Physiology international最新文献_第10页

The "GG" genotype of rs26802 variant in the ghrelin gene is a potential protective factor against nonalcoholic fatty liver disease. ghrelin基因rs26802变异的“GG”基因型是预防非酒精性脂肪肝的潜在保护因素。

IF 1.4 4区医学

Physiology international Pub Date : 2021-09-16 DOI: 10.1556/2060.2021.00183

Gholamreza Rezamand, Touraj Mahmoudi, Seidamir Pasha Tabaeian, Hamid Farahani, Fatemeh Shahinmehr, Hossein Nobakht, Reza Dabiri, Asadollah Asadi, Fariborz Mansour-Ghanaei, Mohammad Reza Zali

{"title":"The \"GG\" genotype of rs26802 variant in the ghrelin gene is a potential protective factor against nonalcoholic fatty liver disease.","authors":"Gholamreza Rezamand, Touraj Mahmoudi, Seidamir Pasha Tabaeian, Hamid Farahani, Fatemeh Shahinmehr, Hossein Nobakht, Reza Dabiri, Asadollah Asadi, Fariborz Mansour-Ghanaei, Mohammad Reza Zali","doi":"10.1556/2060.2021.00183","DOIUrl":"https://doi.org/10.1556/2060.2021.00183","url":null,"abstract":"Background: Nonalcoholic fatty liver disease (NAFLD) is an emerging global chronic liver disease worldwide. Considering the powerful association between NAFLD, insulin resistance (IR) and obesity, as well as the key role of ghrelin in these metabolic disorders, we hypothesized that some single nucleotide polymorphisms (SNPs) of the ghrelin (GHRL) and ghrelin receptor (GHSR) genes might be associated with NAFLD.Methods: We conducted a case-control retrospective study of 150 cases with biopsy-proven NAFLD and 155 controls. The diagnosis of NAFLD was established before the start of the genotyping process. All the 305 subjects were genotyped for GHRL SNP rs26802 or -501T>G and GHSR SNP rs572169 or Arg159Arg using the PCR-RFLP method.Results: The GHRL rs26802 \"GG\" genotype compared with the \"TT\" genotype and \"TT+TG\" genotype appears to be a marker of decreased NAFLD susceptibility even after adjustment for confounding factors (P = 0.006; OR = 0.14, 95% CI = 0.03-0.56 and P = 0.003; OR = 0.16, 95% CI = 0.05-0.53, respectively). However, we observed no significant difference in genotype or allele frequencies between the cases and controls for GHSR SNP rs572169.Conclusions: These findings proposed, for the first time, that the GHRL rs26802 \"GG\" genotype has a protective effect against NAFLD. Nonetheless, this observation warrants further investigations in other populations.","PeriodicalId":20058,"journal":{"name":"Physiology international","volume":" ","pages":"342-352"},"PeriodicalIF":1.4,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39422290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The influence of external load variables on creatine kinase change during preseason training period. 季前训练期外负荷变量对肌酸激酶变化的影响。

