PeerJ最新文献

{"title":"Meta-analysis of the efficacy of the erector spinae plane block after spinal fusion surgery.","authors":"Yi He, Heng Liu, Peng Ma, Jing Zhang, Qiulian He","doi":"10.7717/peerj.18332","DOIUrl":"10.7717/peerj.18332","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the efficacy of erector spinal plane block (ESPB) after spinal fusion surgery in this study.</p><p><strong>Methods: </strong>The PubMed, Embase, Cochrane library, and Web of Science databases were searched with a search deadline of March 30, 2024, and Stata 15.0 was used to analyze the data from the included studies.</p><p><strong>Result: </strong>Nine randomized controlled trials involving 663 patients were included. Meta-analysis showed that EPSB could reduce pain scores at 2h (standard mean difference (SMD) = -0.78, 95% CI [-1.38 to -0.19], GRADE: Moderate), 6 h (SMD = -0.81, 95% CI [-1.23 to -0.38], GRADE: Moderate), 12 h (SMD = -0.59, 95% CI [-1.05 to -0.13], GRADE: Moderate), 24 h (SMD = -0.54, 95% CI [-0.86 to -0.21], GRADE: Moderate), 48 h (SMD = -0.40, 95% CI [-0.75 to -0.05], GRADE: Moderate) after spinal fusion surgery, as well as the PCA (analgesia medication use) (SMD = -1.67, 95% CI [-2.67 to -0.67], GRADE: Moderate). However, EPSB had no effect on intraoperative blood loss (SMD = -0.28, 95% CI [-1.03 to 0.47], GRADE: Low) and length of hospital stay (SMD = -0.27, 95% CI [-0.60-0.06], GRADE: Low).</p><p><strong>Conclusion: </strong>Combined with the current findings, EPSB may reduce pain scores in spinal fusion surgery, possibly reducing the use of postoperative analgesics. However, due to the limitations of the study, we need more high-quality, multi-center, large sample randomized controlled trials to merge.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of microbiomes in cooperative detoxification mechanisms of arsenate reduction and arsenic methylation in surface agricultural soil.","authors":"Nattanan Rueangmongkolrat, Pichahpuk Uthaipaisanwong, Kanthida Kusonmano, Sasipa Pruksangkul, Prinpida Sonthiphand","doi":"10.7717/peerj.18383","DOIUrl":"10.7717/peerj.18383","url":null,"abstract":"<p><p>Microbial arsenic (As) transformations play a vital role in both driving the global arsenic biogeochemical cycle and determining the mobility and toxicity of arsenic in soils. Due to the complexity of soils, variations in soil characteristics, and the presence and condition of overlying vegetation, soil microbiomes and their functional pathways vary from site to site. Consequently, key arsenic-transforming mechanisms in soil are not well characterized. This study utilized a combination of high-throughput amplicon sequencing and shotgun metagenomics to identify arsenic-transforming pathways in surface agricultural soils. The temporal and successional variations of the soil microbiome and arsenic-transforming bacteria in agricultural soils were examined during tropical monsoonal dry and wet seasons, with a six-month interval. Soil microbiomes of both dry and wet seasons were relatively consistent, particularly the relative abundance of <i>Chloroflexi</i>, <i>Gemmatimonadota</i>, and <i>Bacteroidota</i>. Common bacterial taxa present at high abundance, and potentially capable of arsenic transformations, were <i>Bacillus</i>, <i>Streptomyces</i>, and <i>Microvirga</i>. The resulting shotgun metagenome indicated that among the four key arsenic-functional genes, the <i>arsC</i> gene exhibited the highest relative abundance, followed by the <i>arsM</i>, <i>aioA</i>, and <i>arrA</i> genes, in declining sequence. Gene sequencing data based on 16S rRNA predicted only the <i>arsC</i> and <i>aioA</i> genes. Overall, this study proposed that a cooperative mechanism involving detoxification through arsenate reduction and arsenic methylation was a key arsenic transformation in surface agricultural soils with low arsenic concentration (7.60 to 10.28 mg/kg). This study significantly advances our knowledge of arsenic-transforming mechanisms interconnected with microbial communities in agricultural soil, enhancing pollution control measures, mitigating risks, and promoting sustainable soil management practices.