Pediatrics International最新文献_第10页

Severe contact dermatitis associated with chlorhexidine gluconate-impregnated gel dressing. 严重接触性皮炎与葡萄糖酸氯己定浸渍凝胶敷料有关。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70081

Soichiro Wada, Shigetoshi Ogiwara, Takuya Tamura, Ryuji Shichinohe

引用次数: 0

Vitamin K deficiency bleeding and optimal prophylaxis methods in biliary atresia: A surveillance study in Japan. 胆道闭锁的维生素K缺乏性出血和最佳预防方法：日本的一项监测研究。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70075

Ryuji Okubo, Chiyoe Shirota, Motoshi Wada, Masato Shinkai, Hirofumi Tomita, Satoshi Umeda, Hiromu Miyake, Toshiharu Matsuura, Shigehisa Fumino, Akio Odaka, Taizo Hibi, Toshio Harumatsu, Akiko Yokoi, Tomoro Hishiki, Shigeru Ono, Kohei Matsushita

{"title":"Vitamin K deficiency bleeding and optimal prophylaxis methods in biliary atresia: A surveillance study in Japan.","authors":"Ryuji Okubo, Chiyoe Shirota, Motoshi Wada, Masato Shinkai, Hirofumi Tomita, Satoshi Umeda, Hiromu Miyake, Toshiharu Matsuura, Shigehisa Fumino, Akio Odaka, Taizo Hibi, Toshio Harumatsu, Akiko Yokoi, Tomoro Hishiki, Shigeru Ono, Kohei Matsushita","doi":"10.1111/ped.70075","DOIUrl":"10.1111/ped.70075","url":null,"abstract":"Background: Vitamin K (VK) prophylaxis refers to the administration of VK to newborns to prevent neonatal VK deficiency bleeding (VKDB), which is characterized by intracranial hemorrhage (ICH). This study investigated the relationship between VK prophylaxis methods and VKDB in biliary atresia (BA).Methods: The survey targeted 497 cases in the Japanese Biliary Atresia Registry between 2015 and 2019, of which 395 (79.5%) returned the questionnaire. Of the 395 patients, 289 were selected after excluding cases in which the gestational age was <36 weeks or the VK prophylaxis methods/feeding contents were unknown. The patients were categorized into two groups according to VK prophylaxis methods. We conducted a comparative study using propensity score matching. The prognosis of patients with or without ICH was also investigated.Results: In the analysis, no VKDB occurred in patients using the 3-month method. In the propensity score matching analysis, age at first visit and age at surgery were later in the three-times method (p = 0.018 and p = 0.022, respectively); VKDB was higher in the three-times method than in the 3-month method (p = 0.029). ICH, jaundice disappearance, cholangitis, and native liver survival rates (NLSRs) were not significantly different between groups. When examining the prognosis based on ICH occurrence, the two groups showed no significant differences in jaundice disappearance, cholangitis, and NLSRs. The ICH group had a greater number of cases of delayed mental and/or motor development.Conclusions: In BA, the 3-month method is effective in preventing VKDB, and early diagnosis is crucial.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70075"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144102348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is it possible to predict the spontaneous reduction of pediatric intussusception using biomarkers? 是否有可能用生物标志物来预测小儿肠套叠的自发性减少？

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70141

Emel Ulusoy, Oktay Ulusoy, Nazlı Sütçüoğlu, Tuncay Küme, Nihan Şık, Durgül Yılmaz, Murat Duman

