Phosphorus, Sulfur, and Silicon and the Related Elements最新文献

{"title":"Synthesis, characterization and anticancer screening of novel phenylbenzylidene thiosemicarbazone derivatives","authors":"S. Anisree ,&nbsp;P. Shanmugavelan ,&nbsp;P. Vijayalakshmi ,&nbsp;Ram Kishore ,&nbsp;Nitin Srivastava","doi":"10.1080/10426507.2024.2330935","DOIUrl":"10.1080/10426507.2024.2330935","url":null,"abstract":"<div><p>Ten derivatives of phenylbenzylidene thiosemicarbazones (<strong>1</strong>–<strong>10</strong>) were synthesized by multicomponent reaction between hydrazine hydrate, isothiocyanate and substituted aldehydes in the presence of the phase transfer reagent Triton-B and subsequently heating the mixture. The synthesized compounds <strong>1</strong>, <strong>2</strong>, <strong>5</strong>, <strong>8</strong> demonstrated to act as highly potent anticancer agents. They showed anticancer activity by mobilizing cellular ⁵⁹Fe, inhibiting cellular uptake of ⁵⁹Fe from ⁵⁹Fe₂-Tf, and mediating the ascorbate oxidation. Further, the structure activity relationship revealed that the donor atom and its stabilization resulted in better anticancer activity. The softness of the chelating donor atoms N and S yielded redox active iron complexes, which easily mediated ascorbate oxidation. This study identified the selective and potential chelators, which may act as anticancer agents and require further <em>in vivo</em> screening in future.</p></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"199 4","pages":"Pages 267-276"},"PeriodicalIF":1.3,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140299826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of new 4-aminobenzoic acid (PABA) hydrazide-hydrazone/sulfonate hybrids and antimicrobial evaluation with ascorbic acid/salicylic acid/N-acetyl cysteine combinations","authors":"M. İhsan Han ,&nbsp;Ufuk İnce ,&nbsp;G. Pelin Coşkun ,&nbsp;Kaan Birgül ,&nbsp;Şengül Dilem Doğan ,&nbsp;Amir Ashoorzadeh ,&nbsp;Ş. Güniz Küçükgüzel","doi":"10.1080/10426507.2024.2341145","DOIUrl":"10.1080/10426507.2024.2341145","url":null,"abstract":"<div><p>One of the most serious threats to human health is the increasing prevalence of drug-resistant pathogens. The development of new antibiotics capable of combating drug resistance is critical. In various bacteria and plant species, 4-aminobenzoic acid (PABA) is produced and used as a substrate for folate generation. In this study, a new series of PABA analogs were synthesized and evaluated for their antimicrobial activity. Thirteen novel compounds were prepared by linking PABA hydrazide to sulfonate esters <em>via</em> a hydrazone bridge (<strong>4a</strong>–<strong>m</strong>). The structures of these compounds were characterized by ¹H and ¹³C NMR and FT-IR spectroscopy as well as by LC-MS. Following structural characterization, all compounds were tested for their antimicrobial activity against <em>Staphylococcus aureus</em> (ATCC 29213), <em>Enterococcus faecium</em> (ATCC 19434), <em>Escherichia coli</em> (ATCC 25922), <em>Pseudomonas aeruginosa</em> (ATCC 27853), and <em>Candida albicans</em> (ATCC 10231) strains. Four compounds were found to have moderate antimicrobial activity against the <em>P. aeruginosa</em> strain. These compounds, including <strong>4e, 4f, 4g</strong>, and <strong>4m</strong>, containing a hydrazide-hydrazone sulfonate functionality, showed the best MIC value of 64 μg/mL. In addition, synergistic effects of ascorbic acid, salicylic acid, and <em>N</em>-acetyl cysteine (NAC) with synthesized compounds were also investigated. It was observed that the combination of compounds <strong>4f</strong> and <strong>4g</strong> with NAC showed antipseudomonal activity with MIC values of 32 μg/mL and 16 μg/mL, respectively, against the <em>P. aeuriginosa</em> strain. The antimicrobial activity of <strong>4f</strong> and <strong>4g</strong> was enhanced by two folds in combination with NAC. Our findings in this study can be crucial for the development of new potent antimicrobial agents.