Photobiomodulation, photomedicine, and laser surgery最新文献

{"title":"Photobiomodulation Literature Watch August 2022.","authors":"James D Carroll","doi":"10.1089/photob.2022.0139","DOIUrl":"https://doi.org/10.1089/photob.2022.0139","url":null,"abstract":"","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 1","pages":"30-32"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10628933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photobiomodulation (800 nm Light-Emitting Diode) Treatment Promotes Bone Mesenchymal Stem Cell Proliferation Via Long Noncoding RNA MEG3-MicroRNA-217-5P Pathway.","authors":"Na Liu,&nbsp;Lan Cao,&nbsp;Lei Peng,&nbsp;Weiwei Lu,&nbsp;Xiaolin Dai,&nbsp;Shengyu Wang,&nbsp;Guangqiong Guo,&nbsp;Xiaowen Qu,&nbsp;Ying Xu,&nbsp;Chongtao Zhu","doi":"10.1089/photob.2021.0187","DOIUrl":"https://doi.org/10.1089/photob.2021.0187","url":null,"abstract":"<p><p><b><i>Background:</i></b> Patients with osteoporosis (OP) have a high risk of bone fracture. Abnormal bone mesenchymal stem cell (BMSC) differentiation is an essential process of OP development. In recent years, photobiomodulation has been shown to effectively promote BMSC proliferation. However, the mechanism by which photobiomodulation promotes BMSC proliferation is unclear. Long noncoding RNAs (lncRNAs) are essential mediators in multiple biological processes. The lncRNA maternally expressed gene 3 (MEG3) is a novel lncRNA gene and is related to cell proliferation. Studies have indicated that MEG3 serves as a promotor in BMSC proliferation. <b><i>Objective:</i></b> To investigate the effects and mechanisms of 800 nm light-emitting diode (LED) photobiomodulation in BMSC proliferation. <b><i>Materials and methods:</i></b> The BMSCs collected from mouse tibias and femurs were irradiated by 800 nm LED for 180 sec. CCK-8 assay was used to detect the cell viability. A dual-luciferase reporter assay was used to determine IncRNA MEG3 acted as a miR-217-5p sponge. We used reverse transcription-polymerase chain reaction (RT-PCR) and western blot to detect the mRNA and protein levels of MEG3, miR-217-5p, Notch2, Hes1, Hey2. <b><i>Results:</i></b> In the present study, we revealed that photobiomodulation (800 nm LED) could increase the mRNA level of MEG3, and protein levels of Notch2, Hes1, and Hey2. Moreover, we also identified that upregulated MEG3 could act as a miR-217-5p sponge to activate the Notch signaling pathway. <b><i>Conclusions:</i></b> The current study revealed the MEG3-related mechanism of photobiomodulation treatment in OP and identified potential gene therapies for OP.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 1","pages":"10-16"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10521653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photobiomodulation Therapy for Treatment of Extravasation Injuries in Cancer Chemotherapy.","authors":"Michael R Hamblin","doi":"10.1089/photob.2022.0126","DOIUrl":"https://doi.org/10.1089/photob.2022.0126","url":null,"abstract":"","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10628932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acknowledgment of Reviewers 2022.","authors":"","doi":"10.1089/photob.2022.29026.ack","DOIUrl":"https://doi.org/10.1089/photob.2022.29026.ack","url":null,"abstract":"","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 1","pages":"33-34"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10513795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Herpes Zoster Secondary to Systemic Lupus Erythematosus Successfully Treated with Ultraviolet A1 Phototherapy: A Case Report.","authors":"Minmin Kong,&nbsp;Jian Li,&nbsp;Huan Wang,&nbsp;Zhiqiang Song,&nbsp;Qiquan Chen","doi":"10.1089/photob.2022.0097","DOIUrl":"https://doi.org/10.1089/photob.2022.0097","url":null,"abstract":"<p><p><b><i>Background:</i></b> The incidence of herpes zoster (HZ) in systemic lupus erythematosus (SLE) patients is high, and the symptoms are usually severe and resistant to treatment, and the prognosis is poor. Ultraviolet (UV) A1 is a band of UV light, and UVA1 phototherapy has been widely used to treat various inflammatory skin diseases. <b><i>Objective:</i></b> At present, UVA1 has been considered as a potential adjuvant therapy for HZ in SLE patients. To the best of our knowledge, this is the first case report concerning the successful application of UVA1 in the treatment of HZ secondary to SLE. <b><i>Methods:</i></b> In this article, a clinical case report is presented, wherein the patient did not respond to conventional treatment, but was markedly responsive to the treatment of UVA1 phototherapy, and well tolerated. <b><i>Results:</i></b> A 29-year-old woman with severe HZ secondary to SLE was successfully treated with UVA1 phototherapy. <b><i>Conclusions:</i></b> UVA1 phototherapy can be used as an effective adjuvant treatment for HZ secondary to SLE.