Pediatrics International最新文献_第6页

Beckwith-Wiedemann syndrome with Hirschsprung's disease and Meckel's diverticulum.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70012

Atsuhisa Fukuta, Takuya Kondo, Naonori Kawakubo, Koichiro Yoshimaru, Kouji Nagata, Toshiharu Matsuura, Tatsuro Tajiri

引用次数: 0

Revised treatment criteria for safe reduction of phototherapy for hyperbilirubinemia.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70015

Sachiko Matsui, Sota Iwatani, Hajime Nakamura, Seiji Yoshimoto

{"title":"Revised treatment criteria for safe reduction of phototherapy for hyperbilirubinemia.","authors":"Sachiko Matsui, Sota Iwatani, Hajime Nakamura, Seiji Yoshimoto","doi":"10.1111/ped.70015","DOIUrl":"https://doi.org/10.1111/ped.70015","url":null,"abstract":"Background: To evaluate the usefulness of the revised Kobe University treatment criteria for preterm hyperbilirubinemia proposed by Morioka in 2017 (2017 revised Kobe University treatment criteria), we conducted a preliminary assessment by comparing the treatment approaches and peak bilirubin levels in preterm infants before and after the adoption of the revised criteria.Methods: This single-center retrospective cohort study enrolled patients with a gestational age <32 weeks who were delivered at our institution during two periods: 2014-2015 (Original Group), during which treatment was based on the 1992 Kobe University treatment criteria; and 2017-2018 (Revised Group), during which the 2017 revised Kobe University treatment criteria were followed. We examined the frequency and duration of phototherapy, frequency of exchange transfusion (ET), and the peak levels of total bilirubin and unbound bilirubin (UB) in both groups.Results: After excluding cases of death before discharge, transfer to other hospitals, and congenital disorders, 128 and 78 patients were assigned to the Original and Revised Groups, respectively. Regardless of the postnatal period, the duration of phototherapy was significantly shorter in the Revised Group (3 [0-21] days) than in the Original Group (8 [0-36] days). The frequency of ET was similar between the two groups. There were no differences in the percentages of patients who showed peak UB levels exceeding 0.8 or 1.0 μg/dL at any postnatal week between the two groups.Conclusions: Our preliminary study suggests that the 2017 revised Kobe University treatment criteria safely reduce the duration of phototherapy in preterm infants.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70015"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors associated with early onset hypocalcemia: A retrospective cohort study. 与早发型低钙血症相关的因素：一项回顾性队列研究。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15849

Baek Sup Shin, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim

{"title":"Factors associated with early onset hypocalcemia: A retrospective cohort study.","authors":"Baek Sup Shin, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim","doi":"10.1111/ped.15849","DOIUrl":"https://doi.org/10.1111/ped.15849","url":null,"abstract":"Background: Early onset hypocalcemia, occurring within 3 days of birth, is prevalent among preterm infants. A central line is required to deliver calcium (Ca). The prediction of hypocalcemia is therefore clinically important when the requirement for initial intravascular calcium administration is anticipated.Methods: This retrospective study included preterm infants born between 2019 and 2023 with a birthweight <1500 g or a gestational age (GA) <32 weeks in a single tertiary center. Hypocalcemia was defined as serum Ca <7 mg/dL or ionized calcium (iCa) <0.8 mmol/L within 72 h after birth. Perinatal factors and laboratory test results associated with hypocalcemia were collected and analyzed.Results: Of the 348 infants, 20 died within 7 postnatal days, 22 were transferred to other hospitals, and eight were transferred from other hospitals and were thus excluded. Of 298 enrolled infants, 20 were diagnosed with hypocalcemia. In multivariate analysis, male sex, elevated day 1 phosphorus (d1P), magnesium (d1Mg) levels, and maternal premature rupture of membranes (PROM) were significant risk factors for early onset hypocalcemia. These factors, along with birthweight, a widely recognized risk factor, were used to develop predictive models for early onset hypocalcemia. Among the six suggested models, logistic regression exhibited the highest accuracy. Conversely, the random forest model outperformed others in the Youden index and area under the receiver operating characteristic curve.Conclusions: In our cohort, early onset hypocalcemia was linked to male sex, lower GA, higher d1P and d1Mg, and maternal PROM. Notably, higher d1P has not been previously reported as a risk factor.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15849"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fatal encephalopathy and congenital heart defects with MEF2C-related disorder.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15883

Yoshitaka Asagai, Naoya Morisada, Yasunobu Miki, Hiroshi Kurosawa, Azusa Maruyama, Kandai Nozu, Kenjiro Kosaki

引用次数: 0

Successful treatment with teduglutide for an adolescent with cerebral palsy accompanied by short bowel syndrome.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15894

Megumi Tsuji, Azusa Ikeda, Yu Tsuyusaki, Tomohide Goto, Mizue Iai

引用次数: 0

Marked hypercalcemia due to maxacalcitol ointment use in a patient with severe motor and intellectual disabilities.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15850

Chinami Haseyama, Kotaro Tayama, Hirohito Shima, Sayaka Kawashima, Dai Suzuki, Atsuo Kikuchi, Junko Kanno

引用次数: 0

Glucose and lipid metabolic aberrations in preterm and low birth weight infants: Associations with lifestyle-related diseases.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70003

Nobuhiko Nagano, Ichiro Morioka

{"title":"Glucose and lipid metabolic aberrations in preterm and low birth weight infants: Associations with lifestyle-related diseases.","authors":"Nobuhiko Nagano, Ichiro Morioka","doi":"10.1111/ped.70003","DOIUrl":"https://doi.org/10.1111/ped.70003","url":null,"abstract":"The concept of the developmental origins of health and disease is well established. Prenatal undernutrition, resulting from a mismatch between pre- and postnatal environments, leads to permanent changes in body composition, function, and metabolism. These changes contribute to the development of lifestyle-related diseases such as type 2 diabetes mellitus and hyperlipidemia later in life. The future risk of lifestyle-related diseases in preterm and low-birth-weight infants is closely related to a thrifty phenotype. This phenotype is characterized by an advantageous ability to survive in a low-energy environment, resulting in reduced growth potential and muscle mass. Small size and low muscle mass lead to a decrease in basal metabolism, making it easier to accumulate excess energy as body fat. This differs fundamentally from the typical clinical presentation of obesity, which occurs in a state of energy excess. Our research focuses on two main areas: (1) investigating the increase in insulin resistance due to growth patterns and persistent reduction in lean body mass in preterm and low-birth-weight infants, and (2) studying the development of subcutaneous adipose tissue during the neonatal and infant periods, along with its associated metabolic and hormonal factors. In this review, we provide detailed insights into the mechanism by which sustained decrease in lean body mass and the development of lipid/fatty acid metabolism and adipose tissue during the fetal and neonatal periods may impact the onset of lifestyle-related diseases later in life.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70003"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ruxolitinib for preventing relapse of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70032

Eri Okura, Kenichi Sakamoto, Yuta Maruyama, Koichi Hirabayashi, Shoji Saito, Ryu Yanagisawa, Yozo Nakazawa

引用次数: 0

Successful treatment of pediatric mature B-cell lymphoma with MYC and BCL6 rearrangements.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70037

Ryo Hamada, Masaki Yamamoto, Yusuke Akane, Keita Igarashi, Takeshi Tsugawa

引用次数: 0

An infantile case of successful cardiopulmonary resuscitation during prone position.