Photobiomodulation, photomedicine, and laser surgery最新文献

{"title":"Photobiomodulation Literature Watch November 2022.","authors":"James D Carroll","doi":"10.1089/photob.2023.0042","DOIUrl":"https://doi.org/10.1089/photob.2023.0042","url":null,"abstract":"","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 4","pages":"193-197"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9752349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extended Application of Fractional Carbon Dioxide Laser in the Treatment of Port Wine Stain Birthmarks with Hypertrophy: A Case Report.","authors":"Tingwei Zhang","doi":"10.1089/photob.2022.0149","DOIUrl":"https://doi.org/10.1089/photob.2022.0149","url":null,"abstract":"<p><p><b><i>Background:</i></b> Conventional treatments of port wine stain birthmarks often do not achieve the desired outcome in patients with hypertrophy. Potential reasons include deeper and larger blood vessels, abnormal arrangement of blood vessels, and darker or thicker epidermis. However, these factors may not significantly limit the efficacy of fractional carbon dioxide (CO₂) laser. The aim of this case report was to examine the extended application of fractional CO₂ laser in treating patients with hypertrophic port wine stain birthmarks. <b><i>Methods:</i></b> Two cases with hypertrophic port wine stain birthmarks treated with fractional CO₂ laser for 5 years are described in this case report. <b><i>Results:</i></b> When compared with conventional treatment, both cases reported better outcomes, including a reduced risk of infection, pigmentation, and scarring, a decrease of clinical erythema, and much less pain. <b><i>Conclusions:</i></b> The findings demonstrate that fractional CO₂ laser has the potential to be an effective modality for the treatment of patients with hypertrophic port wine stains.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 4","pages":"189-192"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10295352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-Intensity Visible and Near-Infrared Light-Induced Cell Signaling Pathways in the Skin: A Comprehensive Review.","authors":"Augustin C Barolet,&nbsp;Amelia M Villarreal,&nbsp;Abdulhadi Jfri,&nbsp;Ivan V Litvinov,&nbsp;Daniel Barolet","doi":"10.1089/photob.2022.0127","DOIUrl":"https://doi.org/10.1089/photob.2022.0127","url":null,"abstract":"<p><p><b><i>Objective:</i></b> To describe current knowledge regarding established and putative cell signaling pathways involved in skin photobiomodulation. <b><i>Background:</i></b> The skin is the largest and most accessible organ of the body. It is the first line of defense against the external environment, including solar radiation. Among solar rays, visible and infrared non-ionizing photons may reach human skin and trigger a cascade of non-thermal cell signaling pathways called photobiomodulation (PBM). The use of PBM using artificial light sources has been known for more than 50 years, but it has not yet been widely accepted due to uncertainty about the cellular mechanisms of action. However, much knowledge has been gained in this field in recent years, which will be summarized in this review. <b><i>Methods:</i></b> An extensive literature review was performed using Medline, Embase, and Google Scholar as research databases to acquire relevant publications in this particular field. <b><i>Results:</i></b> A comprehensive description of chromophores, primary and secondary effectors is provided in addition to a visual representation of known and putative cell signaling mechanisms involved in such complex light-skin interactions. Also, a summary of clinical indications of skin PBM, key light parameters, and promising skin applications (local and systemic) are mentioned. <b><i>Conclusions:</i></b> In PBM, skin cells are the first to absorb photons, triggering specific cell-signaling pathways through primary and secondary effectors, leading to enhanced cell repair and survival, notably in hypoxic or stressed cells. A better understanding of the mechanisms of action will help us optimize known indications and discover new ones.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 4","pages":"147-166"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9383786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontal, Microbiological, and Proinflammatory Cytokines Levels in Fixed Orthodontics Patients Treated with Photodynamic Therapy Adjunct to Full Mouth Scaling.","authors":"Ali Alqerban,&nbsp;Saeed N Asiri,&nbsp;Rawda Alghabban,&nbsp;Fahad Alharbi,&nbsp;Abdullah Almalki,&nbsp;Ali S Aljhani,&nbsp;Ferdous Bukhary,&nbsp;Rawa Abdelrahim,&nbsp;Fahad Alkhtani,&nbsp;Abdulaziz Samran","doi":"10.1089/photob.2022.0155","DOIUrl":"https://doi.org/10.1089/photob.2022.0155","url":null,"abstract":"<p><p><b><i>Objective:</i></b> To assess the efficiency of photodynamic therapy (PDT) adjunct to full mouth scaling (FMS) in improving periodontal, microbiological, and proinflammatory cytokines levels in patients undergoing fixed orthodontics treatment (FOT). <b><i>Materials and methods:</i></b> The study recruited 60 teenage patients who were undergoing FOT. All the patients were arbitrarily divided into two groups: Group 1, FMS +PDT and Group 2, FMS alone. Plaque scores (PS), bleeding on probing (BOP), and probing depth (PD) were assessed. Levels of biomarkers interleukin (IL)-6 and tumor necrosis factor-alpha (TNF-α) using enzyme-linked immunosorbent assay were evaluated. Samples were collected from gingival plaque for estimation of <i>Prevotella intermedia</i> and <i>Porphyromonas gingivalis</i> load. All measurements were completed at three intervals baseline, 4th week, and 8th week. Post Hoc corrections and intergroup comparisons were examined using Student's <i>t</i>-test and Bonferroni correction. To find differences between repeated follow-ups, analysis of variance (ANOVA) multiple rank tests were used. <b><i>Results:</i></b> At baseline, all the gingival parameters displayed comparable outcomes between patients of Group 1 and Group 2 (<i>p</i> > 0.05). However, at 4 and 8 weeks of follow-up, PS and BOP among tested groups exhibited significantly lower values than baseline (<i>p</i> < 0.001). At 8 weeks, there was a significant difference in PS between the two groups tested. Moreover, at 4 and 8 weeks, BOP revealed a significant difference between the groups. PD remains comparable with baseline at follow-up visits (<i>p</i> > 0.05). A significant decrease in IL-6 and TNF-α levels was observed in both investigated groups at 4 and 8 weeks of baseline. Moreover, it was identified that <i>P. intermedia</i> and <i>P. gingivalis</i> were reduced significantly at 4 weeks. Moreover, a significant difference existed between both Group 1 and Group 2 at 4 and 8 weeks of recall visit (<i>p</i> < 0.05). <b><i>Conclusions:</i></b> The use of photodynamic treatment adjuvant to FMS aids in improving periodontal parameters and cytokines levels.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 3","pages":"133-139"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9132933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Portable 445 nm Laser Versus Intense Pulsed Light Treatment for Dry Eye: A Prospective Randomized Pilot Study.","authors":"Pieter Gouws,&nbsp;Stephen Barabas,&nbsp;Alexander Gouws","doi":"10.1089/photob.2022.0102","DOIUrl":"https://doi.org/10.1089/photob.2022.0102","url":null,"abstract":"<p><p><b><i>Objective:</i></b> The aim of the study is to evaluate the efficacy of intense pulsed light (IPL) compared with a portable 445 nm laser device in the treatment of dry eye. Our hypothesis was that IPL and 445 nm laser can provide equal reduction of symptoms for patients with dry eye disease. <b><i>Methods:</i></b> Participants provided written informed consent as per the Helsinki declaration before a baseline testing (visit 1). All participants completed four in-clinic study visits and one telephone call over the course of ∼4 months. The patients were evaluated at baseline and received the first treatment (visit 1) at the same visit. Thereafter, treatment was repeated every 2 weeks until four treatments had been administered (visits 2-4). The evaluation of dry eye included the following tests for both eyes: tear break-up time (TBUT), in seconds, taken in three measurements using a timer; corneal fluorescein staining (CFS); and lissamine green (grading 0-5 as per Oxford grading system). Other tests included visual acuity and the measurement of intraocular pressure. A full medical history and current ocular and systemic medications were obtained. All participants completed the Dry Eye Questionnaire (DEQ5), as per DEWS II, at each visit, as well as during the final telephone assessment ∼2 months after their fourth treatment. <b><i>Results:</i></b> Twenty-eight eyes of 14 patients were included in the study. The eyes were randomized with 14 eyes in each group receiving either 445 nm laser or IPL. The group included 10 female and 4 male participants with average age of 64.8 years (standard deviation 13.9). The primary outcome measures of TBUT, CFS, and the DEQ5 questionnaire were statistically significantly improved. TBUT IPL versus 445 nm laser <i>p</i> = 0.0097 versus 0.0115, CFS IPL versus 445 nm laser <i>p</i> = 0.0027 versus 0.0003. The questionnaire did not discriminate between the two methods but also showed highly statistically significant improvement <i>p</i> = 0.0001. <b><i>Conclusions:</i></b> The portable 445 nm laser and IPL were equally effective in the treatment of dry eye in this cohort. No significant adverse events were noted in either treatment group. K-Laser Blue^® can be considered as a substitute for IPL treatment for dry eye.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 3","pages":"120-124"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9317441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Tumor Volume on the Fluence Rate Within Human Breast Model Using Continuous-Wave Diffuse Optical Imaging: A Simulation Study.","authors":"Shimaa Mahdy,&nbsp;Omnia Hamdy,&nbsp;Mohamed A A Eldosoky,&nbsp;Mohammed A Hassan","doi":"10.1089/photob.2022.0100","DOIUrl":"https://doi.org/10.1089/photob.2022.0100","url":null,"abstract":"<p><p><b><i>Objective:</i></b> This article investigates the effect of varying breast tumor size on the fluence rate distribution within a breast model during the diffuse optical imaging procedure. <b><i>Background:</i></b> Early detection of breast cancer is of significant importance owing to its wide spread among women worldwide. Mastectomy surgery became very common due to the late detection of breast cancers by the conventional diagnostic methods such as X-ray mammography and magnetic resonance imaging. On the contrary, optical imaging techniques provide a safe and more sensitive methodology, which is suitable for the early detection criteria. <b><i>Methods:</i></b> The implementation was performed based on simulating multiple detectors placed on the outer surface of a human breast model to compute the optical fluence rate after