Photochemistry and Photobiology最新文献_第5页

Photodynamic therapy of cancer-associated infections. 癌症相关感染的光动力治疗。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2024-12-31 DOI: 10.1111/php.14038

Giulia Kassab, Juan Chen, Gang Zheng

引用次数: 0

From femtoseconds to minutes: Spectroscopic study of optically induced thermal diffusion in aqueous solution of rhodamine B. 从飞秒到分：罗丹明B水溶液中光诱导热扩散的光谱研究。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2024-12-31 DOI: 10.1111/php.14042

René A Nome, Alexandre H Oliveira

{"title":"From femtoseconds to minutes: Spectroscopic study of optically induced thermal diffusion in aqueous solution of rhodamine B.","authors":"René A Nome, Alexandre H Oliveira","doi":"10.1111/php.14042","DOIUrl":"https://doi.org/10.1111/php.14042","url":null,"abstract":"Given that non-equilibrium molecular motion in thermal gradients is influenced by both solute and solvent, the application of spectroscopic methods that probe each component in a binary mixture can provide insights into the molecular mechanisms of thermal diffusion for a large class of systems. In the present work, we use an all-optical setup whereby near-infrared excitation of the solvent leads to a steady-state thermal gradient in solution, followed by characterization of the non-equilibrium system with electronic spectroscopy, imaging, and intensity. Using rhodamine B in water as a case study, we perform measurements as a function of solute concentration, temperature, wavelength, time, near-infrared laser power, visible excitation wavelength, and isotope effect. We find that spectroscopic excitation of solute and solvent as a function of temperature can be used to understand the thermal diffusion signal. Non-equilibrium molecular dynamics simulations and analysis of infrared spectra and heat diffusion, and stochastic dynamics simulations of the coupled Brownian/spectroscopic non-equilibrium dynamics. The stochastic/spectroscopic model shows how near-infrared excitation of the solvent influences lifetime dynamics on the picosecond timescale as well as Brownian dynamics in real time. Overall, the results presented here exemplify how spectroscopic probing of solute and solvent can be useful for understanding molecular mechanisms of optically induced thermal diffusion in aqueous solution of rhodamine B.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Light responses during early day phases of CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) and PSEUDO-RESPONSE REGULATOR (PRR) homologous genes in the moss Physcomitrium patens. 苔藓中昼夜节律时钟相关1 （CCA1）和伪反应调节因子（PRR）同源基因在早期阶段的光响应

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2024-12-27 DOI: 10.1111/php.14047

Katsuhiro Chiso, Takafumi Yamashino, Ryo Suzuki, Tanja Gans, Silvia Trogu, Jon Hughes, Setsuyuki Aoki

{"title":"Light responses during early day phases of CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) and PSEUDO-RESPONSE REGULATOR (PRR) homologous genes in the moss Physcomitrium patens.","authors":"Katsuhiro Chiso, Takafumi Yamashino, Ryo Suzuki, Tanja Gans, Silvia Trogu, Jon Hughes, Setsuyuki Aoki","doi":"10.1111/php.14047","DOIUrl":"https://doi.org/10.1111/php.14047","url":null,"abstract":"Circadian clocks facilitate organisms' adaptation to the day-night environmental cycle. Some of the component genes of the clocks (\"clock genes\") respond directly to changes in ambient light, supposedly allowing the clocks to synchronize to and/or oscillate robustly in the environmental cycle. In the dicotyledonous model plant Arabidopsis thaliana, the clock genes CIRCADIAN CLOCK ASSOCIATED 1 (CCA1), LATE ELONGATED HYPOCOTYL (LHY) and PSEUDO-RESPONSE REGULATOR 9 (PRR9) show transient expression in response to the morning light. Here we studied light responses of CCA1a/CCA1b and PRR2, homologous genes to CCA1/LHY and PRR9, respectively, in the moss Physcomitrium patens. We found that light of different wavelengths induced PRR2 while they repressed CCA1a/CCA1b. A disruption strain lacking all phytochrome genes lost PRR2 induction, but still maintained CCA1a/CCA1b repression. The remaining light repression of CCA1a/CCA1b was impaired by the photosynthesis inhibitor 3-(3,4-dichlorophenyl)-1,1-dimethylurea. Probably therefore, a phytochrome signaling induces PRR2, whereas a photosynthesis-mediated signaling represses CCA1a/CCA1b. Conservation and divergence in the clock gene responses between P. patens and A. thaliana are discussed.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heavy atom effects on synthetic pyranoanthocyanin analogues. 重原子对合成吡喃花青素类似物的影响。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2024-12-26 DOI: 10.1111/php.14058

Lucas M O S Martins, Gustavo T M Silva, Lucas F S Hess, Alexandre B Barbosa, Claudia Turro, Mauricio S Baptista, Frank H Quina