</p></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"199 4","pages":"Pages 316-323"},"PeriodicalIF":1.3,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140666913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A facile ultrasonic synthesis approach to 3-H-quinazolinethione derivatives and their urease inhibition studies","authors":"Nedime Çalışkan ,&nbsp;Gülay Akyüz ,&nbsp;Emre Menteşe","doi":"10.1080/10426507.2024.2333471","DOIUrl":"10.1080/10426507.2024.2333471","url":null,"abstract":"<div><p>In this study, a new series of 3<em>H-</em>quinazoline-4-thione derivatives were synthesized under ultrasonic irradiation conditions with high yield in a short time. The new compounds were characterized by FT-IR,¹H, and ¹³C NMR spectral data. The antiurease activities of all new compounds were tested according to the method by Weatherburn. The inhibition results with the 3<em>H-</em>quinazoline-4-thione ring compounds were compared with those of some previously synthesized 3<em>H-</em>quinazolin-4-ones. More effective results were found for most quinazolinethione compounds. All new synthesized compounds have effective urease inhibition activity. Especially, the compound 2-(4-nitrobenzyl)quinazoline-4(3<em>H</em>)-thione (<strong>2i</strong>) has the best inhibition results with IC₅₀ = 1.6 ± 0.049 μg/mL.</p></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"199 4","pages":"Pages 293-298"},"PeriodicalIF":1.3,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140370942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green conversion of CO2 by N-heterocyclic carbene-CO2 adducts grafted hierarchical porous silica microspheres","authors":"Xueting Liu ,&nbsp;Kuayue Li ,&nbsp;Wenkui Liu ,&nbsp;Peng Cui ,&nbsp;Fengyu Wei","doi":"10.1080/10426507.2024.2332891","DOIUrl":"10.1080/10426507.2024.2332891","url":null,"abstract":"<div><p>The multiphase catalysts DMSNs-Cb-X containing NHC-CO₂ adducts were synthesized by soft template method that is, first preparing dendritic multi-model pore silica nanoparticles (DMSNs) with central-radial structure, and then grafting imidazoline functional groups, and finally allowing to react with dimethyl carbonate to graft NHC-CO₂ adducts. The investigations had the scope to improve the performance and to elucidate the effect of NHC-CO₂ adducts on the CO₂ cycloaddition reaction. The optimum catalyst DMSNs-Cb-1 and the optimum reaction conditions (200 mg, 100 °C, 10 h) were obtained <em>via</em> thermogravimetric analysis. CO₂ cycloaddition reaction with epoxide DMSNs-Cb-1 can convert CO₂ and epoxide to cyclic carbonate at ambient pressure without solvent and co-catalysts (1 bar, 100 °C). The reaction proceeds with high yield and high conversion frequency (TOF = 27.4 h⁻¹). The prepared catalyst is easily recovered and still has high activity after five cycles of experiments. The excellent catalytic performance of the obtained catalyst can be attributed to the synergy of hierarchical porous structure and NHC-CO₂ adducts acting as CO₂ adsorption sites as well as zwitterionic catalytic sites. This work demonstrates an efficient strategy for green conversion of CO₂ into cyclic carbonates.</p></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"199 4","pages":"Pages 283-292"},"PeriodicalIF":1.3,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140372102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the effect of halide counterions on the potential corrosion inhibitor in imidazolium-based ionic liquids","authors":"Abdelmajeed Adam Lagum ,&nbsp;Saroj Sharma ,&nbsp;Anupam Yadav ,&nbsp;Parminder Singh ,&nbsp;Shakir Mahmood Saeed ,&nbsp;Russul R. Abbass ,&nbsp;Ali H. Hameed ,&nbsp;Mustafa M. Kadhim","doi":"10.1080/10426507.2024.2340006","DOIUrl":"10.1080/10426507.2024.2340006","url":null,"abstract":"<div><p>Imidazolium (IMZ)-based ionic liquids (ILs) with various counter ions were investigated as potential corrosion inhibitors. Furthermore, parameters such as bond lengths, bond angles, and dihedral bonds were investigated to demonstrate the adsorption sites of molecules. Moreover, in order to compare the efficiency of the inhibitors, other parameters such as energy gap, hardness, the LUMO, and the HOMO were