Pediatric Cardiology最新文献_第4页

Endocrine Effects of Arginine-Vasopressin After Pediatric Cardiac Surgery. 精氨酸-加压素对小儿心脏手术后内分泌的影响。

IF 1.4 4区医学

Pediatric Cardiology Pub Date : 2025-10-01 DOI: 10.1007/s00246-025-04049-3

Ilias Iliopoulos, Saul Flores, Matthew Coghill, Wonshill Koh, Jeffrey A Alten, David S Cooper, Jang Dong Seo, Rohit Loomba

{"title":"Endocrine Effects of Arginine-Vasopressin After Pediatric Cardiac Surgery.","authors":"Ilias Iliopoulos, Saul Flores, Matthew Coghill, Wonshill Koh, Jeffrey A Alten, David S Cooper, Jang Dong Seo, Rohit Loomba","doi":"10.1007/s00246-025-04049-3","DOIUrl":"https://doi.org/10.1007/s00246-025-04049-3","url":null,"abstract":"Arginine-vasopressin (AVP) stimulates adrenocorticotropic hormone (ACTH) secretion and may contribute to the stress response after surgery. Its endocrine effects in children undergoing congenital heart surgery remain unclear. We prospectively evaluated 49 children (median age 8 months, IQR 5-59 months; median weight 11.0 kg, IQR 7.2-26.3 kg) after corrective cardiac surgery with cardiopulmonary bypass. Patients receiving AVP within 48 h postoperatively (n = 23) were compared with those not treated (n = 26). Baseline hormone levels (AVP, ACTH, cortisol, cortisol-binding globulin) were measured. Serial cortisol, ACTH, sodium, and glucose levels were analyzed. Time-series linear regression models examined associations between AVP therapy and adjusting for covariates such as cortisol, ACTH, CBG, and AVP levels. Baseline did not differ between groups. AVP therapy was not associated with significant differences in ACTH or cortisol over time. A non-significant trend toward higher cortisol was observed in AVP-treated patients. Regression analyses demonstrated significant associations between ACTH and cortisol (coefficient = 0.0325, p < 0.01), cortisol and systolic blood pressure (coefficient = 0.005, p < 0.01), and baseline AVP level with systolic blood pressure (coefficient = 0.003, p < 0.01) and renal oxygen extraction ratio (coefficient = 0.124, p = 0.01) and hormone levels. In this prospective cohort of children after congenital heart surgery, AVP therapy did not significantly alter ACTH or cortisol levels. Cortisol and baseline AVP levels were independently associated with hemodynamic markers. These findings suggest that the hemodynamic benefit of AVP is unlikely to be mediated through hypothalamic-pituitary-adrenal axis activation. Larger studies are needed to confirm these results.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145207413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Single-Center Experience with Sacubitril/Valsartan in Patients with Congenital Heart Disease. 修正：先天性心脏病患者使用苏比里尔/缬沙坦的单中心经验。

IF 1.4 4区医学

Pediatric Cardiology Pub Date : 2025-10-01 DOI: 10.1007/s00246-025-03973-8

Anusha Konduri, Ashley Duimstra, Ray Lowery, Sunkyung Yu, Ashley Huebschman, Bronwyn Crandall, Tiffany Hunter, Heang M Lim, Amanda D McCormick, Kurt R Schumacher, David M Peng

引用次数: 0

Inclusive ABO-Incompatible Listing for Pediatric Heart Transplantation Results in Comparable Post-Transplant Rejection-Free Survival in a Single-Center Series. 在一个单中心系列研究中，小儿心脏移植手术的包容性ABO不相容列表可获得相似的移植后无排斥生存率。

IF 1.4 4区医学

Pediatric Cardiology Pub Date : 2025-10-01 Epub Date: 2024-08-08 DOI: 10.1007/s00246-024-03601-x

Emily A Downs, Michal Schäfer, Melanie D Everitt, Michael Aubrey, Max Mitchell, James Jaggers, David Campbell, Matthew L Stone

