Pediatric Cardiology最新文献_第5页

Brachiocephalic Vein Duplication: Case Report of a Double Left Brachiocephalic Vein in an Infant. 肱脑静脉重复：婴儿双左侧肱脑静脉的病例报告。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-04-01 Epub Date: 2024-06-21 DOI: 10.1007/s00246-024-03552-3

Alyssa Marcum, Nita Ray Chaudhuri, Salwa Gendi

引用次数: 0

Trends in Tetralogy of Fallot-Related Mortality in the United States Between 1999 and 2020. 1999年至2020年美国法洛特四联症相关死亡率趋势

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-31 DOI: 10.1007/s00246-025-03846-0

Obaid Ur Rehman, Eeshal Fatima, Adeena Jamil, Zain Ali Nadeem, Aimen Nadeem, Ahmed Kamal Siddiqi, Richard A Krasuski

{"title":"Trends in Tetralogy of Fallot-Related Mortality in the United States Between 1999 and 2020.","authors":"Obaid Ur Rehman, Eeshal Fatima, Adeena Jamil, Zain Ali Nadeem, Aimen Nadeem, Ahmed Kamal Siddiqi, Richard A Krasuski","doi":"10.1007/s00246-025-03846-0","DOIUrl":"https://doi.org/10.1007/s00246-025-03846-0","url":null,"abstract":"We sought to identify mortality trends related to Tetralogy of Fallot (ToF) in the U.S. population, with specific emphasis on age-related, racial, and geographic differences. Death certificate data was retrieved from the CDC WONDER database, where crude mortality rate (CMR) and age-adjusted mortality rates (AAMR) with 95% CIs per 1,000,000 population were identified, along with annual percentage changes (APCs) and average annual percentage change (AAPC) determined by Joinpoint regression. From 1999 to 2020, a total of 5523 deaths were reported in association with ToF, with nearly half of all deaths occurring during the first year of life. The AAMR steadily decreased from 1999 to 2020 (AAPC: - 1.26, 95% CI - 2.29 to -0.38, p-value = 0.012). Males had a slightly higher AAMR (0.91) than females (0.77). Non-Hispanic (NH) Blacks/African Americans had a higher AAMR (1.00) compared with NH Whites (0.83). Infants less than a year old exhibited the highest CMRs among all age groups. Although lower rates were seen among all age strata < 45 years of age, deaths in patients > 45 years significantly increased from 2013 to 2020 (APC 6.17, 95% CI 0.79 to 20.35, p-value = 0.047). Rural areas consistently exhibited greater AAMRs and lesser declines over time compared to urban areas, with most deaths occurring in medical facilities. Over the last 2 decades in the US, the mortality rates associated with ToF have steadily decreased. Focusing resources on these higher risk populations may prove beneficial.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital Cardiac Catheterization Risk Assessment in Infants Under 2.5 kg. 2.5 公斤以下婴儿的先天性心导管风险评估。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-28 DOI: 10.1007/s00246-025-03821-9

Michael L O'Byrne, Nicholas S Boscamp, Kimberlee Gauvreau, Grace R Rahman, Oliver M Barry, Sarosh P Batlivala, Lisa Bergersen, Elsa C Bjornlund, Martin L Bocks, Thomas Doyle, Michael Farias, Bryan H Goldstein, Ralf J Holzer, Suren R Veeram Reddy, Arash Salavitabar, Shyam Sathanandam, Wendy Whiteside, Brian P Quinn

