Pediatrics International最新文献_第10页

Epidemiology of pediatric inflammatory bowel disease categorized by age subgroups in Korea. 韩国按年龄分组的小儿炎症性肠病流行病学。

IF 1 4区医学

Pediatrics International Pub Date : 2024-01-01 DOI: 10.1111/ped.15786

Yeong Eun Kim, Seo-Hee Kim, Seong Pyo Kim, Yujin Park, Su Hwan Kim, Sung Hee Lee, Ho Jung Choi, In Sook Jeong, Seak Hee Oh, Hyung-Jin Yoon, Kyung Mo Kim

{"title":"Epidemiology of pediatric inflammatory bowel disease categorized by age subgroups in Korea.","authors":"Yeong Eun Kim, Seo-Hee Kim, Seong Pyo Kim, Yujin Park, Su Hwan Kim, Sung Hee Lee, Ho Jung Choi, In Sook Jeong, Seak Hee Oh, Hyung-Jin Yoon, Kyung Mo Kim","doi":"10.1111/ped.15786","DOIUrl":"https://doi.org/10.1111/ped.15786","url":null,"abstract":"Background: Pediatric inflammatory bowel disease (PIBD) affects different age groups and its incidence is increasing worldwide. However, there is a lack of research focusing on age subgroups in Asian countries. In this nationwide population-based study, we investigated the epidemiology of PIBD among different age subgroups in Korea.Methods: We analyzed Korean health administration data from 2005 to 2016. Data were divided by age at diagnosis as follows: group 1, 0-1 years; group 2, 2-5 years; group 3, 6-9 years; group 4, 10-16 years. We analyzed the overall incidence, temporal changes, and regional differences by age subgroups, using Poisson regression analysis.Results: From 2005 to 2016, 2734 inflammatory bowel disease (IBD) cases were diagnosed among patients under 17 years of age. In the overall population, the incidence rate of PIBD over the entire study period was 2.248/105 person-years (PY), significantly increasing from 1.173/105 PY in 2005-2007 to 3.267/105 PY in 2014-2016. The incidence rates in groups 1 and 2 remained unchanged, whereas those of groups 3 and 4 increased significantly. The same trend was observed when analyzed separately for Crohn's disease (CD) and ulcerative colitis (UC). The incidence rates of CD in groups 3 and 4 showed differences between metropolitan and non-metropolitan areas, whereas those in groups 1 and 2, and UC of all age subgroups showed no difference.Conclusions: The temporal trend and regional differences of PIBD differed among age subgroups, suggesting that genetic and environmental factors have varying impacts on IBD development across different subgroups.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"66 1","pages":"e15786"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142004955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Late onset group B streptococcal disease in a single center, Saitama, Japan, 2011-2023. 2011-2023 年日本琦玉县一家中心的晚发性 B 群链球菌病。

IF 1.4 4区医学

Pediatrics International Pub Date : 2024-01-01 DOI: 10.1111/ped.15745

Takuto Kasai, Takahiro Tominaga, Kazushige Ikeda

引用次数: 0

Successful treatment of Sweet syndrome complicated by Behcet disease with adalimumab. 阿达木单抗成功治疗斯威特综合征并发白塞氏病。

IF 1 4区医学

Pediatrics International Pub Date : 2024-01-01 DOI: 10.1111/ped.15815

Maho Hatano, Shuya Kaneko, Hitoshi Irabu, Masaki Shimizu

引用次数: 0

Metaphyseal anadysplasia type 1: Familial and regressive rickets manifestation. 骺软骨发育不全 1 型：家族性和退行性佝偻病表现。

IF 1 4区医学

Pediatrics International Pub Date : 2024-01-01 DOI: 10.1111/ped.15766

Hideki Matsumoto, Tomohiro Hori, Mai Mori, Hideo Sasai, Tsuyoshi Tokuyama, Takahiro Yamada, Hidenori Ohnishi

引用次数: 0

Japanese siblings with multicentric osteolysis nodulosis and arthropathy. 患有多中心骨溶解结节病和关节病的日本兄妹。

IF 1.4 4区医学

Pediatrics International Pub Date : 2024-01-01 DOI: 10.1111/ped.15743

Seigo Okada, Eitaro Suzuki, Yasuo Suzuki, Tadashi Moriwake, Kosei Hasegawa, Ayumi Omuro, Shunji Hasegawa

引用次数: 0

Impact of social distancing policy on pediatric emergency ophthalmic severity during the coronavirus disease 2019 pandemic. 在 2019 年冠状病毒疾病大流行期间，社会距离政策对儿科急诊眼科严重程度的影响。

