Photomedicine and laser surgery最新文献

{"title":"In Vivo Analysis of Photobiomodulation Genotoxicity Using the Somatic Mutation and Recombination Test.","authors":"Magda Patrícia Furlanetto,&nbsp;Ivana Grivicich,&nbsp;Rafael Rodrigues Dihl,&nbsp;Mauricio Lehmann,&nbsp;Daniel Silva de Souza,&nbsp;Rodrigo Della Méa Plentz","doi":"10.1089/pho.2018.4468","DOIUrl":"https://doi.org/10.1089/pho.2018.4468","url":null,"abstract":"<p><strong>Background: </strong>Photobiomodulation (PBM) has been studied mainly for its effects on the repair, regeneration, and healing of tissue due to its direct and indirect actions on cell proliferation. However, it is necessary to consider the way in which laser acts, that is, whether it affects the rates of spontaneous mutation and mitotic recombination of cells.</p><p><strong>Objective: </strong>This study investigated the genotoxic potential of PBM (904 nm) based on an in vivo bioassay that concomitantly evaluates mitotic recombination and point and chromosomal mutations.</p><p><strong>Methods: </strong>Strains of Drosophila melanogaster that carry specific marker genes were used to detect the induction of mutation and somatic recombination when exposed to different fluences (3, 5, 10, and 20 J/cm²). DNA damage was measured using the somatic mutation and recombination test (SMART), which is based on the identification of wing hair with mutant phenotypes that express lesions at DNA level.</p><p><strong>Results: </strong>The doses 5, 10, and 20 J/cm² induced significant increase in the total number of spots compared with the negative control. The highest frequency of spots was caused by the 10 J/cm².</p><p><strong>Conclusions: </strong>Besides recombination events, the quantitative and qualitative analysis of mutant hairs revealed the occurrence of mutagenic events, both punctual and chromosomal. In addition, the results point to a dose-dependent response.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 10","pages":"536-540"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2018.4468","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36523279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Effects of Intense Pulsed Light Combined with Meibomian Gland Expression in the Treatment of Meibomian Gland Dysfunction.","authors":"Bei Rong,&nbsp;Yun Tang,&nbsp;Ruixing Liu,&nbsp;Ping Tu,&nbsp;Jing Qiao,&nbsp;Wenjing Song,&nbsp;Xiaoming Yan","doi":"10.1089/pho.2018.4499","DOIUrl":"https://doi.org/10.1089/pho.2018.4499","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the long-term effects of intense pulsed light (IPL) combined with meibomian gland expression (MGX) in the treatment of meibomian gland dysfunction (MGD).</p><p><strong>Background: </strong>Although IPL has been proven to be effective in the treatment of MGD, any report regarding its long-term efficacy is unavailable by now.</p><p><strong>Methods: </strong>The randomly selected study eye received a series of three IPL treatments that were applied directly on eyelids with an interval of 4 weeks (treatment energy, 14-16 J/cm²). The control eye received three sham IPL treatments (0 J/cm²). MGX was performed on both eyes. Meibomian gland yielding secretion score (MGYSS) and tear film break-up time (TBUT) were evaluated at baseline and at 1, 3, 6, and 9 months after treatments.</p><p><strong>Results: </strong>In the study eyes, MGYSS of both the upper and lower eyelids and TBUT improved at 1, 3, 6 months after treatments (p < 0.01). MGYSS in lower eyelids continued to improve at 9 months (p < 0.05). The changes in MGYSS and TBUT after treatment were larger in the study eyes than in the control eyes at 1, 3, 6 months (p < 0.01), but no difference at 9 months (p > 0.05). The percentage improvement in the MGYSS of lower eyelids after treatment was higher than that of upper eyelids.</p><p><strong>Conclusions: </strong>Three consecutive IPL treatments combined with MGX improved MG secretion function and TBUT by 6 months after treatment in MGD patients. The improvement in MG secretion function was greater in the lower eyelid than in the upper eyelid.