Herman Roeykens, Peter De Coster, Wolfgang Jacquet, Roeland Jozef Gentil De Moor
{"title":"The Decisive Role of Laser Doppler Flowmetry for Pulp Preservation in Discolored Traumatized Teeth.","authors":"Herman Roeykens, Peter De Coster, Wolfgang Jacquet, Roeland Jozef Gentil De Moor","doi":"10.1089/photob.2020.4907","DOIUrl":"10.1089/photob.2020.4907","url":null,"abstract":"<p><p><b><i>Objective</i></b>: It has been stated that blood pigments within discolored teeth may interfere with Laser Doppler Flowmetry (LDF) measurements. The aim of this study was to assess pulp vitality with LDF in a cohort of discolored traumatized teeth referred for endodontic treatment or where the referring dentist had doubts regarding maintained tooth vitality. <b><i>Background:</i></b> Discoloration of teeth is a common sequel of dental trauma. Still today, it is taken as an indicator for root canal treatment. Transient apical breakdown (TAB) is confused with apical periodontitis, although it is a sequel of dental trauma in young mature teeth and will result in revascularization and dissolution of the apical radiolucency. <b><i>Methods:</i></b> A total of 26 patients with 28 discolored teeth, belonging to a cohort of referred patients with traumatized teeth referred for root canal treatment and/or pulp vitality assessment were screened on color with photographs by three investigators, with traditional sensibility tests and with a Moor VMS II LDF meter. <b><i>Results:</i></b> The color of the intrinsically discolored teeth was grayish in 58% of teeth, blue 20%, pink/crimson 12%, and yellow 4%. Eighty-five percent were central maxillary incisors, 11% were mandibulary incisors. Thanks to LDF, 43% of the trauma cases in this small cohort with discoloration underwent root canal treatment instead of 70% with traditional sensibility tests as indicator. TAB was found in 11%. <b><i>Conclusions:</i></b> LDF was decisive in diagnosing vitality of discolored teeth and there was no negative impact of tooth discoloration on LDF measurements.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"701-707"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25394231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modulatory Effects of 830 nm on Diabetic Wounded Fibroblast Cells: An In Vitro Study on Inflammatory Cytokines.","authors":"Tintswalo Nomsa Mgwenya,Heidi Abrahamse,Nicolette Nadene Houreld","doi":"10.1089/photob.2024.0041","DOIUrl":"https://doi.org/10.1089/photob.2024.0041","url":null,"abstract":"Background:After skin damage, a complicated set of processes occur for epidermal and dermal wound healing. This process is hindered under diabetic conditions, resulting in nonhealing diabetic ulcers. In diabetes there is an increase in inflammation and proinflammatory cytokines. Modulating cells using photobiomodulation (PBM) may have an effect on inflammation and cell viability, which are crucial for the healing of wounds. Objective: This study explored the impact of PBM in the near-infrared spectrum (830 nm; 5 J/cm2) on inflammation in diabetic wound healing. Materials and Methods: Five cell models, namely normal, wounded, diabetic, diabetic wounded, and wounded with d-galactose were used. Cell morphology and migration rate were assessed, while cellular response measures included viability (Trypan blue and adenosine triphosphate), apoptosis (annexin-V/PI), proinflammatory cytokines interleukin-6, tumor necrosis factor-alpha (TNF-α), and cyclooxygenase-2, nuclear translocation of nuclear factor kappa B (NF-κB), and gene expression of advanced glycation end product receptor (AGER). Results: PBM resulted in increased levels of TNF-α, supported by activation of NF-κB. PBM stimulated translocation of NF-κB and upregulation of AGER. Conclusions: PBM modulates diabetic wound healing in vitro at 830 nm through stimulated NF-κB signaling activated by TNF-α.","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142227891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatima Zanin, Gabriela Silva, E. Mayer-Santos, Ana Paula Brugnera, Ariane Sardop, Aldo Brugnera