IF 1 4区医学

Pediatrics International Pub Date : 2024-01-01 DOI: 10.1111/ped.15845

Hyung Kyoo Woo, Seung Ah Chung, Hyelynn Jeon, Bumhee Park, Jung Heon Kim

{"title":"Impact of social distancing policy on pediatric emergency ophthalmic severity during the coronavirus disease 2019 pandemic.","authors":"Hyung Kyoo Woo, Seung Ah Chung, Hyelynn Jeon, Bumhee Park, Jung Heon Kim","doi":"10.1111/ped.15845","DOIUrl":"10.1111/ped.15845","url":null,"abstract":"Background: We investigated the impact of social distancing policies (SDPs) on ophthalmic severity in children who underwent emergency ophthalmic referrals during the coronavirus disease 2019 pandemic period.Methods: We reviewed all children with ophthalmic referrals in a single academic hospital emergency department during the period from February 2017 to December 2019 (prepandemic) or February 2020 to December 2022 (pandemic). Baseline features, diagnosis-based severity, and outcomes were compared between the two periods. The Government Response Stringency Index (GRSI), which ranges from 0 to 100, was used as a surrogate for the intensity of SDPs during the pandemic. Poisson regression was used to quantify the association of the GRSI with the severity.Results: Among 1074 children with ophthalmic referrals, 437 (40.7%) visited during the pandemic. This was 31.4% lower than that during the prepandemic period. In numbers, pandemic-related declines were more modest in high severity than in medium-to-low severity (35.1% vs. 55.0%), and for injury than for illness (28.5% vs. 36.1%). In percentages, high severity increased from 63.3% to 71.3% (p = 0.016). The hospitalization rate increased from 1.7% to 3.9% (p = 0.029). For every 10-point increase in GRSI, there was a 20.0% decrease in high severity (95% confidence interval, 5%-30%).Conclusions: This study shows an inverse association of SDPs with ophthalmic severity and an increase in severe cases along with consistent flow of injury cases, amid the overall decline in eye-related visits to the emergency department during the pandemic period.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"66 1","pages":"e15845"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11580109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142472362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biotinidase biochemical and molecular analyses: Experience at a large reference laboratory. 生物素酶生化和分子分析：大型参考实验室的经验。

IF 1.4 4区医学

Pediatrics International Pub Date : 2024-01-01 DOI: 10.1111/ped.15726

Rajesh Sharma, Cathlin R Kucera, Camille R Nery, Felicitas L Lacbawan, Denise Salazar, Pranoot Tanpaiboon

{"title":"Biotinidase biochemical and molecular analyses: Experience at a large reference laboratory.","authors":"Rajesh Sharma, Cathlin R Kucera, Camille R Nery, Felicitas L Lacbawan, Denise Salazar, Pranoot Tanpaiboon","doi":"10.1111/ped.15726","DOIUrl":"10.1111/ped.15726","url":null,"abstract":"Background: Biotinidase deficiency is caused by absent activity of the biotinidase, encoded by the biotinidase gene (BTD). Affected individuals cannot recycle the biotin, leading to heterogeneous symptoms that are primarily neurological and cutaneous. Early treatment with biotin supplementation can prevent irreversible neurological damage and is recommended for patients with profound deficiency, defined as enzyme activity <10% mean normal (MN). Molecular testing has been utilized along with biochemical analysis for diagnosis and management. In this study, our objective was to correlate biochemical phenotype/enzyme activity to BTD genotype in patients for whom both enzyme and molecular testing were performed at our lab, and to review how the correlations inform on variant severity.Methods: We analyzed results of biotinidase enzyme analysis and BTD gene sequencing in 407 patients where samples were submitted to our laboratory from 2008 to 2020.Results: We identified 84 BTD variants; the most common was c.1330G>C, and 19/84 were novel BTD variants. A total of 36 patients had enzyme activity <10% of MN and the most common variant found in this group was c.528G>T. No variant was reported in one patient in the profound deficiency group. The most common variant found in patients with enzyme activity more than 10% MN was c.1330G>C.Conclusions: Although enzyme activity alone may be adequate for diagnosing profound biotinidase deficiency, molecular testing is necessary for accurate carrier screening and in cases where the enzyme activity falls in the range where partial deficiency and carrier status cannot be discriminated.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"66 1","pages":"e15726"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139651399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post COVID-19 condition and behavioral manifestations in Taiwanese children. 台湾儿童 COVID-19 后的状况和行为表现。

IF 1.4 4区医学

Pediatrics International Pub Date : 2024-01-01 DOI: 10.1111/ped.15724

Chia-Jung Li, Hong-Ren Yu, Kuang-Che Kou, Wen-Jiun Chou, Ching-Shu Tsai, Liang-Jen Wang

