Physiological Reports最新文献

Relationship between primitive reflexes, functional fitness, handgrip strength, and physical activity in older adults aged 65 and over.

IF 2.2

Physiological Reports Pub Date : 2025-04-01 DOI: 10.14814/phy2.70229

Erzsébet Stephens-Sarlós, Anna Horváth-Pápai, Eliza E Tóth, Ferenc Ihász, Angéla Somogyi, Attila Szabo

{"title":"Relationship between primitive reflexes, functional fitness, handgrip strength, and physical activity in older adults aged 65 and over.","authors":"Erzsébet Stephens-Sarlós, Anna Horváth-Pápai, Eliza E Tóth, Ferenc Ihász, Angéla Somogyi, Attila Szabo","doi":"10.14814/phy2.70229","DOIUrl":"10.14814/phy2.70229","url":null,"abstract":"The reemergence of primitive reflexes (PRs) in older adults is associated with dementia and cognitive impairment. Recent experimental work suggests gentle sensorimotor exercises may halt or reverse PR's inverse development. These findings question whether physical activity (PA) is negatively related to PRs. This study aimed to test this relationship in 52 older adults aged 66 and over who were volunteers from seven Hungarian nursing homes. They were tested individually using the Senior Test, hand-grip strength, 13 PRs, and PA levels using the Global Physical Activity Questionnaire. Apart from upper and lower body flexibility, all functional fitness indices and PA were negatively related to the number of PRs. A bootstrapped multiple hierarchical linear regression revealed that only PA was a statistically significant predictor (p < 0.001) of the PRs, accounting for 41% of the variance. This study is the first to demonstrate a robust negative relationship between PA and PRs and a weak negative association with hand-grip strength and four elements of functionality in older adults. The implications of the results could be significant for developing interventions to prevent or delay PRs' inverse development, which is associated with adverse mental health in older adults.","PeriodicalId":20083,"journal":{"name":"Physiological Reports","volume":"13 7","pages":"e70229"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex differences in middle cerebral artery reactivity and hemodynamics independent from changes in systemic arterial stiffness in Sprague-Dawley rats.

IF 2.2

Physiological Reports Pub Date : 2025-04-01 DOI: 10.14814/phy2.70250

Jonathan W Ray, Xuming Sun, Nildris Cruz-Diaz, Victor M Pulgar, Liliya M Yamaleyeva

{"title":"Sex differences in middle cerebral artery reactivity and hemodynamics independent from changes in systemic arterial stiffness in Sprague-Dawley rats.","authors":"Jonathan W Ray, Xuming Sun, Nildris Cruz-Diaz, Victor M Pulgar, Liliya M Yamaleyeva","doi":"10.14814/phy2.70250","DOIUrl":"10.14814/phy2.70250","url":null,"abstract":"The mechanisms of sex differences in cerebrovascular function are not well understood. In this study, we determined whether sex differences in middle cerebral artery (MCA) reactivity are accompanied with changes in cerebral or systemic arterial resistance and stiffness in young adult Sprague-Dawley (SD) rats. No differences in systolic or diastolic blood pressures were observed between sexes. Heart rate was higher in the female versus male SD. Left MCA pulsatility index (PI) was lower in female versus male SD. No differences in left intracranial internal carotid artery (ICA) PI were observed between sexes. There were no differences in thoracic aorta or left common carotid artery pulse wave velocity (PWV) between sexes. In isolated MCA segments, female left MCA had lower contraction to potassium, but similar maximal contraction and sensitivity to thromboxane A2 receptor agonist U46619. Pre-incubation with indomethacin lowered maximal response and sensitivity to U46619 in male but not female MCA. Endothelial nitric oxide synthase and vascular smooth muscle layer thromboxane A2 receptor immunoreactivity were greater in female versus male SD. We conclude that sex differences in the MCA reactivity are associated with a differential functional profile of MCA in adult SD rats independent from changes in systemic PWV.","PeriodicalId":20083,"journal":{"name":"Physiological Reports","volume":"13 7","pages":"e70250"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11959158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neural indicators of sleep loss and sleep propensity in male military trainees: Insights from dry-electrode EEG-An exploratory study.

