{"title":"Spontaneous bone regeneration after decompressive craniectomy performed for an infant with acute subdural hematoma.","authors":"Shungo Yamamoto, Masao Nogami, Yuichiro Muto, Takashi Katayama, Tatemi Todaka, Katsuki Hirai","doi":"10.1111/ped.70034","DOIUrl":"https://doi.org/10.1111/ped.70034","url":null,"abstract":"","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70034"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mai Matsuyama, Hayate Masubuchi, Masayo Kagami, Rika Kosaki, Goro Koinuma
{"title":"First report of a Japanese patient with Silver-Russell syndrome and cystic fibrosis.","authors":"Mai Matsuyama, Hayate Masubuchi, Masayo Kagami, Rika Kosaki, Goro Koinuma","doi":"10.1111/ped.15882","DOIUrl":"https://doi.org/10.1111/ped.15882","url":null,"abstract":"","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15882"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric epididymitis: A 20-year single-center experience of 61 cases.","authors":"Miori Kido, Shoichi Nishida, Kiyokuni Nakamura, Tsuyoshi Kuwahara, Taichi Hirotani, Ryo Tamura, Hideaki Okajima","doi":"10.1111/ped.15886","DOIUrl":"https://doi.org/10.1111/ped.15886","url":null,"abstract":"<p><strong>Background: </strong>The etiology of acute epididymitis (AE) in children remains poorly understood. This study was performed to analyze the clinical and imaging findings in children with AE.</p><p><strong>Methods: </strong>We retrospectively reviewed children with AE treated at our institute from 2003 to 2023. The patients' medical charts were reviewed to record their clinical features and radiological and laboratory data. Multiple acute episodes occurring in individual patients were also recorded.</p><p><strong>Results: </strong>In total, 61 patients with AE were identified. Their median age at first presentation was 8 years (range, 0-22 years). The duration of pain ranged from 0 to 10 days. Accompanying genitourinary anomalies (GUA) were observed in 11 (18%) patients: hypospadias in 2, anorectal malformation in 9, neurogenic bladder in 3, undescended testis in 1, and surgery for contralateral testicular torsion in 1. One patient was diagnosed with Henoch-Schönlein purpura. Urine culture results were available in 41 patients and positive in 5 (11%). Eight patients had pre-existing infection (upper respiratory infection in four, enteritis in three, and posthitis in one). Eight (13%) patients experienced more than a second episode of epididymitis, and five (62%) of these eight patients had GUA. Testicular atrophy was present in five patients, detected 2-6 months after epididymitis.</p><p><strong>Conclusion: </strong>Most cases of AE occurred in the prepubertal period, and most urine tests were negative. Recurrent epididymitis was associated with GUA. Because some patients showed signs of testicular atrophy, careful follow-up is necessary.</p>","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15886"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chiaki Nishiyama, Koji Kanno, Tomoya Hanada, Akira Yoshida, Yusuke Ito
{"title":"Liver injury related to chest compression in an adolescent with scoliosis.","authors":"Chiaki Nishiyama, Koji Kanno, Tomoya Hanada, Akira Yoshida, Yusuke Ito","doi":"10.1111/ped.70018","DOIUrl":"https://doi.org/10.1111/ped.70018","url":null,"abstract":"","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70018"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A pediatric case of Streptococcal pyogenes empyema due to the M1<sub>UK</sub> genotype.","authors":"Keiichi Koizumi, Tomohiro Saito, Ken Takada, Toshimichi Fukao, Fuminori Numano, Noboru Oyachi, Minako Hoshiai","doi":"10.1111/ped.15877","DOIUrl":"https://doi.org/10.1111/ped.15877","url":null,"abstract":"","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15877"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing long-distance medical transport with non-invasive ventilation by linking transport services: A case report.","authors":"Shinya Miura, Hideki Ohara, Mai Miyaji, Yoshihiro Igarashi, Shinano Horie, Daigo Ando","doi":"10.1111/ped.15867","DOIUrl":"https://doi.org/10.1111/ped.15867","url":null,"abstract":"","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15867"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Monitoring measurable residual disease