Photochemistry and Photobiology最新文献

Transcranial photobiomodulation reduces predator-induced anxiety-like behavior (risk assessment) in male Rattus norvegicus threatened by Bothrops jararaca pit vipers. 经颅光生物调节可降低雄性褐家鼠在受到黑腹蝮蛇威胁时的焦虑样行为（风险评估）。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2026-10-15 DOI: 10.1111/php.70164

Ohana Turcato Macacare, Gustavo de Oliveira Tunis, Paloma Molina Hernandes, Norberto Cysne Coimbra

引用次数: 0

Preface for the special issue entitled Recent Advances in UVC Germicidal Science. 题为“UVC杀菌科学的最新进展”特刊的序言。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2026-10-15 DOI: 10.1111/php.70166

Manuela Buonanno, David Welch

引用次数: 0

VUV and mid-UV photoabsorption cross sections of thin films of glycine and alanine: Application to their photochemistry in the solar system. 甘氨酸和丙氨酸薄膜的紫外和中紫外光吸收截面：在太阳系光化学中的应用。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2026-10-14 DOI: 10.1111/php.70161

Juliette Pastore, Hervé Cottin, Kafila Saïagh, Jodie Belilla, Fabien Stalport, Nicolas Fray, Nathalie Carrasco

{"title":"VUV and mid-UV photoabsorption cross sections of thin films of glycine and alanine: Application to their photochemistry in the solar system.","authors":"Juliette Pastore, Hervé Cottin, Kafila Saïagh, Jodie Belilla, Fabien Stalport, Nicolas Fray, Nathalie Carrasco","doi":"10.1111/php.70161","DOIUrl":"https://doi.org/10.1111/php.70161","url":null,"abstract":"Experiments conducted in Low Earth Orbit (LEO) since the 1990s have investigated the evolution of organic matter in solid-phase (including amino acids) under solar photon irradiation to improve our understanding of its stability and reactivity on Solar System bodies. Interpreting results of such irradiation experiments requires detailed knowledge of the absorption properties of the exposed compounds, which are essential inputs for modeling their photochemical evolution in LEO. This study examines the photostability of two amino acids, glycine and alanine, which are prevalent in known life forms. The objective is to measure their photoabsorption cross sections and estimate photolysis rates within the VUV/UV range (50-300 nm). To achieve this, thin films of glycine and alanine (thickness from 10 to 100 nm) were prepared on MgF2 windows using a sublimation/recondensation method. The thickness of these deposits was accurately measured using interferometric microscopy and infrared spectroscopy. Subsequently, VUV/UV spectra of the samples were recorded, followed by calculation of the absorption cross sections and estimation of upper limits for photolysis rates and corresponding lower limits for half-lives of glycine and alanine in solid phase. These data provide quantitative constraints on amino acids photostability in extraterrestrial environments, improving the interpretation of irradiation experiments and photochemical models.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149183060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blue boost: Monochromatic blue light and blue-enriched spectra (RBW) enhance physiology, bioactive compounds, and yield of strawberry in indoor vertical farming. 蓝色提升：单色蓝光和蓝富集光谱（RBW）增强室内垂直种植草莓的生理、生物活性化合物和产量。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2026-10-13 DOI: 10.1111/php.70158

Carlos Henrique Pereira Bento, Fabia Barbosa da Silva, Márcio Rosa, Tiago do Prado Paim, Ítalo Moraes Rocha Guedes, Luciana Arantes Dantas, Erika Crispim Resende, Aurélio Rúbio Neto, Lucas de Jesus Silva, Nyah Dias Mazieri, Fabiano Guimarães Silva