{"title":"Is it possible to predict the spontaneous reduction of pediatric intussusception using biomarkers?","authors":"Emel Ulusoy, Oktay Ulusoy, Nazlı Sütçüoğlu, Tuncay Küme, Nihan Şık, Durgül Yılmaz, Murat Duman","doi":"10.1111/ped.70141","DOIUrl":"https://doi.org/10.1111/ped.70141","url":null,"abstract":"Background: Intussusception is one of the most common causes of acute abdominal pain in childhood. In this study, we hypothesized that alpha-glutathione S-transferase (alpha-GST), intestinal fatty acid-binding protein (IFAB), and inflammatory markers may predict spontaneous reduction in ileocolic intussusceptions, thereby preventing unnecessary interventions.Methods: A single-center, prospective case-control study was conducted in the Pediatric Emergency Department. Patients with ileocolic intussusception were categorized into three subgroups: spontaneous reduction, hydrostatic reduction, and those requiring surgery. Levels of Alpha-GST, IFABP, and routine inflammatory markers were measured prior to intervention.Results: A total of 52 cases of intussusception and 26 control patients were included in the study. Spontaneous reduction occurred in seven patients, while 45 patients required intervention. A statistically significant difference was observed between the patient and control groups regarding Alpha-GST, C-reactive protein (CRP), white blood cell count, neutrophil count, and the neutrophil-to-lymphocyte ratio (NLR). However, IFABP did not show a statistically significant difference. Alpha-GST, NLR, and CRP levels were significantly higher in the group requiring intervention than in the spontaneous reduction group.Conclusion: This study demonstrates that Alpha-GST, NLR, and CRP may predict spontaneous reduction in cases of intussusception and thereby minimize the need for unnecessary interventions.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70141"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144541854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peritoneal dialysis in an ELBW infant after resolution of hemoperitoneum: Challenges with peritonitis and cellulitis. 腹膜积血解决后，ELBW婴儿腹膜透析：腹膜炎和蜂窝织炎的挑战。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70128

Bo-Rong Chen, Yin-Ting Chen, Shang-Po Shen

引用次数: 0

An infant with achondroplasia worsening of the foramen magnum stenosis during early vosoritide treatment. 一个软骨发育不全的婴儿在早期vosoritide治疗期间枕骨大孔狭窄恶化。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70089

Yuki Gunji, Ryoji Aoki, Nobuhiko Nagano, Masako Aoki, Aya Okahashi, Koichiro Sumi, Ichiro Morioka

引用次数: 0

Congenital diaphragmatic hernia with congenital heart disease including ventricular septal defect: Risk factors. 先天性膈疝合并先天性心脏病包括室间隔缺损：危险因素。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70126

Yuichi Hirano, Keita Terui, Wataru Kudo, Ayako Takenouchi, Shugo Komatsu, Satoru Oita, Hiroko Yoshizawa, Takashi Fumita, Yusaku Yoshino, Tomoro Hishiki

{"title":"Congenital diaphragmatic hernia with congenital heart disease including ventricular septal defect: Risk factors.","authors":"Yuichi Hirano, Keita Terui, Wataru Kudo, Ayako Takenouchi, Shugo Komatsu, Satoru Oita, Hiroko Yoshizawa, Takashi Fumita, Yusaku Yoshino, Tomoro Hishiki","doi":"10.1111/ped.70126","DOIUrl":"10.1111/ped.70126","url":null,"abstract":"Background: Congenital diaphragmatic hernia (CDH) with congenital heart disease (CHD) has a poor prognosis. This study aimed to establish the prognostic factors of CDH associated with ventricular septal defect (VSD), which is the most commonly encountered CHD.Methods: We conducted a single-center, retrospective observational study including neonatal cases of CDH with CHD managed at our hospital between 2000 and 2022. The risk factors for CDH in patients with VSD were established by comparing survivors and non-survivors.Results: Among the 84 infants with CDH, 14 (17%) were associated with CHD, including 11 cases of VSD (79% of CHD). The survival rate of patients with CDH prenatally diagnosed with left-sided disease and VSD was 56% (four of nine patients died). The rate of low lung volume (observed/expected lung area-to-head circumference ratio ≤ 35%) was significantly higher in non-survivors than in survivors (75% vs. 0%, p = 0.048). All non-survivors had associated severe CHD (n = 3) or severe pulmonary hypertension (n = 1).Conclusion: Low lung volume was a risk factor for CDH with at least moderate to small size of VSD, which was comparable with that in patients with isolated CDH.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70126"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical features, diagnostic approach, and outcome of imperforate hymen: A single institution case series. 处女膜闭锁的临床特征，诊断方法和结果：单一机构病例系列。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70011

Masashi Kadohisa, Masaki Horiike, Hisanori Fujino, Takafumi Nonogaki, Narito Takada