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of fermentation conditions for physcion production of <i>Aspergillus chevalieri</i> BYST01 by response surface methodology.","authors":"Shuxiang Zhang, Zhou Jiang, Suwen An, Xiaolan Jiang, Yinglao Zhang","doi":"10.7717/peerj.18380","DOIUrl":"10.7717/peerj.18380","url":null,"abstract":"<p><p>This study aimed to optimize the culture conditions of the termite-derived fungus <i>Aspergillus chevalieri</i> BYST01 for the production of physcion, a characteristic component of the traditional herb rhubarb, which has been commercially approved as a botanical fungicide in China. First, potato dextrose broth was screened as the suitable basal medium for further optimization, with an initial yield of 28.0 mg/L. Then, the suitable carbon source, fermentation time, temperature, pH value, and the rotary shaker speed for physcion production were determined using the one-variable-at-a-time method. Based on the results of single factors experiments, the variables with statistically significant effects on physcion production were further confirmed using the Plackett-Burman design (PBD). Among the five variables, temperature, initial pH, and rotary shaker speed were identified as significant factors (<i>P</i> < 0.05) for physcion productivity in the PDB and were further analyzed by response surface methodology (RSM). Finally, we found that the maximum physcion production (82.0 mg/L) was achieved under the following optimized conditions:initial pH 6.6, rotary shaker speed of 177 rpm, temperature of 28 °C, and glucose concentration of 30 g/L in PDB medium after 11 d of fermentation. The yield of physcion under the optimized culture conditions was approximately threefold higher than that obtained using the basal culture medium. Furthermore, the optimum fermentation conditions in the 5-L bioreactor achieved a maximal physcion yield of 85.2 mg/L within 8 d of fermentation. Hence, response surface methodology proved to be a powerful tool for optimizing physcion production by <i>A. chevalieri</i> BYST01. This study may be helpful in promoting the application of physcion produced by <i>A. chevalieri</i> BYST01 to manage plant diseases.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability and validity of My Jump 2^® app to measure the vertical jump in visually impaired five-a-side soccer athletes.","authors":"Julio Cesar Silva, Kalinne Fernandes Silva, Vitor Bruno Torres, Maria Socorro Cirilo-Sousa, Alexandre Igor Araripe Medeiros, Jacques Eanes Esmeraldo Melo, Gilmário Ricarte Batista","doi":"10.7717/peerj.18170","DOIUrl":"10.7717/peerj.18170","url":null,"abstract":"<p><strong>Background: </strong>Although <i>My Jump 2</i> ^® consistently presented excellent values of reliability and validity when compared to force platforms (FPs) and contact mats, to date no scientific investigation assessed the validity and reliability of <i>My Jump 2</i> ^® to measure jump height in visually impaired five-a-side soccer athletes. Thus, the study aimed at analyzing the validity and reliability of the <i>My Jump 2^®</i> to measure the vertical jump of five-a-side soccer athletes.</p><p><strong>Methods: </strong>Twelve visually impaired five-a-side soccer athletes, volunteered for this study. Each player performed five countermovement jumps (CMJs) and squat jumps (SJs) on a contact platform (CP) while they were simultaneously recorded using <i>My</i> <i>Jump 2</i> ^®.</p><p><strong>Results: </strong>There was almost perfect agreement between the <i>My Jump 2^®</i> and the contact platform measurements of CMJ (intraclass correlation coefficient = 0.99; <i>p</i> < 0.001) and SJ (intraclass correlation coefficient = 0.99; <i>p</i> < 0.001), heights for athletes during the first and second measurement days. <i>Bland-Altman</i> analysis showed a bias of 0.25 ± 0.5 cm; maximum SD = 1.3; minimum SD = -0.88 for CMJ, while that <i>Bland-Altman</i> analysis showed bias 0.18 ± 0.5 cm; maximum SD = 1.3; minimum SD = -0.96, for SJ.