{"title":"Er:YAG Laser and Hemolasertherapy: Bone and Gingiva Gain-Case Report.","authors":"Fatima Zanin, Gabriela Silva, E. Mayer-Santos, Ana Paula Brugnera, Ariane Sardop, Aldo Brugnera","doi":"10.1089/pho.2023.0138","DOIUrl":"https://doi.org/10.1089/pho.2023.0138","url":null,"abstract":"Background: Modern dentistry has increasingly valued conservative and biologically less invasive clinical practices, seeking to preserve the patients' tissues and natural dental elements. Most extractions in the dental clinic are preceded by periodontal disease that presents bone and gingival tissue loss, compromising the aesthetics as well as the support of dental elements. Objectives: The clinical approach in these cases often involves bone exertion followed by the successful installation of osseointegrated implants. Material and Methods: In this study, a case of extensive periodontal involvement and mobility of dental elements was carried out in a minimally invasive way, using the Er:YAG laser for periodontal decontamination and the hemolasertherapy technique to regenerate adjacent tissues, totaling nine weeks of treatment. Results: Clinical and radiographical improvement of tissue health and complete preservation of dental elements were observed. Conclusion: The patient underwent a follow-up appointment 2 years after the start of treatment when it was still possible to verify the stability of the clinical condition and the tissue gains obtained.","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140963543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acknowledgment of Reviewers 2023.","authors":"","doi":"10.1089/omi.2024.29107.ack","DOIUrl":"https://doi.org/10.1089/omi.2024.29107.ack","url":null,"abstract":"","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"44 2","pages":"186-187"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140521951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ya-Qun Kong, Xiao-Xi Dong, Ji-Zhi Zhao, Pu-Gen An, Yi-Zhou Li, Rui Ma, You-Jia Tang, Juan Liu, Meng-Lin Cheng, Qian Li
{"title":"The Use of 810 and 1064 nm Lasers on Dental Implants: <i>In Vitro</i> Analysis of Temperature, Surface Alterations, and Biological Behavior in Human Gingival Fibroblasts.","authors":"Ya-Qun Kong, Xiao-Xi Dong, Ji-Zhi Zhao, Pu-Gen An, Yi-Zhou Li, Rui Ma, You-Jia Tang, Juan Liu, Meng-Lin Cheng, Qian Li","doi":"10.1089/photob.2023.0069","DOIUrl":"10.1089/photob.2023.0069","url":null,"abstract":"Objective: The primary objective of this study was to evaluate the safety of 810 and 1064 nm laser treatment on dental implants. Background: Peri-implantitis is a challenge for clinicians and researchers. Methods: A pig mandible model was used to evaluate temperature increases during laser irradiation. Surface alterations on processed pure titanium discs were analyzed via scanning electron microscopy and measurement of surface contact angles. Processed titanium discs were cocultured in vitro with human gingival fibroblasts; subsequently, cell proliferation was measured. Results: The maximum temperature and time to reach each threshold were comparable. No surface alterations were detected after 810 nm laser irradiation, whereas surface cracks were observed after 1064 nm laser irradiation under the parameter setting of 31.84 W/cm2. Compared with unaltered processed pure titanium discs, the proliferation of human gingival fibroblasts was significantly greater on altered processed pure titanium discs. Conclusions: The use of either 810 or 1064 nm laser treatments may increase the risk of thermal damage in terms of increased temperature if the parameter setting is not warranted. In addition, the use of 1064 nm laser treatment could lead to changes in pure titanium discs that do not negatively affect cell proliferation. Further investigations of laser-assisted therapy are necessary to improve guidelines concerning the treatment of peri-implantitis. Clinical trial registration number: 2021-P2-098-01.","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"644-654"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10075522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Dentin and Zirconia Surface Treatments with Laser Irradiation Versus Sandblasting on the Bonding Ability of Zirconia.","authors":"Türker Akar, Gülşah İçen","doi":"10.1089/photob.2022.0154","DOIUrl":"10.1089/photob.2022.0154","url":null,"abstract":"<p><p><b><i>Objective:</i></b> This study aimed to investigate the effects of laser irradiation applied to zirconia and tooth surfaces on shear bond strength (SBS) compared with acid etching and sandblasting. <b><i>Background:</i></b> The effect of laser irradiation on the bond strength between zirconia and adhesives is a controversial issue for dentin surface treatments. In addition, the effects of different combinations of surface treatments to increase