Phosphorus, Sulfur, and Silicon and the Related Elements最新文献_第2页

Synthesis and biological evaluation of methylene spacer incorporated 4-methylsulfonyl phenyl semicarbazones as dual FAAH-MAGL inhibitors 含4-甲基磺酰基苯基氨基脲的亚甲基间隔剂的合成及生物学评价

IF 1.4 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2025-03-04 DOI: 10.1080/10426507.2025.2467438

Shivani Jaiswal , Senthil Raja Ayyannan

{"title":"Synthesis and biological evaluation of methylene spacer incorporated 4-methylsulfonyl phenyl semicarbazones as dual FAAH-MAGL inhibitors","authors":"Shivani Jaiswal , Senthil Raja Ayyannan","doi":"10.1080/10426507.2025.2467438","DOIUrl":"10.1080/10426507.2025.2467438","url":null,"abstract":"<div><div>Building upon our previous work, we investigated the impact of a methylene spacer on the dual fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) inhibition activity of 4-methylsulfonylphenyl semicarbazones by designing and synthesizing a set of extended semicarbazone analogs. The inhibition data demonstrated that several compounds had a good inhibitory activity against both FAAH and MAGL. Compound <strong>15h</strong>, [1-(4-hydroxyphenyl)ethylidene]-2-{[4-(methylsulfonyl)phenyl]amino}acetohydrazide, exhibited a well-balanced FAAH and MAGL inhibition activity with IC<sub>50</sub> values of 48 nM and 40 nM, respectively. The enzyme kinetics studies demonstrated that compound <strong>15h</strong> inhibits FAAH and MAGL reversibly with noncompetitive and mixed inhibition mode, respectively. Moreover, these experimental results were also supported by molecular modeling and simulation studies. The dual FAAH-MAGL inhibitor <strong>15h</strong>, exhibited no cytotoxicity on human neuronal SH-SY5Y cell lines and showed significant neuroprotection in LPS-induced toxicity. Further, compound <strong>15h</strong> showed potent analgesic activity and relieved oxidative stress in rats induced by chronic constriction injury (CCI) surgery. Furthermore, compound <strong>15h</strong> was non-hepatotoxic up to 2000 mg/kg (po). Overall, the present study identified compound <strong>15h</strong> as a promising dual FAAH-MAGL inhibitor and anti-nociceptive agent that merits further investigation.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 3","pages":"Pages 274-296"},"PeriodicalIF":1.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A convenient method for synthesis of Morita-Baylis-Hillman (MBH) 1,3-diene adducts and their in silico physicochemical, pharmacokinetics, and molecular docking evaluation studies Morita-Baylis-Hillman (MBH) 1,3-二烯加合物的简便合成方法及其硅理化、药代动力学和分子对接评价研究

IF 1.4 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2025-03-04 DOI: 10.1080/10426507.2025.2473917

