Pediatric Cardiology最新文献_第6页

Correction: Six Minute Walk Test and Clinical Outcomes in Pediatric Heart Transplant Candidates. 更正：6分钟步行试验和儿科心脏移植候选人的临床结果。

IF 1.3 4区医学

Pediatric Cardiology Pub Date : 2026-10-30 DOI: 10.1007/s00246-026-04520-9

Marcella B Richtmann, Aida Luiz R Turquetto, Luciana P Amato, Estela Azeka, Adailson W D S Siqueira, Fabio A R Goncalves, Luiz F Canêo, Marcelo B Jatene

引用次数: 0

AI-Enabled Digital Stethoscope for Early Detection of Congenital Heart Disease: Prospective Study. 人工智能数字听诊器用于先天性心脏病的早期检测：前瞻性研究

IF 1.3 4区医学

Pediatric Cardiology Pub Date : 2026-10-30 DOI: 10.1007/s00246-026-04541-4

Niharika Karandikar, Adarsh Kachappilly, Ankit Kadarge, Ali Rumane, Sameer Ansari, Shashank Bhaskaran, Tanuja Karande, Prashant Bobhate

{"title":"AI-Enabled Digital Stethoscope for Early Detection of Congenital Heart Disease: Prospective Study.","authors":"Niharika Karandikar, Adarsh Kachappilly, Ankit Kadarge, Ali Rumane, Sameer Ansari, Shashank Bhaskaran, Tanuja Karande, Prashant Bobhate","doi":"10.1007/s00246-026-04541-4","DOIUrl":"https://doi.org/10.1007/s00246-026-04541-4","url":null,"abstract":"Early detection of congenital heart disease (CHD) is critical, particularly in low- and middle-income countries where access to congenital cardiac services is limited. While auscultation remains a first-line screening tool, its accuracy is operator dependent. Advances in digital stethoscopes and artificial intelligence (AI) may enhance diagnostic performance. To evaluate the accuracy of an AI-based algorithm integrated with a digital stethoscope for detecting CHD in children and young adults, using echocardiography as the reference standard. In this prospective single centre study, heart sounds were recorded from 721 subjects (382 with CHD, 339 controls) using the digital stethoscope at four standard auscultatory sites. Of these, 301 recordings were used for algorithm training and 420 for blinded forward testing, which was divided temporally with the data collected in first 5 months used for training and the data collected after that used for forward testing. Recordings were denoised, transformed into mel-spectrograms, and analyzed using a convolutional neural network (CovNN) to classify CHD probability. A threshold probability of > 0.5 across > 2 sites was used to predict CHD. Performance was compared against echocardiography. In forward testing, the AI algorithm correctly identified 222 of 233 CHD cases and 171 of 187 controls, yielding a sensitivity of 95.2% and specificity of 91.4%. The algorithm remained effective in noisy environments and in uncooperative children, where conventional auscultation is challenging. An AI algorithm integrated with a digital stethoscope demonstrated high sensitivity and specificity for CHD detection in children and young adults. By leveraging mel-spectrogram features, it overcomes key limitations of isolated time-domain or frequency domain analysis and shows promise as a scalable, non-invasive screening tool for early CHD detection, particularly in resource-limited settings.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149299329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mental Health of Children with Fontan Circulation: Associations with Maternal Psychopathology and Parenting Behavior. 方坦循环患儿的心理健康：与母亲精神病理和父母行为的关系。

IF 1.3 4区医学

Pediatric Cardiology Pub Date : 2026-10-29 DOI: 10.1007/s00246-026-04514-7

Jonas Markus Hemetsberger, Nina Nicklin, Katharina Louisa Göttlicher, Jennifer Gerlach, Lennart Heinzel, Isabelle Schöffl, Oliver Kratz, Anna Eichler

