Pharmaceutisch weekblad. Scientific edition最新文献_第7页

Continuation and maintenance therapy with antidepressive agents. Meta-analysis of research (II) 抗抑郁药物的继续和维持治疗。研究荟萃分析(二)

Pharmaceutisch weekblad. Scientific edition Pub Date : 1992-04-24 DOI: 10.1007/BF01980485

J M Keppel Hesselink

引用次数: 2

Pharmaceutisch weekblad. Scientific edition Pub Date : 1992-04-24 DOI: 10.1007/BF01980484

P C Pasker-De Jong, T K Eskes, P W Van Dongen, K L Bos

引用次数: 3

Stability of total parenteral nutrition supplied as 'all-in-one' for children with chemotherapy-linked hyperhydration. 化疗相关性水合过度儿童全肠外营养“一体化”的稳定性

Pharmaceutisch weekblad. Scientific edition Pub Date : 1992-04-24 DOI: 10.1007/BF01980482

M J Korrenhof, J G Timmer

{"title":"Stability of total parenteral nutrition supplied as 'all-in-one' for children with chemotherapy-linked hyperhydration.","authors":"M J Korrenhof, J G Timmer","doi":"10.1007/BF01980482","DOIUrl":"https://doi.org/10.1007/BF01980482","url":null,"abstract":"The maximal allowable concentrations of calcium and phosphate in total parenteral nutrition mixtures for children from one compartment were investigated. Children treated with both chemotherapy and total parenteral nutrition are supplied with high amounts of electrolytes (besides normal nutritive needs) in a restricted volume. Such nutritive mixtures are suspected of precipitation and disintegration of the lipid emulsion by (polyvalent) electrolytes, such as calcium and phosphate. Calcium (range 1.5-150 mmol/l total parenteral nutrition) and phosphate (range 21-300 mmol/l) were added to a test total parenteral nutrition mixture. After storage (24 and 48 h) at both 22 degrees C and 37 degrees C the mixtures were observed by microscopy for the presence of precipitates. The stability of the fat emulsion was visually assessed and the particle size distribution was measured by flow cytometry. The examined total parenteral nutrition mixtures (pH 5.4-5.7) were stable during 48 h at 37 degrees C if the calcium concentration is below 16 mmol/l, the phosphate concentration is below 52 mmol/l and the product of both concentrations is below 250 mmol2/l2.","PeriodicalId":19804,"journal":{"name":"Pharmaceutisch weekblad. Scientific edition","volume":"14 2","pages":"50-4"},"PeriodicalIF":0.0,"publicationDate":"1992-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01980482","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12697896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Is Recormon less painful than Eprex after subcutaneous administration? 雷蒙皮下给药后疼痛是否比依普雷克斯轻?

Pharmaceutisch weekblad. Scientific edition Pub Date : 1992-04-24 DOI: 10.1007/BF01980483

M W Hendriks, F P Peters, P M Hooymans, T W Van de Wiel, D Janknegt, R Janknegt, J J Lohman

{"title":"Is Recormon less painful than Eprex after subcutaneous administration?","authors":"M W Hendriks, F P Peters, P M Hooymans, T W Van de Wiel, D Janknegt, R Janknegt, J J Lohman","doi":"10.1007/BF01980483","DOIUrl":"https://doi.org/10.1007/BF01980483","url":null,"abstract":"In this study, we examined the differences in pain score after subcutaneous injection of the epoetin preparations Eprex and Recormon. Patients (n = 30) received 5 injections Eprex and 5 injections Recormon in a randomized double-blind sequence. 10 Min after receiving the injection the patient was asked to complete a visual and a verbal analogue scale and two descriptive scales. The results of 25 patients were used for statistical evaluation. The overall results indicate that there are significantly more patients reporting pain after subcutaneous injection of Eprex than after Recormon (11 versus 2 patients, p less than 0.05; McNemar test). 12 Patients reported no differences in pain. 43 Out of 123 injections Eprex and 69 out of 125 injections Recormon caused no pain (p less than 0.01; chi 2 9.455). For 4 patients Recormon was significantly (p less than 0.05) less painful than Eprex. It can be concluded that Recormon may be a less painful alternative for individual patients reporting pain after subcutaneous injection of Eprex.","PeriodicalId":19804,"journal":{"name":"Pharmaceutisch weekblad. Scientific edition","volume":"14 2","pages":"55-8"},"PeriodicalIF":0.0,"publicationDate":"1992-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01980483","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12697812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Handling of risk-bearing drugs during pregnancy. Do we choose less risky alternatives? 孕期高危药物的处理。我们会选择风险较小的选择吗?