{"title":"Inclusive ABO-Incompatible Listing for Pediatric Heart Transplantation Results in Comparable Post-Transplant Rejection-Free Survival in a Single-Center Series.","authors":"Emily A Downs, Michal Schäfer, Melanie D Everitt, Michael Aubrey, Max Mitchell, James Jaggers, David Campbell, Matthew L Stone","doi":"10.1007/s00246-024-03601-x","DOIUrl":"10.1007/s00246-024-03601-x","url":null,"abstract":"ABO-incompatible (ABOi) heart transplantation (HT) has increased organ availability for infants with end-stage heart failure. Despite increasing adoption of ABOi listing for HT, data remain limited regarding pre- and post-HT immunologic profiles to guide listing practices and post-HT follow-up. Thus, the purpose of this study was to evaluate post-HT outcomes at a single center employing inclusive ABOi listing irrespective of pre-HT isohemagglutinin titers. All HT recipients listed at less than 24 months of age at our institution from 2010-2020 were included. Pre- and post-operative variables were compared for ABOi and ABO-compatible (ABOc) recipients. Separate iso-IgG and iso-IgM titers were monitored pre- and post-HT. Primary outcomes were compared between ABOi versus ABOc groups at mid-term follow-up. 51 HTs were performed on 50 patients from 2010-2020 (ABOi, N = 13; ABOc, N = 38). Six ABOi recipients received intra-operative plasma exchange for elevated titers (greater than 1:8 for IgG or IgM or reverse type greater than 2 +). Treated rejection, DSA, CAV, primary graft failure, need for re-HT, and survival were comparable between ABOi and ABOc groups at mid-term follow-up. An inclusive approach to ABOi HT listing for infants less than 24 months of age results in comparable post-transplant rejection-free survival, CAV, and prevalence of DSA at mid-term follow-up. These data define a potential role for specific IgM and IgG testing to promote understanding of risk stratification in pediatric ABOi listing, and support an inclusive strategy irrespective of high pre-HT titers to expand the number of available donor hearts for infants and older children awaiting HT.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":"1925-1931"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141902581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fetal Right Heart Strain in Systemic Right Ventricles and Impact on Post-surgical Outcomes. 系统性右心室胎儿右心应变及其对手术后结果的影响

IF 1.4 4区医学

Pediatric Cardiology Pub Date : 2025-10-01 Epub Date: 2024-08-09 DOI: 10.1007/s00246-024-03607-5

Dana M DeCarlo, Christine Cha, Kristyn Pierce, Rakesh K Singh, Ranjini Srinivasan

{"title":"Fetal Right Heart Strain in Systemic Right Ventricles and Impact on Post-surgical Outcomes.","authors":"Dana M DeCarlo, Christine Cha, Kristyn Pierce, Rakesh K Singh, Ranjini Srinivasan","doi":"10.1007/s00246-024-03607-5","DOIUrl":"10.1007/s00246-024-03607-5","url":null,"abstract":"Patients with hypoplastic left heart syndrome (HLHS) and its variants rely on the right ventricle (RV) to provide cardiac output. Diminished RV systolic function has been associated with poor clinical outcomes in this population. Echocardiographic strain has emerged as a useful method to quantify RV deformation. We aimed to describe fetal strain in the systemic RV and further investigate if there was any correlation with clinical outcomes. We conducted a retrospective, single center study evaluating strain in fetuses with systemic RV. We measured fetal RV global longitudinal strain (GLS) and segmental strain using Tomtec 2D speckle tracking software and compared these findings to controls. Fifty patients with systemic RV were included in the study group with controls matched one to one for each echocardiogram. Ten patients died after first-stage palliation. GLS was reproducible, with interobserver ICC 0.82. There was no statistically significant difference in GLS among different HLHS subtypes. Abnormal GLS did not correlate with worse clinical outcomes. GLS in systemic RVs in the 2nd and 3rd trimester did not vary significantly throughout gestation and did not correlate with clinical outcomes. Risk factors associated with poor outcome were mainly postnatal. Multi-centered studies are needed to determine if these findings hold true in a larger sample size.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":"2060-2069"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141913646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Update of How Pediatric Cardiologists Noninvasively Evaluate Patients with Hypoplastic Left Heart Syndrome: 2013 vs. 2023. 小儿心脏病专家如何对左心发育不全综合征患者进行无创评估的最新进展：2013 年与 2023 年。

IF 1.4 4区医学

Pediatric Cardiology Pub Date : 2025-10-01 Epub Date: 2024-08-06 DOI: 10.1007/s00246-024-03605-7