{"title":"Mental Health of Children with Fontan Circulation: Associations with Maternal Psychopathology and Parenting Behavior.","authors":"Jonas Markus Hemetsberger, Nina Nicklin, Katharina Louisa Göttlicher, Jennifer Gerlach, Lennart Heinzel, Isabelle Schöffl, Oliver Kratz, Anna Eichler","doi":"10.1007/s00246-026-04514-7","DOIUrl":"https://doi.org/10.1007/s00246-026-04514-7","url":null,"abstract":"Children with Fontan circulation face substantial long-term psychosocial challenges. Parental mental health and parenting behavior are known to influence psychosocial outcomes in children with congenital heart disease (CHD), yet data specific for Fontan families are scarce. This cross-sectional controlled study examined child psychopathology in relation to maternal psychopathology and parenting behavior. 31 mothers and their children with Fontan circulation (aged 4-16 years) were compared with a sex-, age- and socioeconomic status (SES)- matched control group. Standardized maternal self-report questionnaires assessed child psychopathology, maternal psychopathology, and parenting behavior. Children with Fontan circulation showed significantly higher psychopathology than controls (F (1,58) = 6.38, p = .014, ηp² = 0.10). No group differences were found in maternal psychopathology or parenting behavior (all p > .24). No Group × Moderator interaction effects emerged (all p > .35). Significant main effects were observed for maternal total psychopathology, anxiety, and depression (F(1,58) = 13.10, p < .001, ηp² = 0.19; F(1,58) = 9.94, p = .003, ηp² = 0.15; F(1,58) = 11.00, p = .002, ηp²= 0.16), and inconsistent parenting behavior (F(1,58) = 19.20, p < .001, ηp² = 0.26), associated with higher child psychopathology across groups, underscoring the need for family-focused support in the Fontan population.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149299626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic Variants Associated with Ventricular Septal Defect in Malaysia: A Scoping Review of Current Evidence and Research Gaps. 遗传变异与室间隔缺损在马来西亚：目前的证据和研究差距的范围审查。

IF 1.3 4区医学

Pediatric Cardiology Pub Date : 2026-10-28 DOI: 10.1007/s00246-026-04530-7

Amanda Shen-Yee Kong, Nasirah Binti Mohamad Waziril Ghozi, Ghee Tiong Koh, Kooi Yeong Khaw, Sathiya Maran

{"title":"Genetic Variants Associated with Ventricular Septal Defect in Malaysia: A Scoping Review of Current Evidence and Research Gaps.","authors":"Amanda Shen-Yee Kong, Nasirah Binti Mohamad Waziril Ghozi, Ghee Tiong Koh, Kooi Yeong Khaw, Sathiya Maran","doi":"10.1007/s00246-026-04530-7","DOIUrl":"https://doi.org/10.1007/s00246-026-04530-7","url":null,"abstract":"Ventricular septal defect (VSD) is the most prevalent congenital heart defect in Malaysia; however, its genetic basis is still not well understood. We conducted a scoping review to evaluate the current evidence on VSD-associated genetic variants in the Malaysian population. A comprehensive literature search was conducted in PubMed, Scopus, Web of Science, and Embase from inception to June 2026, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guidelines. Original studies investigating genetic variants associated with VSD in Malaysian patients were included. Data regarding study characteristics, investigated genes, reported variants, molecular methods, and principal findings were extracted and synthesised. Out of 28 records identified, three studies met the eligibility criteria. The included studies reported variants in three genes: SMAD7, NR0B1, and NIPBL. The identified variants included synonymous substitutions and frameshift alterations that were predicted to cause premature protein truncation. However, the available evidence was limited by small sample sizes, candidate-gene approaches, and the predominance of syndromic cases. We found no nationwide or multicentre studies using high-throughput sequencing technologies. Despite the significant disease burden, the current evidence on the genetics of VSD in Malaysia remains sparse. The lack of comprehensive genomic investigations underscores the need for collaborative studies across the nation that integrate next-generation sequencing and functional validation. This would enhance our understanding of VSD pathogenesis and support future precision medicine initiatives.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149299655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Compassionate Pediatric Cardiology Program. 慈悲儿科心脏病学项目。

IF 1.3 4区医学

Pediatric Cardiology Pub Date : 2026-10-28 DOI: 10.1007/s00246-026-04529-0

Colin J McMahon, Joseph Rossano

{"title":"The Compassionate Pediatric Cardiology Program.","authors":"Colin J McMahon, Joseph Rossano","doi":"10.1007/s00246-026-04529-0","DOIUrl":"https://doi.org/10.1007/s00246-026-04529-0","url":null,"abstract":"Pediatric cardiology combines extraordinary technical complexity with profound human vulnerability. Although compassion is often regarded as an attribute of individual clinicians, its consistent delivery depends on the organizational culture and systems in which they work. We propose that compassion should be understood as an organizational competency, enabled by effective leadership, psychological safety, trust, communication, teamwork, and thoughtful system design. Across the congenital cardiac journey, children and families depend on multidisciplinary teams for clear, honest, and emotionally attuned communication. Such care is especially important during diagnosis, surgery or catheter intervention, critical illness, transplantation, adverse outcomes, end-of-life decisions, and lifelong follow-up. High workload, excessive hierarchy, fragmented services, and psychologically unsafe environments can undermine compassionate practice despite clinicians' best intentions. Conversely, supportive cultures allow professionals to acknowledge uncertainty, raise concerns, collaborate across disciplines, and respond meaningfully to family distress. We outline a practical framework for embedding compassion into pediatric cardiac programs through structured communication training, inclusive decision-making, protected family meetings, reflective debriefing, supportive leadership, and routine assessment of family and workforce experience. Implementation should be co-designed with families and staff and evaluated for feasibility, adoption, sustainability, and unintended workload consequences. This proposed framework requires prospective testing rather than assumed effectiveness. Excellent clinicians can provide compassionate care; excellent organizations create the conditions that make it reliable, measurable, and sustainable across complex and demanding settings.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149299666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Children with Single Ventricle Congenital Heart Disease: A Single-Center Experience. 钠-葡萄糖共转运蛋白2抑制剂治疗儿童单心室先天性心脏病的临床效果：一项单中心研究