{"title":"Blue boost: Monochromatic blue light and blue-enriched spectra (RBW) enhance physiology, bioactive compounds, and yield of strawberry in indoor vertical farming.","authors":"Carlos Henrique Pereira Bento, Fabia Barbosa da Silva, Márcio Rosa, Tiago do Prado Paim, Ítalo Moraes Rocha Guedes, Luciana Arantes Dantas, Erika Crispim Resende, Aurélio Rúbio Neto, Lucas de Jesus Silva, Nyah Dias Mazieri, Fabiano Guimarães Silva","doi":"10.1111/php.70158","DOIUrl":"https://doi.org/10.1111/php.70158","url":null,"abstract":"The demand for sustainable foods has driven indoor vertical farming, where strawberry-a high-value crop-responds strongly to light spectral quality. Blue, red, and RBW spectra regulate photosynthesis, morphogenesis, and bioactive compound synthesis. The strawberry cultivar Fragaria × ananassa 'Albion' was grown in an indoor vertical farming system under controlled temperature and humidity using a vertical aeroponic setup. Plants were exposed to four light spectra (white, red, blue, and RBW) and two light intensity regimes-constant and sinusoidal-to evaluate physiological, biochemical, yield, and phytochemical responses. Blue light increased chlorophyll a content and yield, while RBW lighting-particularly under a sinusoidal regime-improved photosynthetic balance, water use efficiency, fruit structure, and weight. Red light enhanced vegetative growth and fruit color and pH, but showed lower photosynthetic efficiency despite higher photochemical yield and SOD and CAT activity. Sinusoidal regimes, especially with RBW, promoted heavier, more intensely colored fruits and increased bioactive compounds, with spectrum-specific accumulation of gallic acid, rutin, cyanidin, kaempferol, quercetin, and catechin. Specific light spectra, especially RBW, improve strawberry physiological performance and fruit quality by increasing bioactive compounds, reinforcing vertical farming as a sustainable and high-performance production system.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149182364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validated computational modeling to evaluate spatial inactivation of airborne pathogens by Far-UVC irradiation. 验证计算模型评估远紫外线辐射对空气传播病原体的空间失活作用。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2026-10-10 DOI: 10.1111/php.70151

Camilo H Peñaloza, Andrew Wood, Ewan Eadie, Catherine Noakes, Marco-Felipe King, Kenneth Wood

{"title":"Validated computational modeling to evaluate spatial inactivation of airborne pathogens by Far-UVC irradiation.","authors":"Camilo H Peñaloza, Andrew Wood, Ewan Eadie, Catherine Noakes, Marco-Felipe King, Kenneth Wood","doi":"10.1111/php.70151","DOIUrl":"https://doi.org/10.1111/php.70151","url":null,"abstract":"Recent experimental studies have indicated the potential for ultraviolet C irradiation at 222 nm (Far-UVC) to be used in occupied rooms to safely reduce exposure to airborne pathogens. We present simulations coupling Monte Carlo radiation transfer with computational fluid dynamics to predict the spatial variation in airborne microorganism inactivation. Our simulations effectively reproduce data from steady-state experiments in a room-sized bioaerosol chamber for the reduction of aerosolized Staphylococcus aureus. Application of the validated model suggests that germicidal Far-UVC lamps could reduce levels of airborne human coronavirus by more than 90% in rooms with low ventilation rates. Depending on the UVC susceptibility of the aerosolized pathogen, Far-UVC lamps have the potential to provide in excess of 100 equivalent air changes per hour, much greater than is possible with mechanical ventilation or filtration devices. The success of our simulations at reproducing the experimental data provides confidence that we can simulate larger environments where steady-state airflow is appropriate and inform best practices for installations of germicidal Far-UVC lamps.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149149245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dose-dependent effects of photobiomodulation on stem cells from human exfoliated deciduous teeth cultured on polylactic acid films: An in vitro study. 光生物调节对聚乳酸膜培养人脱落乳牙干细胞的剂量依赖性研究。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2026-10-03 DOI: 10.1111/php.70160

Rômulo Augusto de Paiva Macedo, Vladimir Galdino Sabino, Hugo Alexandre Oliveira Rocha, Moacir Franco de Oliveira, Carlos Eduardo Bezerra de Moura, Carlos Augusto Galvão Barboza

{"title":"Dose-dependent effects of photobiomodulation on stem cells from human exfoliated deciduous teeth cultured on polylactic acid films: An in vitro study.","authors":"Rômulo Augusto de Paiva Macedo, Vladimir Galdino Sabino, Hugo Alexandre Oliveira Rocha, Moacir Franco de Oliveira, Carlos Eduardo Bezerra de Moura, Carlos Augusto Galvão Barboza","doi":"10.1111/php.70160","DOIUrl":"https://doi.org/10.1111/php.70160","url":null,"abstract":"This study investigated the effects of photobiomodulation (PBM) on stem cells from human exfoliated deciduous teeth (SHEDs) cultured on polylactic acid (PLA) films. Cells received a single 660-nm PBM application at nominal radiant exposures of 1 or 4 J/cm2 (L1 and L4); non-irradiated cultures comprised the control group (C). Metabolic activity was assessed by Alamar blue assay at 24, 48, and 72 h, cell cycle distribution by flow cytometry at 72 h, and morphology and surface coverage by scanning electron microscopy at 72 h. L4 showed greater metabolic activity than C at 24, 48, and 72 h, whereas L1 differed from C at 48 and 72 h (p < 0.05); L1 and L4 did not differ significantly. At 72 h, L4 showed a greater G2/M fraction than both C (p < 0.001) and L1 (p < 0.05). Irradiated cells exhibited greater apparent surface coverage while maintaining a fibroblast-like morphology. PBM therefore modulated metabolic activity, cell cycle distribution, and cell-material interactions in SHEDs cultured on PLA films, with the 4 J/cm2 condition showing the most consistent pattern. These results indicate a dose-related effect of PBM at the cell-biomaterial interface and suggest its potential role in tissue engineering approaches.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photobiomodulation alters base excision repair gene expression in an experimental model of arthritis. 光生物调节改变了关节炎实验模型中碱基切除修复基因的表达。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2026-09-30 DOI: 10.1111/php.70162