Angela C Onorato, Craig Fleishman, Holly Nadorlik, David Brown, Chance Alvarado, Sara Conroy, Corey Stiver, Clifford L Cua

{"title":"Update of How Pediatric Cardiologists Noninvasively Evaluate Patients with Hypoplastic Left Heart Syndrome: 2013 vs. 2023.","authors":"Angela C Onorato, Craig Fleishman, Holly Nadorlik, David Brown, Chance Alvarado, Sara Conroy, Corey Stiver, Clifford L Cua","doi":"10.1007/s00246-024-03605-7","DOIUrl":"10.1007/s00246-024-03605-7","url":null,"abstract":"Noninvasive functional assessment of systemic right ventricles (RV) in hypoplastic left heart syndrome (HLHS) is challenging. This study aimed to compare pediatric cardiologists' current noninvasive imaging practices to those reported in 2013. A web-based survey was distributed to pediatric cardiologists via various listservs which queried timing of echocardiograms during HLHS palliative stages and measurements of RV function. Demographics of 156 participants who completed the 2023 survey were similar to survey participants in 2013 (n = 222). Respondents were mostly male (62%), echocardiographers (48%), in university-based practice (67%) in North America (95%). Echocardiograms were predominantly obtained monthly during interstage I (41%), every 6 months during interstage II (56%), and every year post-Fontan (68%), which is consistent from 2013. Routine cardiac magnetic resonance imaging (cMRI) significantly increased in interstage II (8.2%, 17%) and post-Fontan (24%, 56%) populations, respectively. Qualitative assessment (41%), ejection fraction (EF) by 3D (20%), fractional area change (16%), and RV strain/strain rate (13%) were preferred methods for systolic assessment, whereas a plurality of respondents (41%) did not believe RV diastolic measurements were valid. The largest gap between currently obtained and desired measurements existed for EF by 3D (46.5% points) and RV strain/strain rate (44.5% points). No differences existed between imagers compared to non-imagers. Variability in evaluating HLHS patients continues among pediatric cardiologists compared to 10 years ago. Qualitative assessment remains the primary RV systolic functional evaluation. Providers do not rely on quantitative RV diastolic function assessments in HLHS patients. Use of cMRI is increasing for RV functional analysis.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":"2004-2012"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the Editor: "Comparison of Risk Scoring Systems in Predicting Kawasaki Disease Associated Coronary Artery Dilation in a North American Cohort". 致编辑的信：“在北美队列中预测川崎病相关冠状动脉扩张风险评分系统的比较”。

IF 1.4 4区医学

Pediatric Cardiology Pub Date : 2025-10-01 Epub Date: 2024-12-24 DOI: 10.1007/s00246-024-03754-9

F N U Ridham, Insiya Fatima Azad, Muskan Kumari, Kanwal Majeed

引用次数: 0

Comparison of Risk-Scoring Systems in Predicting Kawasaki Disease Associated Coronary Artery Dilation in a North American Cohort. 在北美队列中预测川崎病相关冠状动脉扩张的风险评分系统比较。

IF 1.4 4区医学

Pediatric Cardiology Pub Date : 2025-10-01 Epub Date: 2024-08-04 DOI: 10.1007/s00246-024-03611-9