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 1","pages":"26-29"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10529024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photobiomodulation Literature Watch July 2022.","authors":"James D Carroll","doi":"10.1089/photob.2022.0099","DOIUrl":"https://doi.org/10.1089/photob.2022.0099","url":null,"abstract":"","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"40 12","pages":"826-828"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10385686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Polarized Light Therapy (Bioptron) on Wound Healing and Microbiota in Diabetic Foot Ulcer: A Randomized Controlled Trial.","authors":"Mona Mohamed Taha,&nbsp;Mai M El-Nagar,&nbsp;Basant Hamdy Elrefaey,&nbsp;Reem Mohsen Elkholy,&nbsp;Olfat Ibrahim Ali,&nbsp;Nouf Alkhamees,&nbsp;El-Sayed Essam El-Sayed Felaya","doi":"10.1089/photob.2021.0175","DOIUrl":"https://doi.org/10.1089/photob.2021.0175","url":null,"abstract":"<p><p><b><i>Background:</i></b> Diabetic foot ulcer (DFU) complications are the most common cause of morbidity in diabetic patients. Bioptron light therapy is a new adjuvant therapy for wound healing. This study aimed to investigate the effect of polarized light therapy on the healing and microbial nature of DFUs. <b><i>Methods:</i></b> Forty type 2 diabetic patients with Wagner grade 1 or 2 DFUs were randomly assigned to one of two groups: the light therapy group, which received Bioptron light therapy using the Bioptron lamp for 12 min three times per week, plus standard wound care, or the control group, which received standard wound care only. Both interventions were given over a 2-month period. Wound surface area, volume, and ulcer microbial cultures were all measured before and after the study period. <b><i>Results:</i></b> There was a significant reduction in ulcer surface area between groups in favor of the light therapy group, with a relative ulcer size reduction of 51.44% ± 23.76% compared with 24.5% ± 9.6% in the control group (<i>p</i> < 0.001). Besides, a significant difference was observed between groups in the microbial cultures (<i>p</i> = 0.02); by the end of the 8th week, the number of patients with negative ulcer culture was 12 (60%) in the light therapy group compared with 3 (15%) in the control group. <b><i>Conclusions:</i></b> Bioptron light therapy seems to be an effective therapeutic intervention combined with standard care in decreasing wound size and reducing ulcer microbiota for DFUs. It reduces ulcer bacterial infection and speeds up ulcer healing. Trial registration: ClinicalTrials.gov: NCT04446767.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"40 12","pages":"792-799"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10703890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Adjunctive Photobiomodulation in the Management of Medication-Related Osteonecrosis of the Jaw: A Systematic Review.","authors":"Pouyan Razavi,&nbsp;Aryan Jafari,&nbsp;Paolo Vescovi,&nbsp;Reza Fekrazad","doi":"10.1089/photob.2022.0084","DOIUrl":"https://doi.org/10.1089/photob.2022.0084","url":null,"abstract":"<p><p><b><i>Background:</i></b> Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse medication response that manifests as progressive bone necrosis in the craniofacial area. There is still no clear treatment protocol for the management of MRONJ. The purpose of this study was to conduct a systematic review to assess the efficacy of photobiomodulation (PBM) as an adjunct to MRONJ therapy. <b><i>Methods:</i></b> In line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, a literature search was performed on PubMed/MEDLINE, Scopus, Web of Science, and Cochrane databases. Two examiners examined eligibility and risk of bias separately before extracting data. <b><i>Results:</i></b> Two hundred sixty-nine articles were found through electronic search, out of which only 11 met the inclusion criteria and were included in qualitative synthesis (9 retrospectives, 1 prospective, and 1 case series). A total number of 759 patients and a mean age ranging from 54 to 74 years were reviewed. Females were the most frequent gender in all of the selected studies (72% females to 28% males), and the most frequent stage in the studies mentioned above was stage II (66%). Most of the studies had shown a significant improvement when PBM was used as an adjunctive treatment. <b><i>Conclusions:</i></b> Based on the results of this study, PBM as an adjuvant therapy can significantly improve the outcomes of each treatment plan. However, surgical intervention for the complete healing of the lesions is suggested.