PLoS ONE最新文献

{"title":"Spatial factors affecting young females' disaster exposure in municipalities facing population decline.","authors":"Jun Sakamoto","doi":"10.1371/journal.pone.0334706","DOIUrl":"10.1371/journal.pone.0334706","url":null,"abstract":"<p><p>Understanding and reducing the risk of natural disasters is crucial for maintaining the economy and society. Since Japan is a disaster-prone country and the most advanced nation in the world regarding aging and population decline, it necessitates a natural disaster risk analysis that considers both challenges. This paper represents the first study to explore the risk of natural disasters, specifically for young females exposed to four types of events: floods, tsunamis, storm surges, and sediment disasters, particularly in municipalities at risk of vanishing. We identified municipalities with a high proportion of young females exposed to these natural disasters and examined them from a geographical perspective. Utilizing a spatial regression model, we statistically analyzed the factors influencing the proportion of the exposed population. The result showed that young females exposed to flooding tend to the areas with a higher proportion of habitable land, inland regions, and locations abundant in rivers and lakes. Conversely, young females affected by tsunamis tend to be in coastal areas with few buildings. Additionally, those exposed to storm surges are often in regions characterized by features such as rice fields and other facilities. In the case of landslides, young females tend to reside in areas where habitable land is scarce, such as coastal regions. Our findings suggest that municipalities with a risk of citywide flooding or storm surge should enhance countermeasures, such as implementing building regulations in high-hazard residential areas. Additionally, it recommends that municipalities with a risk of tsunami or sediment should relocate hazardous housing.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 10","pages":"e0334706"},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12533900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of heavy metal contamination in topsoils across land use types within the Manghe River watershed in South Taihang and its source attribution.","authors":"Xiaoqiang Wan, Chengyu Wang, Quanlai Ma, Chongke Yang, Jizhou Zhang, Yingtao Shang","doi":"10.1371/journal.pone.0335016","DOIUrl":"10.1371/journal.pone.0335016","url":null,"abstract":"<p><p>To investigate the characteristics of soil heavy metal pollution in the Manghe River watershed, a typical industrial and mining complex area in the Yellow River Basin, concentrations of Hg, Cr, Cu, Ni, Pb, Zn, Cd, and pH were measured in 121 topsoil samples (0-20 cm) collected from the study area. Geostatistical methods were employed to analyze the spatial distribution patterns of heavy metals. The pollution status was assessed using the pollution load index (PLI), while correlation analysis, principal component analysis (PCA), and a positive matrix factorization (PMF) model were applied to identify the sources of heavy metals. The results indicated that: (1) The concentrations of Hg, As, Ni, Cu, Pb, Zn, and Cd exceeded their respective background values, with Hg, Pb and Cd reaching 3.52, 4.85, and 46.4 times of the background levels, respectively.(2) Different elements exhibited distinct spatial distribution and diffusion patterns, revealing their respective sources and influencing factors. (3) The overall PLI was 0.785, reflecting a mild pollution level across the region, while industrial and mining lands exhibited severe pollution (PLI = 4.3). The relative contribution of each heavy metal to the pollution load was ranked as follows: Cd (30.35)> Pb (4.76)> Hg (3.62)> Zn (2.18)> As (1.77)> Cu (1.53). (4) Principal component analysis categorized the sources of heavy metals into anthropogenic activities and natural origins. Further analysis using the PMF model delineated four specific sources: coal combustion (10.87%), natural and agricultural contributions (27.37%), transportation and agricultural actives (26.81%), and industrial emissions (34.95%). Finally, the study identified the following feasible strategies for controlling heavy metal pollution: blocking and remediating industrial pollution sources; treating agricultural non-point source pollution through biological methods; and substituting traditional transportation sources with new energy alternatives. This research could support decision-making processes related to the prevention and control of heavy metal pollution in the study area, as well as regional sustainable development.