Pediatrics International最新文献_第2页

Two long-term WAGR syndrome survivors: The importance of managing complications. 两个长期WAGR综合征幸存者：并发症管理的重要性。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15864

Ai Kanda, Nagisa Nomoto, Ken Ebihara, Yoshitaka Iwazu, Tetsu Akimoto, Yukihiko Nakajima, Akira Shimada

引用次数: 0

A case of fetal myocardial calcification with hyperechoic area in fetal echocardiography. 胎儿超声心动图高回声区胎儿心肌钙化1例。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15868

Takeshi Sato, Yosuke Washio, Hotaka Kawai, Kenji Baba, Eriko Eto, Hisashi Masuyama, Hirokazu Tsukahara

引用次数: 0

Secondary loss-of-response associated with intolerance to Janus kinase inhibitor in a boy with ulcerative colitis.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15880

Yuka Minoura, Koji Yokoyama, Yuko Okada, Shinya Fukuda, Hideki Kumagai

引用次数: 0

Weight gain achieved by frequent feeding in Floating-Harbor syndrome: A case report.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15860

Yuto Arai, Tetsuya Okazaki, Tohru Okanishi, Shuichi Takano, Li Fu, Naomichi Matsumoto, Yoshihiro Maegaki

引用次数: 0

First report of a Japanese patient with Silver-Russell syndrome and cystic fibrosis.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15882

Mai Matsuyama, Hayate Masubuchi, Masayo Kagami, Rika Kosaki, Goro Koinuma

引用次数: 0

Detection of anti-neuronal cell-surface antigen antibodies in pediatric patients with acute encephalitis in Japan. 日本小儿急性脑炎患者抗神经元细胞表面抗原抗体的检测。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15865

Yoshiki Kawamura, Yasuaki Mizutani, Mao Asakura, Ryunosuke Nagao, Akihiro Ueda, Hirohisa Watanabe, Tetsushi Yoshikawa

引用次数: 0

A pediatric case of Streptococcal pyogenes empyema due to the M1_UK genotype. 由M1UK基因型引起的儿童化脓性链球菌脓胸1例。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15877

Keiichi Koizumi, Tomohiro Saito, Ken Takada, Toshimichi Fukao, Fuminori Numano, Noboru Oyachi, Minako Hoshiai

引用次数: 0

Enhancing long-distance medical transport with non-invasive ventilation by linking transport services: A case report. 通过连接运输服务加强无创通气的远程医疗运输：1例报告。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15867

Shinya Miura, Hideki Ohara, Mai Miyaji, Yoshihiro Igarashi, Shinano Horie, Daigo Ando

引用次数: 0

Monitoring measurable residual disease in NUP98::NSD1-positive acute myeloid leukemia.

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15859

Ikuo Okuchi, Akira Nishimura, Takahiro Kamiya, Makiko Sasaki, Motoi Yamashita, Akihiro Hoshino, Michiko Kajiwara, Takeshi Isoda, Hirokazu Kanegane, Tomohiro Morio, Masatoshi Takagi

{"title":"Monitoring measurable residual disease in NUP98::NSD1-positive acute myeloid leukemia.","authors":"Ikuo Okuchi, Akira Nishimura, Takahiro Kamiya, Makiko Sasaki, Motoi Yamashita, Akihiro Hoshino, Michiko Kajiwara, Takeshi Isoda, Hirokazu Kanegane, Tomohiro Morio, Masatoshi Takagi","doi":"10.1111/ped.15859","DOIUrl":"https://doi.org/10.1111/ped.15859","url":null,"abstract":"Background: NUP98 fusion genes are detected in acute myeloid leukemia (AML) subgroups that have a poor prognosis. An appropriate therapeutic approach should therefore be established. Treatment intensification according to the minimal residual disease (MRD) level can lead to a better prognosis in patients with acute lymphoblastic leukemia (ALL). However, the importance of MRD monitoring in the patient with NUP98-positive AML is unclear.Methods: This study aimed to develop a digital droplet polymerase chain reaction (ddPCR) method for monitoring NUP98::NSD1-positive leukemic cells and to report its utility compared with the results of NUP98 split fluorescence in situ hybridization (FISH).Results: The results of NUP98::NSD1 ddPCR correlated with those of NUP98 split FISH and were more sensitive than NUP98 split FISH. The sensitivity of ddPCR was 0.001%, equivalent to 1 in 1 × 105 cells. The MRD level of NUP98::NSD1, measured by ddPCR, correlated well with relapse.Conclusion: The use of ddPCR to target NUP98::NSD1 chimera mRNA for MRD monitoring would be beneficial for NUP98::NSD1 AML treatment.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15859"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors associated with early onset hypocalcemia: A retrospective cohort study. 与早发型低钙血症相关的因素：一项回顾性队列研究。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15849

Baek Sup Shin, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim

{"title":"Factors associated with early onset hypocalcemia: A retrospective cohort study.","authors":"Baek Sup Shin, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim","doi":"10.1111/ped.15849","DOIUrl":"https://doi.org/10.1111/ped.15849","url":null,"abstract":"Background: Early onset hypocalcemia, occurring within 3 days of birth, is prevalent among preterm infants. A central line is required to deliver calcium (Ca). The prediction of hypocalcemia is therefore clinically important when the requirement for initial intravascular calcium administration is anticipated.Methods: This retrospective study included preterm infants born between 2019 and 2023 with a birthweight <1500 g or a gestational age (GA) <32 weeks in a single tertiary center. Hypocalcemia was defined as serum Ca <7 mg/dL or ionized calcium (iCa) <0.8 mmol/L within 72 h after birth. Perinatal factors and laboratory test results associated with hypocalcemia were collected and analyzed.Results: Of the 348 infants, 20 died within 7 postnatal days, 22 were transferred to other hospitals, and eight were transferred from other hospitals and were thus excluded. Of 298 enrolled infants, 20 were diagnosed with hypocalcemia. In multivariate analysis, male sex, elevated day 1 phosphorus (d1P), magnesium (d1Mg) levels, and maternal premature rupture of membranes (PROM) were significant risk factors for early onset hypocalcemia. These factors, along with birthweight, a widely recognized risk factor, were used to develop predictive models for early onset hypocalcemia. Among the six suggested models, logistic regression exhibited the highest accuracy. Conversely, the random forest model outperformed others in the Youden index and area under the receiver operating characteristic curve.Conclusions: In our cohort, early onset hypocalcemia was linked to male sex, lower GA, higher d1P and d1Mg, and maternal PROM. Notably, higher d1P has not been previously reported as a risk factor.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15849"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0