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 10","pages":"562-567"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2018.4499","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36523823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bactericidal Effect of Various Laser Irradiation Systems on Enterococcus faecalis Biofilms in Dentinal Tubules: A Confocal Laser Scanning Microscopy Study.","authors":"Xiaoli Wang,&nbsp;Xiaogang Cheng,&nbsp;Xin Liu,&nbsp;Zhihua Wang,&nbsp;Juan Wang,&nbsp;Cuihong Guo,&nbsp;Yaqing Zhang,&nbsp;Wenxi He","doi":"10.1089/pho.2017.4430","DOIUrl":"https://doi.org/10.1089/pho.2017.4430","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to compare the bactericidal effect of various laser irradiation systems on Enterococcus faecalis biofilms in dentinal tubules by using a novel dentin infection model and confocal laser scanning microscopy (CLSM).</p><p><strong>Background data: </strong>Laser-activated irrigations have been proposed as an adjuvant to conventional protocols of root canal treatment to enhance the smear layer removal, which is a promising protocol for root canal disinfection.</p><p><strong>Materials and methods: </strong>E. faecalis were centrifuged into the dentinal tubules, cultured for 3 weeks, and then received 1- and 3-min treatments as follows: (A) 5.25% sodium hypochlorite (NaOCl) irrigation, (B) Nd:YAG laser irradiation, (C) diode laser irradiation, (D) Nd:YAP laser irradiation, (E) Er,Cr:YSGG laser-activated NaOCl irrigation, and (F) Er:YAG laser-activated NaOCl irrigation. Bacterial reductions were assessed by CLSM using a LIVE/DEAD^® bacterial viability stain method.</p><p><strong>Results: </strong>For each group, the bacterial reduction increased as the treatment time increased (p < 0.05). The Er,Cr:YSGG and Er:YAG laser significantly enhanced the bactericidal effect of NaOCl (p < 0.05). Under the conditions of the same treatment time, bacterial reductions were presented in the descending order of Er:YAG + NaOCl, Er,Cr:YSGG + NaOCl > Nd:YAP > Nd:YAG, diode > NaOCl.</p><p><strong>Conclusions: </strong>Under the conditions of present study, treatments of Er:YAG + NaOCl and Er,Cr:YSGG + NaOCl presented the strongest bactericidal effect among the tested protocols and are potential protocols for root canal disinfection.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 9","pages":"472-479"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4430","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36064659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-Level Laser Therapy and World Association for Laser Therapy Dosage Recommendations in Musculoskeletal Disorders and Injuries.","authors":"Rodrigo Alvaro B Lopes-Martins,&nbsp;Rodrigo Labat Marcos,&nbsp;Ernesto Cesar Pinto Leal-Junior,&nbsp;Jan Magnus Bjordal","doi":"10.1089/pho.2018.4493","DOIUrl":"https://doi.org/10.1089/pho.2018.4493","url":null,"abstract":"","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 9","pages":"457-459"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2018.4493","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36467863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of Skeletal Muscle Strain Lesion Induced by Stretching in Rats: Effects of Laser Photobiomodulation.","authors":"Luciano Ramos,&nbsp;Rodrigo Labat Marcos,&nbsp;Romildo Torres-Silva,&nbsp;Rodney Capp Pallota,&nbsp;Tatiana Magacho,&nbsp;Fernando Francisco Pazello Mafra,&nbsp;Michel Monteiro Macedo,&nbsp;Rodrigo Leal de Paiva Carvalho,&nbsp;Jan Magnus Bjordal,&nbsp;Rodrigo Alvaro B Lopes-Martins","doi":"10.1089/pho.2018.4473","DOIUrl":"https://doi.org/10.1089/pho.2018.4473","url":null,"abstract":"<p><strong>Background: </strong>Unusual and exhaustive physical exercise can lead to muscle lesions depending on the type of contraction, intensity, duration, age, and level of conditioning. Different therapies have been proposed to prevent or reduce exercise-induced muscle damage.</p><p><strong>Objective: </strong>In this study, we investigate the effects of low-level laser therapy on skeletal muscle strain in an experimental model in rats.