Pediatrics International最新文献_第10页

Nationwide daily exclusive breastfeeding rates during birth hospitalization in Japan. 日本出生住院期间全国每日纯母乳喂养率。

IF 0.9 4区医学

Pediatrics International Pub Date : 2026-01-01 DOI: 10.1111/ped.70374

Tsuyoshi Isojima, Noriko Kato, Naho Morisaki, Shiro Sugiura, Akinori Moriichi, Tetsuji Yokoyama

{"title":"Nationwide daily exclusive breastfeeding rates during birth hospitalization in Japan.","authors":"Tsuyoshi Isojima, Noriko Kato, Naho Morisaki, Shiro Sugiura, Akinori Moriichi, Tetsuji Yokoyama","doi":"10.1111/ped.70374","DOIUrl":"https://doi.org/10.1111/ped.70374","url":null,"abstract":"Objective: Breast milk provides optimal nutrition for infants, with exclusive breastfeeding recommended for the first 6 months of life. Education during birth hospitalization is vital to promote exclusive breastfeeding. However, standardized references for neonatal weight loss rates based on data including national representative, multi-hospital, with different policies remain unavailable.Methods: Data of 4774 participants from 146 hospitals throughout Japan were obtained from the national growth survey. Among them, 3302 were eligible for the analysis. Daily exclusive breastfeeding rates and their associations with facility and individual characteristics during birth hospitalization were then analyzed. Additionally, weight loss percentile reference curves by delivery mode were established using the Lambda-Mu-Sigma method.Results: The rate was 60.8% on day 0 and plateaued at approximately 25% on day 3. Being born in a facility with high exclusive breastfeeding rate (odds ratio [OR]: 333.3, 95% confidence interval [CI]: 15.2-7142, p < 0.0001), multiparity (OR: 1.9, 95% CI: 1.4-2.5, p < 0.0001), vaginal delivery (OR: 2.2, 95% CI: 1.6-3.1, p < 0.0001), and lower weight loss rate on day 3 (OR: 1.2, 95% CI: 1.1-1.2, p < 0.0001) were identified as independent factors, and facility-level differences accounted for 58.4% of the total variability for exclusive breastfeeding at discharge. Using the data from 831 neonates with exclusive breastfeeding at discharge, weight loss rate references were established.Conclusion: This study revealed Japan's nationwide daily exclusive breastfeeding rates during birth hospitalization and their significant influencing factors. The established references may be useful in promoting exclusive breastfeeding clinically.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"68 1","pages":"e70374"},"PeriodicalIF":0.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147468815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between QTA30 scores and headache-related assessments in children. QTA30评分与儿童头痛相关评估的关系

IF 0.9 4区医学

Pediatrics International Pub Date : 2026-01-01 DOI: 10.1111/ped.70387

Toshiyuki Hikita, Hideki Hoshino, Masakazu Mimaki

{"title":"Association between QTA30 scores and headache-related assessments in children.","authors":"Toshiyuki Hikita, Hideki Hoshino, Masakazu Mimaki","doi":"10.1111/ped.70387","DOIUrl":"https://doi.org/10.1111/ped.70387","url":null,"abstract":"Background: The QTA30 is a simple questionnaire used to assess physical and mental health in children. Headache-related disability and impact are commonly evaluated using the Pediatric Migraine Disability Assessment (PedMIDAS) and the Headache Impact Test-6 (HIT-6). This study examined the relationship between physical and mental health assessed by the QTA30 and headache-related assessments in pediatric patients.Method: This study included patients who visited Hikita Pediatric Clinic from April 2023 to March 2025 and completed the QTA30, PedMIDAS, and HIT-6. Associations between assessment scores were analyzed using Spearman's rank correlation coefficient.Results: A total of 68 patients were included, with a median age of 13 years (range: 6-17); 43 were female. The median total QTA30 score was 37 (range: 4-78), the median PedMIDAS score was 15.5 days (range: 0-148), and the median HIT-6 score was 62.5 (range: 26-78). The total QTA30 score showed a moderate positive correlation with PedMIDAS (r = 0.4, p = 0.0007). In contrast, no significant correlation was observed between the total QTA30 score and HIT-6 (r = 0.11, p = 0.36). The physical symptoms subscale of the QTA30 demonstrated a strong positive correlation with PedMIDAS (r = 0.51, p < 0.0001), while the anxiety subscale was also positively correlated with PedMIDAS (r = 0.31, p = 0.0091).Conclusions: Physical and mental health measures assessed by the QTA30 were associated with PedMIDAS, which reflects headache-related disability and duration, but not with HIT-6, which primarily reflects headache intensity.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"68 1","pages":"e70387"},"PeriodicalIF":0.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful management of pulmonary artery sling and severe tracheal stenosis in an extremely low birth weight infant. 1例极低出生体重儿肺动脉悬吊及严重气管狭窄的成功治疗。