investigated. The HOMO and LUMO values increased from −4.370 and −0.106 eV to −4.959 and −0.156 eV, respectively, by changing F⁻ to I⁻. Moreover, the softness of the IMZ base changed from 0.469 to 0.417 eV by increasing the radius of the halide ion. The trend of the band gap value in going from F⁻ to I⁻ changes from 4.264 to 4.797 eV. The total electron density was computed to show the adsorption sites based on the electron density. According to the molecular reactivity results, the inhibitory efficiency of the inhibitors was in the following order: BMI-F &gt; BMI-Cl &gt; BMI-Br &gt; BMI-I. Investigating the IMZ-based ILs with various counterions to evaluate the inhibition profile of molecules provides useful insights into computational protocols for the study of corrosion inhibitors.</p></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"199 4","pages":"Pages 308-315"},"PeriodicalIF":1.3,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140972124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"1-Phosphanorbornane aldehyde as precursor for enantiopure P,N,N ligands","authors":"Kyzgaldak Ramazanova ,&nbsp;Nadja Kretzschmar ,&nbsp;Peter Lönnecke ,&nbsp;Evamarie Hey-Hawkins","doi":"10.1080/10426507.2024.2338393","DOIUrl":"10.1080/10426507.2024.2338393","url":null,"abstract":"<div><p>Sulfur-protected enantiomerically pure 1-phosphanorbornane aldehyde <strong>5</strong> is obtained in good yield <em>via</em> Swern oxidation of the previously reported 1-phosphanorbornane alcohol. The aldehyde is further used to prepare a novel sulfur-protected 1-phosphanorbornane enamine.</p></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"199 4","pages":"Pages 303-307"},"PeriodicalIF":1.3,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140615288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The syntheses of 2-hydroxybenzothiazole substituted cyclotriphosphazenes: Spectroscopic characterizations","authors":"Saliha Begeç","doi":"10.1080/10426507.2024.2318600","DOIUrl":"10.1080/10426507.2024.2318600","url":null,"abstract":"<div><p>The nucleophilic substitution reactions of mono- and bis-spiro-2,2’-dioxybiphenyl cyclotriphosphazenes (<strong>1a</strong> and <strong>1b</strong>) with 2-hydroxybenzothiazole (<strong>2</strong>) were performed in the presence of metallic sodium in THF. Two novel 2-oxybenzothiazole-substituted spiro-2,2′-dioxybiphenyl cyclotriphosphazene derivatives (<strong>3a</strong> and <strong>3b</strong>) were obtained from these reactions. Both compounds (<strong>3a, 3b</strong>) have been characterized by elemental analysis as well as by ¹H, ¹³C and ³¹P NMR spectroscopy. Compounds <strong>3a</strong> and <strong>3b</strong> are reported for the first time in this study.</p></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"199 4","pages":"Pages 277-282"},"PeriodicalIF":1.3,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141110018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promising way for enhancing light absorption in silicon via silver nanoparticles: experimental and numerical study","authors":"Meriem Zineb Belmehdi ,&nbsp;Fatiha Bechiri ,&nbsp;Mohamed Amine Benali ,&nbsp;Mokhtar Zerdali","doi":"10.1080/10426507.2024.2318593","DOIUrl":"10.1080/10426507.2024.2318593","url":null,"abstract":"<div><p>Silver nanoparticles (Ag-Nps) were grown on the surface of a p-type crystalline silicon (C-Si) substrate using electroless metal deposition. It was found that the Ag-Nps distribution on C-Si was controlled by the silver nitrate (AgNO₃) concentrations. Atomic force microscopy observations revealed the formation of a continuous layer at high concentration. In contrast, a distribution of Ag-Nps with a spherical shape was obtained at lower concentration. The samples were also examined by optical microscopy under dark field illumination. The light reflected from Ag-Nps was obtained with different colors. This difference indicates a slight change in particle size. It is demonstrated that a silicon substrate with deposited Ag-Nps shows a significant decrease in reflectance and an increase of the absorption in the region from 200 to 800 nm. Moreover, the behavior of small Ag-Nps while interacting with light (absorbed or scattered light) is theoretically described using the Mie theory based on the Drude model. The introduction of silver nanoparticles on silicon surface is used to improve the efficiency of solar cells by reducing reflection and increasing the light absorption.