Pharmaceutisch weekblad. Scientific edition Pub Date : 1992-04-24 DOI: 10.1007/BF01980480

L T De Jong-Van den Berg, P B Van den Berg, F M Haaijer-Ruskamp, M N Dukes, H Wesseling

{"title":"Handling of risk-bearing drugs during pregnancy. Do we choose less risky alternatives?","authors":"L T De Jong-Van den Berg, P B Van den Berg, F M Haaijer-Ruskamp, M N Dukes, H Wesseling","doi":"10.1007/BF01980480","DOIUrl":"https://doi.org/10.1007/BF01980480","url":null,"abstract":"The drug use of nearly 2,000 pregnant women was evaluated at the level of the individual patient for the drugs belonging to the Australian risk categories B3, C and D. The pattern of changes in the use of these drugs is studied in terms of women who discontinue (d), continue (c) or begin (b) using the drug during pregnancy. The ratios d/(c+b) and d/b were the highest for the drugs belonging to the high-risk groups and the lowest for drugs from the low-risk categories. This suggests a congruence between theoretical knowledge and daily practice. Patients who had already been using a drug for a long time before pregnancy, more frequently continued using that drug than patients who had been using the drug only incidentally before. The described daily dose for the riskful drugs was approximately 20% lower in patients who started to use a drug during pregnancy compared to those who continued drug use. The data from this analysis indicate that the prescribing physician is generally aware of the possible risks of drug use during pregnancy. The d/(b+c) and d/b ratios are shown to be a good measure of prescribing behaviour in relation to pregnancy and can be used to compare knowledge of theory and daily practice.","PeriodicalId":19804,"journal":{"name":"Pharmaceutisch weekblad. Scientific edition","volume":"14 2","pages":"38-45"},"PeriodicalIF":0.0,"publicationDate":"1992-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01980480","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12697894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Liquid chromatographic estimation of tranylcypromine in human plasma. 人血浆中丙基环丙胺的液相色谱测定。

Pharmaceutisch weekblad. Scientific edition Pub Date : 1992-04-24 DOI: 10.1007/BF01980481

P G Krugers Dagneaux, C P Loohuis, J T Klein Elhorst, T S Van der Veer

引用次数: 0

Therapeutic decision making of physicians. 医生的治疗决策。

Pharmaceutisch weekblad. Scientific edition Pub Date : 1992-02-21 DOI: 10.1007/BF01989219

P Denig, F M Haaijer-Ruskamp

引用次数: 43

Enzyme inhibition in Cardiovascular disease, Weesp, The Netherlands, 13 December 1991. Abstracts. 心血管疾病中的酶抑制，Weesp，荷兰，1991年12月13日。摘要。

Pharmaceutisch weekblad. Scientific edition Pub Date : 1992-02-21

引用次数: 0

Pharmacokinetics of amoxycillin in elderly in-patients. 老年住院患者阿莫西林的药代动力学。

Pharmaceutisch weekblad. Scientific edition Pub Date : 1992-02-21 DOI: 10.1007/BF01989222

R Janknegt, J Boogaard-Van den Born, B A Hameleers, P M Hooymans, J Rang, C A Smits, M E Willems-Thissen

引用次数: 10

Drug use in non-hospitalized children. 非住院儿童的药物使用情况

Pharmaceutisch weekblad. Scientific edition Pub Date : 1992-02-21 DOI: 10.1007/BF01989218

E J Sanz

引用次数: 2