Pediatrics International最新文献_第2页

Pediatric esophageal foreign bodies: A toddler case of double coin ingestion. 小儿食道异物：幼儿双硬币食入1例。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15884

Taichi Maruyama, Yuko Fujii, Takahito Inoue

引用次数: 0

The risk factors for preschoolers' behavioral problems in a low/middle-income country. 中低收入国家学龄前儿童行为问题的危险因素。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15829

Evin Ilter Bahadur, Pınar Zengin Akkus, Mehmet Yan, Miray Yılmaz Celebi, Mine İnal Akkaya, Gökçenur Ozdemir, Remziye Baran, Nuran Celik, Asena Ayca Ozdemir, Ali Kanık, Elif Nursel Ozmert

{"title":"The risk factors for preschoolers' behavioral problems in a low/middle-income country.","authors":"Evin Ilter Bahadur, Pınar Zengin Akkus, Mehmet Yan, Miray Yılmaz Celebi, Mine İnal Akkaya, Gökçenur Ozdemir, Remziye Baran, Nuran Celik, Asena Ayca Ozdemir, Ali Kanık, Elif Nursel Ozmert","doi":"10.1111/ped.15829","DOIUrl":"https://doi.org/10.1111/ped.15829","url":null,"abstract":"Background: Children have a greater risk of mental health problems in low/middle-income countries. Determining the risk factors and earlier identification of young children at high risk for behavioral problems are central to cost-effective intervention with positive long-term outcomes. The aim of this study was to examine the prevalence and risk factors of behavioral problems of preschoolers in three different cities located in eastern, western, and central Türkiye, a low/middle-income country.Methods: In total, 300 children (4-6 years old) without any chronic diseases participated the study. The parents completed the Children's Behavior Checklist/4-18 (CBCL/4-18), the Children's Sleep Habits Questionnaire, the Pittsburgh Sleep Quality Index, and the Beck Depression Inventory. Daily activities were evaluated using questionnaires that were specifically developed for the present study.Results: Based on the CBCL4-18, 12.3% of children were at high risk for behavioral problems. Paternal unemployment, screen time, maternal depressive symptoms, and maternal and child sleep problems were associated with internalizing behavioral problems; maternal depressive symptoms and watching videos on touch-screen devices were associated with externalizing behavioral problems. Total behavioral problems were associated with maternal unemployment, maternal depressive symptoms, being the eldest child, and child sleep problems.Conclusion: Preventable risk factors such as daily activities and maternal mental health should be evaluated as well as sociodemographic factors among preschoolers who may be at high risk of behavioral problems. The results of this study contribute toward drawing attention to preventable risk factors in a low/middle-income country.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15829"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surviving bilateral renal agenesis: Upper intestinal atresias preserving lung development without severe oligohydramnios. 幸存的双侧肾发育不全：上肠闭锁保留肺发育，没有严重的羊水过少。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15891

Ryo Nishimaki, Sota Iwatani, Takao Kobayashi, Shoko Tamaki, Shizu Murakami, Tadashi Hatakeyama, Seiji Yoshimoto

引用次数: 0

Immaturity of gut functions and induction of tolerance during early infancy. 婴儿期早期肠道功能不成熟和诱导耐受性。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15855

Yoshikazu Ohtsuka, Toshiaki Shimizu

引用次数: 0

A case of Wiedemann-Steiner syndrome caused by a novel KMT2A c.8862del variant. 一种新的KMT2A c.8862del变异引起的Wiedemann-Steiner综合征1例。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15873

Hikaru Nishida, Eri Imagawa, Toshiki Tsunogai, Naoya Saijo, Jin Ogata, Ken Sakurai, Kimihiko Oishi

引用次数: 0

Retrospective evaluation of mild encephalitis/encephalopathy with a reversible splenial lesion in children. 儿童轻度脑炎/脑病伴可逆性脾损害的回顾性评价。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15869