</p><p><strong>Conclusion: </strong>We can conclude that the <i>My Jump 2^®</i> is a valid and reliable method to measure CMJ and SJ in visually impaired five-a-side soccer athletes.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic evaluation of the probiotic and pathogenic features of <i>Enterococcus faecalis</i> from human breast milk and comparison with the isolates from animal milk and clinical specimens.","authors":"Lobna Badr, Muhammad Yasir, Areej A Alkhaldy, Samah A Soliman, Magdah Ganash, Safaa A Turkistani, Asif A Jiman-Fatani, Ibrahim A Al-Zahrani, Esam I Azhar","doi":"10.7717/peerj.18392","DOIUrl":"10.7717/peerj.18392","url":null,"abstract":"<p><p><i>Enterococcus faecalis</i> is considered a probiotic, commensal lactic acid bacterium in human breast milk (HBM), but there are circulating antibiotic resistant and virulence determinants that could pose a risk in some strains. The study aimed to conduct genomic analysis of <i>E. faecalis</i> isolates recovered from HBM and animal milk and to evaluate their probiotic and pathogenic features through comparative genomics with isolates from clinical specimens (<i>e.g</i>., urine, wound, and blood). Genomic analysis of 61 isolates was performed, including <i>E. faecalis</i> isolates recovered from HBM in Saudi Arabia. Genome sequencing was conducted using the MiSeq system. The fewest antibiotic resistance genes (<i>lsaA</i>, <i>tetM</i>, <i>ermB</i>) were identified in isolates from HBM and animal milk compared to clinical isolates. Several known and unknown mutations in the <i>gyrA</i> and <i>parC</i> genes were observed in clinical isolates. However, 11 virulence genes were commonly found in more than 95% of isolates, and 13 virulence genes were consistently present in the HBM isolates. Phylogenetically, the HBM isolates from China clustered with the probiotic reference strain Symbioflor 1, but all isolates from HBM and animal milk clustered separately from the clinical reference strain V583. Subsystem functions 188 of 263 were common in all analyzed genome assemblies. Regardless of the source of isolation, genes associated with carbohydrate metabolism, fatty acid, and vitamin biosynthesis were commonly found in <i>E. faecalis</i> isolates. In conclusion, comparative genomic analysis can help distinguish the probiotic or pathogenic potential of <i>E. faecalis</i> based on genomic features.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Cordyceps cateniannulata</i>, a new potential strain for controlling <i>Allantus luctifer</i> from China.","authors":"Xiaona Zhang, Yu Wu, Xue Peng, Can Liu, Guimin Yang, Qingfu Chen, Daochao Jin","doi":"10.7717/peerj.18345","DOIUrl":"10.7717/peerj.18345","url":null,"abstract":"<p><p><i>Allantus luctifer</i> is one of the most serious pests of buckwheat, with its larvae mainly damaging leaves during the seedling and flowering stages. Entomogenous fungi play a crucial role as biological regulators of arthropod populations in nature. In this paper, a newly isolated strain 19GZAl-1, was identified as <i>Cordyceps. cateniannulata</i> through the observetions of macroscopic and microscopic morphological features, and the results of rDNA- ITS sequence alignment and phylogenetic analysis. By comparing the efficacy of ten entomopathogenic fungal strains, including six strains of <i>C. cateniannulata</i> and four other <i>Cordyceps</i> species, against <i>A. luctifer</i> larvae, the new strain 19GZAl-1 exhibited the highest mortality rate. Mortality rates of <i>A. luctifer</i> larvae treated by spraying with the strain 19GZAl-1 increased as larval stage decreased, with first instar larvae showing the highest mortality rate of 85%. The appressorium from conidia invaded the larval body through areas with thin cuticle, such as larva pod base and internode folds, after which the hyphae grew rapidly, filling the haemocoel, and finally protruding from the integument upon melanization and decomposition of the intestinal wall cells. The results suggest that the strain 19GZAL-1 of <i>C. cateniannulata</i> has potential against <i>A. luctifer</i> larvae, which is significant for further study on the infection mechanism of <i>C. cateniannulata</i> on insects.