Victória Batista Ferreira, Álvaro Carneiro de Souza, Lúcia Mara Januário Dos Anjos, Ana Caroline da Silva Ferreira, Marcelle Abreu da Silva, Flávia de Paoli, Adenilson de Souza da Fonseca

{"title":"Photobiomodulation alters base excision repair gene expression in an experimental model of arthritis.","authors":"Victória Batista Ferreira, Álvaro Carneiro de Souza, Lúcia Mara Januário Dos Anjos, Ana Caroline da Silva Ferreira, Marcelle Abreu da Silva, Flávia de Paoli, Adenilson de Souza da Fonseca","doi":"10.1111/php.70162","DOIUrl":"https://doi.org/10.1111/php.70162","url":null,"abstract":"Arthritis is a chronic inflammatory disease characterized by a metabolic imbalance and oxidative stress, which can lead to significant DNA damage. While photobiomodulation (PBM) is a widely recognized non-invasive therapy for managing arthritic pain and inflammation, its effects on the mechanisms of DNA repair, specifically the Base Excision Repair (BER) pathway, remain unexplored in zymosan-induced arthritis. The objective of this study was to evaluate the effects of PBM on the mRNA levels of key BER genes in an experimental model of arthritis. Male C57BL/6 mice were subjected to zymosan-induced arthritis and treated with a low-power infrared laser (830 nm; 10 mW, 0.15 and 1.5 J, 15 and 150 s, 0.05 cm2, 200 mW/cm2, 3 or 30 J/cm2, continuous emission mode). Animals were euthanized at 24, 48, and 72 h post-induction, total mRNA was extracted from joint tissues, and transcription of APE1, POLβ, XRCC1, FEN1, and LIG1 genes was quantified using RT-qPCR. Zymosan-induced inflammation significantly altered relative mRNA levels of BER genes over time, generally increasing the expression of XRCC1, FEN1, and LIG1. PBM at 24 h, both 3 and 30 J/cm2 fluences, significantly reduced APE1, FEN1, and LIG1 mRNA levels. At 48 h, PBM reduced XRCC1, FEN1, and LIG1 expression but, at 72 h, PBM increased transcription of LIG1 gene. Transcription of POLβ gene was not significantly affected. These findings suggest that PBM modulates the relative mRNA levels of genes involved in both the short-patch and long-patch BER pathways in zymosan-induced arthritis.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experimental study on the influence of pupil diameter on laser-induced retinal damage effects. 瞳孔直径对激光视网膜损伤影响的实验研究。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2026-09-25 DOI: 10.1111/php.70147

ZuKang Nie, MengQi Qiu, LiTong Zhu, JiaRui Wang, LuGuang Jiao, Bin Su, Rui Guo, ZaiFu Yang

{"title":"Experimental study on the influence of pupil diameter on laser-induced retinal damage effects.","authors":"ZuKang Nie, MengQi Qiu, LiTong Zhu, JiaRui Wang, LuGuang Jiao, Bin Su, Rui Guo, ZaiFu Yang","doi":"10.1111/php.70147","DOIUrl":"https://doi.org/10.1111/php.70147","url":null,"abstract":"To investigate the impact of pupil diameter on laser-induced retinal damage, this study employed 473 nm and 1064 nm lasers to irradiate the retinas of Chinchilla rabbits, with an exposure duration of 0.1 s. Apertures of 2 and 5 mm were placed in front of the dilated eyes to simulate pupil conditions in bright and dim environments. Five dose groups were set for each of the four exposure conditions. Retinal damage was assessed at 1 and 24 h post-irradiation by fundus photography and optical coherence tomography (OCT), and the retinal damage threshold (ED50) was determined from the damage incidence collected from fundus photographs. Threshold-level retinal lesions presented as grayish-white coagulation spots. For the 473 nm laser, the ED50 values, expressed as total intraocular energy (TIE), were 1.53 and 2.10 mJ for the 2 and 5 mm apertures, respectively, corresponding to corneal radiant exposures of 48.7 and 10.7 mJ/cm2. For the 1064 nm laser, the ED50 values were 38.9 and 67.1 mJ for the 2 and 5 mm apertures, respectively, with corresponding corneal radiant exposures of 1239.3 and 341.7 mJ/cm2. These findings demonstrate that when evaluated in terms of corneal radiant exposure, the retinal damage threshold is lower for larger pupil diameters; when assessed in terms of TIE, the retinal damage threshold is lower for smaller pupil diameters.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149063809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