IF 1.3 4区医学

Pediatric Cardiology Pub Date : 2026-10-27 DOI: 10.1007/s00246-026-04532-5

Alexander O Canova, David M Newland, Erin L Albers, Erin S Bouska, Christina L Hartje-Dunn, Mehreen S Iqbal, Mariska S Kemna, Yuk M Law, Sarah M Kerr, Bethany L Wisotzkey, Borah J Hong

{"title":"Clinical Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Children with Single Ventricle Congenital Heart Disease: A Single-Center Experience.","authors":"Alexander O Canova, David M Newland, Erin L Albers, Erin S Bouska, Christina L Hartje-Dunn, Mehreen S Iqbal, Mariska S Kemna, Yuk M Law, Sarah M Kerr, Bethany L Wisotzkey, Borah J Hong","doi":"10.1007/s00246-026-04532-5","DOIUrl":"https://doi.org/10.1007/s00246-026-04532-5","url":null,"abstract":"This study evaluates the impact of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on pediatric patients with single ventricle (SV) heart disease, using invasive and non-invasive markers of cardiac function. We reviewed patients (< 21 years) with SV physiology who received ≥ 90 days SGLT2i at our center from 2020 to 2025. Baseline laboratory, echocardiographic, and hemodynamic data were recorded and compared to follow up data after ≥ 90 days on SGLT2i. Hospitalizations before and after SGLT2i were also analyzed. Seventy-seven patients with median age 10.5 years (range 47 days-19.9 years) had median treatment duration of 386 days (IQR 218-853). Among 62 patients (81%) with echocardiographic data (Fontan [39], Glenn [18], Stage 1 [5]) there was a significant decrease in median qualitative AVVR score from mild-moderate to mild (p = 0.01). Median BNP decreased from 84 pg/mL (IQR 18-274) to 42 pg/mL (IQR 18-105) (p = 0.02) and mean hemoglobin increased from 14.4 ± 2.5 g/dL to 15.5 ± 2.4 g/dL (p < 0.01). Ten patients had hemodynamic data without significant change in mean pulmonary artery pressure from 17 to 16 mmHg (p = 0.168) or ventricular end-diastolic pressure from 10 to 11 mmHg (p = 0.275). More patients had > 1 hospitalizations for heart failure during the 6-months prior to SGLT2i compared to the 6-months following initiation, with an odds ratio of 4.5 (95% CI: 1.6-13.7, p < 0.01). Overall, we identified significant reductions in AVVR, BNP, and hospitalizations for heart failure after ≥ 90 days of therapy. Further larger scale studies are needed to determine if SGLT2i will affect clinical outcomes in the pediatric SV population.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149288186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving Efficiency in the Inpatient Echocardiography Laboratory: A Quality Improvement Project. 提高住院病人超声心动图实验室的工作效率：一项质量改进工程。