adhesion on both the zirconia and dentin surfaces remain unclear. <b><i>Materials and methods:</i></b> A total of 90 tooth samples were assigned into groups according to various pretreatments: control group was left untreated, acid etching, and Erbium, Chromium:Yttrium Scandium Gallium Garnet (Er,Cr:YSGG) laser irradiation group (15 Hz, 2 W). In addition, the zirconia specimens were separated into three groups (<i>n</i> = 10) according to the different surface treatments performed: sandblasting (120 μm Al<sub>2</sub>O<sub>3</sub>), Er,Cr:YSGG laser (15 Hz, 2 W), and as untreated surface. The zirconia samples were cemented to the dentin surface using dual-cure resin cement and subjected to an SBS test at a speed of 0.5 mm/min under a universal testing machine until fractures occurred in the bonding surface. <b><i>Results:</i></b> The highest SBS values were observed in Group tooth acid (TA)-zirconia Er,Cr:YSGG laser (ZL), followed by Group tooth Er,Cr:YSGG laser (TL)-zirconia sandblasting (ZS) and Group TA-zirconia control (ZC). The lowest SBS values were found in Group TA-ZS. Significant intergroup difference was noted between Group TA-ZL, Group tooth control (TC)-ZC, Group TL-ZS, and Group TC-ZC. However, no significant difference was noted between Group TA-ZL, Group TL-ZS, and Group TA-ZC. <b><i>Conclusions:</i></b> Acid etching and laser treatments applied to the dentin and zirconia surfaces were found to be effective techniques for improving the zirconia-dentin bond, respectively. Clinical Trial Registration number: 33216249-604.01.02-E.24308.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"501-508"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10184683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Domenico Piccolo, Laura Pieri, Irene Fusco, Giustino Gallo, Paolo Bonan
{"title":"Removal of Unwanted Hair: Efficacy and Safety of 755-nm Alexandrite Laser Equipped with a 30 mm Spot Handpiece.","authors":"Domenico Piccolo, Laura Pieri, Irene Fusco, Giustino Gallo, Paolo Bonan","doi":"10.1089/photob.2023.0067","DOIUrl":"10.1089/photob.2023.0067","url":null,"abstract":"<p><p><b><i>Background:</i></b> Alexandrite 755 nm laser has been currently recognized one of the gold standards for the permanent hair removal business because of its sufficient tissue penetration and higher affinity for melanin compared with Nd:YAG, making the treatment more incisive and effective. <b><i>Objective:</i></b> In this study, we evaluated an Alexandrite 755 nm laser with a 30-mm spot for a new and fast hair removal treatment. <b><i>Methods:</i></b> Patients of both genders, with skin Fitzpatrick's types, ranging from II to III, were asked to avoid any epilation techniques 4 weeks before the laser hair removal session. Participants underwent a minimum of three to a maximum of eight sessions of treatment, every 6 weeks. Six months after the last treatment, the final evaluation was completed. The treated body areas included arms, legs, axillae, and trunk. The subjects used a numeric scale with a range of 0 to 10 (0: no pain, 10: unbearable), to indicate the associated pain level experienced. By comparing the percentage of terminal hairs before and after laser treatment, hair reduction was determined. <b><i>Results:</i></b> The patients reported only slight post-treatment erythema that disappeared after a few hours and only two patients showed persistent erythema lasting a few weeks. The pain was found to be 4.9 ± 0.9 after single pass emission. <b><i>Conclusions:</i></b> The 755 nm laser with the new handpiece has proven to be an ideal wavelength for hair removal, allowing efficient, safe, and faster treatments to be performed for the patient.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"509-511"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10210872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Transcranial Photobiomodulation on Depressive Symptoms: A Meta-Analysis.","authors":"Yoonju Cho, Umit Tural, Dan V Iosifescu","doi":"10.1089/photob.2023.0041","DOIUrl":"10.1089/photob.2023.0041","url":null,"abstract":"<p><p><b><i>Background:</i></b> Transcranial photobiomodulation (tPBM) is a novel, noninvasive, device-based intervention, which has been tested as a possible treatment for various neurological and psychiatric conditions. Recently, it has been investigated as an innovative treatment for major depressive disorder (MDD). There have been several animal and clinical studies that evaluated the