{"title":"Antigenicity of proteins in cooked egg powder and skim milk powder for children with egg and milk allergies.","authors":"Michihiro Naito, Teruaki Matsui, Shiro Sugiura, Komei Ito, Hidehiko Izumi","doi":"10.1111/ped.15861","DOIUrl":"https://doi.org/10.1111/ped.15861","url":null,"abstract":"","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15861"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychiatric characteristics of child survivors after the Kahramanmaraş double earthquake.","authors":"Gonca Özyurt, Gülberat Totur, Özlem Üzüm, Ezgi Karagöz Tanıgör, Cemaliye Başaran, Fatma Mutlubaş, Belde Kasap Demir, Demet Alaygut, Mehmet Zeynel Keskin, Nihal Olgaç Dündar, Aynur Akay, Secil Arslansoyu Çamlar","doi":"10.1111/ped.15830","DOIUrl":"https://doi.org/10.1111/ped.15830","url":null,"abstract":"<p><strong>Background: </strong>The two strongest earthquakes in Turkey for eight decades hit Kahramanmaraş province on February 6, 2023. This study aimed to determine psychiatric complaints, acute stress symptoms, anxiety, depression, and sleep characteristics in children who were treated in a tertiary inpatient pediatric unit after the earthquakes. They were evaluated in the fourth week after the earthquake.</p><p><strong>Methods: </strong>Trauma experiences and acute stress disorders were evaluated by child and adolescent psychiatrists, sleep characteristics were examined by the Child Sleep Habits Questionnaire (CSHQ), and the anxiety and depressive symptoms were investigated using the Revised Child Anxiety and Depression Scale (RCADS). Forty-two patients aged 1-17 were included.</p><p><strong>Results: </strong>Trauma experiences and acute stress disorder symptoms were similar for all age groups examined. There were no significant differences in RCADS or CSHQ scores based on age or gender groups. There were significant differences in RCADS scores when the children were grouped as having parental loss or not and, similarly, there were significant differences in sleep anxiety and resistance to bedtime in CSHQ between these children.</p><p><strong>Conclusion: </strong>This research offered baseline findings about psychological outcomes after these earthquakes in child survivors, and it may provide a further basis to assess the effect of psychological interventions after earthquakes. These results may offer a foundation for suitable psychological interventions for children in developing countries.</p>","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15830"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143033473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors related to parenting difficulties among caregivers of adolescents with attention-deficit/hyperactivity disorder during the COVID-19 pandemic.","authors":"Chia-Fen Wu, Tai-Ling Liu, Yu-Ping Chang, Huei-Fan Hu, Fan-Hao Chou, Cheng-Fang Yen","doi":"10.1111/ped.15887","DOIUrl":"https://doi.org/10.1111/ped.15887","url":null,"abstract":"<p><strong>Background: </strong>Caregivers of children with attention-deficit/hyperactivity disorder (ADHD) experience more parenting stress than do caregivers of children without ADHD. Evidence suggests that ADHD severity is positively associated with parenting stress. In adolescents, ADHD increases the risks of contracting Coronavirus disease 2019 (COVID-19) and having poor outcomes. This follow-up study explored the prospective and cross-sectional factors influencing parenting difficulties experienced by the caregivers of adolescents with ADHD during the COVID-19 pandemic.</p><p><strong>Methods: </strong>The following data were collected at baseline (before the outbreak of the pandemic in Taiwan): caregivers' demographic characteristics, affiliate stigma, parenting stress, depressive and anxiety symptoms, perceived ADHD causes, and adolescents' ADHD, oppositional defiant disorder (ODD), depressive, and anxiety symptoms. The following data were collected at follow-up (after the pandemic): caregivers' parenting difficulties during the pandemic, depressive and anxiety symptoms, and adolescents' ADHD symptoms.</p><p><strong>Results: </strong>Stepwise multivariate regression analysis indicated that caregivers' parenting stress and adolescents' hyperactivity and impulsivity symptoms at baseline were positively correlated with caregivers' parenting difficulties during the pandemic. Furthermore, adolescents' hyperactivity, impulsivity, and ODD symptoms at follow-up were cross-sectionally and positively correlated with caregivers' parenting difficulties during the pandemic.</p><p><strong>Conclusion: </strong>Caregivers' parenting stress and adolescents' hyperactivity, impulsivity, and ODD symptoms should be considered when developing interventions for improving caregivers' ability to manage adolescents with ADHD, particularly in relation to self-protection, learning, life changes, daily routines, and emotional well-being.</p>","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15887"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sirolimus treatment for intractable vascular anomalies (SIVA): An open-label, single-arm, multicenter, prospective trial.","authors":"Michio Ozeki, Saori Endo, Shiho Yasue, Ryuta Asada, Akiko M Saito, Hiroya Hashimoto, Shigeru Ueno, Shoji Watanabe, Motoi Kato, Kyoichi Deie, Shunsuke Nosaka, Mikiko Miyasaka, Akihiro Umezawa, Kentaro Matsuoka, Mototoshi Kato, Tatsuo Kuroda, Takanobu Maekawa, Satoshi Hirakawa, Taizo Furukawa, Shigehisa Fumino, Tatsuro Tajiri, Junkichi Takemoto, Naonori Kawakubo, Akihiro Fujino","doi":"10.1111/ped.70002","DOIUrl":"10.1111/ped.70002","url":null,"abstract":"<p><strong>Background: </strong>Intractable vascular anomalies (VAs), including vascular tumors and venous, lymphatic, and mixed malformations, often have severe symptoms and a poor prognosis, highlighting the need for new treatments. We conducted a prospective trial of sirolimus (tablet and granule forms) for the treatment of VAs.