IF 1.3 4区医学

Pediatric Cardiology Pub Date : 2026-10-27 DOI: 10.1007/s00246-026-04524-5

Stefani Samples, Zhanna Roytman, Carrie McCaw, Pei-Ni Jone

{"title":"Improving Efficiency in the Inpatient Echocardiography Laboratory: A Quality Improvement Project.","authors":"Stefani Samples, Zhanna Roytman, Carrie McCaw, Pei-Ni Jone","doi":"10.1007/s00246-026-04524-5","DOIUrl":"https://doi.org/10.1007/s00246-026-04524-5","url":null,"abstract":"Pediatric echocardiograms are performed daily on inpatient hospital units. Understanding the precise study indication from ordering providers is critical for completing imaging. Given the daily volume of echocardiograms, timely completion of imaging is important for maintaining efficiency and productivity. This study sought to identify areas to improve efficiency using quality improvement methodologies. SMART aim was to decrease the total echo completion time by 10% within 6 months. Fishbone diagram identified ordering system limitations and inadequate ordering provider knowledge as areas for improvement. Primary process and outcome metrics included total echo completion time, pre-echocardiogram buffer time, and specificity in order documentation. PDSA 1 implemented electronic order updates for increased specificity with a picklist of common reasons for inpatient echocardiograms. PDSA 2 implemented an ordering alert for STAT studies to reduce the number of inappropriate orders. PDSA 3 implemented additional order updates and staff education. Total echo completion time decreased each cycle for total 34% reduction. The pre-echocardiogram buffer time similarly decreased 59%. The documentation of pertinent clinical history increased by 15% and maintained at 99% appropriate documentation for the final two PDSA cycles. Pre and post intervention surveys indicated an overall improvement in the ordering process for both the inpatient ordering providers and echocardiography laboratory staff. Echocardiography laboratory efficiency improved throughout the course of this project without identified negative effects on ordering providers or echocardiography staff. Our project demonstrates the ability to affect clinically relevant improvements utilizing simple workflow process changes in the pediatric echocardiography laboratory.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149288132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes of Handmade Tri-leaflet ePTFE Valved Conduits for RVOT Reconstruction: A Propensity-Matched Analysis Compared with PVR. 手工三瓣ePTFE带瓣导管用于RVOT重建的结果：与PVR相比的倾向匹配分析。

IF 1.3 4区医学

Pediatric Cardiology Pub Date : 2026-10-27 DOI: 10.1007/s00246-026-04533-4

Naoki Masaki, Junichi Koizumi, Yuya Yamazaki, Daichi Edaki, Kanchi Saito, Akira Sato, Yurie Takizawa, Satoshi Nakano, Hirofumi Saiki, Akio Ikai, Hajime Kin

{"title":"Outcomes of Handmade Tri-leaflet ePTFE Valved Conduits for RVOT Reconstruction: A Propensity-Matched Analysis Compared with PVR.","authors":"Naoki Masaki, Junichi Koizumi, Yuya Yamazaki, Daichi Edaki, Kanchi Saito, Akira Sato, Yurie Takizawa, Satoshi Nakano, Hirofumi Saiki, Akio Ikai, Hajime Kin","doi":"10.1007/s00246-026-04533-4","DOIUrl":"https://doi.org/10.1007/s00246-026-04533-4","url":null,"abstract":"We aimed to evaluate the long-term durability and valve function of handmade expanded polytetrafluoroethylene (ePTFE) valved conduits of different calibers and compare their outcomes with those of bioprosthetic pulmonary valve replacement (PVR). We retrospectively reviewed 100 patients undergoing RVOT reconstruction between 2007 and 2025: 66 with ePTFE conduits and 34 with bioprosthetic valves. Patients were categorized into small-conduit, large-conduit, and PVR groups. Propensity score matching was performed to adjust for baseline differences. Mean age was 1.6 ± 1.8, 11.2 ± 6.5, and 26.3 ± 16.9 years in the small-conduit, large-conduit, and PVR groups, respectively (p < 0.0001). Ten-year survival was similar among groups (100%, 100%, and 97%; p = 0.19). In contrast, the small-conduit group showed significantly lower freedom from RVOT reoperation than the large-conduit and PVR groups (53%, 85%, and 93%; p < 0.001), driven by progressive pulmonary stenosis (10-year freedom from moderate pulmonary stenosis: 9%, 55%, and 58%; p = 0.01). Freedom from moderate pulmonary regurgitation remained comparable (80%, 94%, and 85%; p = 0.37). In the matched cohort, conduit and PVR groups demonstrated similar freedom from reoperation (94% vs. 89%; p = 0.34), with numerically better valve function in the conduit group. In conclusion, large-caliber handmade ePTFE valved conduits demonstrated favorable long-term durability, with outcomes comparable to PVR in adolescent- and adult-sized patients. They may be a reasonable option for selected younger patients requiring redo RVOT reconstruction.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149288210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aorto-Pulmonary Shunt Creation in Congenital Heart Disease: Different Indications, Various Modifications, but Common Technical Challenges. 先天性心脏病主动脉-肺分流术的建立：不同的适应症，各种修改，但共同的技术挑战。

IF 1.3 4区医学

Pediatric Cardiology Pub Date : 2026-10-23 DOI: 10.1007/s00246-026-04504-9

Matija Bakoš, Stanimir Georgiev, Kerstin Wustman, Paul Phillip Heinisch, Kristina Borgmann, Dunja Renner, Andreas Eicken, Julia Lemmer, Peter Ewert, Katarzyna Gendera