underlying mechanism and the efficacy of its antidepressant effects, but results have been conflicting. <b><i>Objective:</i></b> Thus, we conducted the first meta-analysis on effects of tPBM on depressive symptoms. <b><i>Materials and methods:</i></b> Thirty original articles on tPBM were retrieved, eight of them met criteria for inclusion to a random effects meta-analysis. <b><i>Results:</i></b> tPBM appeared effective in decreasing depressive symptom severity regardless of diagnosis (Hedges' <i>g</i> = 1.415, <i>p</i> < 0.001, <i>k</i> = 8), but a significant heterogeneity has been found. The meta-analysis of single-arm studies (baseline to endpoint changes) limited to participants with MDD has supported the significant effect of tPBM in reducing the depression severity, without a significant heterogeneity (Hedges' <i>g</i> = 1.142, 95% confidence interval = 0.780-1.504, <i>z</i> = 6.19, <i>p</i> < 0.001, <i>k</i> = 5). However, the meta-analysis of the few double-blind, sham-controlled studies in MDD has not supported the statistically significant superiority of tPBM over sham (Hedges' <i>g</i> = 0.499, <i>p</i> = 0.211, <i>k</i> = 3), although a sample size bias is likely present. <b><i>Conclusions:</i></b> Overall, this meta-analysis provides weak support for the promising role of tPBM in the treatment of depressive symptoms. Dose finding studies to determine optimal tPBM parameters followed by larger, randomized, sham-controlled studies will be needed to fully demonstrate the antidepressant efficacy of tPBM.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"460-466"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10184678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liangzhe Li, Jiayan Chen, Guanghao Qin, Yifan Qi, Yimeng Chen, Mingze Li, Qing Zhang, Yuan Cheng, Naici Guo, Salissou Moutari, Jonathan E Moore, Sile Yu, Xingru He, Emmanuel Eric Pazo
{"title":"Tear Film Lipid Layer Changes Following Combined Effect of Heated Eye Mask with Intense Pulsed Light Therapy for Evaporative Dry Eye: A Randomized Control Study.","authors":"Liangzhe Li, Jiayan Chen, Guanghao Qin, Yifan Qi, Yimeng Chen, Mingze Li, Qing Zhang, Yuan Cheng, Naici Guo, Salissou Moutari, Jonathan E Moore, Sile Yu, Xingru He, Emmanuel Eric Pazo","doi":"10.1089/photob.2023.0051","DOIUrl":"https://doi.org/10.1089/photob.2023.0051","url":null,"abstract":"<p><p><b><i>Background:</i></b> Dry eye disease (DED) is a complex ocular surface inflammatory disorder with a multifactorial etiology. Therapies such as intense pulsed light (IPL) and heated eye mask (HEM) have been reported to improve the tear film lipid layer (TFLL) and signs and symptoms of DED. <b><i>Methods:</i></b> This randomized study aimed to compare the effects of IPL combined with HEM (IPL+HEM) group, IPL group, and control group in participants with evaporative DED. All participants were examined at baseline (D0), day 21 (D21), day 42 (D42), and day 84 (D84) for noninvasive tear breakup time (NITBUT), TFLL, corneal conjunctival staining (CS), meibomian gland quality (MGQ), meibomian gland expressibility (MGEx), and Ocular Surface Disease Index (OSDI). <b><i>Results:</i></b> The mean age of participants was IPL+HEM: 28.06 ± 3.88 years, IPL: 29.88 ± 4.68 years, and control: 28.52 ± 3.77 years. At D84, significant improvements in TFLL (<i>p</i> < 0.05), noninvasive tear breakup time (NITBUT) (<i>p</i> < 0.05), corneoconjunctival staining (CS) (<i>p</i> < 0.05), MGQ (<i>p</i> < 0.05), MGEx (<i>p</i> < 0.05), and OSDI (<i>p</i> < 0.05) were found in the IPL+HEM and IPL groups, whereas the control group had no significant improvements. Furthermore, ΔTFLL significantly correlated with ΔNITBUT (<i>r</i> = -0.678, <i>p</i> < 0.001), ΔCS (<i>r</i> = 0.321, <i>p</i> < 0.001), ΔMGQ (<i>r</i> = 0.669, <i>p</i> < 0.001), ΔMGEx (<i>r</i> = 0.598, <i>p</i> < 0.001), and ΔOSDI score (<i>r</i> = 0.649, <i>p</i> < 0.001). <b><i>Conclusions:</i></b> IPL therapy in combination with HEM and IPL therapy only can significantly improve the quality of TFLL and clinically reduce the sign and symptoms of evaporative DED. However, IPL therapy in combination with HEM was found to be more effective than IPL therapy alone.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 8","pages":"435-444"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460692/pdf/photob.2023.0051.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10476459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}