected. In patient 3, two variants in compound heterozygotes, c.[845T > C];[11402C > G] (p.[(Met282Thr)];[(Pro3801Arg)]), were confirmed. The phenotypes observed in these patients are consistent with typical/probably atypical PCD or DNAH11-associated ciliopathy, although functional validation is needed to confirm variant pathogenicity. These findings expand the phenotypic spectrum of DNAH11 variants and may facilitate more accurate genetic diagnosis and counseling.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 5","pages":"e0348352"},"PeriodicalIF":2.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147856566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using fractal model and factor analysis for FACA modeling and its application in deep mineral prediction.","authors":"Feilong Qin, Hongjin Zhu, Yu Feng, ShiCheng Yu","doi":"10.1371/journal.pone.0348494","DOIUrl":"10.1371/journal.pone.0348494","url":null,"abstract":"<p><strong>Objective: </strong>This paper designs a FACA model for deep mineral prediction in actual mining areas.</p><p><strong>Method: </strong>The spatial distribution of geochemical anomalies was consistent with the concentration--area (C-A), this paper established a C-A model for geochemical anomaly extraction. Based on mineral resources formed by multiple element combinations, factor analysis (FA) was used to obtain the different combinations and comprehensive information of elements. On this basis, a new FACA model was designed for mineral prediction using the FA and C-A.</p><p><strong>Results: </strong>The proposed FACA model was applied to mineral prediction in the Jiguanzui copper-gold mining area in China. The elements in the study area were divided into four combinations. The thresholds of single element and element combination anomalies were identified. Through diagnostic testing, the abnormal distributions of geochemical elements were consistent with their theoretical distributions, and the comprehensive abnormal distribution area of elements was consistent with the distribution of the actual ore bodies, demonstrating that the designed FACA algorithm of this paper was reasonable.</p><p><strong>Conclusions: </strong>A new blind ore body in the study area is predicted by using FACA model, positioned at a depth ranging from approximately 1120m to 1150m below ground, between drill holes ZK02618 and KZK23. These findings hold significant implications for mineral exploration efforts.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"21 5","pages":"e0348494"},"PeriodicalIF":2.6,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13155623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147856599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}