IF 1.4 4区医学

Physiology international Pub Date : 2021-09-16 DOI: 10.1556/2060.2021.30019

Dániel Csala, Bence Márk Kovács, Péter Bali, Gábor Reha, Gergely Pánics

{"title":"The influence of external load variables on creatine kinase change during preseason training period.","authors":"Dániel Csala, Bence Márk Kovács, Péter Bali, Gábor Reha, Gergely Pánics","doi":"10.1556/2060.2021.30019","DOIUrl":"https://doi.org/10.1556/2060.2021.30019","url":null,"abstract":"Objective: The aim of the present study was to analyse the relationships between creatine kinase (CK) concentration, an indirect marker of muscle damage, and global positioning system (GPS)-derived metrics of a continuous two-week-long preseason training period in elite football.Design: Twenty-one elite male professional soccer players were assessed during a 14-day preseason preparatory period. CK concentrations were determined each morning, and a GPS system was used to quantify the external load. A generalized estimating equation (GEE) model was established to determine the extent to which the external load parameter explained post-training CK levels.Results: The GEE model found that higher numbers of decelerations (χ 2 = 7.83, P = 0.005) were most strongly associated with the post-training CK level. Decelerations and accelerations accounted for 62% and 11% of the post-training CK level, respectively, and considerable interindividual variability existed in the data.Conclusion: The use of GPS to predict muscle damage could be of use to coaches and practitioners in prescribing recovery practices. Based on GPS data, more individualized strategies could be devised and could potentially result in better subsequent performance.","PeriodicalId":20058,"journal":{"name":"Physiology international","volume":"108 3","pages":"371-382"},"PeriodicalIF":1.4,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9473830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Perturbation-based balance assessment: Examining reactive balance control in older adults with mild cognitive impairments. 基于微扰的平衡评估:检查轻度认知障碍老年人的反应性平衡控制。

IF 1.4 4区医学

Physiology international Pub Date : 2021-09-16 DOI: 10.1556/2060.2021.00181

Lakshmi N Kannan, Tanvi S Bhatt

{"title":"Perturbation-based balance assessment: Examining reactive balance control in older adults with mild cognitive impairments.","authors":"Lakshmi N Kannan, Tanvi S Bhatt","doi":"10.1556/2060.2021.00181","DOIUrl":"https://doi.org/10.1556/2060.2021.00181","url":null,"abstract":"Background: Older adults with mild cognitive impairment (OAwMCI) present subtle balance and gait deficits along with subjective memory decline. Although these presentations might not affect activities of daily living (ADLs), they attribute to a two-folded increase in falls. While changes occurring in volitional balance control during ADLs have been extensively examined among OAwMCI, reactive balance control, required to recover from external perturbations, has received little attention. Therefore, this study examined reactive balance control in OAwMCI compared to their healthy counterparts.Methods: Fifteen older adults with mild cognitive impairment (OAwMCI), fifteen cognitively intact older adults (CIOA) (>55 years), and fifteen young adults (18-30 years) were exposed to stance perturbations at three different intensities. Behavioral outcomes postural COM state stability, step length, step initiation, and step execution were computed.Results: Postural COM state stability was the lowest in OAwMCI compared to CIOA and young adults, and it deteriorated at higher perturbation intensities (P < 0.001). Step length was the lowest among OAwMCI and was significantly different from young adults (P < 0.001) but not from CIOA. Unlike OAwMCI, CIOA and young adults increased their step length at higher perturbation intensities (P < 0.001). OAwMCI showed longer recovery step initiation times and shorter execution times compared to CIOA and young adults at higher perturbation intensities (P < 0.001).Conclusion: OAwMCI exhibit exacerbated reactive instability and are unable to modulate their responses as the threat to balance control altered. Thus, they are at a significantly higher risk of falls than their healthy counterparts.","PeriodicalId":20058,"journal":{"name":"Physiology international","volume":" ","pages":"353-370"},"PeriodicalIF":1.4,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39422289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Ferulic acid attenuates osteoporosis induced by glucocorticoid through regulating the GSK-3β/Lrp-5/ERK signalling pathways. 阿魏酸通过调节GSK-3β/Lrp-5/ERK信号通路减轻糖皮质激素所致骨质疏松症。