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-depth study of pyroptosis-related genes and immune infiltration in colon cancer.","authors":"Bingbing Shang, Haiyan Qiao, Liang Wang, Jingyu Wang","doi":"10.7717/peerj.18374","DOIUrl":"10.7717/peerj.18374","url":null,"abstract":"<p><strong>Background: </strong>Pyroptosis is a form of regulated necrosis that occurs in many cell and tissue types and plays a critical role in tumor progression. The diagnostic value of pyroptosis-related genes (PRGs) in colon cancer has been widely investigated. In the present study, we explored the relationship between PRG expression and colon cancer.</p><p><strong>Methods: </strong>We retrieved genomic and clinical data pertaining to The Cancer Genome Atlas-Colon Adenocarcinoma from the UCSC Xena database, along with the corresponding genome annotation information from the GENCODE data portal. Utilising these data and a list of 33 pyrogenic genes, we performed principal component analysis and unsupervised clustering analysis to assess the pyroptosis subtypes. We analysed the differential expression between these subtypes to obtain PRGs, ultimately selecting 10 PRGs. We conducted Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, gene set variation analysis, protein-protein interaction, and immune infiltration analyses of these PRGs. We validated the expression of TNNC1 <i>via</i> immunohistochemistry (IHC) and real-time quantitative PCR.</p><p><strong>Results: </strong>After rigorous screening, excluding patients with incomplete survival data and unmatched transcriptomes, we refined our study cohort to 431 patients. We performed differential mRNA analysis and identified 445 PRGs, 10 of which were selected as hub genes. These genes were associated with various immune cell types. Specifically, <i>TNNC1</i> expression was positively associated with immature dendritic cells and NK CD56⁺ cells. IHC staining indicated higher TNNC1 expression levels in tumor samples. Notably, TNNC1 expression levels were high in all the colon cancer cell lines, particularly in SW480 cells.</p><p><strong>Conclusion: </strong>In this study, we explored the characteristics of PRGs in colon cancer and identified novel biological targets for early individualised treatment and accurate diagnosis of colon cancer, thus contributing to the advancement of clinical oncology.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forkhead box D subfamily genes in colorectal cancer: potential biomarkers and therapeutic targets.","authors":"Ying Chen, Haiyan Qiao, Ruiqi Zhong, Lei Sun, Bingbing Shang","doi":"10.7717/peerj.18406","DOIUrl":"10.7717/peerj.18406","url":null,"abstract":"<p><strong>Background: </strong>The forkhead box (FOX) family members regulate gene transcription and expression. FOX family members regulate various biological processes, such as cell proliferation and tumorigenesis. FOXD, a FOX protein subfamily, is associated with poor prognosis for various cancers. However, the potential clinical value of FOXD subfamily members in colorectal cancer (CRC) has not yet been elucidated. Therefore, in this study, we aimed to determine the role of the FOXD subfamily members in CRC development.</p><p><strong>Methods: </strong>Using HTSeq-count data, clinical data, and single-nucleotide polymorphisms (obtained from The Cancer Genome Atlas Project), and bioinformatics analyses (using DESEQ2 software), we identified differentially expressed genes (DEGs) in CRC. Next, each DEG expression was validated <i>in vitro</i> using reverse transcription-quantitative polymerase chain reaction, western blotting, and immunohistochemistry (IHC).