</p><p><strong>Materials and methods: </strong>Male Wistar rats (200 g) were used. The animals were randomized into groups of six animals. We performed tibialis muscle elongation using a previously described protocol. The animals were anesthetized and submitted to passive stretching of the anterior tibial muscle attached to a weight corresponding to 150% of the body mass of the animal for 20 min, rested for 3 min, and received a second traction for 20 min. The cytokines, tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), IL-6, and IL-10, edema, and C-reactive protein (CRP) levels were determined in the tibialis anterior muscle.</p><p><strong>Results: </strong>Plasma extravasation of groups treated with different doses of laser energy, lesion +1 J (2.61 ± 0.46), lesion +3 J (2.33 ± 0.13), lesion +6 J (2.92 ± 0.91), and lesion +9 J (2.80 ± 0.55), shows a significant reduction of extravasation when compared with the injury group (5.46 ± 1.09). Laser therapy was able to significantly reduce CRP and cytokine levels (TNF-α, IL-1β, IL-6, and IL-10).</p><p><strong>Conclusions: </strong>Laser photobiomodulation reduced skeletal muscle edema as well as cytokines and CRP, leading to a significant reduction in inflammatory markers.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 9","pages":"460-467"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2018.4473","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36387675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Er,Cr:YSGG Laser Handpieces for Class II Preparation and Microleakage of Silorane- or Methacrylate-Based Composite Restorations.","authors":"Esra Ergin,&nbsp;Fatma Dilsad Oz,&nbsp;Sevil Gurgan","doi":"10.1089/pho.2018.4459","DOIUrl":"https://doi.org/10.1089/pho.2018.4459","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate the influence of cavity preparation with different Er,Cr:YSGG laser handpieces on microleakage of different posterior composite restorations.</p><p><strong>Methods: </strong>Fifty-four extracted intact human premolars were randomly assigned to three groups according to cavity preparation method: Bur Group: high-speed diamond bur (Diatech), MD Group: Er,Cr:YSGG laser Waterlase MD handpiece (Biolase Millennium II), and Turbo Group: Er,Cr:YSGG laser Waterlase MD TURBO handpiece (Biolase Millennium II). One hundred eight Class II slot cavities were prepared on the mesial and distal proximal surfaces of each tooth, and the cavity preparation times required were determined. The groups were then subdivided according to the restorative systems used (n = 12): a conventional methacrylate-based microhybrid composite (Filtek P60+Adper Single Bond 2/3M); a silorane-based resin composite (Filtek Silorane+Silorane System Adhesive/3M); and a nanohybrid methacrylate-based composite (Kalore+G-Bond/GC). The restorative systems were applied according to the manufacturers' recommendations. Following thermocycling (X5000; 5°C-55°C), the teeth were coated with nail varnish except the restoration margins, immersed in 0.5% basic fuchsin dye solution, and sectioned in a mesiodistal direction. Dye penetration was evaluated under a light microscope for occlusal and cervical margins. Data were analyzed with one-way ANOVA and chi-square tests (p < 0.05).</p><p><strong>Results: </strong>The cavity preparation time (mean ± SD) required for Bur, MD, and Turbo group was 31.25 ± 3.82, 222.94 ± 15.85, and 92.5 ± 7.42 sec, respectively, and the differences among the groups were statistically significant (p < 0.05). Comparing the occlusal and cervical microleakage scores, no statistically significant differences were found among the groups and subgroups (p > 0.05).</p><p><strong>Conclusions: </strong>Er;Cr:YSGG laser cavity preparation with the Turbo handpiece needed shorter time than the MD handpiece, although it needed longer time than the conventional diamond bur. The use of different handpieces of Er,Cr:YSGG laser did not differ from conventional preparation with diamond bur in terms of microleakage with the tested methacrylate- and silorane-based posterior composite restorative systems.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 9","pages":"499-505"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2018.4459","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36467864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Protein Testing Model to Assay the Efficacy of Multiple Irrigation Activation Techniques for Removal of Ex Vivo Biomolecular Film.","authors":"Hicran Dönmez Özkan,&nbsp;Kubilay Metin,&nbsp;Zehra Burcu Bakir,&nbsp;Senem Yiğit Özer","doi":"10.1089/pho.2018.4452","DOIUrl":"https://doi.org/10.1089/pho.2018.4452","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare the debris removal efficacies of irrigation activation techniques using ex vivo biomolecular film.