IF 1.4 4区医学

Physiology international Pub Date : 2021-09-15 DOI: 10.1556/2060.2021.00180

Wei Zhou, Bo Chen, Jingbo Shang, Renbo Li

{"title":"Ferulic acid attenuates osteoporosis induced by glucocorticoid through regulating the GSK-3β/Lrp-5/ERK signalling pathways.","authors":"Wei Zhou, Bo Chen, Jingbo Shang, Renbo Li","doi":"10.1556/2060.2021.00180","DOIUrl":"https://doi.org/10.1556/2060.2021.00180","url":null,"abstract":"Objective: To evaluate in-vivo and in-vitro effects of ferulic acid (FA) on glucocorticoid-induced osteoarthritis (GIO) to establish its possible underlying mechanisms.Methods: The effects of FA on cell proliferation, cell viability (MTT assay), ALP activity, and mineralization assay, and oxidative stress markers (ROS, SOD, GSH LDH and MDA levels) were investigated by MC3T3-E1 cell line. Wistar rats received standard saline (control group) or dexamethasone (GC, 2 mg-1 kg) or DEX+FA (50 and 100 mg-1 kg) orally for 8 weeks. Bone density, micro-architecture, bio-mechanics, bone turnover markers and histo-morphology were determined. The expression of OPG, RANKL, osteogenic markers, and other signalling proteins was assessed employing quantitative RT-PCR and Western blotting.Results: The findings indicated the elevation of ALP mRNA expressions, osteogenic markers (Runx-2, OSX, Col-I, and OSN), and the β-Catenin, Lrp-5 and GSK-3β protein expressions. FA showed the potential to increase MC3T3-E1 cell differentiation, proliferation, and mineralization. FA increased oxidative stress markers (SOD, MDA, and GSH) while decreasing ROS levels and lactate dehydrogenase release in GIO rats. The OPG/RANKL mRNA expression ratio was increased by FA, followed by improved GSK-3β and ERK phosphorylation with enhanced mRNA expressions of Lrp-5 and β-catenin.Conclusion: These findings showed that FA improved osteoblasts proliferation with oxidative stress suppression by controlling the Lrp-5/GSK-3β/ERK pathway in GIO, demonstrating the potential pathways involved in the mechanism of actions of FA in GIO therapy.","PeriodicalId":20058,"journal":{"name":"Physiology international","volume":" ","pages":"317-341"},"PeriodicalIF":1.4,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39422291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Aerobic interval training improves irisin and chemerin levels of both liver and visceral adipose tissues and circulating asprosin in rats with metabolic syndrome. 有氧间歇训练提高代谢综合征大鼠肝脏和内脏脂肪组织的鸢尾素和趋化素水平以及循环阿斯丁蛋白酶水平。

IF 1.4 4区医学

Physiology international Pub Date : 2021-09-15 DOI: 10.1556/2060.2021.00182

Fereshteh Ahmadabadi, Hossein Nakhaei, Mehdi Mogharnasi, Chun-Jung Huang

{"title":"Aerobic interval training improves irisin and chemerin levels of both liver and visceral adipose tissues and circulating asprosin in rats with metabolic syndrome.","authors":"Fereshteh Ahmadabadi, Hossein Nakhaei, Mehdi Mogharnasi, Chun-Jung Huang","doi":"10.1556/2060.2021.00182","DOIUrl":"https://doi.org/10.1556/2060.2021.00182","url":null,"abstract":"The perturbation of adipokinetic hormones, such as irisin, chemerin, and asprosin has been reported to participate in pathological conditions (e.g., insulin resistance) and chronic inflammation. However, exercise training has been long established as an effective intervention for prevention and treatment of these chronic and metabolic diseases. This study was to examine the effects of aerobic continuous training (ACT) and aerobic interval training (AIT) on irisin and chemerin levels of liver tissue (LT) and visceral adipose tissue (VAT), circulating asprosin, and their relationships with cardiometabolic risk factors in rats with metabolic syndrome (MetS). Thirty-two male Wistar rats were randomly divided into four equal groups: normal control (N-Ctr), control (Ctr-MetS), ACT, and AIT. After familiarization, rats with exercise intervention performed either ACT or AIT five times a week over eight weeks. The level of irisin in both ACT and AIT groups was higher than the Ctr-MetS group in LT and VAT, with a greater improvement of LT level observed in AIT vs. ACT groups. Furthermore, the level of chemerin in LT and VAT was lower in both ACT and AIT groups than the Ctr-MetS group, whereas only AIT group exhibited a reduction of serum asprosin when compared to ACT and Ctr-MetS, along with the improvements of cardiometabolic markers, such as HOMA-IR and lipid profile. These findings may support the efficiency and effectiveness of AIT intervention in the modulation of these novel metabolic hormones and cardiometabolic risk factors for reduced risk of metabolic syndrome.","PeriodicalId":20058,"journal":{"name":"Physiology international","volume":" ","pages":"383-397"},"PeriodicalIF":1.4,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39422292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The effect of strength-endurance training on serum and urine metabolic profiles of female adolescent volleyball athletes. 力量耐力训练对青少年女排球运动员血清和尿液代谢的影响。