{"title":"Clinical features, diagnostic approach, and outcome of imperforate hymen: A single institution case series.","authors":"Masashi Kadohisa, Masaki Horiike, Hisanori Fujino, Takafumi Nonogaki, Narito Takada","doi":"10.1111/ped.70011","DOIUrl":"10.1111/ped.70011","url":null,"abstract":"Background: Imperforate hymen is uncommon but it is one of the most common obstructive lesions of the female genital tract. Hydro/hematometrocolpos, derived from retained uterine and vaginal secretions and menstrual blood, causes various nonspecific symptoms. This study aimed to examine the clinical features, diagnostic approach, and outcomes of imperforate hymen at a single institution in Japan.Methods: We retrospectively reviewed all patients with imperforate hymen at Osaka Red Cross Hospital between January 2012 and November 2023.Results: Six patients were identified. Five patients were diagnosed at puberty (range: 10-13 years) and one was diagnosed in the neonatal period. A neonatal case was diagnosed incidentally during the follow-up of labial fusion. In the adolescent cases, various initial symptoms (e.g., lower abdominal pain, lower back pain, urinary retention, constipation, and abdominal distension) caused the first visit to various clinical departments, such as Internal Medicine, Emergency, Pediatrics, Obstetrics and Gynecology, Orthopedics, and Surgery. In all cases, a large cystic lesion in the lower abdomen, suggestive of hematometrocolpos, was easily detected by abdominal ultrasonography, which resulted in consultation with the appropriate clinical department or performance of additional imaging tests, such as magnetic resonance imaging, in some cases. All patients were treated with a hymenectomy or hymenotomy and circumferential suture at the vaginal introitus. Postoperative stenosis or reclosure during follow-up was not observed.Conclusions: Physicians should consider imperforate hymen as a possible diagnosis when examining adolescent girls who have not yet had menarche and present with refractory lower abdomen-related symptoms, and abdominal ultrasonography should be performed.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70011"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Avoidant/restrictive food intake disorder prognosis and its relation with autism spectrum disorder in Japanese children. 日本儿童回避/限制性食物摄入障碍预后及其与自闭症谱系障碍的关系。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70040

Chie Tanaka, Ayumi Okada, Mana Hanzawa, Chikako Fujii, Yoshie Shigeyasu, Akiko Sugihara, Makiko Horiuchi, Takashi Yorifuji, Hirokazu Tsukahara

{"title":"Avoidant/restrictive food intake disorder prognosis and its relation with autism spectrum disorder in Japanese children.","authors":"Chie Tanaka, Ayumi Okada, Mana Hanzawa, Chikako Fujii, Yoshie Shigeyasu, Akiko Sugihara, Makiko Horiuchi, Takashi Yorifuji, Hirokazu Tsukahara","doi":"10.1111/ped.70040","DOIUrl":"10.1111/ped.70040","url":null,"abstract":"Background: There is a lack of reported clinical factors associated with the outcomes of children and adolescents with avoidant/restrictive food intake disorder (ARFID) in Japan. This study aimed to identify these clinical factors and explore the relationship between ARFID and autism spectrum disorder (ASD).Methods: This retrospective study analyzed data from 48 Japanese children and adolescents with ARFID who visited Okayama University Hospital between January 2011 and March 2022. Clinical characteristics were assessed using medical records and natural history questionnaires. The study compared patients with good and poor prognosis groups and used multiple logistic regression analysis to determine factors influencing prognosis.Results: The study included 33 patients with good prognoses and 15 with poor prognoses. Comorbid ASD was more prevalent in the poor prognosis group (60%) compared to the good prognosis group (21%). Additionally, more than half of the ARFID patients with comorbid ASD were initially undiagnosed. Multivariate analysis revealed that older age at first visit (p = 0.022) and comorbid ASD (p = 0.022) were statistically significant factors associated with poor prognosis in ARFID patients. There were no significant differences in body mass index standard deviation score and maximal weight loss between the two groups.Conclusions: The poor prognosis group had a higher prevalence of comorbid ASD diagnoses. Therefore, it is crucial to evaluate patient's developmental characteristics early in treatment and consider these characteristics throughout the course of care.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70040"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12076533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lich-Gregoir vs. Cohen ureteral re-implantation surgery for bilateral vesicoureteral reflux: A propensity score analysis. Lich-Gregoir与Cohen输尿管再植入术治疗双侧膀胱输尿管反流：倾向评分分析