</p><p><strong>Methods: </strong>In this open-label, single-arm, multicenter trial across four Japanese institutions, patients with VAs received oral sirolimus daily, targeting a trough concentration of 5-15 ng/mL. We evaluated response rates (radiological volume changes in lesions), skin lesions, performance status, respiratory function, visceral symptoms (bleeding, pain), laboratory data, quality of life, and safety at 12, 24, and 52 weeks.</p><p><strong>Results: </strong>Thirteen patients with VAs were treated with sirolimus. Seven patients (53.8%; 95% confidence interval: 25.1%-80.8%) showed a partial radiological response at 24 weeks, with no complete responses, and 61.5% had a partial response by 12 weeks, with little subsequent change in patients who had stable disease thereafter. Improvements in skin lesions, blood coagulation, and activities of daily living were noted. Common adverse events included stomatitis, dermatitis, diarrhea, and fever.</p><p><strong>Conclusions: </strong>Sirolimus may reduce VA tissue volume and potentially improve symptoms and activities of daily living in patients with VAs.</p>","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70002"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11937875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evin Ilter Bahadur, Pınar Zengin Akkus, Mehmet Yan, Miray Yılmaz Celebi, Mine İnal Akkaya, Gökçenur Ozdemir, Remziye Baran, Nuran Celik, Asena Ayca Ozdemir, Ali Kanık, Elif Nursel Ozmert
{"title":"The risk factors for preschoolers' behavioral problems in a low/middle-income country.","authors":"Evin Ilter Bahadur, Pınar Zengin Akkus, Mehmet Yan, Miray Yılmaz Celebi, Mine İnal Akkaya, Gökçenur Ozdemir, Remziye Baran, Nuran Celik, Asena Ayca Ozdemir, Ali Kanık, Elif Nursel Ozmert","doi":"10.1111/ped.15829","DOIUrl":"https://doi.org/10.1111/ped.15829","url":null,"abstract":"<p><strong>Background: </strong>Children have a greater risk of mental health problems in low/middle-income countries. Determining the risk factors and earlier identification of young children at high risk for behavioral problems are central to cost-effective intervention with positive long-term outcomes. The aim of this study was to examine the prevalence and risk factors of behavioral problems of preschoolers in three different cities located in eastern, western, and central Türkiye, a low/middle-income country.</p><p><strong>Methods: </strong>In total, 300 children (4-6 years old) without any chronic diseases participated the study. The parents completed the Children's Behavior Checklist/4-18 (CBCL/4-18), the Children's Sleep Habits Questionnaire, the Pittsburgh Sleep Quality Index, and the Beck Depression Inventory. Daily activities were evaluated using questionnaires that were specifically developed for the present study.</p><p><strong>Results: </strong>Based on the CBCL4-18, 12.3% of children were at high risk for behavioral problems. Paternal unemployment, screen time, maternal depressive symptoms, and maternal and child sleep problems were associated with internalizing behavioral problems; maternal depressive symptoms and watching videos on touch-screen devices were associated with externalizing behavioral problems. Total behavioral problems were associated with maternal unemployment, maternal depressive symptoms, being the eldest child, and child sleep problems.</p><p><strong>Conclusion: </strong>Preventable risk factors such as daily activities and maternal mental health should be evaluated as well as sociodemographic factors among preschoolers who may be at high risk of behavioral problems. The results of this study contribute toward drawing attention to preventable risk factors in a low/middle-income country.</p>","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15829"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Çiğdem Müge Haylı, Mehmet Zeki Avci, Dilek Demir Kösem, Neşe Ataman Bor
{"title":"Development of 6-12 years-old child sleep habits scale and investigation of its psychometric properties.","authors":"Çiğdem Müge Haylı, Mehmet Zeki Avci, Dilek Demir Kösem, Neşe Ataman Bor","doi":"10.1111/ped.70020","DOIUrl":"https://doi.org/10.1111/ped.70020","url":null,"abstract":"<p><strong>Background: </strong>Sleep and sleep habits in children are important in terms of bio-psycho-social aspects. The aim of this research was to develop a new scale under the name of the evaluation of sleep and sleep habits of children aged 6-12. 600 children aged 6-12 years constituted the sample of the study.</p><p><strong>Methods: </strong>The parents of the children were asked to answer the question list in the sleep habits scale of 6-12-year-old children, in which sleep and sleep habits were evaluated, which was formed by the socio-demographic information from an expert opinion by the research team. To examine the reliability of the scale based on internal consistency, Cronbach and Omega alpha coefficients were calculated, and test-retest analysis and criterion validity were performed to determine the stability of the scale and whether it could make consistent measurements over time.</p><p><strong>Results: </strong>In the correlation coefficient used as a test-retest reliability method, there were moderate and high levels of positive and significant correlations between the scores obtained from the first and second applications. According to the criterion validity findings, a moderately positive and significant relationship was found between the scores obtained from the overall sleep habits scale and the scores obtained from the overall child sleep habits questionnaire (r = 0.61; p < 0.01).</p><p><strong>Conclusion: </strong>These results showed that the 6-12 age child sleep habits scale, which is a parent-reported scale, is a valid and reliable new scale that can evaluate sleep and sleep habits of children and screen for potential sleep problems.</p>","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70020"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of pulmonary embolism occurring with cardiopulmonary arrest after catheter ablation.","authors":"Hiroki Ishii, Yu Matsumura, Tadahiro Yoshikawa","doi":"10.1111/ped.15858","DOIUrl":"https://doi.org/10.1111/ped.15858","url":null,"abstract":"","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15858"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}