IF 1.4 4区医学

Physiology international Pub Date : 2021-06-25 DOI: 10.1556/2060.2021.00150

W Zhou, G Zeng, C Lyu, F Kou, S Zhang, H Wei

{"title":"The effect of strength-endurance training on serum and urine metabolic profiles of female adolescent volleyball athletes.","authors":"W Zhou, G Zeng, C Lyu, F Kou, S Zhang, H Wei","doi":"10.1556/2060.2021.00150","DOIUrl":"https://doi.org/10.1556/2060.2021.00150","url":null,"abstract":"Aim: Limited investigations on metabolic responses to exercise training in female adolescent volleyball athletes exist. The aim of this study was to obtain serum and urine metabolite markers in female adolescent volleyball athletes within 2-week strength-endurance training using a metabolomics approach coupled with biochemical analysis, which would be potential biomarkers for evaluating the physiological state of athletes.Methods: Twelve female adolescent volleyball athletes were recruited for 2-week strength-endurance training. Differential serum and urine metabolic profiles between the pre- and post-training group were obtained on gas chromatography coupled to mass spectrometry (GC-MS) and data subsequently underwent orthogonal partial least-squares analysis (OPLS).Results: Strength-endurance training exerted a significant influence on the athletes' serum and urine metabolic profiles. The changed metabolites were primarily involved in energy metabolism, lipid metabolism and amino acids metabolism. Results support the hypothesis that female athletes displayed an increased propensity to oxidize lipids as the major energy source. Exposure to strength-endurance training also led to a significant increase in cortisol, but a decrease in testosterone, indicating disordered hormone adjustment. Exercise-induced oxidative stress occurred, as was evidenced by the decrease in reduced glutathione, and increases in blood malondialdehyde and oxidized glutathione. Since the muscle damage markers creatine kinase and lactate dehydrogenase did not show significant changes, the training might not cause cell membrane damage and the athletes did not cross the adaptive injury level.Conclusion: By measurement of endogenous metabolites, the metabolomics study has the potential to reveal the global physiological changes in response to exercise training.","PeriodicalId":20058,"journal":{"name":"Physiology international","volume":"108 2","pages":"285-302"},"PeriodicalIF":1.4,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39136208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Longer Achilles tendon moment arm results in better running economy. 更长的跟腱力臂导致更好的跑步经济性。