IF 2.2

Physiological Reports Pub Date : 2025-04-01 DOI: 10.14814/phy2.70301

Jazmin Morrone, Sarah Coakley, Sam Blacker, Stephen Myers, Paul Hough, Christopher Vine, Tessa Maroni, Neil Stanley, Shona Halson, Andrew Siddall, Stephen Patterson, Martin Jones, Kieran Chillingsworth, Charles R Pedlar

{"title":"Neural indicators of sleep loss and sleep propensity in male military trainees: Insights from dry-electrode EEG-An exploratory study.","authors":"Jazmin Morrone, Sarah Coakley, Sam Blacker, Stephen Myers, Paul Hough, Christopher Vine, Tessa Maroni, Neil Stanley, Shona Halson, Andrew Siddall, Stephen Patterson, Martin Jones, Kieran Chillingsworth, Charles R Pedlar","doi":"10.14814/phy2.70301","DOIUrl":"https://doi.org/10.14814/phy2.70301","url":null,"abstract":"This study examined the impact of reduced sleep on electroencephalogram (EEG) activity during cognitive tasks in Military Clearance Diver trainees using a novel dry-electrode EEG system. Seven male participants underwent two 5-day periods: a baseline and a \"live-in\" phase with increased workload and reduced sleep (5.4 ± 0.1 vs. 7.4 ± 0.7 h). EEG was recorded daily in the early morning (am) and late afternoon (pm) during a Psychomotor Vigilance Test (PVT), two oculography tests (am: n = 4; pm: n = 3), and 2 min of eyes-closed rest. Significant increases in theta (t (29) = 2.308, p = 0.028, d = 0.421) and alpha (t (29) = 2.124, p = 0.042, d = 0.388) power spectrum densities were observed in the \"live-in\" phase during the PVT. These findings align with increased lower frequency activity over time awake, reflecting heightened sleep propensity. Sleep loss was further confirmed by declining Odds Ratio Product (ORP) values. This study demonstrates the feasibility of dry-electrode EEG in detecting fatigue-related neural changes and highlights the potential of ORP as a quantifiable fatigue marker. These insights may inform operational settings, such as military diver performance monitoring and fatigue management strategies.","PeriodicalId":20083,"journal":{"name":"Physiological Reports","volume":"13 7","pages":"e70301"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

African Americans with a family history of cardiovascular disease show lower endothelial-dependent vasodilation.

IF 2.2

Physiological Reports Pub Date : 2025-04-01 DOI: 10.14814/phy2.70176

Julian F Thayer, Darcianne K Watanabe, Julia Birenbaum, Julian Koenig, Marc Jarczok, DeWayne P Williams, Gaston K Kapuku