in NUP98::NSD1-positive acute myeloid leukemia.","authors":"Ikuo Okuchi, Akira Nishimura, Takahiro Kamiya, Makiko Sasaki, Motoi Yamashita, Akihiro Hoshino, Michiko Kajiwara, Takeshi Isoda, Hirokazu Kanegane, Tomohiro Morio, Masatoshi Takagi","doi":"10.1111/ped.15859","DOIUrl":"https://doi.org/10.1111/ped.15859","url":null,"abstract":"<p><strong>Background: </strong>NUP98 fusion genes are detected in acute myeloid leukemia (AML) subgroups that have a poor prognosis. An appropriate therapeutic approach should therefore be established. Treatment intensification according to the minimal residual disease (MRD) level can lead to a better prognosis in patients with acute lymphoblastic leukemia (ALL). However, the importance of MRD monitoring in the patient with NUP98-positive AML is unclear.</p><p><strong>Methods: </strong>This study aimed to develop a digital droplet polymerase chain reaction (ddPCR) method for monitoring NUP98::NSD1-positive leukemic cells and to report its utility compared with the results of NUP98 split fluorescence in situ hybridization (FISH).</p><p><strong>Results: </strong>The results of NUP98::NSD1 ddPCR correlated with those of NUP98 split FISH and were more sensitive than NUP98 split FISH. The sensitivity of ddPCR was 0.001%, equivalent to 1 in 1 × 10<sup>5</sup> cells. The MRD level of NUP98::NSD1, measured by ddPCR, correlated well with relapse.</p><p><strong>Conclusion: </strong>The use of ddPCR to target NUP98::NSD1 chimera mRNA for MRD monitoring would be beneficial for NUP98::NSD1 AML treatment.</p>","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15859"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rate of vertical transmission of coronavirus disease 2019 and effect of maternal vaccination: A prospective cohort study.","authors":"Satoshi Matsunashi, Hiroyuki Unoki-Kubota, Takehiro Sugiyama, Kei Yamamoto, Shinsuke Ebihara, Nobuko Nishioka, Kaoru Okazaki, Izumi Honda, Kohei Kashima, Hiroko Arai, Yayoi Murano, Ichiro Morioka, Miyuki Sadatsuki, Hajime Oishi, Shinji Mochizuki, Yasushi Kaburagi, Hiroyuki Shichino, Fumihiko Namba, Norihiro Kato, Tomohisa Akamatsu","doi":"10.1111/ped.15892","DOIUrl":"https://doi.org/10.1111/ped.15892","url":null,"abstract":"<p><strong>Background: </strong>We aimed to reveal the transmission rate of coronavirus disease 2019 (COVID-19) and clinical features of congenital and neonatal COVID-19 and to disclose the efficacy of maternally transferred antibodies by maternal vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).</p><p><strong>Methods: </strong>This multicenter, prospective observational study included a comprehensive testing protocol with appropriate precautions. Mothers and infants were enrolled and classified into an active infection group (mothers with COVID-19 at delivery), a postinfection group (mothers recovered from COVID-19 during pregnancy), and a vaccination group (mothers vaccinated during pregnancy). Specimen collections, polymerase chain reaction assays, anti-SARS-CoV-2 antibody measurements, and clinical examinations were conducted for 6 months from delivery.</p><p><strong>Results: </strong>Sixty-nine mothers and 70 infants were enrolled. SARS-CoV-2 was detected in the placenta in 22% of the active infection group and in 21% of the postinfection group. Neither SARS-CoV-2 nor SARS-CoV-2-specific IgM was detected in infants. No anomalies, functional disorders, or developmental problems were observed in infants for 6 months. Compared with the postinfection group, there was a significant increase in maternally transferred antibody titers in the vaccination group according to the number of vaccinations, which was maintained for longer than the first month of life.</p><p><strong>Conclusions: </strong>Vertical transmission of COVID-19 was not observed despite a comprehensive testing protocol. SARS-CoV-2 was detected more often in the placenta, which appeared to prevent vertical transmission. Maternal vaccination increased maternally transferred antibody titers in infants and was considered immunologically efficient. Vaccination during pregnancy is considered important for preventing congenital, neonatal, and infantile COVID-19.</p>","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15892"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}