IF 1.4 4区医学

Physiology international Pub Date : 2021-01-12 DOI: 10.1556/2060.2020.10000

B Kovács, I Kóbor, Ö Sebestyén, J Tihanyi

{"title":"Longer Achilles tendon moment arm results in better running economy.","authors":"B Kovács, I Kóbor, Ö Sebestyén, J Tihanyi","doi":"10.1556/2060.2020.10000","DOIUrl":"https://doi.org/10.1556/2060.2020.10000","url":null,"abstract":"Based on the current literature, the link between Achilles tendon moment arm length and running economy is not well understood. Therefore, the aim of this study was to further investigate the connection between Achilles tendon moment arm and running economy and the influence of Achilles tendon moment arm on the function of the plantarflexor muscle-tendon unit during running.Ten male competitive marathon runners volunteered for this study. The participants ran on a treadmill at two running speeds: 3 and 3.5 m s-1. During running the oxygen consumption, lower leg kinematics, electrical activity of plantar flexor muscles, and fascicle behavior of the lateral gastrocnemius were measured simultaneously. On the second occasion, an MRI scan of the right leg was taken and used to estimate the Achilles tendon moment arm length.There was a negative correlation between running economy and the body height normalized moment arm length at both selected speeds (r = -0.68, P = 0.014 and r = -0.70, P = 0.01). In addition, Achilles tendon moment arm length correlated with the amplitude of the ankle flexion at both speeds (r = -0.59, P = 0.03 and r = -0.60, P = 0.03) and with the electrical activity of the medial gastrocnemius muscle at 3 m s-1 speed (r = -0.62, P = 0.02). Our finding supports the concept that a longer moment arm could be beneficial for distance runners.","PeriodicalId":20058,"journal":{"name":"Physiology international","volume":"107 4","pages":"527-541"},"PeriodicalIF":1.4,"publicationDate":"2021-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39127528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Evaluation of oxidative/nitrative stress and uterine artery pulsatility index in early pregnancy. 妊娠早期子宫动脉搏动指数及氧化/硝化应激的评价。

IF 1.4 4区医学

Physiology international Pub Date : 2021-01-06 DOI: 10.1556/2060.2020.00041

D Gerszi, Á Penyige, Z Mezei, B Sárai-Szabó, R Benkő, B Bányai, C Demendi, E Ujvári, S Várbíró, E M Horváth

{"title":"Evaluation of oxidative/nitrative stress and uterine artery pulsatility index in early pregnancy.","authors":"D Gerszi, Á Penyige, Z Mezei, B Sárai-Szabó, R Benkő, B Bányai, C Demendi, E Ujvári, S Várbíró, E M Horváth","doi":"10.1556/2060.2020.00041","DOIUrl":"https://doi.org/10.1556/2060.2020.00041","url":null,"abstract":"Introduction: Increased oxidative/nitrative stress is characteristic not only in pathologic, but also in healthy pregnancy. High uterine artery pulsatility index (UtAPI) at the end of the first trimester is associated with altered placentation and elevated risk for adverse pregnancy outcomes. We aimed to examine the relationship of systemic oxidative/nitrative stress and uterine artery pulsatility index in the first trimester and their correlation to pregnancy outcomes.Material and methods: Healthy pregnant women were recruited at 12-13th gestational week ultrasound examination; UtAPI was determined by color Doppler ultrasound. Patients were divided into high (UtAPI ≥ 2.3) (n = 30) and low (n = 31) resistance groups, and pregnancies were followed until labor. Systemic oxidative/nitrative stress was estimated by measuring total peroxide level, total antioxidant capacity and nitrotyrosine level.Results: Plasma total peroxide level was significantly lower (2,510 ± 39 µM vs. 2,285 ± 59 µM), total antioxidant capacity was higher (781 ± 16 mM CRE vs. 822 ± 13 mM CRE) in the high UtAPI group, which were accompanied by lower birth weight (3,317 ± 64 vs. 3,517 ± 77 g, P < 0.05). Plasma total peroxide level showed a negative correlation (by Pearson) to UtAPI (P < 0.01) and positive correlation to birth weight (P < 0.05).Conclusions: According to our results, lower systemic oxidative stress showed correlation with high UtAPI measured between the 12-13th weeks of gestation. We also found significant differences in the birth weight of healthy newborns; therefore it is worth examining this relationship in pathological pregnancies.","PeriodicalId":20058,"journal":{"name":"Physiology international","volume":"107 4","pages":"479-490"},"PeriodicalIF":1.4,"publicationDate":"2021-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39127076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Plasma irisin and its associations with oxidative stress in athletes suffering from overtraining syndrome. 血浆鸢尾素及其与过度训练综合征运动员氧化应激的关系。