{"title":"African Americans with a family history of cardiovascular disease show lower endothelial-dependent vasodilation.","authors":"Julian F Thayer, Darcianne K Watanabe, Julia Birenbaum, Julian Koenig, Marc Jarczok, DeWayne P Williams, Gaston K Kapuku","doi":"10.14814/phy2.70176","DOIUrl":"10.14814/phy2.70176","url":null,"abstract":"Normotensive African Americans (AAs) show attenuated vascular responses and reduced nitric oxide (NO) bioavailability compared to European Americans (EAs). Few studies have used diverse measures to examine differences in macrovascular function and structure in individuals with a family history of CV disease (CVD). We assessed 150 AAs (Mage, 23.57 ± 2.73 yr) and 104 EAs (Mage, 22.70 ± 2.86) with a confirmed family history of CVD. Age, sex, body mass index, and father's education were used as covariates, hemodynamic measures (heart-rate [HR], stroke volume [SV], cardiac output [CO], total peripheral resistance [TPR], mean arterial pressure [MAP], systolic and diastolic blood pressure [SBP/DBP], and pulse pressure [PP]), high-frequency heart-rate variability [HF-HRV], and endothelial-dependent arterial dilation [EDAD] were the dependent variables. AA's had lower EDAD (11.64 vs. 13.20%) and higher HF-HRV (7.31 vs. 7.11 ms2), TPR (17.60 vs. 15.93 mmHg/L/min), TPI (33.72 vs. 30.09 mmHg/L/min/m2), MAP (83.60 vs. 78.36 mmHg), SBP (115.44 vs. 110.23 mmHg), and DBP (65.35 vs. 60.57 mmHg). Lower EDAD alongside no ethnic differences in PP, HR, or SV suggests early onset endothelial dysfunction (lower NO availability) rather than inherited pathophysiological structural characteristics (arterial stiffness) in AAs. Future prospective studies are needed and should consider measures of sympathetic activity and potential moderators, including discrimination.","PeriodicalId":20083,"journal":{"name":"Physiological Reports","volume":"13 7","pages":"e70176"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of body composition, cardiorespiratory, and neuromuscular adaptations induced by three different high intensity training protocols.

IF 2.2

Physiological Reports Pub Date : 2025-04-01 DOI: 10.14814/phy2.70306

Corentin Scoubeau, Julie Carpentier, Stéphane Baudry, Vitalie Faoro, Malgorzata Klass

{"title":"Comparison of body composition, cardiorespiratory, and neuromuscular adaptations induced by three different high intensity training protocols.","authors":"Corentin Scoubeau, Julie Carpentier, Stéphane Baudry, Vitalie Faoro, Malgorzata Klass","doi":"10.14814/phy2.70306","DOIUrl":"10.14814/phy2.70306","url":null,"abstract":"This study investigated body composition, cardiorespiratory, and neuromuscular adaptations induced by three high intensity trainings easy to fit into daily routine. Thirty-seven adults participated in one of the following 8-week interventions: vigorous intensity continuous training (VICT; 28 min at 70% of peak oxygen uptake [VO2peak]), long interval high intensity interval training (LI-HIIT; 6 × 2 min at 85% VO2peak), or short interval HIIT (SI-HIIT; 12 × 30 s at 125% maximal power output). Heart rate (HR) and rating of perceived exertion (RPE) were measured during sessions. Pre- and post-intervention assessments included fat and lean mass, cardiopulmonary exercise testing, knee extensors maximal isometric torque, voluntary activation, and endurance during a submaximal contraction. Compared to SI-HIIT and VICT, LI-HIIT sessions were characterized by a shorter duration, a similar time spent above 90% HRmax, but a higher RPE (p < 0.05). VO2peak and muscle endurance increased respectively by 14% and 12%, while knee extensors torque, voluntary activation, and lean mass increased to a lesser extent (1%-3%) after the interventions (ANOVA time-effect, all p < 0.05). There was no significant difference between the modalities (intervention × time interaction, all p > 0.05). In conclusion, comparable body composition, cardiorespiratory, and neuromuscular adaptations were induced by the three high intensity training protocols, while RPE was higher during LI-HIIT sessions.","PeriodicalId":20083,"journal":{"name":"Physiological Reports","volume":"13 7","pages":"e70306"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11962203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inspiratory and expiratory sinus arrhythmia in healthy human. 健康人的吸气和呼气窦性心律失常。