Ferid Yaccoubi , Haitham Elleuch , Eman S. Abou-Amra , Ahmed M. Hussein

{"title":"A convenient method for synthesis of Morita-Baylis-Hillman (MBH) 1,3-diene adducts and their in silico physicochemical, pharmacokinetics, and molecular docking evaluation studies","authors":"Ferid Yaccoubi , Haitham Elleuch , Eman S. Abou-Amra , Ahmed M. Hussein","doi":"10.1080/10426507.2025.2473917","DOIUrl":"10.1080/10426507.2025.2473917","url":null,"abstract":"<div><div>A series of Morita-Baylis-Hillman (MBH) 1,3-diene adducts are obtained according to a new, simple and practical method under mild operating conditions. Indeed, the action of <em>t-</em>BuOK on the cyclic allylic phosphonates of MBH in THF at room temperature leads to the corresponding 1,3-dienes with high stereoselectivity and good yields. The two <em>Z</em> and <em>E</em> isomers are determined by examining the NMR spectra which reveal, that the <em>E</em> configuration isomer is highly predominant. Density functional theory (DFT) computational analyses of compounds <strong>3f</strong> and <strong>3 g</strong> were performed to figure out the molecular structures and topologies of the predicted more energetic compounds, using the B3LYP functional and the 6-31 G(d,p) basis set. The HOMO- LUMO, and MEP analyses were visualized with the help of the Gaussview program. Multiwfn software is used for electron localization function (ELF) and localized orbital locator (LOL). We docked the synthesized compounds <strong>3a-3g</strong> and <strong>3 m</strong> into the protein binding sites of cyclooxygenase-1 (PDB ID: 3KK6) and cyclooxygenase-2 (PDB ID: 1CX2) to examine the binding mechanism, non-bonding interactions, and binding affinity of the tested compounds, using the molecular operating environment (MOE) 2015 program. Swiss ADME web tool is used to determine the physicochemical properties of the compounds: absorption, distribution, metabolism, elimination and toxicity (ADME), and drug-likeness characteristics.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 3","pages":"Pages 297-312"},"PeriodicalIF":1.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phospha-Mannich reactions of hypophosphorous acid H3PO2 次磷酸H3PO2的磷酸-曼尼希反应

IF 1.4 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2025-03-04 DOI: 10.1080/10426507.2025.2477186

Dmitry V. Moiseev (Conceptualization Formal analysis Investigation Visualization Writing – original draft Writing – review & editing)

{"title":"Phospha-Mannich reactions of hypophosphorous acid H3PO2","authors":"Dmitry V. Moiseev (Conceptualization Formal analysis Investigation Visualization Writing – original draft Writing – review & editing)","doi":"10.1080/10426507.2025.2477186","DOIUrl":"10.1080/10426507.2025.2477186","url":null,"abstract":"<div><div>Hypophosphorous (phosphinic) acid H<sub>2</sub>P(O)OH, due to the acid-promoted equilibrium with the trivalent tautomer – phosphonous acid HP(OH)<sub>2</sub>, participates in phospha-Mannich reactions with imine/iminium species, or their donors, to give a variety of mono- and bis-(α-aminoalkyl)phosphinic compounds (PO<sub>2</sub>,N-acetals). These reactions are more complex than those involving phosphines or secondary phosphine oxides, reviewed previously, and are commonly accompanied by several side-reactions, resulted from instability of H<sub>3</sub>PO<sub>2</sub> and the presence of hypophosphite anion, a reductant. Unlike basic phosphines and neutral phosphine oxides, H<sub>3</sub>PO<sub>2</sub> and its phospha-Mannich products can mimic carboxylic acids in biological processes and chemistry, and synthesis of phosphinic analogs of natural α-amino acids, used to design phosphinic pseudopeptides, is one of the major applications of H<sub>3</sub>PO<sub>2</sub> and its synthons, such as phosphonites (RO)<sub>2</sub>PH (R = SiMe<sub>3</sub>, alkyl) and alkyl dialkoxymethylphosphinates (R’O)<sub>2</sub>CHP(O)(OR’)H. H<sub>3</sub>PO<sub>2</sub> is a unique P-nucleophile that can produce relatively stable acetals with a P–H function, widely used for further derivatization. Phospha-Mannich reactions of H<sub>3</sub>PO<sub>2</sub> also provide a variety of (α-aminoalkyl)phosphinic compounds, applied as flame-retardant or chelators of di- and tri-valent metal ions useful in metal-based (radio)pharmaceuticals for imaging and therapy.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 3","pages":"Pages 197-250"},"PeriodicalIF":1.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the degradation efficiency and possible mechanism of various chemical decontaminants on series of vesicant sulfur mustards 评价各种化学去污剂对一系列发泡剂硫芥菜的降解效率及可能机理

IF 1.4 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2025-03-04 DOI: 10.1080/10426507.2025.2464778

Mengyao Zhang , Wei You , Yulong Liu , Jinlong Cai , Bin Xu , Jia Chen , Yuxu Zhong , Jiyong Fan , Jianfeng Wu , Jianwei Xie