{"title":"Congenital Cardiac Catheterization Risk Assessment in Infants Under 2.5 kg.","authors":"Michael L O'Byrne, Nicholas S Boscamp, Kimberlee Gauvreau, Grace R Rahman, Oliver M Barry, Sarosh P Batlivala, Lisa Bergersen, Elsa C Bjornlund, Martin L Bocks, Thomas Doyle, Michael Farias, Bryan H Goldstein, Ralf J Holzer, Suren R Veeram Reddy, Arash Salavitabar, Shyam Sathanandam, Wendy Whiteside, Brian P Quinn","doi":"10.1007/s00246-025-03821-9","DOIUrl":"https://doi.org/10.1007/s00246-025-03821-9","url":null,"abstract":"Premature and small-for-gestational-age neonates with congenital heart disease increasingly require congenital cardiac catheterization (CCC). These patients present unique procedural and patient-specific risks that standard risk models do not fully capture. This study aims to assess risk in infants < 2.5 kg undergoing CCC, further stratifying by procedural type to better understand predictors of clinically meaningful adverse events (CMAE). Patient and Procedural data were collected on diagnostic and interventional catheterization procedures for infants < 2.5 kg from the Congenital Cardiac Catheterization Project on Outcomes (C3PO) registry between 2014 and 2022. Cases were stratified into historical (2014-2018) and modern (2019-2022) eras and further categorized into PDA closure and 'All Other Cases'. Multivariable logistic regression assessed associations between covariates and the risk of CMAE. Analysis included 1,345 cases. In the modern era, PDA closures (n = 898, 66.8%) had a lower CMAE rate at 3.6% versus 8.1% for 'All Other Cases' (P < 0.001). Among 'All Other Cases' (n = 447) 23% were diagnostic and 77% interventional, with CMAE rates of 7.7% and 6.4%, respectively. CMAE types varied, with PDA cases mainly experiencing respiratory events (22%) and 'All Other Cases' showing higher rates of access complications (27%) and arrhythmias (29%). Risk in infants < 2.5 kg undergoing CCC is heavily dependent on procedural type and specific patient factors, highlighting the need for tailored risk assessment tools. This study, the largest to date in this population, emphasizes the importance of individualized care plans to improve outcomes.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary Artery Size as a Predictor of Early Post-operative Pediatric and Congenital Heart Transplant Outcomes. 肺动脉大小是儿童和先天性心脏移植术后早期预后的预测因子。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-27 DOI: 10.1007/s00246-025-03839-z

William A Harris, Zain S Kazmi, John M Costello, Jason R Buckley, Minoo N Kavarana, Andrew J Savage, Varsha M Bandisode, Anthony M Hlavacek, Carolyn L Taylor

{"title":"Pulmonary Artery Size as a Predictor of Early Post-operative Pediatric and Congenital Heart Transplant Outcomes.","authors":"William A Harris, Zain S Kazmi, John M Costello, Jason R Buckley, Minoo N Kavarana, Andrew J Savage, Varsha M Bandisode, Anthony M Hlavacek, Carolyn L Taylor","doi":"10.1007/s00246-025-03839-z","DOIUrl":"https://doi.org/10.1007/s00246-025-03839-z","url":null,"abstract":"Pulmonary artery size has been studied as an outcome predictor for selected congenital heart surgeries but has not been investigated in pediatric and congenital heart transplantation. We sought to evaluate pre-operative pulmonary artery size as a predictor of post-transplant outcomes. This single center retrospective study included all patients transplanted from 2014 to 2023. Echocardiography, computed tomography angiography (CTA), and catheter angiography were used to measure pre-operative pulmonary artery size. Cross-sectional areas were calculated and indexed to calculate Nakata index and lower lobe index. Outcomes included post-transplant cardiovascular and end-organ function, length of stay, and mortality. Statistical analyses included Spearman rank correlations, chi-squared tests, and Mann-Whitney U tests. Included were 68 patients with 37 (54%) having a diagnosis of congenital heart disease. Echocardiogram (n = 68), CTA (n = 52), and catheter angiogram (n = 31) measurements were analyzed. Smaller lower lobe index was associated with longer duration of post-transplant treatment with nitric oxide (p = 0.02). In the congenital heart disease cohort, smaller Nakata index was associated with pulmonary artery reconstruction during transplant (p = 0.003). Indexed pulmonary artery size was otherwise not associated with important outcomes in the entire population or congenital heart disease cohort. While pre-operative pulmonary artery size was associated with prolonged nitric oxide use, it was generally not predictive of other early post-transplant outcomes. No imaging modality was found to have superior predictive value. Use of advanced imaging to guide surgical technique during transplant may negate the impact of smaller pulmonary artery size.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Indolent Kawasaki Disease with Delayed Coronary Artery Lesions: The Role of Proactive Imaging. 迟发性川崎病伴冠状动脉病变1例：主动影像的作用。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-27 DOI: 10.1007/s00246-025-03836-2

Koji Nishigaki, Kunihiko Takahashi, Shota Hamano, Masaki Ota, Ayuka Kato, Kyoko Noguchi, Taisuke Onoe, Shizuka Nishimoto, Makiko Kikkawa, Yasuyuki Tokunaga, Kosuke Chayama