{"title":"Heavy atom effects on synthetic pyranoanthocyanin analogues.","authors":"Lucas M O S Martins, Gustavo T M Silva, Lucas F S Hess, Alexandre B Barbosa, Claudia Turro, Mauricio S Baptista, Frank H Quina","doi":"10.1111/php.14058","DOIUrl":"https://doi.org/10.1111/php.14058","url":null,"abstract":"Pyranoflavylium cations are synthetic analogues of pyranoanthocyanins, the much more color-stable compounds that are formed spontaneously from grape anthocyanins during the maturation of red wines. In the present work, our studies of the photophysical properties of pyranoanthocyanin analogues are extended to include nine pyranoflavylium cations substituted with one or two bromo and/or iodo heavy atoms. The room temperature fluorescence, 77 K fluorescence and phosphorescence, triplet formation in solution, and sensitized singlet oxygen formation, with excited state acidity suppressed by the addition of trifluoroacetic acid, are compared to those of similar pyranoflavylium cations that do not contain a heavy atom. Heavy atom effects on the photophysics of the S1 state of pyranoflavylium cations are found to be relatively small, which is attributed to the nodal properties of the orbitals involved, which prevent effective mixing of the spin-orbit coupling on the heavy atoms into the excited singlet state, S1, of the pyranoflavylium chromophore. Heavy atom effects on the phosphorescence of these heavy atom-substituted pyranoflavylium cations at 77 K are somewhat larger, consistent with a spin-orbit coupling-induced increase in the radiative rate constant for phosphorescence, as are the triplet-sensitized singlet oxygen formation quantum yields in fluid solution.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

UV-A photodegradation of vanillin in aqueous solutions: Direct photolysis and photosensitized degradation. 水溶液中香兰素的UV-A光降解：直接光解和光敏降解。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2024-12-22 DOI: 10.1111/php.14051

Heryerli Fernandez, Leo Niederst, Cécile Joyeux, Xavier Allonas, Carolina Lorente

{"title":"UV-A photodegradation of vanillin in aqueous solutions: Direct photolysis and photosensitized degradation.","authors":"Heryerli Fernandez, Leo Niederst, Cécile Joyeux, Xavier Allonas, Carolina Lorente","doi":"10.1111/php.14051","DOIUrl":"https://doi.org/10.1111/php.14051","url":null,"abstract":"Phototoxicity of skin due to the application of skincare products or fragrances is increasing from day to day, since a lot of natural extracts, with low or no toxicity in the dark, are being used in the skin exposed to solar radiation. In particular, the use of 4-hydroxy-3-methoxy benzaldehyde, known as vanillin, in the pharmaceutical, food, and cosmetic industries has increased in the last years. This compound is generally considered as safe for humans, and it has been used in a wide range of applications. Significant beneficial properties, such as antioxidant, anticancer, antimicrobial, among others, have been described for vanillin, along with low toxicity. However, although vanillin is used as an ingredient in cosmetic formulations that are applied to the skin, there are few studies on the photochemistry of vanillin degradation. The degradation of vanillin in aqueous solutions exposed to UV-A radiation (365 nm), both by direct absorption and by means of a photosensitized mechanism, was evaluated in different experimental conditions. On the bases of the experimental results, direct photodegradation of vanillin seems unlikely; however, photosensitized degradation of vanillin was observed in the presence of pterin, and vanillin dimers (6,6-dihydroxy-5,5- dimethoxy-[1,1-biphenyl]-3,3-dicarboxaldehyde) were detected as products. The mechanistic analysis indicates that the long-lived pterin triplet excited state is responsible of vanillin degradation, while the contribution of reactive oxygen species, such as superoxide anion, hydrogen peroxide, or singlet oxygen, is negligible. The thermodynamic feasibility of the potential reactions involved in the degradation mechanism was evaluated with the Rehm-Weller equation. Considering both the thermodynamic and kinetic evidence, we proposed a mechanism for the photosensitized degradation of vanillin.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photodynamic therapy as a potential approach for preventing fungal spread associated with the use of endotracheal tubes. 光动力疗法作为一种潜在的方法来防止真菌传播与使用气管内管。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2024-12-22 DOI: 10.1111/php.14054

Gabriel Grube Dos Santos, Amanda Cristina Zangirolami, Maria Luiza Ferreira Vicente, Vanderlei Salvador Bagnato, Kate Cristina Blanco