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"40 12","pages":"777-791"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10687687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phototherapy of <i>Pseudomonas aeruginosa</i>-Infected Wounds: Preclinical Evaluation of Antimicrobial Blue Light (450-460 nm) Using <i>In Vitro</i> Assays and a Human Wound Skin Model.","authors":"Marie-Charlotte D Leder,&nbsp;Mahsa Bagheri,&nbsp;Isabell Plattfaut,&nbsp;Paul C Fuchs,&nbsp;Anne K E Brüning,&nbsp;Jennifer L Schiefer,&nbsp;Christian Opländer","doi":"10.1089/photob.2022.0005","DOIUrl":"https://doi.org/10.1089/photob.2022.0005","url":null,"abstract":"<p><p><b><i>Objective:</i></b> To determine effective treatment strategies against bacterial infections of burn wounds with <i>Pseudomonas aeruginosa</i>, we tested different treatment regimens with antibacterial blue light (BL). <b><i>Background:</i></b> Infections of burn wounds are serious complications and require effective and pathogen-specific therapy. Hereby, infections caused by <i>P. aeruginosa</i> pose a particular challenge in clinical practice due to its resistance to many antibiotics and topical antiseptics. <b><i>Methods:</i></b> LED-based light sources (450-460 nm) with different intensities and treatment times were used. Antibacterial effects against <i>P. aeruginosa</i> were determined by colony-forming unit (CFU) assays, human skin wound models, and fluorescence imaging. <b><i>Results:</i></b> In suspension assays, BL (2 h, 40 mW/cm², 288 J/cm²) reduced bacterial number (>5 log₁₀ CFU/mL). Applying 144 J/cm², using 40 mW/cm² for 1 h was more effective (>4 log₁₀ CFU) than using 20 mW/cm² for 2 h (>1.5 log₁₀ CFU). BL with low irradiance (24 h, 3.5 mW/cm², 300 J/cm²) only revealed bacterial reduction in thin bacteria-containing medium layers. In infected <i>in vitro</i> skin wounds only BL irradiation (2 h, 40 mW/cm², 288 J/cm²) exerted a significant antimicrobial efficacy (2.94 log₁₀ CFU/mL). <b><i>Conclusions:</i></b> BL treatment may be an effective therapy for <i>P. aeruginosa</i>-infected wounds to avoid radical surgical debridement. However, a significant antibacterial efficacy can only be achieved with higher irradiances and longer treatment times (min. 40 mW/cm²; >1 h), which cannot be easily integrated into regular clinical treatment protocols, for example, during a dressing change. Further studies are necessary to establish BL therapy for infected burns among tissue compatibility and interactions with previous therapeutic agents.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"40 12","pages":"800-809"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10335664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Combination of CO₂ Laser and Bifunctional Bonding Agents for Composite Resin Repairs After 1 Year of Aging.","authors":"Alexandre Morais,&nbsp;Pedro Henrique Cabral Oliveira,&nbsp;Luiz Henrique Cabral Oliveira,&nbsp;Ravana Angelini Sfalcin,&nbsp;Aldo Brugnera-Júnior,&nbsp;André Guaraci DeVito-Moraes,&nbsp;Maria Cristina Chavantes,&nbsp;Sandra Kalil Bussadori","doi":"10.1089/photob.2021.0133","DOIUrl":"https://doi.org/10.1089/photob.2021.0133","url":null,"abstract":"<p><p><b><i>Objective:</i></b> to evaluate the bond strength of repairs to composite resin restorations treated with CO₂ laser and bifunctional monomers after 1 year of aging. <b><i>Background:</i></b> Adequate bond strength between a composite restoration and resin repair agent can be achieved through mechanical and/or chemical treatment. However, the longevity of such repairs is unknown. <b><i>Methods:</i></b> Resin blocks (volume: 125 mm³) were created. Failure surfaces were either not treated or were treated before the repair with a universal adhesive, a silane bonding agent and/or CO₂ laser. The blocks were distributed into six groups (<i>n</i> = 6 per group): resin+resin group (RRG), universal adhesive+resin group (ARG), silane+universal adhesive group (SAG), laser+silane+universal adhesive group (LSAG), laser+universal adhesive group (LAG), and laser+silane group (LSG). After treatment, repairs were made with another resin composite. \"Sticks\" (1.0 mm² in area and 1.0 cm in length) were cut from the specimens in each group and immersed in distilled water at 37°C. Microtensile bond strength was evaluated after 1 year of aging. Bond strength values were compared using the Kruskal-Wallis test and Dunn's test. <b><i>Results:</i></b> Bond strength was significantly higher in the LSAG compared with the RRG, adhesive system, LSG, whereas statistically similar results were found for the SAG, LSAG, and LAG. Bond strength was lowest in the RRG. The LSAG and LAG presented predominantly cohesive fractures. <b><i>Conclusions:</i></b> The bond strength of composite resin repairs was satisfactory over time. Treatment with CO₂ laser contributed to the maintenance of bond strength during the 1-year storage period and bifunctional monomers present in the universal adhesive on the irradiated repair surface were of fundamental importance to the maintenance of bond strength values, as demonstrated by microtensile bond test and fracture pattern analysis.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"40 12","pages":"818-825"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10687688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}