probing the breast (normal and different tumor sizes) with laser irradiation. Different laser wavelengths ranging from the red to near-infrared rays spectral range were examined to determine the optimum fluence rate that shows the highest capability to differentiate between normal and cancerous breasts. A three-dimensional breast model was created using the COMSOL multiphysics package where the optical fluence rate was estimated based on the finite-element solution of the diffusion equation. <b><i>Results:</i></b> To evaluate the efficiency of the suggested technique for identifying cancers and discriminate them from normal breast at various wavelengths (600-1000 nm) and several tumor sizes. <b><i>Conclusions:</i></b> The obtained results reveal different fluence rate distributions in the breast with different radius tumors, especially at 600 nm due to the significant differences in the scattering coefficient between malignancies and healthy tissue.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 3","pages":"125-132"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9132932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitochondrial Transplantation: Could Photobiomodulation Play a Role?","authors":"Michael R Hamblin","doi":"10.1089/photob.2023.0012","DOIUrl":"https://doi.org/10.1089/photob.2023.0012","url":null,"abstract":"","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 3","pages":"91-92"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9201801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photobiomodulation Literature Watch October 2022.","authors":"James D Carroll","doi":"10.1089/photob.2023.0026","DOIUrl":"https://doi.org/10.1089/photob.2023.0026","url":null,"abstract":"","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 3","pages":"140-143"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9195806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review of Applications and Intracellular Mechanisms of Intense Pulsed Light in Eyelid Inflammatory Diseases.","authors":"Hongya Zeng,&nbsp;Lan Gong","doi":"10.1089/photob.2022.0120","DOIUrl":"https://doi.org/10.1089/photob.2022.0120","url":null,"abstract":"<p><p><b><i>Objective:</i></b> To evaluate relevant clinical outcomes and conclude possible mechanisms of intense pulsed light (IPL) in eyelid inflammation. <b><i>Background:</i></b> IPL devices were primarily applied in cutaneous vascular malformations and have been used in ocular diseases for about 20 years, mostly including meibomian gland dysfunction (MGD), blepharitis, and ocular rosacea. <b><i>Recent findings:</i></b> Seventy-two original clinical researches were included, 57 for MGD, 4 for blepharitis or blepharitis-related keratoconjunctivitis, and 11 for rosacea. Dry eye symptoms, (tear) break-up time (BUT), and meibomian structure and/or functions were improved in most patients, but production of reactive oxygen species is an important link in the photobiomodulation mediated by IPL, which can influence numerous signal pathways to achieve anti-inflammatory, anti-infective, and prodifferentiation effects. <b><i>Conclusions:</i></b> The evidence suggests that IPL is an effective therapeutic tool for most patients with MGD, but more clinical evidence is needed for other indications.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 3","pages":"104-119"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9132931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Titanium Implant Stability with Photobiomodulation: A Review and Meta-Analysis of Irradiation Parameters.","authors":"Dennis Sourvanos, Jason Poon, Bradley Lander, Hector Sarmiento, James Carroll, Timothy C Zhu, Joseph P Fiorellini","doi":"10.1089/photob.2022.0161","DOIUrl":"10.1089/photob.2022.0161","url":null,"abstract":"<p><p><b><i>Objective:</i></b> This analysis was designed to present a summary of available evidence that will inform practice and guide future research for photobiomodulation (PBM) after titanium implant placement procedures. <b><i>Materials and methods:</i></b> A systematic review was performed according to the Cochrane Collaboration and in line with Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) criteria. Two investigators screened the titles and abstracts, and reviewed articles for risk of bias. Online databases searched included PubMed, Embase, Scopus, and Web of Science. Terms were specific to the effects of PBM on dental implant stability. <b><i>Results:</i></b> Eight hundred fifty-six studies were identified, and 15 studies fulfilled the inclusion criteria. Light sources included both laser and light emitting diode (LED) devices. Wavelengths ranged from 618 to 1064 nm. The meta-analysis concluded that all 15 published studies were able to safely apply PBM near dental implants without adverse events. Laser and LED wavelengths that reported significant results included 618, 626, 830, 940 (2 × ), and 1064 nm. <b><i>Conclusions:</i></b> The use of adjunctive PBM can be safely prescribed after surgical placement of titanium implants. Six groups reported statistical significance for improving implant stability (four laser diode, two LED) in wavelengths ranging from 618 to 1064 nm. The amount of time spent delivering PBM was not a variable that differentiated whether a study reported significant results.</p>","PeriodicalId":20111,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"41 3","pages":"93-103"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9139165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}