{"title":"Photodynamic therapy as a potential approach for preventing fungal spread associated with the use of endotracheal tubes.","authors":"Gabriel Grube Dos Santos, Amanda Cristina Zangirolami, Maria Luiza Ferreira Vicente, Vanderlei Salvador Bagnato, Kate Cristina Blanco","doi":"10.1111/php.14054","DOIUrl":"https://doi.org/10.1111/php.14054","url":null,"abstract":"Fungal infections related to biofilm formation on medical devices, such as endotracheal tubes (ETTs), pose significant health risks, especially during intubation procedures where fungi like Candida spp. can migrate into the lower respiratory tract. This study explores the use of Photodynamic Therapy (PDT) to prevent fungal cell migration from ETT surfaces to lungs, focusing on the role of curcumin as a photosensitizer. ETTs were coated with varying concentrations of curcumin, and biofilm formation was measured after applying PDT with a 50 J/cm2 irradiation dose. The study found that ETTs functionalized with a one-third concentration of CUR reduced biofilm formation by 1.78 Log, significantly lowering microbial load and potentially decreasing hospital-acquired infections. Confocal fluorescence microscopy confirmed that PDT damaged the biofilm's extracellular matrix and caused detachment of dead fungal cells. Moreover, the fluorescence analysis reveals the photodegradation behavior of the photosensitizer within the tube, providing critical insights into its stability and durability, which are essential for evaluating the long-term applicability of these tubes in clinical settings. These results suggest PDT as a promising strategy to reduce fungal infections in high-risk patients, offering potential for future clinical application in preventing device-associated infections.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aggregation assisted enhancement of singlet oxygen generation by 4-ethynylphenyl substituted porphyrin photosensitizer for photodynamic therapy. 聚集体辅助增强4-乙基苯基取代卟啉光敏剂光动力治疗的单线态氧生成。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2024-12-20 DOI: 10.1111/php.14049

Sekar Monisha, Thangavel Myithili, Samuthirakani Ajithkumar, Kumaresan Sudharsan, Thangaraj Keerthana, Baskaran Sarikalakshmi, Mohan Pandi, Palanisamy Kalimuthu

{"title":"Aggregation assisted enhancement of singlet oxygen generation by 4-ethynylphenyl substituted porphyrin photosensitizer for photodynamic therapy.","authors":"Sekar Monisha, Thangavel Myithili, Samuthirakani Ajithkumar, Kumaresan Sudharsan, Thangaraj Keerthana, Baskaran Sarikalakshmi, Mohan Pandi, Palanisamy Kalimuthu","doi":"10.1111/php.14049","DOIUrl":"https://doi.org/10.1111/php.14049","url":null,"abstract":"Modulating the photophysical properties of photosensitizers is an effective approach to enhance singlet oxygen generation for photodynamic therapy. Porphyrins are the most widely used photosensitizers due to their biocompatible nature. Aggregation-induced emission (AIE) characteristics of photosensitizers are one of the advantageous features that will enhance fluorescence, intersystem crossing, and efficient triplet state generation. Herein, we demonstrate two glycosylated porphyrin photosensitizers, ZnGEPOH (with two ethynyl groups) and ZnGPOH (without two ethynyl groups), which exhibit AIE. Detailed studies revealed that ZnGEPOH exhibited a two-fold increase in singlet oxygen production than ZnGPOH due to AIE. The photo-cytotoxicity of ZnGPOH and ZnGEPOH were evaluated using cancer cell lines A549 and AGS. ZnGEPOH shows superior photo-cytotoxicity with cell viability of 21% and 19% for A549 and AGS, respectively, at 250 μg/mL concentration in 48 h. Moreover, ZnGEPOH exhibits minimal photo-cytotoxicity towards the control cell line HEK 293.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ocular safety of 222-nm far-ultraviolet-c full-room germicidal irradiation: A 36-month clinical observation. 222nm远紫外-c全室杀菌照射眼安全性：36个月临床观察。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2024-12-10 DOI: 10.1111/php.14052

Kazunobu Sugihara, Sachiko Kaidzu, Masahiro Sasaki, Sho Ichioka, Ichiya Sano, Katsunori Hara, Masaki Tanito

{"title":"Ocular safety of 222-nm far-ultraviolet-c full-room germicidal irradiation: A 36-month clinical observation.","authors":"Kazunobu Sugihara, Sachiko Kaidzu, Masahiro Sasaki, Sho Ichioka, Ichiya Sano, Katsunori Hara, Masaki Tanito","doi":"10.1111/php.14052","DOIUrl":"https://doi.org/10.1111/php.14052","url":null,"abstract":"The ocular safety of 222-nm far-ultraviolet-C (UV-C) irradiation, widely recognized for its germicidal properties, was evaluated in a clinical setting to assess its long-term health effects on the human eye. This prospective observational study involved a 36-month follow-up of physicians working in an ophthalmic examination room equipped with 222-nm UV-C lamps. Initially, a 12-month observation showed no signs of acute or chronic ocular damage. To further substantiate these findings, the study period was extended to 36 months, during which four participants underwent regular ocular examinations, including assessments of visual acuity, refractive error, and corneal endothelial cell density. The irradiation dose was meticulously controlled to remain within the previous threshold limit of 22 mJ/cm2 over an 8-h period, as advised by the ACGIH prior to 2022. Results indicated no significant changes in these parameters, suggesting no clinically significant ocular hazards associated with prolonged exposure to 222-nm UV-C irradiation under real-world conditions. Additionally, no delayed side effects, such as pterygium, keratopathies, or cataracts, were observed. Our study supports the safe use of 222-nm UV-C for microbial disinfection in occupied environments and provides a robust foundation for updated safety guidelines.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