IF 2.2

Physiological Reports Pub Date : 2025-04-01 DOI: 10.14814/phy2.70245

Pascale Calabrese, Sophie Lambert-Lacroix

{"title":"Inspiratory and expiratory sinus arrhythmia in healthy human.","authors":"Pascale Calabrese, Sophie Lambert-Lacroix","doi":"10.14814/phy2.70245","DOIUrl":"10.14814/phy2.70245","url":null,"abstract":"Breathing and ECG were recorded in 33 healthy human subjects at rest. The RR interval was labeled according to its occurrence in the respiratory phases: II (both R waves during inspiration), IE (first R wave in inspiration and following R wave in expiration), EE (both R waves during expiration), and EI (first R wave in expiration and following R wave in inspiration). For each subject, II and EE intervals were plotted versus normalized mean inspiratory duration and normalized mean expiratory duration, respectively, and correlation coefficients and slopes of regression lines were calculated. Statistical analyses were conducted to compare these slopes between and within individuals. These relationships appeared to be linear in most cases, although neither the decrease nor the increase in heart rate occurred at the same rate for all subjects. Overall, the slope associated with II intervals was not higher, in terms of absolute values, than the slope associated with EE intervals for the same subject. Our results underscore the difference between inspiratory and expiratory sinus arrhythmia and suggest that the effects of any stimulation presumed to induce changes in vagal cardiac activity should primarily be sought during expiration.","PeriodicalId":20083,"journal":{"name":"Physiological Reports","volume":"13 7","pages":"e70245"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11963900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of blood flow restriction cuff design on upper body exercise: A randomized crossover trial in resistance-trained adults.

IF 2.2

Physiological Reports Pub Date : 2025-04-01 DOI: 10.14814/phy2.70303

Nicholas Rolnick, Victor S de Queiros, Brent Fedorko, Samantha Watson, Campbell Ruffhead, Sean Zupnik, Lucas Kuriawa, Mark Weedon, Tim Werner

{"title":"Impact of blood flow restriction cuff design on upper body exercise: A randomized crossover trial in resistance-trained adults.","authors":"Nicholas Rolnick, Victor S de Queiros, Brent Fedorko, Samantha Watson, Campbell Ruffhead, Sean Zupnik, Lucas Kuriawa, Mark Weedon, Tim Werner","doi":"10.14814/phy2.70303","DOIUrl":"10.14814/phy2.70303","url":null,"abstract":"Differences in cuff blood flow restriction (BFR) bladder design (single-chambered [SC-BFR] and multi-chambered [MC-BFR] systems) may influence exercise performance, perceptual responses, and cardiovascular outcomes. In a randomized cross-over design, twenty-six healthy physically active individuals (22.6 ± 5.5 years old, 10 females; 25 reported engaging in resistance-exercise consistently) performed four sets of bilateral biceps curls to volitional failure using 20% of the 1-repetition maximum under three conditions: SC-BFR, MC-BFR, and a non-BFR control, post-exercise perceptual responses, and cardiovascular measures pre- and post-exercise. SC-BFR significantly reduced total repetitions compared to MC-BFR and N-BFR (p < 0.001). MC-BFR and N-BFR conditions demonstrated comparable performance in later sets. RPD was significantly higher in SC-BFR compared to MC-BFR and N-BFR (p < 0.001), while MC-BFR elicited lower RPE than SC-BFR (p = 0.025). Both SC-BFR and N-BFR conditions significantly reduced post-exercise diastolic blood pressure and mean arterial pressure, whereas MC-BFR did not. No significant differences in PWV were observed across conditions. SC-BFR induces greater repetition reduction and perceptual discomfort than MC-BFR, while MC-BFR demonstrates similar performances and comfort to N-BFR in later sets. Findings suggest cuff design plays a role in acute BFR responses.","PeriodicalId":20083,"journal":{"name":"Physiological Reports","volume":"13 7","pages":"e70303"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11973931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuroprotective effect of cedrol in a male rat model of Parkinson's disease.

