Pediatrics International最新文献_第5页

Acrodermatitis-like rash induced by infliximab in an immunoglobulin-resistant case of Kawasaki disease. 免疫球蛋白抵抗的川崎病病例中英夫利昔单抗引起的肢端皮炎样皮疹

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70062

Yusuke Morita, Daisuke Matsubara, Mitsuru Seki, Takaomi Minami, Atsuko Sato, Mayumi Komine, Toshihiro Tajima

引用次数: 0

Neuroendocrine cell hyperplasia of infancy: A noteworthy Japanese case report. 婴儿神经内分泌细胞增生：一个值得注意的日本病例报告。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15895

Keiko Funata, Naotaka Tamai, Chizuko Haga, Takako Yoshioka, Goro Koinuma

引用次数: 0

Evaluation of the effect of inhaled β₂ agonist on lung sounds of children with acute bronchiolitis. 吸入β2激动剂对急性毛细支气管炎患儿肺音影响的评价。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70053

Yu Kuramochi, Mami Ichinose, Takashi Matsushita, Takanori Kagawa, Takashi Sakama, Kota Hirai, Hiroyuki Furuya, Fumio Niimura, Hiroyuki Mochizuki

{"title":"Evaluation of the effect of inhaled β2 agonist on lung sounds of children with acute bronchiolitis.","authors":"Yu Kuramochi, Mami Ichinose, Takashi Matsushita, Takanori Kagawa, Takashi Sakama, Kota Hirai, Hiroyuki Furuya, Fumio Niimura, Hiroyuki Mochizuki","doi":"10.1111/ped.70053","DOIUrl":"https://doi.org/10.1111/ped.70053","url":null,"abstract":"Background: Discussions regarding the treatment of acute bronchiolitis are ongoing. In this study, we investigated the effects of bronchodilators in infants with viral bronchiolitis using a lung sound analysis.Methods: Subjects were hospitalized children diagnosed with viral acute bronchiolitis who received inhaled short-acting inhaled beta 2-agonist (SABA). Lung sounds were collected before and after SABA inhalation, and imaged and quantified using a dedicated analysis system to objectively evaluate the effects of SABA. Furthermore, we investigated the influence of the child's clinical symptoms (clinical score, SpO2 value, hospitalization days, etc.), past history and family history of allergic diseases on the changes in lung sounds after SABA inhalation.Results: Twenty-six children (male: female = 16: 10, median age: 11 months) participated in the study, and wheezes on the lung sound spectrogram disappeared or decreased after inhalation of SABA in 57.7% (n = 15). However, no improvement in the low-pitched sounds of the lung spectrogram was evident, and no significant change was observed in the exhalation/inspiration power ratio. Although SpO2 in the group whose wheezes improved due to SABA inhalation was significantly lower than that in the group without improvement (p = 0.008), there were no significant differences in other factors.Conclusion: The lung sound analysis confirmed that wheezes improved after SABA inhalation in half of the infants with acute viral bronchiolitis. However, since there was no improvement in clinical symptoms or low-pitched sounds, it was hypothesized that respiratory dysfunctions were caused by various mechanisms in infants with acute bronchiolitis.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70053"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Febrile infant with bacteremia caused by group B Streptococcus and coronavirus disease 2019 during the pandemic. 大流行期间由2019年B群链球菌和冠状病毒病引起的发热婴儿菌血症。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70033

Miho Ikeda, Shinsuke Mizuno, Yukari Aida, Masaaki Kugo, Yasuo Nakagishi, Masashi Kasai

引用次数: 0

Significant head and facial injuries in pediatric balance bike riders: A case series from the emergency department. 儿童平衡自行车骑手显著头部和面部损伤：急诊科病例系列。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70105

Tsuyoshi Aihara, Shunsuke Amagasa, Shima Ohnishi, Yoshiko Uchida, Satoko Uematsu

引用次数: 0

Usefulness of the starry sky liver sign for diagnosing ketotic hypoglycemia in children. 星空肝征象对儿童酮症性低血糖的诊断价值。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70109