{"title":"Aorto-Pulmonary Shunt Creation in Congenital Heart Disease: Different Indications, Various Modifications, but Common Technical Challenges.","authors":"Matija Bakoš, Stanimir Georgiev, Kerstin Wustman, Paul Phillip Heinisch, Kristina Borgmann, Dunja Renner, Andreas Eicken, Julia Lemmer, Peter Ewert, Katarzyna Gendera","doi":"10.1007/s00246-026-04504-9","DOIUrl":"https://doi.org/10.1007/s00246-026-04504-9","url":null,"abstract":"Percutaneous creation of an aorto-pulmonary (AP) shunt has been explored in preclinical models for over 15 years, yet its clinical application remains limited. Surgical AP shunts are widely used to augment pulmonary blood flow in cyanotic congenital heart disease, but repeated thoracic operations and general anesthesia carry substantial risks in critically ill or surgically complex patients. A less invasive transcatheter alternative could therefore represent a transformative option. We report a case series of two pediatric patients in whom a percutaneous connection between the aorta and pulmonary artery was successfully established. Indications were severe cyanosis due to compromised pulmonary blood flow in one child and suprasystemic pulmonary arterial hypertension requiring decompression in the other. The procedures were technically feasible and resulted in the intended immediate hemodynamic effects, either by enhancing pulmonary perfusion or by enabling right-to-left shunting for right heart decompression. Conceptually, percutaneous AP shunt creation parallels the transcatheter Potts shunt, which is increasingly recognized as a therapeutic option in pulmonary arterial hypertension. Both approaches establish controlled communication between the aorta and pulmonary artery, adapted to distinct physiological settings. Our report represents, to our knowledge, the first description of percutaneous AP shunt creation to improve pulmonary blood flow and oxygenation in congenital heart disease, as well as the first percutaneous connection between the ascending aorta and the pulmonary artery. These cases illustrate the technical feasibility of catheter-based AP shunt creation in selected pediatric patients and support further evaluation of this approach.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149245780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal Anxiety Surrounding Fetal Cardiac Evaluation: A Prospective Single-Center Cohort Study. 母亲对胎儿心脏评估的焦虑：一项前瞻性单中心队列研究。

IF 1.3 4区医学

Pediatric Cardiology Pub Date : 2026-10-23 DOI: 10.1007/s00246-026-04522-7

Soujanya Bogarapu, Tyler Legro, David W Jantzen, Jitendra J Shah, Cecilia A Albaro

{"title":"Maternal Anxiety Surrounding Fetal Cardiac Evaluation: A Prospective Single-Center Cohort Study.","authors":"Soujanya Bogarapu, Tyler Legro, David W Jantzen, Jitendra J Shah, Cecilia A Albaro","doi":"10.1007/s00246-026-04522-7","DOIUrl":"https://doi.org/10.1007/s00246-026-04522-7","url":null,"abstract":"Fetal echocardiography has transformed prenatal cardiac diagnosis, yet the emotional burden of referral and evaluation remains poorly characterized. We aimed to quantify maternal anxiety before and after fetal cardiac evaluation (FCE), identify clinical predictors of anxiety, and assess whether anxiety changes following evaluation and consultation regardless of outcome. In this prospective cohort study, 117 pregnant women undergoing initial or follow-up FCE completed pre- and post-consultation assessments using a seven-item symptom inventory adapted from the Stanford Acute Stress Reaction Questionnaire (SASRQ; score range 7-42). Participants were classified as anxious or non-anxious by direct self-report. Scores were compared with paired t-tests; exploratory multivariable models adjusted for clinical, demographic, and referral covariates, including prior pregnancy loss, psychiatric history, and diagnostic outcome. 80% of participants (94/117) reported anxiety about the FCE before evaluation; prior pregnancy loss was associated with anxious state (p = 0.049). Following FCE and consultation, mean symptom scores in the anxious group fell from 15.07 to 9.03, a 6.04-point (40.1%) reduction (p < 0.001), with reductions across symptom domains regardless of diagnostic outcome. Scores in the non-anxious group did not change significantly (8.48 to 7.87; p = 0.27). Most women referred for FCE report anxiety before evaluation. FCE with consultation was associated with a substantial reduction in anxiety symptoms in these women, irrespective of whether a cardiac abnormality was found. Although the uncontrolled pre-post design cannot establish causation, these findings suggest that diagnostic clarity and expert consultation may themselves be anxiety-reducing and support evaluation of integrated psychosocial care models in fetal cardiology.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149245841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0