</p></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"199 3","pages":"Pages 227-235"},"PeriodicalIF":1.3,"publicationDate":"2024-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139947199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design, synthesis and antibacterial evaluation of N-substituted indole derivatives containing 1,3,4-thiadiazole and amide moieties","authors":"Chenghao Tang ,&nbsp;Chou Si ,&nbsp;Yidan Zhang ,&nbsp;Shengzhou Yang ,&nbsp;Xingju Chen ,&nbsp;Pei Li ,&nbsp;Xiang Wang","doi":"10.1080/10426507.2024.2318584","DOIUrl":"10.1080/10426507.2024.2318584","url":null,"abstract":"<div><p>A total of eighteen novel 2-(1<em>H</em>-indol-1-yl)-<em>N</em>-(5-phenyl-1,3,4-thiadiazol-2-yl) acetamide derivatives were synthesized through the condensation reaction of 2-(1<em>H</em>-indol-1-yl) acetic acid and 5-phenyl-1,3,4-thiadiazol-2-amine <em>via</em> fragment-based design strategy. The target compounds were subjected to screening for antibacterial activity against <em>Xanthomonas oryzae</em> pv. <em>Oryzae</em>, <em>Xanthomonas axonopodis</em> pv. <em>Citri</em> and <em>Pseudomonas syringae</em> pv. <em>Actinidiae</em>. The preliminary antibacterial evaluation of the target compounds showed that some target compounds possessed moderate to good activities against <em>Xoo</em> and <em>Xac</em>. Among them, compound <strong>3p</strong> exhibited best inhibition effects against <em>Xoo</em> (77.85% and 62.15%, respectively) and <em>Xac</em> (52.51% and 36.48%, respectively) at 100 <em>μ</em>g/mL and 50 <em>μ</em>g/mL, which were superior to Thiodiazole-copper and Bismerthiazol. To the best of our knowledge, it is the first report on the design, synthesis, and antibacterial evaluation of novel indole-derived compounds containing 1,3,4-thiadiazole and amide moieties.</p></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"199 3","pages":"Pages 193-200"},"PeriodicalIF":1.3,"publicationDate":"2024-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139947230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Removal of Ca(II) and Mg(II) ions from solutions to sulfonic cation exchanger based on plasticized polyvinylchloride","authors":"Davron Bekchanov ,&nbsp;Mukhtar Mukhamediev ,&nbsp;Murod Juraev ,&nbsp;Rasim Alosmanov","doi":"10.1080/10426507.2024.2315530","DOIUrl":"10.1080/10426507.2024.2315530","url":null,"abstract":"<div><p>The ion-exchange material was obtained by oxidation of the product of the interaction of polyvinyl chloride with an aqueous solution of calcium polysulfide. The structure of the resulting cation exchanger and metal-containing hybrid material was identified by IR spectroscopy and elemental analysis. The kinetics of absorption of metal ions in cation exchange resin was analyzed by using pseudo-first and pseudo-second order models. The rate constants in the adsorption process were calculated. According to the correlation coefficient, it was determined that the sorption process proceeds according to the laws of a pseudo-second order reaction. Based on the equilibrium sorption it was evaluated according to the isotherm models of Langmuir, Freundlich, Temkin, and Dubinin-Radushkevich (D-R). The results showed that the absorption of Ca²⁺ and Mg²⁺ ions from aqueous solutions in cation exchange resin displays the best accordance with the Langmuir monomolecular theory. In addition, the results showed that the cation exchanger (PVC-SO₃H) effectively cleans river water from Ca²⁺ and Mg²⁺ ions for industrial enterprises.</p></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"199 3","pages":"Pages 201-209"},"PeriodicalIF":1.3,"publicationDate":"2024-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139902544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}