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 10","pages":"e0335016"},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12533886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of ABCG2 421G>T (rs2231142) Polymorphism with rosuvastatin induced adverse effects in dyslipidemic patients: Implication for personalized medicine.","authors":"Mahjabeen Sharif, Kulsoom Farhat, Mudassar Noor, Ahsan Maqbool Ahmad, Dilshad Ahmed Khan, Raja Kamran Afzal, Muhammad Bilal Siddique","doi":"10.1371/journal.pone.0334600","DOIUrl":"10.1371/journal.pone.0334600","url":null,"abstract":"<p><p>Statins are considered as the first line drugs for the treatment of hyperlipidemia. Despite proven efficacy of rosuvastatin, inter-individual variations in plasma rosuvastatin levels have been documented in various studies which causes variable response to statin tolerance. This study aims to evaluate the possible association of ABCG2 421 G > T (rs2231142) polymorphism with inter-individual variations in plasma rosuvastatin levels which potentially increases the rosuvastatin related adverse effects. This quasi experimental study was carried out from June 2022 till December 2023 in two tertiary care hospitals of Pakistan. Hyperlipidemic patients with low density lipoprotein more than 130 mg/dl were enrolled through non-probability purposive sampling. All the enrolled patients were treated with rosuvastatin 10 mg once daily for 12 weeks. Fasting lipid profile, serum creatine phosphokinase, liver and renal function tests were measured at the start of study and after 12 weeks of intervention with rosuvastatin. Blood samples were also collected for genotyping and determination of plasma rosuvastatin levels. Frequency of ABCG2 421 G > T polymorphism for wild type GG, heterozygous mutant GT and homozygous mutant TT genotypes were 54.5, 36.2 and 9.3% respectively. Minor allele frequency was 0.27. Patients with TT and GT genotypes have significantly raised plasma levels of rosuvastatin with mean value of 30.23 ± 4.8 ng/mL and 22.35 ± 5.1 ng/mL respectively as compared to wild GG genotypes 13.95 ± 8.9 ng/mL (p=<0.001). Frequency of myopathy, hepatotoxicity and nephrotoxicity in study population was 5.3, 3.2 and 4.8% respectively. All the genetic models including co-dominant model GT (OR= 5.45, 95% CI: 3.09-9.62, p= < 0.0001), TT (OR= 88.51, 95% CI: 24.84-315.44), dominant model (OR= 8.45, 95% CI: 4.91-14.52, p= < 0.0001), recessive model (OR=37.29, 95%CI 11.06-125.78, p < 0.001), over-dominant model, (OR= 2.26, 95% CI: 1.42-3.60, p= < 0.0001) showed significant association with rosuvastatin adverse effects. It is inferred that patients having T variant allele is associated with higher plasma rosuvastatin concentration and increased the risk of development of adverse effects compared with G allele carriers. It is therefore suggested that genetic profiling may be done for dose tailoring to minimize the statin intolerance.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 10","pages":"e0334600"},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12533910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Association between socioeconomic background and cancer: An ecological study using cancer registry and various community socioeconomic status indicators in Kanagawa, Japan.","authors":"Satoru Kanda, Kaname Watanabe, Sho Nakamura, Hiroto Narimatsu","doi":"10.1371/journal.pone.0334930","DOIUrl":"10.1371/journal.pone.0334930","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1371/journal.pone.0326895.].</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 10","pages":"e0334930"},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12533835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malaria in travelers and local populations: Comprehensive study of incidence patterns and origin-based classification in Saudi Arabia.","authors":"Basmah Alharbi, Mawahib Ahmed","doi":"10.1371/journal.pone.0335137","DOIUrl":"10.1371/journal.pone.0335137","url":null,"abstract":"<p><strong>Background: </strong>Malaria continues to pose a significant public health threat in the Kingdom of Saudi Arabia (KSA), despite ongoing control efforts. Most malaria cases in the KSA are associated with travelers arriving from malaria-endemic regions. The rationale for studying malaria in the KSA stems from the country's goal to eliminate the disease and address the increased risk of imported cases, which is heightened by substantial migration and religious tourism.</p><p><strong>Methods: </strong>This study aimed to assess the origins of malaria cases, the relative contribution of the different Plasmodium species involved, and the incidence rates across different age groups in the KSA. The Ministry of Health collected data on malaria cases in 13 administrative regions from January 2022 to December 2023. The chi-square test was used to analyze the data and determine the overall parameters and the rate of slide positivity.</p><p><strong>Results: </strong>The findings indicated that \"imported\" malaria cases were the predominant type of disease in the KSA. Out of 1,453,451 febrile cases examined, 0.7% (10,779) were positive across the 13 regions. In 2022, 688,629 cases were examined, with 0.9% (6,460) being positive. In 2023, 764,822 cases were examined, with 0.6% (4,319) being positive. Among these regions, Jazan exhibited the highest incidence rates (59%), followed by Makkah (20%), with a statistically significant difference (P = 0.046) between the regions. Malaria incidence was higher in patients aged ≥15 years. This study found significant variations (P = 0.002) in malaria incidence rates among different Plasmodium species. Plasmodium falciparum exhibited the highest rate at 63.5%, followed by P. vivax-P. ovale at 33%, P. malariae at 0.5%, and mixed infections where more than one species is involved at 3%.