Elridge Schwartzenburg, Jacob Strelow, Shahryar M Chowdhury

{"title":"Comparison of Risk-Scoring Systems in Predicting Kawasaki Disease Associated Coronary Artery Dilation in a North American Cohort.","authors":"Elridge Schwartzenburg, Jacob Strelow, Shahryar M Chowdhury","doi":"10.1007/s00246-024-03611-9","DOIUrl":"10.1007/s00246-024-03611-9","url":null,"abstract":"Scoring systems used to predict morbidity in children with Kawasaki disease (KD) have been developed and validated in Asian populations. The objective of this study was to assess their utility in predicting the development of coronary artery dilation in children with KD in North America. This was a secondary analysis of a National Institutes of Health / National Heart, Lung, and Blood Institute (NIH/NHLBI) Pediatric Heart Network public use dataset from a multicenter, randomized controlled trial of pulse steroid therapy in KD in a North American cohort. The primary outcome of interest was development of coronary artery dilation. The Harada, Kobayashi, Egami, and Sano scoring systems, originally developed to predict risk of intravenous immunoglobulin (IVIG) resistance in Kawasaki patients in Japan, were applied to this cohort. Subjects were kept in the analysis only if there were complete data for every element of each scoring system-Harada (n = 132), Kobayashi (n = 88), Egami (n = 139), and Sano (n = 82). Patients classified as high-risk by the Harada score were more likely to have significant coronary artery dilation (p = 0.042), were more likely to require IVIG retreatment (p = 0.002), and were more likely to require hospital readmission (p < 0.001). The Egami, Kobayashi, and Sano scores were not predictive for any measured outcome. The Harada score can be useful in identifying KD patients at risk for developing coronary artery dilation and IVIG resistance. The Harada score has demonstrated higher sensitivity but lower specificity, making it a valuable screening tool that may benefit from supplementary diagnostic methods.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":"2013-2018"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11790979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141889889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety and Efficacy of GLP-1 Agonists in a Cohort of Patients with Fontan Circulation. GLP-1 激动剂在一组丰坦循环患者中的安全性和有效性。

IF 1.4 4区医学

Pediatric Cardiology Pub Date : 2025-10-01 Epub Date: 2024-11-12 DOI: 10.1007/s00246-024-03700-9

Andrew M Freddo, Humera Ahmed, Jonathan B Edelson, Juan M Ortega-Legaspi, Sumeet Vaikunth

{"title":"Safety and Efficacy of GLP-1 Agonists in a Cohort of Patients with Fontan Circulation.","authors":"Andrew M Freddo, Humera Ahmed, Jonathan B Edelson, Juan M Ortega-Legaspi, Sumeet Vaikunth","doi":"10.1007/s00246-024-03700-9","DOIUrl":"10.1007/s00246-024-03700-9","url":null,"abstract":"There are a growing number of adult patients palliated to a Fontan circulation. As these patients age, many develop symptomatic heart failure (d'Udekem et al in Circulation 130:S32-S38, 2014) that is exacerbated by acquired comorbidities such as obesity and hypertension. Increased body mass index (BMI) and adiposity have been associated with worse hemodynamics and clinical outcomes in these patients (Yogeswaran et al in J Am Hear Assoc: Cardiovasc Cerebrovasc Dis 12:e026732, 2023). Recently, glucagon-like peptide-1 (GLP-1) agonists, originally developed to treat diabetes mellitus, received FDA approval for weight loss and have been shown to reduce the risk of cardiovascular events in the general population (Vilsbøll et al in BMJ 344:d7771, 2012). There are limited data on these medications in patients with a Fontan circulation. We conducted a retrospective review of adults with Fontan circulation followed in our adult congenital heart disease (ACHD) clinic between 2009 and 2023 and identified 8 patients prescribed GLP-1 agonists. We found that GLP-1 agonists were well-tolerated and led to modest reduction in weight and blood pressure. Further study of the use of these medications in this population is warranted.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":"2137-2139"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Fetal Echocardiography in Predicting Postnatal Pulmonary Venous Obstruction in Neonates with TAPVR: A Single Center Experience. 胎儿超声心动图在预测TAPVR新生儿出生后肺静脉阻塞中的作用：单中心经验。

IF 1.4 4区医学

Pediatric Cardiology Pub Date : 2025-10-01 Epub Date: 2025-01-22 DOI: 10.1007/s00246-025-03774-z