{"title":"Evaluation of the degradation efficiency and possible mechanism of various chemical decontaminants on series of vesicant sulfur mustards","authors":"Mengyao Zhang , Wei You , Yulong Liu , Jinlong Cai , Bin Xu , Jia Chen , Yuxu Zhong , Jiyong Fan , Jianfeng Wu , Jianwei Xie","doi":"10.1080/10426507.2025.2464778","DOIUrl":"10.1080/10426507.2025.2464778","url":null,"abstract":"<div><div>Decontamination is one of the most effective ways to reduce the hazards of different sulfur mustards. Herein, reactions of various sulfur mustards with four classic decontaminant agents were investigated and their products identified by UPLC-MS/HRMS and GC-MS. Quantitative determinations of individual products in the reaction mixture allows to evaluate the kinetic parameters of the mustard reactions. The degradation rate of 1,2-bis(2-chloroethylthio) ethane and bis(2-chloroethylthioethyl) ether is obviously faster than that of sulfur mustard (SM), but the degradation rate of bis(2-chloroethylthio) methane and bis(2-chloroethylthiomethyl) ether is slower than that of SM. Degradation occurred in a nucleophilic substitution reaction between 2,3-butanedione monoximate, sodium phenolate, and with susceptible sites in the mustards. DS2 mainly exerts its degradation function by elimination reactions. However, 2,3-monoximate degrades sulfur mustards through nucleophilic substitution and elimination reaction. Based on the results of quantumchemical calculations, we assume that the difference of the decontamination rate may be related to the electrostatic potential energy of mustards itself.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 3","pages":"Pages 251-260"},"PeriodicalIF":1.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polyfunctional dithiocarbamato-containing pyrroles: Synthesis and evaluation of antimicrobial and antioxidant activities 含多官能团二硫代氨基橡胶吡咯：抗菌和抗氧化活性的合成与评价

IF 1.4 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2025-03-04 DOI: 10.1080/10426507.2025.2475948

Alina M. Grozav , Sergiy V. Kemskyi , Mariana Z. Fedoriv , Vitaliy O. Chornous , Lesya M. Saliyeva , Nataliia Yu. Slyvka , Nina D. Yakovychuk , Valentyna S. Dzhuriak , Mykhailo V. Vovk

{"title":"Polyfunctional dithiocarbamato-containing pyrroles: Synthesis and evaluation of antimicrobial and antioxidant activities","authors":"Alina M. Grozav , Sergiy V. Kemskyi , Mariana Z. Fedoriv , Vitaliy O. Chornous , Lesya M. Saliyeva , Nataliia Yu. Slyvka , Nina D. Yakovychuk , Valentyna S. Dzhuriak , Mykhailo V. Vovk","doi":"10.1080/10426507.2025.2475948","DOIUrl":"10.1080/10426507.2025.2475948","url":null,"abstract":"<div><div>A new effective method for the synthesis of 4- and 2-dithiocarbamato methyl substituted polyfunctional pyrroles <strong>5</strong> and <strong>8</strong> that is based on reduction of the corresponding 5-chloro-4-chloromethyl-1<em>H</em>-pyrrol-3-carboxylates <strong>3</strong> and 2-bromomethyl-5-chloro-4-cyano-1<em>H</em>-pyrrol-3-carboxylates <strong>7</strong> with dithiocarbamates of alkali metals or zinc <strong>4</strong> in a solution of DMF at 50 °C has been developed. The structural composition of all synthesized compounds was established by IR, <sup>1</sup>H NMR, and <sup>13</sup>C NMR spectroscopy and chromatography combined with mass spectrometry. Then the antimicrobial activity of all synthesized compounds was checked against the bacterial strains (<em>Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922</em>, <em>Proteus vulgaris АТСС 4636</em>, <em>Pseudomonas aeruginosa АТСС 27853</em>, and <em>Klebsiella pneumoniae АТСС 13883</em>) and fungi (<em>Candida albicans АТСС 885/653</em> and <em>Aspergillus niger K9</em>). In addition, the inhibition ability of the compounds against radicals has also been checked. As can be seen from the obtained results, the MIC of the synthesized compounds against the germs ranges between 31.25 and 125 µg/mL, MBC – 31.25–250 µg/mL, and MFC – 62.5–125 µg/mL. On the other hand, the absorption value for the DPPH radicals in ethyl 5-chloro-4-cyano-2-{[(thiomorpholin-4-ylcarbonothioyl)thio]methyl}-1-methyl-1<em>H</em>-pyrrole-3-carboxylate <strong>8b</strong> was 97.3%, while for ethyl 5-chloro-4-cyano-2-({[(dimethylamino)carbonothioyl]thio}methyl)-1-butyl-1<em>H</em>-pyrrole-3-carboxylate <strong>8e</strong> it was 95.6%.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 3","pages":"Pages 313-324"},"PeriodicalIF":1.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On carbon nanocones CNCm[n] and their face index 碳纳米锥CNCm[n]及其表面指数