</p><p><strong>Conclusion: </strong>During the study period, imported malaria was the major type of malaria, especially in the Jazan region and Makkah. The highest incidence was caused by P. falciparum. These findings indicate the need for targeted interventions and public health strategies to mitigate the \"imported\" malaria burden, particularly among travelers.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 10","pages":"e0335137"},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12533899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The interplay between social dominance and decision-making under expected and unexpected uncertainty: Evidence from event-related potentials.","authors":"Saeedeh Khosravi, Lydia Kogler, Reza Khosrowabadi, Touraj Hashemi, Birgit Derntl, Soomaayeh Heysieattalab","doi":"10.1371/journal.pone.0334065","DOIUrl":"10.1371/journal.pone.0334065","url":null,"abstract":"<p><p>Decision-making is a fundamental aspect of human behavior, especially in uncertain situations where social interactions play a significant role. Social dominance, which involves power dynamics within groups, holds the potential to shape decision-making. Individuals' expectations and certainty about outcomes are crucial for monitoring their performance in social dominance situations. However, the impact of expected and unexpected uncertainty on decision-making in social dominance contexts remains unclear. This study aimed to unravel the neural and behavioral patterns associated with decision-making across varying social dominance levels under conditions of uncertainty. Researchers investigated this by analyzing brain activity in 51 students. Participants were presented with both positive and negative feedback under conditions of both expectation and uncertainty, while their brain activity was recorded using electroencephalography (EEG). Specifically, we investigated the properties of key neural correlates of feedback processing, including feedback-related negativity (FRN), and P3 components of event-related potential (ERP), and reward prediction error (RPE) signals. The results revealed that the low-dominance group exhibited a larger FRN amplitude than the high-dominance group. Also, unexpected-uncertain negative feedback elicits a stronger FRN amplitude than other conditions. P3 amplitude was larger for high-dominance compared to low-dominance individuals. Additionally, P3 amplitude varied by feedback valence and condition, with larger amplitudes for positive feedback and unexpected-uncertain conditions. In FRN wave difference, the high-dominance individuals exhibited more negative amplitude in unexpected-uncertain conditions. This reveals distinct neural responses to uncertainty and feedback between individuals with high and low dominance, suggesting that social hierarchy modulates brain mechanisms underlying decision-making and reward processing.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 10","pages":"e0334065"},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12533924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Numerical study of flow and heat transfer in circular T-shaped junction of different cross-sections.","authors":"Eman Muhammad, Humayoun Shahid, Sheheryar Mohsin Qureshi, Muhammad Babar Ramzan","doi":"10.1371/journal.pone.0334236","DOIUrl":"10.1371/journal.pone.0334236","url":null,"abstract":"<p><p>This study investigates fluid flow and convective heat transfer within a smooth, two-dimensional T-shaped junction using a numerical approach. Simulations were conducted by varying the volumetric flow rate ratio r (0.25, 0.5, 0.75, and 1), the Reynolds number Re (500 to 2500), the Prandtl number Pr (1), and the cross-sectional width ratio w (0.5 to 2.5) of the outlet. The fluid dynamics were solved using the vorticity-stream function formulation with a compact upwind finite difference scheme and the Implicit-Explicit (IMEX) method, implemented in MATLAB. Flow behavior was analyzed through streamline and isotherm contours, while local and average Nusselt numbers were computed along the junction walls. The results show that lower r values lead to stronger vortex formation and asymmetry in the flow and temperature fields, while r = 1 yields symmetric and stable patterns. Increasing Re enhances heat transfer and transitions the flow toward unsteady regimes. Similarly, wider outlet configurations (higher w) promote recirculation and thermal mixing. This study provides valuable insights into how inlet flow, outlet shape, and fluid characteristics interact to influence heat transfer and flow behavior in a smooth T-shaped junction. It also provides insights that can help improve the design of heat exchangers, microfluidic systems, and industrial piping.