520 nm and 660 nm light-emitting diodes modulates pancreatic development and beta cell functions in zebrafish embryos. 520nm和660nm发光二极管调节斑马鱼胚胎胰腺发育和β细胞功能。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2024-12-10 DOI: 10.1111/php.14050

Ünsal Veli Üstündağ, İsmail Ünal, Derya Cansız, Merih Beler, Naveen Krishna Kanagaraj, Amrish Rajendra Kumar, Ravindra Peravali, Ebru Emekli-Alturfan

{"title":"520 nm and 660 nm light-emitting diodes modulates pancreatic development and beta cell functions in zebrafish embryos.","authors":"Ünsal Veli Üstündağ, İsmail Ünal, Derya Cansız, Merih Beler, Naveen Krishna Kanagaraj, Amrish Rajendra Kumar, Ravindra Peravali, Ebru Emekli-Alturfan","doi":"10.1111/php.14050","DOIUrl":"https://doi.org/10.1111/php.14050","url":null,"abstract":"Green and Red LEDs increase insulin production, but their comparative effects on pancreatic and beta cell development are unclear. Zebrafish embryos were divided into three groups: Control (n = 60), Green (G) (n = 60), and Red (R) (n = 60), then irradiated for three days (14 hours/day) with 0.5 W/cm2 G (λpeak = 520 nm, 180 mA) and R (λpeak = 660 nm, 210 mA). At the end of 72 h, pancreatic and beta cells, circadian rhythm, and oxidative stress gene were analyzed using RT-PCR. Malondialdehyde, nitric oxide, superoxide dismutase, and glutathione levels were also evaluated. In the Red group, pancreatic area increased by ~97.13% compared to the Control group and by approximately ~62.16% compared to the G group (both p < 0.0001), and no significant difference in beta cell area (p = 0.964). G group insulin expression increased 2.31-fold compared to R group (p < 0.0001). Red LED treatment increased MDA levels (p < 0.001), oxidative stress (fth1b, nqo1) (p < 0.0001), and per1b during the photophase (p < 0.0001) compared to G group. R LED treatment increases oxidative stress and disrupts circadian rhythm, leading to reduced insulin secretion. The positive effects of G LED treatment have potential for metabolic syndrome, diabetes, and pancreatic diseases.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Caviar extract inhibits skin photoaging by activating skin stem cells through NF-κB/MMPs/COL17A1 axis. 鱼子酱提取物通过NF-κB/MMPs/COL17A1轴激活皮肤干细胞抑制皮肤光老化。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2024-12-03 DOI: 10.1111/php.14039

Younan Kou, Wuyan Guo, Yun Wang, Changhua Kou, Bo Zhang

{"title":"Caviar extract inhibits skin photoaging by activating skin stem cells through NF-κB/MMPs/COL17A1 axis.","authors":"Younan Kou, Wuyan Guo, Yun Wang, Changhua Kou, Bo Zhang","doi":"10.1111/php.14039","DOIUrl":"https://doi.org/10.1111/php.14039","url":null,"abstract":"Ultraviolet radiations (UVR) produce harmful entities and reactive oxygen species (ROS) in skin cells, leading to skin photoaging. Caviar extract (CE) showed outstanding effects in delaying skin aging, but the underlying mechanism remains largely unknown. In this study, we prepared CE with acid protease and examined the anti-skin photoaging effects. The results showed that CE performed no cytotoxicity to HaCaT cells. For antioxidant properties, the EC50 values of DPPH and ABTS radical scavenging activity for CE were 1.27 and 5.20 mg/mL, respectively. It significantly reduced NF-κB, MMP-3 and MMP-9 protein expression levels, and increased IκB and TIMP-1 expression level in UVA-irradiated HaCaT cells. In the skin aging mice model, CE reduced the degree of UV-induced skin photoaging. Histological study confirmed that CE can ameliorate the adverse effects of UV exposure on the skin. Moreover, we found that CE could enhance the activities of Superoxide dismutase (SOD), and increased the contents of hydroxyproline (HYP) in photoaged mice skin. And CE elevated the protein expression level of COL17A1, KRT10, and KRT14 in mice skin. Taken together, our results bright systemic and new insights of CE into preventing UV-induced skin photoaging.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0