IF 0.9 4区医学

Pediatrics International Pub Date : 2026-01-01 DOI: 10.1111/ped.70357

Yasuhiro Ohta, Hiroyuki Ikeda, Yui Ueda, Chiharu Sudo, Satoshi Toishi

引用次数: 0

Analysis of intracellular organelles in neurons differentiated from iPSCs of Chédiak-Higashi syndrome patients. ch<s:1> - higashi综合征患者iPSCs分化神经元胞内细胞器的分析。

IF 0.9 4区医学

Pediatrics International Pub Date : 2026-01-01 DOI: 10.1111/ped.70326

Yasuko Nakamura, Masataka Ito, Akira Senoo, Shigeharu Oh, Akira Niwa, Yu Hashimoto, Hidetoshi Hagiwara, Yasuhiro Uemura, Tadataka Tsuji, Hidenori Ohnishi, Yasuo Horikoshi, Akira Shiraishi, Yumi Oshiro, Masataka Ishimura, Ryo Hanaki, Masahiro Hirayama, Kohsuke Imai, Osamu Ohara, Megumu K Saito, Ikuroh Ohsawa, Shigeaki Nonoyama

{"title":"Analysis of intracellular organelles in neurons differentiated from iPSCs of Chédiak-Higashi syndrome patients.","authors":"Yasuko Nakamura, Masataka Ito, Akira Senoo, Shigeharu Oh, Akira Niwa, Yu Hashimoto, Hidetoshi Hagiwara, Yasuhiro Uemura, Tadataka Tsuji, Hidenori Ohnishi, Yasuo Horikoshi, Akira Shiraishi, Yumi Oshiro, Masataka Ishimura, Ryo Hanaki, Masahiro Hirayama, Kohsuke Imai, Osamu Ohara, Megumu K Saito, Ikuroh Ohsawa, Shigeaki Nonoyama","doi":"10.1111/ped.70326","DOIUrl":"https://doi.org/10.1111/ped.70326","url":null,"abstract":"Background: Clinical manifestations of Chédiak-Higashi syndrome (CHS), an autosomal recessive disorder caused by LYST gene variants, include immunodeficiency and neurologic deficits. This study investigated the effects of defective LYST on neurodegenerative features by the morphological analysis of organelles in dopaminergic neurons differentiated from induced pluripotent stem cells (iPSCs) derived from CHS patients.Methods: iPSCs derived from CHS patients were analyzed by immunostaining with antibodies against microtubule-associated protein 2 and tyrosine hydroxylase, periodic acid-Schiff (PAS) staining, electron microscopy, and staining with a fluorescent probe to monitor autophagy.Results: iPSC-derived neurons contained PAS-positive giant granules and lipofuscin-like granules. Electron microscopy revealed enlarged lysosomes with electron-dense granules and filament-like structures. The number and brightness of autophagosomes and autolysosomes were markedly increased in CHS iPSC-derived neurons under basal culture conditions. CHS iPSC-derived neuronal mitochondria were enlarged, polymorphic, and hypertrophic.Conclusions: CHS iPSC-derived neurons contained abnormal organelles, including lysosomes, autophagosomes, and mitochondria, which may be related to the neurodegenerative features of CHS.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"68 1","pages":"e70326"},"PeriodicalIF":0.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146213750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transcutaneous and precordial Doppler ultrasonography to confirm correct intraosseous access placement: A case report. 经皮及心前多普勒超声确认正确的骨内通道放置：1例报告。