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 10","pages":"e0334236"},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12534075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Possessing potential weapons (still) heightens anger perception: Replicating and extending a test of error management theory.","authors":"Cody Moser, Richard Ellk, Ayonna Jones, Colin Holbrook","doi":"10.1371/journal.pone.0326446","DOIUrl":"10.1371/journal.pone.0326446","url":null,"abstract":"<p><p>Error Management Theory (EMT) hypothesizes that humans are functionally biased to err on the side of the least costly mistake when making judgments under uncertainty. Applying EMT to emotion perception, previous studies found that people perceive individuals holding everyday objects with potentially lethal affordances to be both higher in state anger and more anger-prone, relative to individuals holding control objects. Here, we conduct a direct replication of one such study examining these effects [13] and exploratorily test whether friends of an individual possessing a potentially lethal tool are also perceived as angrier-and hence more dangerous-in a \"reverse-halo\" effect. Participants (N = 476) were presented an image of an individual depicted as an avid cook and either holding or near a conventional kitchen knife, then asked to rate their emotional states and trait dispositions. Participants were next presented with an image of a second individual framed as a close friend of the cooking enthusiast and asked to assess their emotional states and dispositions. The results replicated prior findings that individuals depicted holding everyday objects with incidentally lethal affordances are perceived as angrier, more prone to anger, and more socially unpleasant. However, we did not find evidence for a \"reverse-halo\" effect extending to friends. Instead, all of the state and trait emotion ratings of the two individuals were significantly correlated, consistent with an inference (orthogonal to error management motivations) of homophilic similarity in the affective profiles of friends. These results are discussed as they inform prior EMT research and motivate further study of the determinants of emotion perception.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 10","pages":"e0326446"},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12533867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New bridging eco-acoustic indices inspired by deep neural networks for fine-grained bird vocalization recognition across diurnal cycles.","authors":"Lianglian Gu, Wei Li, Guangzhi Di, Danju Lv, Yan Zhang, Yueyun Yu, Ziqian Wang","doi":"10.1371/journal.pone.0328098","DOIUrl":"10.1371/journal.pone.0328098","url":null,"abstract":"<p><p>Revealing difference in bird vocalization changes from the perspectives of song recognition and acoustic indices has become a hot topic and challenge in recent ecological landscape research. This paper proposes a fine-grained (Dawn, noon, night) bird vocalization recognition framework based on a two-layer deep network to identify the same species' bird vocalization at different times of the day. Additionally, a new acoustic index method, the Log-Mel Acoustic Complexity Index (Log-Mel ACI), is introduced to explore the differences in bird vocalization of the same species throughout the day. The results of two-layer deep network showed significant separability of the bird vocalization of the same species at dawn, noon, and night based on Log-Mel spectrum. Furthermore, it was found that the improved ACI based on Log-Mel exhibits better circadian rhythmic performance than the traditional ACI, being highest at dawn, followed by night, and lowest at noon. These findings demonstrate that Log-Mel is effective in both deep network recognition and ACI calculation.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 10","pages":"e0328098"},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12533891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-driven 3D CT imaging prediction model for improving preoperative detection of visceral pleural invasion in early-stage lung cancer.","authors":"Wakako Nagase, Kazuharu Harada, Yujin Kudo, Jun Matsubayashi, Ikki Takada, Jinho Park, Kotaro Murakami, Tatsuo Ohira, Toshitaka Nagao, Masataka Taguri, Norihiko Ikeda","doi":"10.1371/journal.pone.0332956","DOIUrl":"10.1371/journal.pone.0332956","url":null,"abstract":"<p><p>Visceral pleural invasion (VPI) is a critical prognostic factor in early-stage non-small-cell lung cancer (NSCLC), significantly affecting patient outcomes. Conventional computed tomography (CT) often fails to diagnose VPI accurately. This retrospective case-control study evaluated the efficacy of artificial intelligence (AI)-assisted three-dimensional (3D) CT imaging for predicting VPI in 556 patients with clinical stage 0-I NSCLC who underwent complete surgical resection. Patients with tumors > 4 cm, those not adjacent to the pleural surface, or with unsuitable CT scans were excluded. Radiological features were analyzed using AI software capable of 3D imaging and characterization of pulmonary nodules (Synapse Vincent System, Fujifilm Corporation, Japan). The dataset was divided into training (n = 408) and test (n = 148) cohorts. Stability selection identified \"Solid nodule\" and \"Pleural contact\" as key predictors. Logistic regression analysis using these features developed prediction models for VPI. Receiver operating characteristic analysis showed that the area under the curve of the derived model was 0.831 and 0.782 in the training and test cohorts, respectively. The sensitivity and specificity were 0.739 and 0.657 in the test cohorts. These findings suggest that AI-enhanced 3D CT imaging significantly improved the preoperative prediction of VPI in NSCLC, supporting AI's integration into diagnostic processes.</p>","PeriodicalId":20189,"journal":{"name":"PLoS ONE","volume":"20 10","pages":"e0332956"},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12533904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}