Tomoki Sato, Ayako Sakuma, Rika Okano

{"title":"Usefulness of the starry sky liver sign for diagnosing ketotic hypoglycemia in children.","authors":"Tomoki Sato, Ayako Sakuma, Rika Okano","doi":"10.1111/ped.70109","DOIUrl":"https://doi.org/10.1111/ped.70109","url":null,"abstract":"Background: The starry sky liver (SSL) sign, which is characterized by increased visualization of the peripheral intrahepatic vasculature during ultrasound examinations, has been associated with conditions such as acute hepatitis, Burkitt's lymphoma, and prolonged starvation. This study evaluated the utility of the SSL sign for diagnosing ketotic hypoglycemia, which is a condition that presents with vomiting and is characterized by increased ketone levels and hypoglycemia.Methods: Eighty-two patients who experienced vomiting underwent an ultrasound examination of the liver, and the SSL sign was observed and scored by two pediatricians. Patients were grouped based on blood ketone (≥2.0 mmol/L or <2.0 mmol/L) and glucose (>70 mg/dL or ≤ 70 mg/dL) levels. Ultrasound images were quantitatively analyzed using the SSL index.Results: A significant association between higher SSL signs, increased ketone levels, and lower glucose levels was observed (p < 0.05). The SSL sign was more frequently observed in patients with high ketone levels or hypoglycemia. A quantitative analysis showed an inverse correlation between the SSL index and ketone levels (R = -0.361) and a positive correlation with glucose levels (R = 0.363). The SSL index indicated good diagnostic accuracy, with areas under the receiver-operating characteristic curves of 0.76 for ketone levels and 0.73 for hypoglycemia.Conclusion: The SSL sign observed with ultrasound is a useful and noninvasive indicator that can be used to diagnose ketotic hypoglycemia in pediatric patients.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70109"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intolerance of oral methotrexate in juvenile idiopathic arthritis. 口服甲氨蝶呤治疗青少年特发性关节炎的不耐受。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70112

Ai Yuda, Tomo Nozawa, Seira Hattori, Ayako Murase, Kenichi Nishimura, Ryoki Hara, Shuichi Ito

{"title":"Intolerance of oral methotrexate in juvenile idiopathic arthritis.","authors":"Ai Yuda, Tomo Nozawa, Seira Hattori, Ayako Murase, Kenichi Nishimura, Ryoki Hara, Shuichi Ito","doi":"10.1111/ped.70112","DOIUrl":"10.1111/ped.70112","url":null,"abstract":"Background: Oral methotrexate (MTX) is a cornerstone treatment for juvenile idiopathic arthritis (JIA), although adverse events (AEs) such as nausea and vomiting often impact adherence. This study examined the intolerability of MTX in patients with JIA.Methods: We retrospectively investigated MTX intolerability in 52 patients treated at our institute between April 2011 and October 2022. The target MTX dose was 10 mg/m2/week (maximum 16 mg/week) according to the Japanese clinical guidelines for JIA.Results: The median age at MTX initiation was 8.3 years, with a median maximum dose of 8.9 mg/m2/week. Of the 52 patients, 16 (31%) were started on biologics before or at the initiation of MTX, while 36 (69%) began MTX monotherapy. Fifteen (29%) patients could not reach the target MTX dose because of AEs. Thirty-six (68%) patients experienced one or more AEs, with nausea and vomiting being the most common (n = 24). Eleven patients (21%) failed to achieve or maintain remission because of intractable nausea/vomiting, and nine (17%) eventually required biologics. Among the 24 patients who experienced nausea/vomiting, 42% developed symptoms within 6 months and 67% within 12 months of MTX initiation. AEs occurred regardless of MTX dose.Conclusions: Two-thirds of patients experienced AEs with oral MTX, leading some to fail remission and require biologics. Intolerability of oral MTX was common and significantly influenced patient outcomes.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70112"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sublobar resection for pediatric intralobar pulmonary sequestration using indocyanine green fluorescence. 吲哚菁绿荧光在小儿叶内肺隔离中的叶下切除术。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15874

Ayako Takenouchi, Keita Terui, Shugo Komatsu, Satoru Oita, Yunosuke Kawaguchi, Katsuhiro Nishimura, Tomoro Hishiki

引用次数: 0

A novel in-frame deletion flanking exon 54 of the FBN1 gene in a Japanese girl with Marfan syndrome. 日本马凡氏综合征女孩FBN1基因54外显子的框架内缺失。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15857

Toshihiko Mori, Shigeto Fuse, Kazuna Hirai, Maki Katai, Hiroko Morisaki

引用次数: 0

Gradual increase of plasma protein C activity levels in infants with newborn-onset thromboembolism. 新生儿血栓栓塞患儿血浆蛋白C活性水平逐渐升高。