IF 0.9 4区医学

Pediatrics International Pub Date : 2026-01-01 DOI: 10.1111/ped.70336

Tomoki Ueda, Yuji Hirayama, Tomoya Ito, Taiki Kojima

引用次数: 0

Antimicrobial stewardship program at a long-term care facility for severely disabled children and adults. 在严重残疾儿童和成人长期护理机构的抗菌药物管理计划。

IF 0.9 4区医学

Pediatrics International Pub Date : 2026-01-01 DOI: 10.1111/ped.70314

Nobuhiro Kanie, Yasuko Kudo, Koji Fukano, Masako Igari, Wakana Furushima, Ayaka Koide, Tetsuji Kaneko, Yoshihiko Morikawa, Sho Ishii, Kazuhiro Uda, Kahoru Fukuoka-Araki, Yuho Horikoshi

{"title":"Antimicrobial stewardship program at a long-term care facility for severely disabled children and adults.","authors":"Nobuhiro Kanie, Yasuko Kudo, Koji Fukano, Masako Igari, Wakana Furushima, Ayaka Koide, Tetsuji Kaneko, Yoshihiko Morikawa, Sho Ishii, Kazuhiro Uda, Kahoru Fukuoka-Araki, Yuho Horikoshi","doi":"10.1111/ped.70314","DOIUrl":"https://doi.org/10.1111/ped.70314","url":null,"abstract":"Background: The implementation of the antimicrobial stewardship program (ASP) has become a standard practice aimed at optimizing antimicrobial prescriptions to prevent further development of drug-resistant organisms. However, the challenges faced in long-term care facilities (LTCFs) often present a scarcity of human resources crucial for the effective implementation of ASP initiatives. Our study was to evaluate the impact of feasible ASP in the LTCF.Methods: A quasi-experimental study was conducted at the Tokyo Metropolitan Fuchu Medical Center for the Disabled serving as a LTCF in Japan. The pre- and post-intervention periods were from April 2013 to March 2018 and from April 2018 to March 2019, respectively. Multidisciplinary ASP, including periodic educational interventions, utilization of internal treatment manuals, pre-authorization, and prospective audit and feedback on prescribing practices, was administered by the infectious diseases team from the Tokyo Metropolitan Children's Medical Center. We compared days of antimicrobial therapy (DOT) and resistance rates between the pre- and post-intervention phases.Results: Following the intervention, there was a noteworthy decline in the use of oral broad-spectrum antimicrobials (macrolides, fluoroquinolones, and third-generation cephalosporins), demonstrating a statistically significant level of change (p < 0.05). Throughout the study period, resistance rates of Escherichia coli and Pseudomonas aeruginosa to meropenem and levofloxacin remained largely stable, with no notable changes observed.Conclusion: In this study, extending the expertise of antimicrobial stewardship from an adjoining acute-care facility to a LTCF was associated with a 42% reduction in the use of oral broad-spectrum antimicrobials.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"68 1","pages":"e70314"},"PeriodicalIF":0.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pneumothorax as a life-threatening long-term complication with mucolipidosis type II. 气胸是危及生命的长期粘脂病II型并发症。

IF 0.9 4区医学

Pediatrics International Pub Date : 2026-01-01 DOI: 10.1111/ped.70318

Shion Tomari, Hiroyuki Iijima, Goro Koinuma, Motomichi Kosuga, Kensuke Shoji, Mitsuru Kubota

引用次数: 0

Cerebral blood flow and benzodiazepine receptor distribution in a patient with ALG6-congenital disorder of glycosylation. 先天性糖基化障碍alg6患者的脑血流和苯二氮卓受体分布。

IF 0.9 4区医学

Pediatrics International Pub Date : 2026-01-01 DOI: 10.1111/ped.70324

Ryuki Matsuura, Kenjiro Kikuchi, Azusa Oba, Hirofumi Ohashi, Nobuhiko Okamoto

引用次数: 0

Presentation of hyperekplexia during the newborn period: Is there any additional treatment option to clonazepam? 新生儿期出现过度增生：除氯硝西泮外是否有其他治疗选择？