IF 2.2

Physiological Reports Pub Date : 2025-04-01 DOI: 10.14814/phy2.70309

Fatemeh Forouzanfar, Mahmoud Hosseini, Amir Mahmoud Ahmadzadeh, Ali Mohammad Pourbagher-Shahri

{"title":"Neuroprotective effect of cedrol in a male rat model of Parkinson's disease.","authors":"Fatemeh Forouzanfar, Mahmoud Hosseini, Amir Mahmoud Ahmadzadeh, Ali Mohammad Pourbagher-Shahri","doi":"10.14814/phy2.70309","DOIUrl":"10.14814/phy2.70309","url":null,"abstract":"Cedrol is a natural sesquiterpene subgroup of terpenes with antioxidant and anti-inflammatory properties. This study evaluated the effect of cedrol on the 6-hydroxydopamine (6-OHDA) rat model of Parkinson's disease (PD). Unilateral injection of 6-OHDA was performed to induce the PD model. Cedrol at 10 mg/kg and 20 mg/kg was administrated. The rotarod test, apomorphine-induced rotational test, and open field tests assessed motor function, while the passive avoidance test was used to evaluate cognitive function. Furthermore, striatal levels of malondialdehyde (MDA) and total thiol, and SOD (superoxide dismutase) activity were measured. The induction of lesion led to a significantly higher number of rotations in the apomorphine-induced rotational test, lower maintenance in the rotarod test, as well as a shorter delay for entering into and a longer duration of time spent in the dark chamber in the passive avoidance test, versus the control group. It also enhanced the striatal levels of MDA and diminished the striatal SOD activity and level of total thiol. Administration of cedrol significantly improved behavioral tests and biochemical assays. Cedrol could benefit cognitive and motor functions in a rat model of PD. Its antioxidant properties might mediate these effects.","PeriodicalId":20083,"journal":{"name":"Physiological Reports","volume":"13 7","pages":"e70309"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11973932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microscopic messengers: Extracellular vesicles shaping gastrointestinal health and disease.

IF 2.2

Physiological Reports Pub Date : 2025-04-01 DOI: 10.14814/phy2.70292

Zhantao Yu, Kevin A Swift, Madeline A Hedges, Arianne L Theiss, Sarah F Andres

引用次数: 0

Plasma proteomic profiles correlate with organ dysfunction in COVID-19 ARDS.

IF 2.2

Physiological Reports Pub Date : 2025-04-01 DOI: 10.14814/phy2.70300

Moemen Eltobgy, Brett Klamer, Daniela Farkas, James D Londino, Joshua A Englert, Jeffrey C Horowitz, Rama K Mallampalli, Guy Brock, Joseph S Bednash

{"title":"Plasma proteomic profiles correlate with organ dysfunction in COVID-19 ARDS.","authors":"Moemen Eltobgy, Brett Klamer, Daniela Farkas, James D Londino, Joshua A Englert, Jeffrey C Horowitz, Rama K Mallampalli, Guy Brock, Joseph S Bednash","doi":"10.14814/phy2.70300","DOIUrl":"10.14814/phy2.70300","url":null,"abstract":"Severe COVID-19 is often complicated by hypoxemic respiratory failure and acute respiratory distress syndrome (ARDS). Mechanisms governing lung injury and repair in ARDS remain poorly understood. We hypothesized that plasma proteomics may uncover protein biomarkers correlated with COVID-19 ARDS severity. We analyzed the plasma proteome from 32 patients with ARDS and COVID-19 using an aptamer-based platform of 7289 proteins, and correlated protein measurements with sequential organ failure assessment (SOFA) scores at days 1 and 7 of ICU admission. We identified 184 differentially abundant proteins correlated with SOFA at day 1 and 46 proteins at day 7. In a longitudinal analysis, we correlated dynamic changes in protein abundance and SOFA between days 1 and 7 and identified 40 significant proteins. Pathway analysis of significant proteins identified increased ephrin signaling and acute phase response signaling correlated with increased SOFA scores between days 1 and 7, while pathways related to pulmonary fibrosis signaling and wound healing had a negative correlation. These findings suggest that persistent inflammation may drive disease severity, while repair processes correlate with improvements in organ dysfunction. This approach is generalizable to future ARDS cohorts for identification of biomarkers and disease mechanisms as we strive towards targeted therapies in ARDS.","PeriodicalId":20083,"journal":{"name":"Physiological Reports","volume":"13 7","pages":"e70300"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11962209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0