Manal Alqahtani, Drishti Tolani, Mirela Dugulescu, Jenna Keelan

{"title":"The Role of Fetal Echocardiography in Predicting Postnatal Pulmonary Venous Obstruction in Neonates with TAPVR: A Single Center Experience.","authors":"Manal Alqahtani, Drishti Tolani, Mirela Dugulescu, Jenna Keelan","doi":"10.1007/s00246-025-03774-z","DOIUrl":"10.1007/s00246-025-03774-z","url":null,"abstract":"Total anomalous pulmonary venous return (TAPVR) is a high risk and rare cardiac malformation with a low prenatal detection rate and predicting obstruction in these cases is difficult. We sought to investigate fetal echocardiographic parameters associated with postnatal pulmonary venous obstruction (PPVO). We performed a retrospective review of 26 patients with TAPVR who had a fetal echocardiogram from 2010 to 2021. Blinded readers analyzed the fetal Doppler features of the pulmonary veins (PV) and vertical veins (VV) at final fetal assessment. Of the 26 patients, 17 (65%) were prenatally diagnosed and overall 10 (38.5%) developed PPVO. All patients had additional associated congenital heart disease. Compared to patients without PPVO, patients with PPVO had a lower VV variability index (VI) (0.51 (0.17-0.79) vs 1.43 (0.54-2.58); p = 0.003), a higher likelihood of having an abnormal VV or PV Doppler pattern (p = 0.042, p = 0.015), a higher VV minimum velocity (0.435 m/s (0.17-1.05) vs 0.14 m/s (- 0.16 to 0.35) p = 0.001) and a higher VV mean velocity (0.641 m/s (0.31-1.15) vs 0.321 m/s (0.19-0.5); p = 0.009). A fetal VV VI of ≤ 0.8 was associated with PPVO (100% sensitivity, 86% specificity). Our data show that some fetal PV and VV Doppler indices are significantly different between those that develop PPVO and those who do not, with the most significant difference seen in the VV variability index and VV minimum velocity. Prenatal predictors of PPVO have the potential to influence prenatal counseling, perinatal care, surgical timing, and outcomes associated with this critical diagnosis.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":"1941-1950"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-Traumatic Stress in Mothers of Children Having Complex Cardiac Surgery Early in Life. 早期接受复杂心脏手术儿童的母亲的创伤后应激反应。

IF 1.4 4区医学

Pediatric Cardiology Pub Date : 2025-10-01 Epub Date: 2024-12-16 DOI: 10.1007/s00246-024-03734-z

Gwen Y Bond, Charlene M T Robertson, Helen Knorren, Erica Rodriques de Miranda Queiroz, M Florencia Ricci, Gonzalo Garcia Guerra, Winnifred Savard, Ariba Kamal, Irina A Dinu, Ari R Joffe

{"title":"Post-Traumatic Stress in Mothers of Children Having Complex Cardiac Surgery Early in Life.","authors":"Gwen Y Bond, Charlene M T Robertson, Helen Knorren, Erica Rodriques de Miranda Queiroz, M Florencia Ricci, Gonzalo Garcia Guerra, Winnifred Savard, Ariba Kamal, Irina A Dinu, Ari R Joffe","doi":"10.1007/s00246-024-03734-z","DOIUrl":"10.1007/s00246-024-03734-z","url":null,"abstract":"To determine: (i) frequency of probable post-traumatic stress disorder (PTSD) in mothers of infants after complex cardiac surgery (CCS), (ii) predictors of probable PTSD, and (iii) impact on child neurodevelopment. The Impact of Event Scale-Revised (IES-R) was administered to 60 mothers of infants ≥ 6 months after CCS at ≤ 6 weeks of age. The IES-R measures response to a specific traumatic event: Scores < 24, no concern; 24-32, clinical concern; and ≥ 33, probable diagnosis of PTSD. Post-survey childhood outcomes obtained at 21-months used Bayley Scales of Infant and Toddler Development-Third Edition. Multiple logistic and linear regressions were used to predict high IES-R scores from peri-operative and demographic variables and determine association between maternal IES-R scores and outcomes, reported as Odds Ratio (OR) and Effect Size (ES) with 95% Confidence Intervals (95% CI). IES-R scores ≥ 33 occurred in 14/60 (23%) of mothers. Significant risk factors for IES-R ≥ 33 were days of ventilation after first surgery, OR 1.149 (95% CI 1.037, 1.273), p = 0.008, and birth weight z-scores, OR 0.352 (0.140, 0.881), p = 0.026. Bayley cognitive, language, and motor scores were significantly lower for children whose mothers had IES-R ≥ 33. The IES-R was independently associated with cognitive, ES -0 .23 (95%CI -0 0.39, -0 0.08), p = 0.036 and language, ES -0 0.17 (95%CI -0 0.33, -0 0.06), p = 0.043 scores. Probable PTSD occurred in 23% of mothers ≥ 6 month after discharge of their infant following CCS. Toddlers of mothers with probable PTSD had lower cognitive and language scores suggesting a relation between PTSD and development requiring further study.","PeriodicalId":19814,"journal":{"name":"Pediatric Cardiology","volume":" ","pages":"1823-1832"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0