IF 1.4 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2025-02-01 DOI: 10.1080/10426507.2025.2456205

Shriya Negi , Vijay Kumar Bhat

引用次数: 0

Synthesis and antimicrobial evaluation of new quinazolinone derivatives containing thiourea and thiazolidine moieties 含硫脲和噻唑烷的新型喹唑啉酮衍生物的合成及抗菌性能评价

IF 1.4 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2025-02-01 DOI: 10.1080/10426507.2025.2461044

Farzaneh Yazdan Kushkoo , Hojatollah Khabazzadeh , Moj Khaleghi

{"title":"Synthesis and antimicrobial evaluation of new quinazolinone derivatives containing thiourea and thiazolidine moieties","authors":"Farzaneh Yazdan Kushkoo , Hojatollah Khabazzadeh , Moj Khaleghi","doi":"10.1080/10426507.2025.2461044","DOIUrl":"10.1080/10426507.2025.2461044","url":null,"abstract":"<div><div>With the aim of finding novel compounds with good antimicrobial activity to counteract drug resistance, a new series of quinazolinones featuring thiourea and thiazole groups was synthesized through the reaction of 4-amino-N-(4-oxo-2-phenyl-1, 2-dihydroquinazolin-3(4H)-yl)benzamide with methyl isothiocyanate and subsequent treatment with dialkyl acetylene dicarboxylate. All synthesized compounds were characterized by spectroscopic data and elemental analysis. The antimicrobial activity of synthesized compounds was evaluated against two bacteria strains (<em>Escherichia coli</em> PTCC1330; <em>Staphylococcus aureus</em> PTCC 1431) and two fungi strains (<em>Aspergillus niger</em> PTCC5010; <em>Candida albicans</em> ATCC 10231). Almost all products exhibited good antibacterial and antifungal activities which indicated that insertion of thiourea and thiazolidine moieties considerably increased the antimicrobial properties of quinazolinones. Therefore, these compounds can be good candidates for clinical treatments, avoiding possible drug resistance problems in humans.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 2","pages":"Pages 152-163"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143601261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, crystal structure and evaluation of antibacterial activity of new hybrid systems containing furan-2-one and chromen-4-thione fragments 呋喃-2-酮和铬-4-硫酮杂化体系的合成、晶体结构及抗菌活性评价

IF 1.4 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2025-02-01 DOI: 10.1080/10426507.2025.2461042

Ekaterina Mikhailovna Arzyamova , Alevtina Yur’evna Yegorova

引用次数: 0

Synthesis and characterization of diphenylether-based oxime ligands containing unilaterally substituted 1,3,4-thiadiazole groups and investigation of their some transition metal complexes 单侧取代1,3,4-噻二唑基二苯醚肟配体的合成、表征及其过渡金属配合物的研究

IF 1.4 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2025-02-01 DOI: 10.1080/10426507.2025.2456204