IF 1.4 4区医学

Physiology international Pub Date : 2020-12-31 DOI: 10.1556/2060.2020.00037

R Joro, A Korkmaz, T A Lakka, A L T Uusitalo, M Atalay

{"title":"Plasma irisin and its associations with oxidative stress in athletes suffering from overtraining syndrome.","authors":"R Joro, A Korkmaz, T A Lakka, A L T Uusitalo, M Atalay","doi":"10.1556/2060.2020.00037","DOIUrl":"https://doi.org/10.1556/2060.2020.00037","url":null,"abstract":"Irisin is a novel exercise-induced myokine that may be involved in regulating energy metabolism. We determined whether overtraining syndrome (OTS) and its biochemical markers are associated with plasma irisin levels in athletes. Seven severely overtrained athletes (OA) and 10 healthy control athletes (CA) were recruited and examined at the time of diagnosis (baseline) and after 6- and 12-months follow-up. Training volume and intensity were initially restricted but progressively increased in OA as OTS symptoms alleviated; CA continued their normal training routine. A maximal cycle ergometer test was performed with irisin analyzed before and after the test. Before the exercise test, irisin levels tended to be lower in OA than in CA at baseline (154.5 ± 28.5 vs. 171.7 ± 58.7 ng/mL). In both groups, at rest irisin levels changed only marginally during follow-up and were not affected by maximal exercise, nor were they associated with physical performance or body fat percentage. Irisin concentration at rest correlated positively with an oxidative stress marker, malondialdehyde (MDA) and negatively with an antioxidant protection marker, oxygen radical absorbance capacity (ORAC) in response to the exercise test in OA at baseline. Our findings help to clarify the possible contribution of irisin and its association with oxidative stress in the pathophysiology of OTS.","PeriodicalId":20058,"journal":{"name":"Physiology international","volume":"107 4","pages":"513-526"},"PeriodicalIF":1.4,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39113167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Non-linear heart rate dynamics during and after three controlled exercise intensities in healthy men. 健康男性在三种控制运动强度期间和之后的非线性心率动态。

IF 1.4 4区医学

Physiology international Pub Date : 2020-12-24 DOI: 10.1556/2060.2020.00039

J Naranjo-Orellana, C Nieto-Jiménez, J F Ruso-Álvarez

{"title":"Non-linear heart rate dynamics during and after three controlled exercise intensities in healthy men.","authors":"J Naranjo-Orellana, C Nieto-Jiménez, J F Ruso-Álvarez","doi":"10.1556/2060.2020.00039","DOIUrl":"https://doi.org/10.1556/2060.2020.00039","url":null,"abstract":"We aimed to analyse the complexity and fractal nature of heartbeat during constant exercise, at three different intensities, and recovery.Fourteen healthy men underwent 4 separate sessions. The first session was an incremental treadmill test to determine ventilatory thresholds (VT1 and VT2) and maximal aerobic speed (MAS). Each subject ran at VT1 and VT2 speeds and MAS (second, third and fourth day). The duration of VT1 and VT2 loads were selected in such a way that the product intensity-duration (training load) was the same. Sample Entropy (SampEn) and slope of Detrended Fluctuation Analysis (DFA α1) were measured during the whole session.DFA α1 declines with exercise, being less in the VT1 trial than in the other two.SampEn shows no significant change during exercise. The three tests induce the same decline in SampEn, but at the highest intensity (MAS) tends to decline during the exercise itself, whereas at lower intensities (VT1, VT2) the decline is delayed (10 min of recovery). Subsequently, SampEn at VT1 gradually recovers, whereas at VT2 and MAS it remains stable during recovery.In conclusion, exercise produces a loss of heartbeat complexity, but not fractal nature, during recovery and it depends on intensity.","PeriodicalId":20058,"journal":{"name":"Physiology international","volume":"107 4","pages":"501-512"},"PeriodicalIF":1.4,"publicationDate":"2020-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38760188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8