233 nm far-UV-C radiation for biofilm inactivation. 233nm远紫外- c辐射灭活生物膜。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2026-09-25 DOI: 10.1111/php.70153

Paula Zwicker, Antonia Maja Lotta Bradtke, Neysha Lobo Ploch, Nils-Olaf Hübner

{"title":"233 nm far-UV-C radiation for biofilm inactivation.","authors":"Paula Zwicker, Antonia Maja Lotta Bradtke, Neysha Lobo Ploch, Nils-Olaf Hübner","doi":"10.1111/php.70153","DOIUrl":"https://doi.org/10.1111/php.70153","url":null,"abstract":"The formation of biofilms protects bacteria from antibiotic therapy or disinfection based on different mechanisms. The treatment of biofilms is furthermore impeded by their characteristic of being composed of multiple species; thus, it is necessary to identify involved species to determine an appropriate treatment. Consequently, new methods for inactivating involved bacteria in biofilms are necessary. One possibility might be the use of skin-compatible doses of 233 nm far-UV-C irradiation. In the presented study, the potential for biofilm formation of various bacteria species and strains was identified using a plate-based assay (crystal violet staining) as well as two cultivation-based assays on agar plates (Congo red, calcofluor). Strains of S. aureus, S. epidermidis, and P. aeruginosa were selected and grown on stainless steel carriers for 24 h followed by irradiation with skin-tolerable doses of 233 nm far-UV-C radiation (20-80 mJ/cm2). Viability of bacteria was assessed via quantification of colony-forming units. Irradiation led to a statistically significant inactivation of up to 2.28 lg (S. epidermidis), 2.60 lg (S. aureus), and 1.16 lg (P. aeruginosa). Higher doses tended to result in slightly higher inactivation, but without statistical significance. Since UV-C irradiation does not remove bacteria and the surrounding matrix, additional cleansing is necessary for biofilm removal. But UV-C irradiation can be an effective addition to cleansing and chemical treatment for biofilm inactivation. Therefore, for potential applications on skin or mucous membranes, UV-C currently represents a valuable additional method that broadens the antiseptic treatment repertoire.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149063769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revisiting the action spectrum of DNA damage: Chemiexcitation and the expanded biological spectrum of cyclobutane pyrimidine dimer formation. 重新审视DNA损伤的作用谱：环丁烷嘧啶二聚体形成的化学激发和扩展的生物谱。

IF 2.6 4区生物学

Photochemistry and Photobiology Pub Date : 2026-09-23 DOI: 10.1111/php.70154

Jyoti Srivastava, Marcus S Cooke, Sanjay Premi

{"title":"Revisiting the action spectrum of DNA damage: Chemiexcitation and the expanded biological spectrum of cyclobutane pyrimidine dimer formation.","authors":"Jyoti Srivastava, Marcus S Cooke, Sanjay Premi","doi":"10.1111/php.70154","DOIUrl":"10.1111/php.70154","url":null,"abstract":"The action spectrum of cyclobutane pyrimidine dimer (CPD) formation has long been viewed as reflecting the DNA absorption spectrum and closely aligned with the erythema (sunburn) spectrum. This alignment established the prevailing paradigm in which erythema serves as a surrogate for mutagenic risk and ultraviolet B radiation (UVB) is responsible for biologically meaningful DNA damage in skin. However, the discovery of delayed or \"dark\" CPDs, generated through post-exposure biochemical processes such as melanin-dependent chemiexcitation, extends and refines this classical view. It is increasingly well established that CPD formation is not limited to direct photon absorption but can additionally arise through longer-wavelength, redox-driven chemiexcitation pathways, particularly within the UVA range. Emerging evidence further suggests that non-melanin oxidative pathways, including lipid peroxidation, can generate chemiexcited states potentially relevant to DNA damage. In light of this evidence, we propose that the biological action spectrum for CPD formation is determined not only by direct DNA absorption, but also by the capacity of cells to generate DNA damaging excited states through redox chemistry. This novel framework reshapes how light exposure is linked to mutagenesis and underscores the need for next-generation photoprotective strategies targeting both direct and indirect DNA damage pathways.","PeriodicalId":20133,"journal":{"name":"Photochemistry and Photobiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149031117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0