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70010

Takayuki Fujii, Hiroyuki Satoh, Atsuko Sato, Yoshiaki Ishizuka, Mizuki Izawa, Yuki Morimoto, Ryuichi Shimono

{"title":"Lich-Gregoir vs. Cohen ureteral re-implantation surgery for bilateral vesicoureteral reflux: A propensity score analysis.","authors":"Takayuki Fujii, Hiroyuki Satoh, Atsuko Sato, Yoshiaki Ishizuka, Mizuki Izawa, Yuki Morimoto, Ryuichi Shimono","doi":"10.1111/ped.70010","DOIUrl":"10.1111/ped.70010","url":null,"abstract":"Background: The Lich-Gregoir procedure for bilateral vesicoureteral reflux (VUR) is limited by the risk of urinary retention. Here, we investigated the efficacy of the Lich-Gregoir procedure compared to that of the Cohen procedure for bilateral VUR in children.Methods: We retrospectively evaluated children who underwent open ureteral re-implantation for bilateral VUR between 2010 and 2022. The patients' clinical characteristics and perioperative outcomes were compared after 1:1 propensity score matching (PSM).Results: A total of 137 patients were enrolled in this study, with 122 undergoing the Cohen procedure and 15 undergoing the Lich-Gregoir procedure. After PSM, there were 14 patients in each group. The operative time was shorter in the Lich-Gregoir group (121.0 vs. 157.0 min; p = 0.018), while the urethral Foley stay was longer in the Cohen group (6.0 vs. 4.0 days; p < 0.001). Only the Cohen group required ureteral catheter insertion (4.5 days) and had a higher rate of bladder spasms (85.7% vs. 0%; p < 0.001). The Cohen group experienced two postoperative complications, while the Lich-Gregoir group had one patient with temporary urinary retention. The hospitalization period was longer in the Cohen group (8.0 vs. 7.0 days; p < 0.001). There were no significant differences in postoperative hydronephrosis, postoperative urinary tract infection, and persistent VUR between the two groups.Conclusions: The Lich-Gregoir procedure for bilateral VUR was safely and effectively performed in patients who met several criteria (e.g., toilet-trained patients, mild-to-moderate reflux, and normal bladder volume and function).","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70010"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative predictors of worsened respiratory status after patent ductus arteriosus ligation in preterm infants. 早产儿动脉导管未闭结扎术后呼吸状况恶化的术前预测因素。

IF 1 4区医学

Pediatrics International Pub Date : 2025-01-01 DOI: 10.1111/ped.70030

Hyo Ju Yang, Seul Gi Park, Soo Yeon Lim, Seh Hyun Kim, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim

{"title":"Preoperative predictors of worsened respiratory status after patent ductus arteriosus ligation in preterm infants.","authors":"Hyo Ju Yang, Seul Gi Park, Soo Yeon Lim, Seh Hyun Kim, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim","doi":"10.1111/ped.70030","DOIUrl":"10.1111/ped.70030","url":null,"abstract":"Background: Preterm infants with hemodynamically significant patent ductus arteriosus (PDA) may require surgical ligation. Following the surgery, some infants may encounter a deterioration in respiratory status. This study aimed to evaluate the risk factors that can predict worsened respiratory outcomes after PDA surgical ligation.Methods: A retrospective cohort study was performed on 57 preterm infants born at less than 32 weeks of gestational age and in whom the PDA was surgically ligated between January 2014 and December 2018 at Seoul National University Children's Hospital. Participants were divided into two groups: infants with worsened respiratory outcomes 14 days after ligation and control. Worsened respiratory outcome was defined as an increase in respiratory severity score (RSS) by 30% or more at 14 days after ligation compared to RSS before ligation, or death at 14 days after ligation.Results: Among the 57 PDA-ligated infants, 12 had worsened respiratory outcomes and 45 did not. The worsened respiratory outcomes were associated with oligohydramnios (adjusted OR 1.38, 95% CI 1.1-1.73, p < 0.01) and lower weight at surgery (adjusted OR 0.99, 95% CI 0.99-0.99, p = 0.02), compared to the control.Conclusion: Worsened respiratory outcomes after PDA ligation appeared to be associated with oligohydramnios, and lower weight on the day of surgery.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"67 1","pages":"e70030"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0