{"title":"A Case of Indolent Kawasaki Disease with Delayed Coronary Artery Lesions: The Role of Proactive Imaging.","authors":"Koji Nishigaki, Kunihiko Takahashi, Shota Hamano, Masaki Ota, Ayuka Kato, Kyoko Noguchi, Taisuke Onoe, Shizuka Nishimoto, Makiko Kikkawa, Yasuyuki Tokunaga, Kosuke Chayama","doi":"10.1007/s00246-025-03836-2","DOIUrl":"https://doi.org/10.1007/s00246-025-03836-2","url":null,"abstract":"Kawasaki Disease (KD) is an acute vasculitis primarily affecting children and can lead to coronary artery lesions (CALs) if not promptly diagnosed and treated. Indolent KD, characterized by spontaneous fever resolution without early intervention, poses diagnostic challenges as patients may not initially meet the complete diagnostic criteria, delaying treatment and increasing the risk of CAL development. We report a case of a 17-month-old boy with indolent KD who developed CAL on the 18th day of illness, necessitating IVIG therapy. Despite initial symptom resolution, echocardiographic monitoring revealed delayed coronary artery involvement, underscoring the importance of proactive imaging. This case highlights the need for frequent echocardiographic evaluation in indolent KD, particularly when clinical and laboratory findings are inconclusive. Serial imaging facilitates early detection of CALs, enabling timely IVIG therapy and potentially preventing disease progression. A structured follow-up strategy is crucial in managing indolent KD to reduce the risk of long-term cardiovascular complications.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143720880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Largest Single-Center Experience Using the Micro Vascular Plug (MVP) for Transcatheter Closure of Premature Patent Ductus Arteriosus. 利用微血管塞（MVP）经导管关闭过早动脉导管未闭的最大单中心经验。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-27 DOI: 10.1007/s00246-025-03832-6

Peter Guyon, Dijana Popevski, Thomas Forbes, Brian Boe, Kak-Chen Chan, Larry Latson

{"title":"Largest Single-Center Experience Using the Micro Vascular Plug (MVP) for Transcatheter Closure of Premature Patent Ductus Arteriosus.","authors":"Peter Guyon, Dijana Popevski, Thomas Forbes, Brian Boe, Kak-Chen Chan, Larry Latson","doi":"10.1007/s00246-025-03832-6","DOIUrl":"https://doi.org/10.1007/s00246-025-03832-6","url":null,"abstract":"Within the last 5 years, the FDA approved use of the Amplatzer Piccolo Occluder (Abbot Structural Heart, CA) for transcatheter patent ductus arteriosus (PDA) closure in premature infants. Other devices have been used off-label to successfully perform this procedure, including the Microvascular Plug, \"MVP\" (Medtronic, Minneapolis, MN). We report the largest single-center experience with PDA closure in premature infants using the MVP device. A retrospective review of transcatheter premature infant PDA closures at a single center was performed. Procedures performed using the MVP device were included; procedures using other devices were excluded. Descriptive statistics were performed using R version 4.4.0. From 4/2018 to 8/2022, a total of 74 cases were performed. The median gestational age was 24 (IQR 23-25) weeks and procedural weight was 1.17 kg (0.97-1.40); (82% ≤ 1.5 kg). The age at procedure was 44 days (34-54). PDA minimum diameter (by angiogram) was 2.85 (2.4-3.4) mm. There were no procedural or 30-day mortalities. There was one major Adverse Event (AE) (aortic arch obstruction; 1.3%). There were two minor AEs (2.6%; small pericardial effusion requiring no intervention, n = 1; and device malposition with uneventful retrieval and replacement of additional device within the same catheterization, n = 1). The left pulmonary artery peak gradient at most recent follow-up was 5.8 (3.4-8.9) mmHg; the aortic peak gradient was 0.77 (0.4-1.7). There is a median follow-up time of 63 days (32-310) post-procedure. The safety profile using the MVP is in line with or favorable compared to the contemporary literature of PDA closure in premature infants.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143720882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

School Performance and Learning Challenges in Children and Adolescents with Congenital Heart Disease. 患有先天性心脏病的儿童和青少年的学校表现和学习挑战。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-24 DOI: 10.1007/s00246-025-03835-3

Zeina Al-Khalil, Jad Abdul Khalek, Mohamad Al Hajjar, Marc Barakat, Fadi Bitar, Mariam Arabi