{"title":"Post COVID-19 condition and behavioral manifestations in Taiwanese children.","authors":"Chia-Jung Li, Hong-Ren Yu, Kuang-Che Kou, Wen-Jiun Chou, Ching-Shu Tsai, Liang-Jen Wang","doi":"10.1111/ped.15724","DOIUrl":"10.1111/ped.15724","url":null,"abstract":"Background: This study investigated the prevalence of post COVID-19 condition (PCC) in Taiwanese children, explored common symptoms and behavioral manifestations in children with PCC, and examined potential associations with parental stress and family functioning.Methods: A total of 116 children who had contracted COVID-19 and their parents participated. At 1 month after the confirmed COVID-19 infection (baseline), the parents were asked to complete a questionnaire about the post COVID-19 symptoms, the child behavior checklist (CBCL) based on the child's situation, also the impact event scale of COVID-19 (IES-C) and family APGAR based on the parents' own situation. Three months after the confirmed COVID-19 infection, parents were again asked to complete the same questionnaires as they did at baseline.Results: Results showed that 44.8% of the children met the criteria for PCC, with the most common symptoms being sputum/nasal congestion, tiredness and decreased concentration. Children without PCC exhibited a significant decrease in CBCL scores during the 2-month follow-up, while no such decrease was observed in children with PCC. However, no significant correlations were found between the number of post COVID-19 symptoms, behavioral manifestations, parental stress levels, and family functioning.Conclusions: Children with PCC have a less favorable trajectory in improving their behavioral manifestations. Additionally, in the post-pandemic era, post COVID-19 symptoms in children are not necessarily correlated with parental stress and family functioning. Further research is needed to better understand the long-term implications of PCC in children and its impact on their mental well-being, as well as their families.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"66 1","pages":"e15724"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139058506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute internal carotid artery occlusion in a girl with leukemia. 一名白血病女孩的急性颈内动脉闭塞。

IF 1 4区医学

Pediatrics International Pub Date : 2024-01-01 DOI: 10.1111/ped.15765

Shotaro Ogawa, Satoshi Koizumi, Satoshi Kiyofuji, Hikoro Matsui, Nobuhito Saito

引用次数: 0

Successful endoscopic approach for peripheral neuroblastic tumors in children. 成功采用内窥镜方法治疗儿童外周神经母细胞瘤。

IF 1 4区医学

Pediatrics International Pub Date : 2024-01-01 DOI: 10.1111/ped.15754

Naonori Kawakubo, Junnosuke Maniwa, Keiko Irie, Akihiko Tamaki, Atsuhisa Fukuta, Ryota Souzaki, Satoshi Obata, Kouji Nagata, Toshiharu Matsuura, Tatsuro Tajiri

{"title":"Successful endoscopic approach for peripheral neuroblastic tumors in children.","authors":"Naonori Kawakubo, Junnosuke Maniwa, Keiko Irie, Akihiko Tamaki, Atsuhisa Fukuta, Ryota Souzaki, Satoshi Obata, Kouji Nagata, Toshiharu Matsuura, Tatsuro Tajiri","doi":"10.1111/ped.15754","DOIUrl":"https://doi.org/10.1111/ped.15754","url":null,"abstract":"Background: Recently, reports of endoscopic approaches for neuroblastoma, ganglioneuroblastoma, and ganglioneuroma (peripheral neuroblastic tumor; PNTs) have been increasing. This study aimed to clarify the indications for endoscopic surgery for PNTs.Methods: Pediatric patients who underwent endoscopic surgery for PNTs at our institution were included in this study. Image-defined risk factors (IDRFs) were analyzed using preoperative computed tomography (CT).Results: Twenty-four patients underwent endoscopic surgery for PNTs. The diagnoses included neuroblastoma (n = 11), ganglioneuroma (n = 10), and ganglioneuroblastoma (n = 3). Regarding the tumor site, there were 18 cases of adrenal tumors, five cases of mediastinal tumors, and one case of retroperitoneal tumors. Image-defined risk factors were positive in eight cases (contacted with a renal vessel, n = 6; compression of principal bronchi, n = 2). Complete resection was accomplished in 21 cases (14 of 16 IDRF-negative cases and seven of eight IDRF-positive cases). All patients survived without recurrence during the follow-up period.Conclusions: The CT findings of contact with renal vessels and compression of principal bronchi do not seem to be indicators of incomplete resection. An endoscopic approach to PNTs in pediatric patients is feasible with a good prognosis if patients are selected strictly.","PeriodicalId":20039,"journal":{"name":"Pediatrics International","volume":"66 1","pages":"e15754"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141458688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0