</p><p><strong>Materials and methods: </strong>Root canals of 50 human mandibular premolars were prepared, and freshly prepared collagen solutions were applied into the root canals using a peristaltic pump. Specimens were randomly divided into the five groups and irrigated with 3 mL of 5.25% sodium hypochlorite (NaOCl): G1 (needle irrigation and control group): a 27-gauge notched-tip irrigation needle (Endo-Eze; Ultradent, South Jordan, UT); G2, Vibringe sonic irrigation system (VSS) (Vibringe B.V. Corp., Amsterdam, Netherlands); G3, EndoActivator sonic irrigation system (EA) (Dentsply Tulsa Dental Specialties, Tulsa, OK); G4, passive ultrasonic irrigation (PUI) (EMS, Nyon, Sweden); and G5, photon-induced photoacoustic streaming (PIPS) (Fotona, Ljubljana, Slovenia). Postirrigation solution was collected in beakers containing 3% sodium thiosulfate by which NaOCl solution was neutralized. Residual protein levels in NaOCl solution were evaluated by the Bradford method. Data were analyzed using ANOVA with Duncan post hoc tests (α = 0.05).</p><p><strong>Results: </strong>PIPS (laser-activated irrigation) method removed more artificial collagen than other experimental groups (EA, PUI, VSS) or the control group (p ≤ 0.05). There were no statistical differences among the EA, PUI, and VSS groups. The PIPS, PUI, and EA groups were superior compared with the conventional irrigation (p ≤ 0.05); however, there were no significant differences between VSS and the conventional irrigation groups.</p><p><strong>Conclusions: </strong>Although all the methods and techniques examined in this study were suitable in extruding the ex vivo biomolecular film, the PIPS method was found significantly more effective than all the other tested groups (p ≤ 0.05).</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 9","pages":"493-498"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2018.4452","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36387673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Change of Tinnitus with Xenon Phototherapy of the Stellate Ganglion.","authors":"Masako Shimizu,&nbsp;Takashi Matsuzuka,&nbsp;Fumiaki Matsumi,&nbsp;Hiroshi Ogawa,&nbsp;Shigeyuki Murono","doi":"10.1089/pho.2017.4431","DOIUrl":"https://doi.org/10.1089/pho.2017.4431","url":null,"abstract":"<p><strong>Objective: </strong>To develop a treatment for tinnitus called xenon phototherapy of the stellate ganglion (XPSG) and analyze its effect on tinnitus.</p><p><strong>Methods: </strong>Patients with chronic tinnitus received XPSG. Symptoms were assessed subjectively with tinnitus handicap inventory (THI) and numerical rating scale (NRS). THI and NRS scores were analyzed in XPSG (n = 43) and sham treatment (non-XPSG) (n = 18) groups.</p><p><strong>Results: </strong>THI and NRS scores improved significantly after 3 months of XPSG. Severe cases with high THI or NRS score showed greater improvement. No significant difference was observed between before and after sham treatment in non-XPSG groups.</p><p><strong>Conclusions: </strong>XPSG significantly improved THI and NRS scores with high patient satisfaction.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 9","pages":"468-471"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4431","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36387670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Effect of Pulsed Nd:YAG Laser in the Treatment of Patients with Rotator Cuff Tendinopathy: A Randomized Controlled Trial.","authors":"Ahmed Mohamed Elsodany,&nbsp;Mohamed Salaheldien Mohamed Alayat,&nbsp;Mohamed Mohamed Ebrahim Ali,&nbsp;Hussien Mosa Khaprani","doi":"10.1089/pho.2018.4476","DOIUrl":"https://doi.org/10.1089/pho.2018.4476","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of the present study was to investigate the long-term effect of pulsed Nd:YAG laser on the treatment of rotator cuff tendinopathy.