</p><p><strong>Results: </strong>Among the FOXD subfamily members, the area under the receiver operating characteristic curve of FOXD3 was 0.949, indicating that FOXD3 has a high overall diagnostic accuracy for CRC. Gene Set Enrichment Analysis revealed that FOXD-DEGs were mainly related to pathways such as cytokine, cytokine, and extracellular matrix receptor interactions. Kaplan-Meier curves and nomograms showed that FOXD1, FOXD3, and FOXD4 were prognostically significant. In conclusion, FOXD subfamily members (especially FOXD3) could serve as diagnostic and prognostic biomarkers for CRC and an immunotherapy target in patients with CRC.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for recovery from oculomotor nerve palsy after aneurysm surgery: a meta-analysis.","authors":"Yuan Li, Ming Zhao, Xuemei Li, Tiejuan Liu, Lin Zheng, Deyu Hu, Tongyan Liu, Lingyun Zhou","doi":"10.7717/peerj.18207","DOIUrl":"10.7717/peerj.18207","url":null,"abstract":"<p><strong>Background: </strong>Risk factors for recovery from oculomotor nerve palsy (ONP) after aneurysm surgery explored by meta-analysis.</p><p><strong>Methods: </strong>The PubMed, Embase, web of science, Cochrane library, China Knowledge, Wan fang, and VIP databases were searched for case-control or cohort studies on risk factors of oculomotor nerve palsy recovery after aneurysm surgery, with a cut-off date of 14 February 2024, and data were analyzed using Stata 15.</p><p><strong>Result: </strong>A total of 12 articles involving 866 individuals were included, meta-analysis results suggesting that gender (OR = 0.75, 95% CI [0.51-1.10]), age (OR = 1.00, 95% CI [0.93-1.07]), aneurysm size (OR = 0.85, 95% CI [-0.71 to 1.01]), treatment time (OR = 1.01, 95% CI [0.91-1.13]) is not a risk factor for recovery of motor nerve palsy after aneurysm surgery. Preoperative complete ONP (OR = 2.27, 95% CI [1.07-4.81]), surgery (OR = 9.88, 95% CI [2.53-38.57]), subarachnoid hemorrhage (OR = 1.29, 95% CI [1.06-1.56]) is a risk factor for recovery of motor nerve palsy after aneurysm surgery.</p><p><strong>Conclusion: </strong>Based on the results of the studies we included, we found that complete ONP before surgery led to poorer recovery, but patients with post-operative and subarachnoid hemorrhage had better recovery.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clocks at a snail pace: biological rhythms in terrestrial gastropods.","authors":"Rodrigo Brincalepe Salvador, Barbara Mizumo Tomotani","doi":"10.7717/peerj.18318","DOIUrl":"10.7717/peerj.18318","url":null,"abstract":"<p><p>Biological rhythms are ubiquitous across the tree of life. Organisms must allocate their activities into moments of the day and of the season that will increase their probability of surviving and reproducing, which is done in the form of daily and annual rhythms. So far, the vast majority of studies on biological rhythms have focused on classical laboratory model species. Still, the use of non-model species is gaining traction, as part of an effort to achieve a more holistic understanding of clock/calendar mechanisms in the \"real world\" but this requires species that can be studied in both the lab and in nature. Terrestrial gastropods, <i>i.e</i>., land snails and slugs, have the potential to be exciting models for the study of biological rhythms in nature. Therefore, we provide a review of the research on biological rhythms in terrestrial gastropods, with a focus on ecology and evolution. We present the state of the art in the field while giving a historical perspective of the studies, exploring each of the main lineages of terrestrial gastropods. We also point out some interesting directions that future studies could take to fill some of the more urgent gaps in current knowledge. We hope that our contribution will renew interest in this area and spark novel projects.</p>","PeriodicalId":19799,"journal":{"name":"PeerJ","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}