Ahmed Ali Jasim , Ahmed Hamdi Mirghani , Ahmed Saleem Otaiwi , Ahmet Coşkun , Hakan Tahtaci , Saban Uysal

{"title":"Synthesis and characterization of diphenylether-based oxime ligands containing unilaterally substituted 1,3,4-thiadiazole groups and investigation of their some transition metal complexes","authors":"Ahmed Ali Jasim , Ahmed Hamdi Mirghani , Ahmed Saleem Otaiwi , Ahmet Coşkun , Hakan Tahtaci , Saban Uysal","doi":"10.1080/10426507.2025.2456204","DOIUrl":"10.1080/10426507.2025.2456204","url":null,"abstract":"<div><div>In this study, we synthesized six novel oxime ligands derived from substituted 1,3,4-thiadiazoles, along with their corresponding monomeric transition metal complexes involving Co<sup>2+</sup>, Ni<sup>2+</sup>, and Cu<sup>2+</sup> ions. Comprehensive structural characterizations were then performed to analyze these compounds. To achieve this, 4-(chloroacetyl) diphenyl ether was synthesized by reacting diphenyl ether with chloroacetyl chloride using a Friedel–Crafts reaction. The starting oxime compound, (E)-N-hydroxy-2-oxo-2-(4-phenoxyphenyl)acetylmidoyl chloride, was synthesized by reacting 4-(chloroacetyl) diphenyl ether with butyl nitrite in a 1:1 molar ratio, with HCl as the catalyst. The target oxime compounds were subsequently synthesized by reacting substituted 2-amino-1,3,4-thiadiazole derivatives with (E)-N-hydroxy-2-oxo-2-(4-phenoxyphenyl)acetylmidoyl chloride, following established procedures from the literature. The structural characterizations of all synthesized organic compounds were carried out using elemental analysis, FTIR spectroscopy, <sup>1</sup>H and <sup>13</sup>C NMR spectroscopy, and mass spectrometry. The target complexes were synthesized by reacting the ligands with MCl<sub>2</sub>·nH<sub>2</sub>O salts (M = Co<sup>2+</sup>, Ni<sup>2+</sup>, Cu<sup>2+</sup>). Their structures were confirmed using FTIR spectroscopy, magnetic susceptibility measurements, elemental analysis, and ICP-OES.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 2","pages":"Pages 133-143"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143601186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review on the synthesis of thiourea-triazine hybrid derivatives and its applications primarily in biological context 硫脲-三嗪杂化衍生物的合成及其在生物领域的应用综述

IF 1.4 4区化学

Phosphorus, Sulfur, and Silicon and the Related Elements Pub Date : 2025-02-01 DOI: 10.1080/10426507.2025.2457458

Ainaa Nadiah Abd Halim , Zainab Ngaini

{"title":"Review on the synthesis of thiourea-triazine hybrid derivatives and its applications primarily in biological context","authors":"Ainaa Nadiah Abd Halim , Zainab Ngaini","doi":"10.1080/10426507.2025.2457458","DOIUrl":"10.1080/10426507.2025.2457458","url":null,"abstract":"<div><div>Thiourea and triazine are heteroatom scaffolds that have been intensively employed for structural modification, particularly in the development of new drugs and the exploration of new applications. Recent advances have initiated the concept of merging these two moieties, maximizing the potential and enhancing the properties. This review is a comprehensive compilation highlighting the various synthesis pathways of the compound comprised of both thiourea and triazine scaffolds expressed in the form of fused triazinethione as well as <em>mono</em>-, <em>bis</em>-, and <em>tris</em>-thiourea-triazine structures. The produced compounds indefinitely showed the potential to be applied to various fields and industries. While this compilation majorly highlighted the biological capabilities of the thiourea–triazine compounds, a glimpse of other material chemistry applications was also included on the basis of the respective compound as documented by precedent literature. Therefore, this review is significant for structural modification in the field of synthetic chemistry for intended applications.</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"200 2","pages":"Pages 109-132"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143601264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0