{"title":"School Performance and Learning Challenges in Children and Adolescents with Congenital Heart Disease.","authors":"Zeina Al-Khalil, Jad Abdul Khalek, Mohamad Al Hajjar, Marc Barakat, Fadi Bitar, Mariam Arabi","doi":"10.1007/s00246-025-03835-3","DOIUrl":"https://doi.org/10.1007/s00246-025-03835-3","url":null,"abstract":"Children with congenital heart disease are at risk for neurocognitive and neurodevelopmental challenges, learning disabilities, and psychosocial difficulties. Our narrative review draws literature-based evidence for the effect of congenital heart disease on school performance. We conducted a literature review and extracted relevant articles from Google Scholar, Medline, and PubMed. Evidence showcases that school performance is impacted directly by congenital heart disease. This seems to be underlined by different factors inherent to congenital heart disease, like inattention, language difficulties, and decreased fine and gross motor skills. Moreover, the operative and postoperative periods present various physical challenges that can hinder development, ultimately affecting daily activities and quality of life. The consequent stressors in childhood can have long-lasting effects, leading to an increased prevalence of anxiety and depression affecting patients as they transition into adolescence and adulthood and placing significant social and emotional burdens on their direct environment. Children with congenital heart disease face both direct and indirect challenges related to their disease. These challenges are most likely to be the source of poor school performance and learning, as suggested by the literature. Close monitoring, early interventions, and multidisciplinary care are essential to address these vulnerabilities and improve educational outcomes in children with congenital heart disease.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond the Evidence: Psychological and Institutional Factors Shaping Patent Ductus Arteriosus Stent Adoption. 超越证据：心理和制度因素影响动脉导管未闭支架的采用。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-22 DOI: 10.1007/s00246-025-03837-1

Stephen T Dalby, Daniel Fiedorek, Joshua A Daily

引用次数: 0

Cost-Effectiveness of Implantable Cardioverter-Defibrillators in Surgically Repaired Tetralogy of Fallot. 植入式心律转复除颤器在外科修复法洛四联症中的成本-效果。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-21 DOI: 10.1007/s00246-025-03833-5

Christopher W Follansbee, Laura A Navarro, Brian Feingold, Gaurav Arora

{"title":"Cost-Effectiveness of Implantable Cardioverter-Defibrillators in Surgically Repaired Tetralogy of Fallot.","authors":"Christopher W Follansbee, Laura A Navarro, Brian Feingold, Gaurav Arora","doi":"10.1007/s00246-025-03833-5","DOIUrl":"https://doi.org/10.1007/s00246-025-03833-5","url":null,"abstract":"Implantable cardioverter-defibrillators (ICDs) are increasingly used in patients with congenital heart disease, most commonly in surgically repaired Tetralogy of Fallot (rTOF). Studies have examined patient outcomes after ICD implantation; however, the cost-effectiveness of ICDs in rTOF is unknown. We sought to evaluate the cost-effectiveness of typical medical management plus ICD (TMM + ICD) for primary prevention of sudden cardiac death (SCD) compared to typical management alone (TMM) in high-risk patients with rTOF. We created a Markov model to compare costs and quality of life (QOL) of TMM + ICD vs TMM for a hypothetical adolescent with rTOF and higher than average risk of SCD over 20 years. Model parameters were derived from the literature and institutional data. We assumed that SCD risk increased from 0.4%/year to 1.2%/year over 20 years, that the ICD was 99% effective in preventing SCD, and a frequency of ICD replacement of 11 years. We used sensitivity analyses to explore uncertainty around model assumptions. Costs were $62,895 for TMM + ICD and $19,004 for TMM. The incremental cost-effectiveness ratio for TMM + ICD was $53,386/quality-adjusted life-year (QALY) which is below threshold of $100,000/QALY that is usually considered cost-effective. The model was sensitive to SCD risk, costs of ICD implantation and management, cost of ICD replacement, and utilities of living with rTOF and of ICD implantation. Based on risk of SCD, cost of device implantation and management including complications, and our current understanding of the impact of ICD implantation on patient QOL, ICD therapy for primary prevention of SCD in rTOF can constitute a cost-effective strategy.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on "Contraception Use in Adolescents and Young Adults with Congenital Heart Disease". 关于“青少年和青壮年先天性心脏病患者的避孕措施使用”的评论。

IF 1.5 4区医学

Pediatric Cardiology Pub Date : 2025-03-21 DOI: 10.1007/s00246-025-03838-0

Syeda Samia Fatima

引用次数: 0