</p><p><strong>Methods: </strong>Sixty patients with rotator cuff tendinopathy participated and completed the study. The mean age was 50.2 ± 3.6 years. Participants were randomly assigned to one of two groups: the control group and the treatment group. Both groups were treated with an exercise program, in addition to the pulsed Nd:YAG laser received by the treatment group and the \"sham\" laser received by the control group, both for three sessions per week for 4 weeks. Outcome measures included pain, assessed by the visual analog scale, and range of motion (ROM), assessed using a traditional goniometer, while the shoulder pain and disability index were used to evaluate the functional recovery of the shoulder joint. Evaluation was carried out before treatment, immediately after treatment, 3 months posttreatment, and 6 months posttreatment. Statistical analyses were used to investigate the effect of interventions and to compare the study groups' pretreatment, posttreatment, and at follow-up points. The significance level was set to p < 0.05.</p><p><strong>Results: </strong>Pain was significantly decreased after treatment and at follow-up points, while ROM and shoulder functions were significantly improved after treatment and at follow-up intervals in both groups. The improvement was more significant in the treatment group than in the control group posttreatment and at follow-up intervals.</p><p><strong>Conclusions: </strong>Pulsed Nd:YAG laser combined with an exercise program seems to be more effective in the treatment of patients with rotator cuff tendinopathy than a sham laser with exercises.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 9","pages":"506-513"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2018.4476","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36465124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Root Canal Anatomy of Maxillary Premolars Using Swept-Source Optical Coherence Tomography in Comparison with Dental Operating Microscope and Cone Beam Computed Tomography.","authors":"Bayan Rashed,&nbsp;Yoshiko Iino,&nbsp;Kei Komatsu,&nbsp;Miki Nishijo,&nbsp;Takahiro Hanada,&nbsp;Arata Ebihara,&nbsp;Mitsuhiro Sunakawa,&nbsp;Yasunori Sumi,&nbsp;Takashi Okiji","doi":"10.1089/pho.2017.4416","DOIUrl":"https://doi.org/10.1089/pho.2017.4416","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the ability of swept-source optical coherence tomography (OCT) to detect internal anatomy of maxillary premolars in comparison with dental operating microscope (DOM) and cone beam computed tomography (CBCT).</p><p><strong>Background data: </strong>The ability of OCT to observe the pulp horn during cavity preparation and assess the remaining dentin thickness (RDT) has been demonstrated, whereas validation of OCT in comparison with other imaging techniques seems required.</p><p><strong>Methods: </strong>Ten extracted human maxillary premolars were sectioned perpendicular to the tooth axis from the occlusal surface at approximately 2 mm increments. OCT and DOM were performed after each cut, and microfocus X-ray computed tomography (micro-CT; reference standard) and CBCT were conducted before sectioning and after the first and second cuts. Three examiners evaluated all images for presence of the pulp horn/pulp chamber, isthmus, lateral canals, and the number of root canals. RDT was determined from OCT, micro-CT, and CBCT images. Correlations were analyzed with Pearson's correlation coefficient.</p><p><strong>Results: </strong>OCT had a sensitivity and specificity of 0.90 and 0.80 in detecting the pulp horn/pulp chamber and 0.84 and 0.71 in detecting the isthmus, respectively. The three techniques showed strong correlations in detecting the number of root canals compared with micro-CT. OCT and DOM did not detect lateral canals. For RDT values, strong correlations were observed between micro-CT and CBCT, micro-CT and OCT, and CBCT and OCT (p < 0.01 for all).</p><p><strong>Conclusions: </strong>Under the present experimental condition, OCT accurately measured RDT and detected internal tooth anatomy such as the pulp horn, isthmus, and root canals.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 9","pages":"487-492"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4416","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36387669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}