Xin Li, Suzhen Sun, Huifeng Zhang

{"title":"Retrospective evaluation of mild encephalitis/encephalopathy with a reversible splenial lesion in children.","authors":"Xin Li, Suzhen Sun, Huifeng Zhang","doi":"10.1111/ped.15869","DOIUrl":"https://doi.org/10.1111/ped.15869","url":null,"abstract":"Background: Comprehensive documentation on consecutive years of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) in children is lacking. This study aims to provide an in-depth analysis of the clinical profiles of MERS in children across different age groups, focusing on pathogens and recovery time.Methods: In this retrospective study, 43 patients diagnosed with MERS were enrolled between December 2017 and November 2021. Due to different clinical manifestations at different ages, we categorized them into two age groups: the 6-year-old or younger group and the over 6-year-old group. Clinical data were described and compared for these age cohorts.Results: Sixty percent of the cases occurred during winter, with two distinct peaks in onset age, at 1-3 years of age and 7-8 years of age. Intestinal infections were prevalent among children aged below 6 years, mainly caused by rotavirus; convulsion was the most common symptom (92.6% vs. 50%, p = 0.005). Conversely, respiratory tract infections were often observed in children older than 6 years of age, which were mainly attributed to mycoplasma pneumonia; headache and dizziness were characteristic symptoms (62.5% vs. 18.5%, p = 0.003). No significant differences were found in treatment outcomes between the two age groups. Nonetheless, MERS type II exhibited a notably longer clinical recovery time than type I (4.8 ± 1.7 vs. 8.2 ± 5.5).Conclusion: Mild encephalitis/encephalopathy with a reversible splenial lesion exhibits a distinct seasonal pattern with varied clinical manifestations across different age groups. Although the prognosis was favorable, discernible differences in clinical symptoms and pathogens were observed between the two age cohorts. It was noted that the clinical recovery time for MERS type II was comparatively protracted in comparison with type I.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15869"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Liver function trends in children with suspected drug-induced hepatocellular injury: A survey using an electronic medical records database. 疑似药物性肝细胞损伤儿童的肝功能趋势：一项使用电子病历数据库的调查

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15847

Masayoshi Nakakuni, Kosuke Nakano, Ayano Inui, Shinji Kobayashi, Naoko Deguchi, Seiji Mitsui, Takeshi Kuriyama, Seiko Miyazaki

{"title":"Liver function trends in children with suspected drug-induced hepatocellular injury: A survey using an electronic medical records database.","authors":"Masayoshi Nakakuni, Kosuke Nakano, Ayano Inui, Shinji Kobayashi, Naoko Deguchi, Seiji Mitsui, Takeshi Kuriyama, Seiko Miyazaki","doi":"10.1111/ped.15847","DOIUrl":"https://doi.org/10.1111/ped.15847","url":null,"abstract":"Background: Drug-induced liver injury (DILI) is a common adverse drug event with limited pediatric data in the literature. This study aimed to use pediatric electronic medical records to assess hepatocellular DILI in pediatric patients who were prescribed liver-injury-inducing drugs.Methods: The Pediatric Medical Information Collection System (P-MICS) is a centralized database integrating electronic medical records from over 40 medical pediatric centers. Pediatric patients in the P-MICS with serum alanine aminotransferase (ALT) levels five or more times the upper limit of normal and who were below 15 years of age were selected. Those with liver diseases unrelated to drug-induced causes were excluded. We identified drugs prescribed 2 to 90 days before the first elevated ALT reading. High-risk liver-injury-causing drugs were determined based on the LiverTox score. We analyzed post-event ALT and total bilirubin levels (TB) and DILI management.Results: Of the 817 patients with suspected DILI, 251 were prescribed four drugs identified as high-risk drugs for hepatocellular DILI: methotrexate (n = 129), aspirin (n = 82), vancomycin (n = 58), and cyclophosphamide (n = 51). The median ALT level at the first event was 245 U/L. Approximately 35% of methotrexate users and cyclophosphamide users experienced recurrent ALT elevation. Some methotrexate users also showed TB elevation. Discontinuation of high-risk drugs resulted in fewer relapses and TB elevations than pharmacotherapy.Conclusions: The P-MICS effectively identifies pediatric patients with potential liver injury and tracks liver function in those prescribed liver-injury-causing drugs. This study underscores liver injury risks in pediatric anticancer drug users, highlighting the utility of the P-MICS in monitoring off-label drug safety in children.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e15847"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistent candidemia and Candida endophthalmitis with relapsed acute lymphoblastic leukemia. 复发的急性淋巴细胞白血病伴有持续性念珠菌血症和念珠菌眼内炎。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15878

Yukihiro Matsukawa, Yuri Sawada, Yuhachi Ikeda, Takashi Taga

引用次数: 0

Sublobar resection for pediatric intralobar pulmonary sequestration using indocyanine green fluorescence. 吲哚菁绿荧光在小儿叶内肺隔离中的叶下切除术。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.15874

Ayako Takenouchi, Keita Terui, Shugo Komatsu, Satoru Oita, Yunosuke Kawaguchi, Katsuhiro Nishimura, Tomoro Hishiki

引用次数: 0

A novel in-frame deletion flanking exon 54 of the FBN1 gene in a Japanese girl with Marfan syndrome. 日本马凡氏综合征女孩FBN1基因54外显子的框架内缺失。