{"title":"Antigenicity of proteins in cooked egg powder and skim milk powder for children with egg and milk allergies.","authors":"Michihiro Naito, Teruaki Matsui, Shiro Sugiura, Komei Ito, Hidehiko Izumi","doi":"10.1111/ped.15861","DOIUrl":"https://doi.org/10.1111/ped.15861","url":null,"abstract":"","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15861"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychiatric characteristics of child survivors after the Kahramanmaraş double earthquake.","authors":"Gonca Özyurt, Gülberat Totur, Özlem Üzüm, Ezgi Karagöz Tanıgör, Cemaliye Başaran, Fatma Mutlubaş, Belde Kasap Demir, Demet Alaygut, Mehmet Zeynel Keskin, Nihal Olgaç Dündar, Aynur Akay, Secil Arslansoyu Çamlar","doi":"10.1111/ped.15830","DOIUrl":"https://doi.org/10.1111/ped.15830","url":null,"abstract":"<p><strong>Background: </strong>The two strongest earthquakes in Turkey for eight decades hit Kahramanmaraş province on February 6, 2023. This study aimed to determine psychiatric complaints, acute stress symptoms, anxiety, depression, and sleep characteristics in children who were treated in a tertiary inpatient pediatric unit after the earthquakes. They were evaluated in the fourth week after the earthquake.</p><p><strong>Methods: </strong>Trauma experiences and acute stress disorders were evaluated by child and adolescent psychiatrists, sleep characteristics were examined by the Child Sleep Habits Questionnaire (CSHQ), and the anxiety and depressive symptoms were investigated using the Revised Child Anxiety and Depression Scale (RCADS). Forty-two patients aged 1-17 were included.</p><p><strong>Results: </strong>Trauma experiences and acute stress disorder symptoms were similar for all age groups examined. There were no significant differences in RCADS or CSHQ scores based on age or gender groups. There were significant differences in RCADS scores when the children were grouped as having parental loss or not and, similarly, there were significant differences in sleep anxiety and resistance to bedtime in CSHQ between these children.</p><p><strong>Conclusion: </strong>This research offered baseline findings about psychological outcomes after these earthquakes in child survivors, and it may provide a further basis to assess the effect of psychological interventions after earthquakes. These results may offer a foundation for suitable psychological interventions for children in developing countries.</p>","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15830"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143033473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immaturity of gut functions and induction of tolerance during early infancy.","authors":"Yoshikazu Ohtsuka, Toshiaki Shimizu","doi":"10.1111/ped.15855","DOIUrl":"10.1111/ped.15855","url":null,"abstract":"<p><p>Tolerance to foreign molecules is primarily induced through three pathways: anergy, active suppression, and clonal deletion. The immaturity of gut functions, including digestion and barrier protection against foreign molecules during early infancy, is closely linked to the induction of tolerance. A significant number of undigested peptides can pass through leaky gut walls during this period, making it an opportune time to introduce active suppression and clonal deletion in the intestine. Increased production and expression of TGF-β and CXCL13 with lymphoid hyperplasia in early infancy can be a convenient way to introduce tolerance and immunoglobulin A (IgA) synthesis against food and other antigens to protect hosts from allergic diseases. In this article we will discuss the immaturity of gut functions and mucosal immunity in infancy and its relationship to the introduction of tolerance.</p>","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15855"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hikaru Nishida, Eri Imagawa, Toshiki Tsunogai, Naoya Saijo, Jin Ogata, Ken Sakurai, Kimihiko Oishi
{"title":"A case of Wiedemann-Steiner syndrome caused by a novel KMT2A c.8862del variant.","authors":"Hikaru Nishida, Eri Imagawa, Toshiki Tsunogai, Naoya Saijo, Jin Ogata, Ken Sakurai, Kimihiko Oishi","doi":"10.1111/ped.15873","DOIUrl":"https://doi.org/10.1111/ped.15873","url":null,"abstract":"","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15873"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A novel in-frame deletion flanking exon 54 of the FBN1 gene in a Japanese girl with Marfan syndrome.","authors":"Toshihiko Mori, Shigeto Fuse, Kazuna Hirai, Maki Katai, Hiroko Morisaki","doi":"10.1111/ped.15857","DOIUrl":"https://doi.org/10.1111/ped.15857","url":null,"abstract":"","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15857"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yu Par Khin, Nobutoshi Nawa, Yui Yamaoka, Floret Maame Owusu, Aya Abe, Takeo Fujiwara
{"title":"Association between elementary and middle school children with mixed/foreign parents and influenza vaccination in Japan.","authors":"Yu Par Khin, Nobutoshi Nawa, Yui Yamaoka, Floret Maame Owusu, Aya Abe, Takeo Fujiwara","doi":"10.1111/ped.15851","DOIUrl":"https://doi.org/10.1111/ped.15851","url":null,"abstract":"<p><strong>Background: </strong>The number of children with foreign parents is increasing in Japan; however, the percentage of these children receiving the recommended annual influenza vaccination, which must be paid for voluntarily, may be quite low. Socioeconomic status may influence voluntary vaccination decisions. This study explored the association between elementary and middle school children with mixed (either of the parents was non-Japanese) /foreign parents (both parents were non-Japanese) and influenza vaccination in Japan, stratified by household income and maternal education.</p><p><strong>Methods: </strong>We used combined data from eight cities in the Greater Tokyo area for the period from 2016 to 2019, which included 16,368 elementary and middle school students and their caregivers. Caregivers responded to questions about whether their children received influenza vaccination in the previous year and their foreign-born status. Multilevel Poisson regression was applied and further stratified by income status and maternal education.</p><p><strong>Results: </strong>Three hundred ninety-one children (2.4%) had mixed parents, and 91 (0.6%) had foreign parents. When compared with Japanese children, children with mixed (incidence risk ratio, IRR: 0.80, confidence Interval, CI: 0.71, 0.90) and foreign parents (IRR: 0.70, CI: 0.56, 0.88) were less likely to receive influenza vaccination. After stratification, children with mixed/foreign parents were less likely to receive influenza vaccination than Japanese children only in households with high income and maternal education.</p><p><strong>Conclusions: </strong>Children with mixed and foreign parents, especially in households with high socioeconomic status, had lower influenza vaccine coverage than Japanese children.</p>","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15851"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}